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Items: 1 to 50 of 120

1.

The SH3 domains of the protein kinases ITK and LCK compete for adjacent sites on T cell-specific adapter protein.

Andersen TCB, Kristiansen PE, Huszenicza Z, Johansson MU, Gopalakrishnan RP, Kjelstrup H, Boyken S, Sundvold-Gjerstad V, Granum S, Sørli M, Backe PH, Fulton DB, Karlsson BG, Andreotti AH, Spurkland A.

J Biol Chem. 2019 Oct 18;294(42):15480-15494. doi: 10.1074/jbc.RA119.008318. Epub 2019 Sep 4.

PMID:
31484725
2.

Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd.

Abrahamsen G, Sundvold-Gjerstad V, Habtamu M, Bogen B, Spurkland A.

Sci Rep. 2018 Sep 6;8(1):13319. doi: 10.1038/s41598-018-31510-6.

3.

In vitro analysis of antigen induced T cell-monocyte conjugates by imaging flow cytometry.

Habtamu M, Abebe M, Aseffa A, Dyrhol-Riise AM, Spurkland A, Abrahamsen G.

J Immunol Methods. 2018 Sep;460:93-100. doi: 10.1016/j.jim.2018.06.014. Epub 2018 Jul 4.

4.

CD6 and Linker of Activated T Cells are Potential Interaction Partners for T Cell-Specific Adaptor Protein.

Hem CD, Ekornhol M, Granum S, Sundvold-Gjerstad V, Spurkland A.

Scand J Immunol. 2017 Feb;85(2):104-112. doi: 10.1111/sji.12513.

5.

The endothelial adaptor molecule TSAd is required for VEGF-induced angiogenic sprouting through junctional c-Src activation.

Gordon EJ, Fukuhara D, Weström S, Padhan N, Sjöström EO, van Meeteren L, He L, Orsenigo F, Dejana E, Bentley K, Spurkland A, Claesson-Welsh L.

Sci Signal. 2016 Jul 19;9(437):ra72. doi: 10.1126/scisignal.aad9256.

PMID:
27436360
6.

The multiple sclerosis susceptibility genes TAGAP and IL2RA are regulated by vitamin D in CD4+ T cells.

Berge T, Leikfoss IS, Brorson IS, Bos SD, Page CM, Gustavsen MW, Bjølgerud A, Holmøy T, Celius EG, Damoiseaux J, Smolders J, Harbo HF, Spurkland A.

Genes Immun. 2016 Mar;17(2):118-27. doi: 10.1038/gene.2015.61. Epub 2016 Jan 14.

7.

Class II HLA interactions modulate genetic risk for multiple sclerosis.

Moutsianas L, Jostins L, Beecham AH, Dilthey AT, Xifara DK, Ban M, Shah TS, Patsopoulos NA, Alfredsson L, Anderson CA, Attfield KE, Baranzini SE, Barrett J, Binder TMC, Booth D, Buck D, Celius EG, Cotsapas C, D'Alfonso S, Dendrou CA, Donnelly P, Dubois B, Fontaine B, Fugger L, Goris A, Gourraud PA, Graetz C, Hemmer B, Hillert J; International IBD Genetics Consortium (IIBDGC), Kockum I, Leslie S, Lill CM, Martinelli-Boneschi F, Oksenberg JR, Olsson T, Oturai A, Saarela J, Søndergaard HB, Spurkland A, Taylor B, Winkelmann J, Zipp F, Haines JL, Pericak-Vance MA, Spencer CCA, Stewart G, Hafler DA, Ivinson AJ, Harbo HF, Hauser SL, De Jager PL, Compston A, McCauley JL, Sawcer S, McVean G.

Nat Genet. 2015 Oct;47(10):1107-1113. doi: 10.1038/ng.3395. Epub 2015 Sep 7.

8.

Multiple Sclerosis Risk Allele in CLEC16A Acts as an Expression Quantitative Trait Locus for CLEC16A and SOCS1 in CD4+ T Cells.

Leikfoss IS, Keshari PK, Gustavsen MW, Bjølgerud A, Brorson IS, Celius EG, Spurkland A, Bos SD, Harbo HF, Berge T.

PLoS One. 2015 Jul 23;10(7):e0132957. doi: 10.1371/journal.pone.0132957. eCollection 2015.

9.

T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells.

Hem CD, Sundvold-Gjerstad V, Granum S, Koll L, Abrahamsen G, Buday L, Spurkland A.

Cell Commun Signal. 2015 Jul 11;13:31. doi: 10.1186/s12964-015-0109-7.

10.

Coordinated expression of DNAM-1 and LFA-1 in educated NK cells.

Enqvist M, Ask EH, Forslund E, Carlsten M, Abrahamsen G, Béziat V, Andersson S, Schaffer M, Spurkland A, Bryceson Y, Önfelt B, Malmberg KJ.

J Immunol. 2015 May 1;194(9):4518-27. doi: 10.4049/jimmunol.1401972. Epub 2015 Mar 30.

11.

Reduced MCMV Δm157 viral clearance in the absence of TSAd.

Moussa P, Abrahamsen G, Fodil N, Gopalakrishnan RP, Mancini M, Dissen E, Sæther PC, Wiltshire SA, Boivin GA, Caignard G, Spurkland A, Vidal SM.

Sci Rep. 2015 Mar 18;5:9219. doi: 10.1038/srep09219.

12.

Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy.

Eriksen AB, Torgersen ML, Holm KL, Abrahamsen G, Spurkland A, Moskaug JØ, Simonsen A, Blomhoff HK.

Autophagy. 2015;11(3):460-71. doi: 10.1080/15548627.2015.1009797.

13.

Retinoic acid enhances the levels of IL-10 in TLR-stimulated B cells from patients with relapsing-remitting multiple sclerosis.

Eriksen AB, Berge T, Gustavsen MW, Leikfoss IS, Bos SD, Spurkland A, Harbo HF, Blomhoff HK.

J Neuroimmunol. 2015 Jan 15;278:11-8. doi: 10.1016/j.jneuroim.2014.11.019. Epub 2014 Nov 24.

PMID:
25595247
14.

The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192.

Granum S, Sundvold-Gjerstad V, Gopalakrishnan RP, Berge T, Koll L, Abrahamsen G, Sørlie M, Spurkland A.

Sci Signal. 2014 Dec 9;7(355):ra118. doi: 10.1126/scisignal.2005384.

PMID:
25492967
15.

Expression of the T cell-specific adapter protein in human tissues.

Pandya AD, Leergaard TB, Dissen E, Haraldsen G, Spurkland A.

Scand J Immunol. 2014 Sep;80(3):169-79. doi: 10.1111/sji.12199.

16.

Solubility of recombinant Src homology 2 domains expressed in E. coli can be predicted by TANGO.

Andersen TC, Lindsjø K, Hem CD, Koll L, Kristiansen PE, Skjeldal L, Andreotti AH, Spurkland A.

BMC Biotechnol. 2014 Jan 14;14:3. doi: 10.1186/1472-6750-14-3.

17.

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

International Multiple Sclerosis Genetics Consortium (IMSGC), Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, Cotsapas C, Shah TS, Spencer C, Booth D, Goris A, Oturai A, Saarela J, Fontaine B, Hemmer B, Martin C, Zipp F, D'Alfonso S, Martinelli-Boneschi F, Taylor B, Harbo HF, Kockum I, Hillert J, Olsson T, Ban M, Oksenberg JR, Hintzen R, Barcellos LF; Wellcome Trust Case Control Consortium 2 (WTCCC2); International IBD Genetics Consortium (IIBDGC), Agliardi C, Alfredsson L, Alizadeh M, Anderson C, Andrews R, Søndergaard HB, Baker A, Band G, Baranzini SE, Barizzone N, Barrett J, Bellenguez C, Bergamaschi L, Bernardinelli L, Berthele A, Biberacher V, Binder TM, Blackburn H, Bomfim IL, Brambilla P, Broadley S, Brochet B, Brundin L, Buck D, Butzkueven H, Caillier SJ, Camu W, Carpentier W, Cavalla P, Celius EG, Coman I, Comi G, Corrado L, Cosemans L, Cournu-Rebeix I, Cree BA, Cusi D, Damotte V, Defer G, Delgado SR, Deloukas P, di Sapio A, Dilthey AT, Donnelly P, Dubois B, Duddy M, Edkins S, Elovaara I, Esposito F, Evangelou N, Fiddes B, Field J, Franke A, Freeman C, Frohlich IY, Galimberti D, Gieger C, Gourraud PA, Graetz C, Graham A, Grummel V, Guaschino C, Hadjixenofontos A, Hakonarson H, Halfpenny C, Hall G, Hall P, Hamsten A, Harley J, Harrower T, Hawkins C, Hellenthal G, Hillier C, Hobart J, Hoshi M, Hunt SE, Jagodic M, Jelčić I, Jochim A, Kendall B, Kermode A, Kilpatrick T, Koivisto K, Konidari I, Korn T, Kronsbein H, Langford C, Larsson M, Lathrop M, Lebrun-Frenay C, Lechner-Scott J, Lee MH, Leone MA, Leppä V, Liberatore G, Lie BA, Lill CM, Lindén M, Link J, Luessi F, Lycke J, Macciardi F, Männistö S, Manrique CP, Martin R, Martinelli V, Mason D, Mazibrada G, McCabe C, Mero IL, Mescheriakova J, Moutsianas L, Myhr KM, Nagels G, Nicholas R, Nilsson P, Piehl F, Pirinen M, Price SE, Quach H, Reunanen M, Robberecht W, Robertson NP, Rodegher M, Rog D, Salvetti M, Schnetz-Boutaud NC, Sellebjerg F, Selter RC, Schaefer C, Shaunak S, Shen L, Shields S, Siffrin V, Slee M, Sorensen PS, Sorosina M, Sospedra M, Spurkland A, Strange A, Sundqvist E, Thijs V, Thorpe J, Ticca A, Tienari P, van Duijn C, Visser EM, Vucic S, Westerlind H, Wiley JS, Wilkins A, Wilson JF, Winkelmann J, Zajicek J, Zindler E, Haines JL, Pericak-Vance MA, Ivinson AJ, Stewart G, Hafler D, Hauser SL, Compston A, McVean G, De Jager P, Sawcer SJ, McCauley JL.

Nat Genet. 2013 Nov;45(11):1353-60. doi: 10.1038/ng.2770. Epub 2013 Sep 29.

18.

B-cell tolerance to the B-cell receptor variable regions.

Jacobsen JT, Sundvold-Gjerstad V, Skjeldal FM, Andersen JT, Abrahamsen G, Bakke O, Spurkland A, Bogen B.

Eur J Immunol. 2013 Oct;43(10):2577-87. doi: 10.1002/eji.201243203. Epub 2013 Jul 19.

19.

Multiple sclerosis-associated single-nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in the thymus.

Leikfoss IS, Mero IL, Dahle MK, Lie BA, Harbo HF, Spurkland A, Berge T.

Genes Immun. 2013 Jan;14(1):62-6. doi: 10.1038/gene.2012.52. Epub 2012 Nov 15.

PMID:
23151489
20.

SH2D2A modulates T cell mediated protection to a B cell derived tumor in transgenic mice.

Berge T, Grønningsæter IH, Lorvik KB, Abrahamsen G, Granum S, Sundvold-Gjerstad V, Corthay A, Bogen B, Spurkland A.

PLoS One. 2012;7(10):e48239. doi: 10.1371/journal.pone.0048239. Epub 2012 Oct 29.

21.

VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.

Sun Z, Li X, Massena S, Kutschera S, Padhan N, Gualandi L, Sundvold-Gjerstad V, Gustafsson K, Choy WW, Zang G, Quach M, Jansson L, Phillipson M, Abid MR, Spurkland A, Claesson-Welsh L.

J Exp Med. 2012 Jul 2;209(7):1363-77. doi: 10.1084/jem.20111343. Epub 2012 Jun 11.

22.

[New gene map for multiple sclerosis].

Harbo HF, Lorentzen AR, Lie BA, Celius EG, Spurkland A.

Tidsskr Nor Laegeforen. 2011 Nov 1;131(21):2126-30. doi: 10.4045/tidsskr.10.0823. Review. Norwegian.

23.

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

International Multiple Sclerosis Genetics Consortium; Wellcome Trust Case Control Consortium 2, Sawcer S, Hellenthal G, Pirinen M, Spencer CC, Patsopoulos NA, Moutsianas L, Dilthey A, Su Z, Freeman C, Hunt SE, Edkins S, Gray E, Booth DR, Potter SC, Goris A, Band G, Oturai AB, Strange A, Saarela J, Bellenguez C, Fontaine B, Gillman M, Hemmer B, Gwilliam R, Zipp F, Jayakumar A, Martin R, Leslie S, Hawkins S, Giannoulatou E, D'alfonso S, Blackburn H, Martinelli Boneschi F, Liddle J, Harbo HF, Perez ML, Spurkland A, Waller MJ, Mycko MP, Ricketts M, Comabella M, Hammond N, Kockum I, McCann OT, Ban M, Whittaker P, Kemppinen A, Weston P, Hawkins C, Widaa S, Zajicek J, Dronov S, Robertson N, Bumpstead SJ, Barcellos LF, Ravindrarajah R, Abraham R, Alfredsson L, Ardlie K, Aubin C, Baker A, Baker K, Baranzini SE, Bergamaschi L, Bergamaschi R, Bernstein A, Berthele A, Boggild M, Bradfield JP, Brassat D, Broadley SA, Buck D, Butzkueven H, Capra R, Carroll WM, Cavalla P, Celius EG, Cepok S, Chiavacci R, Clerget-Darpoux F, Clysters K, Comi G, Cossburn M, Cournu-Rebeix I, Cox MB, Cozen W, Cree BA, Cross AH, Cusi D, Daly MJ, Davis E, de Bakker PI, Debouverie M, D'hooghe MB, Dixon K, Dobosi R, Dubois B, Ellinghaus D, Elovaara I, Esposito F, Fontenille C, Foote S, Franke A, Galimberti D, Ghezzi A, Glessner J, Gomez R, Gout O, Graham C, Grant SF, Guerini FR, Hakonarson H, Hall P, Hamsten A, Hartung HP, Heard RN, Heath S, Hobart J, Hoshi M, Infante-Duarte C, Ingram G, Ingram W, Islam T, Jagodic M, Kabesch M, Kermode AG, Kilpatrick TJ, Kim C, Klopp N, Koivisto K, Larsson M, Lathrop M, Lechner-Scott JS, Leone MA, Leppä V, Liljedahl U, Bomfim IL, Lincoln RR, Link J, Liu J, Lorentzen AR, Lupoli S, Macciardi F, Mack T, Marriott M, Martinelli V, Mason D, McCauley JL, Mentch F, Mero IL, Mihalova T, Montalban X, Mottershead J, Myhr KM, Naldi P, Ollier W, Page A, Palotie A, Pelletier J, Piccio L, Pickersgill T, Piehl F, Pobywajlo S, Quach HL, Ramsay PP, Reunanen M, Reynolds R, Rioux JD, Rodegher M, Roesner S, Rubio JP, Rückert IM, Salvetti M, Salvi E, Santaniello A, Schaefer CA, Schreiber S, Schulze C, Scott RJ, Sellebjerg F, Selmaj KW, Sexton D, Shen L, Simms-Acuna B, Skidmore S, Sleiman PM, Smestad C, Sørensen PS, Søndergaard HB, Stankovich J, Strange RC, Sulonen AM, Sundqvist E, Syvänen AC, Taddeo F, Taylor B, Blackwell JM, Tienari P, Bramon E, Tourbah A, Brown MA, Tronczynska E, Casas JP, Tubridy N, Corvin A, Vickery J, Jankowski J, Villoslada P, Markus HS, Wang K, Mathew CG, Wason J, Palmer CN, Wichmann HE, Plomin R, Willoughby E, Rautanen A, Winkelmann J, Wittig M, Trembath RC, Yaouanq J, Viswanathan AC, Zhang H, Wood NW, Zuvich R, Deloukas P, Langford C, Duncanson A, Oksenberg JR, Pericak-Vance MA, Haines JL, Olsson T, Hillert J, Ivinson AJ, De Jager PL, Peltonen L, Stewart GJ, Hafler DA, Hauser SL, McVean G, Donnelly P, Compston A.

Nature. 2011 Aug 10;476(7359):214-9. doi: 10.1038/nature10251.

24.

Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymus.

Mero IL, Ban M, Lorentzen ÅR, Smestad C, Celius EG, Sæther H, Saeedi H, Viken MK, Skinningsrud B, Undlien DE, Aarseth J, Myhr KM, Granum S, Spurkland A, Sawcer S, Compston A, Lie BA, Harbo HF.

Genes Immun. 2011 Apr;12(3):191-8. doi: 10.1038/gene.2010.59. Epub 2010 Dec 23.

PMID:
21179112
25.

Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis.

International Multiple Sclerosis Genetics Consortium (IMSGC), Booth DR, Heard RN, Stewart GJ, Cox M, Scott RJ, Lechner-Scott J, Goris A, Dobosi R, Dubois B, Saarela J, Leppä V, Peltonen L, Pirttila T, Cournu-Rebeix I, Fontaine B, Bergamaschi L, D'Alfonso S, Leone M, Lorentzen AR, Harbo HF, Celius EG, Spurkland A, Link J, Kockum I, Olsson T, Hillert J, Ban M, Baker A, Kemppinen A, Sawcer S, Compston A, Robertson NP, De Jager PL, Hafler DA, Barcellos LF, Ivinson AJ, McCauley JL, Pericak-Vance MA, Oksenberg JR, Hauser SL, Sexton D, Haines J.

Nat Genet. 2010 Jun;42(6):469-70; author reply 470-1. doi: 10.1038/ng0610-469. No abstract available.

26.

Expression of the T-cell-specific adapter protein in oral epithelium.

Kolltveit KM, Schreurs O, Ostrem J, Søland TM, Khuu C, Berge T, Messelt E, Hayashi K, Granum S, Spurkland A, Schenck K.

Eur J Oral Sci. 2010 Apr;118(2):159-67. doi: 10.1111/j.1600-0722.2010.00719.x.

PMID:
20487005
27.

A role for VAV1 in experimental autoimmune encephalomyelitis and multiple sclerosis.

Jagodic M, Colacios C, Nohra R, Dejean AS, Beyeen AD, Khademi M, Casemayou A, Lamouroux L, Duthoit C, Papapietro O, Sjöholm L, Bernard I, Lagrange D, Dahlman I, Lundmark F, Oturai AB, Soendergaard HB, Kemppinen A, Saarela J, Tienari PJ, Harbo HF, Spurkland A, Ramagopalan SV, Sadovnick DA, Ebers GC, Seddighzadeh M, Klareskog L, Alfredsson L, Padyukov L, Hillert J, Clanet M, Edan G, Fontaine B, Fournié GJ, Kockum I, Saoudi A, Olsson T.

Sci Transl Med. 2009 Dec 9;1(10):10ra21. doi: 10.1126/scitranslmed.3000278.

28.

T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.

Berge T, Sundvold-Gjerstad V, Granum S, Andersen TC, Holthe GB, Claesson-Welsh L, Andreotti AH, Inngjerdingen M, Spurkland A.

PLoS One. 2010 Mar 18;5(3):e9761. doi: 10.1371/journal.pone.0009761.

29.

A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis.

Mero IL, Lorentzen AR, Ban M, Smestad C, Celius EG, Aarseth JH, Myhr KM, Link J, Hillert J, Olsson T, Kockum I, Masterman T, Oturai AB, Søndergaard HB, Sellebjerg F, Saarela J, Kemppinen A, Elovaara I, Spurkland A, Dudbridge F, Lie BA, Harbo HF.

Eur J Hum Genet. 2010 Apr;18(4):502-4. doi: 10.1038/ejhg.2009.195. Epub 2009 Nov 4.

30.

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.

Lorentzen AR, Karlsen TH, Olsson M, Smestad C, Mero IL, Woldseth B, Sun JY, Senitzer D, Celius EG, Thorsby E, Spurkland A, Lie BA, Harbo HF.

Ann Neurol. 2009 Jun;65(6):658-66. doi: 10.1002/ana.21695.

PMID:
19630074
31.

Genetic and molecular approaches to the immunopathogenesis of multiple sclerosis: an update.

Holmøy T, Harbo H, Vartdal F, Spurkland A.

Curr Mol Med. 2009 Jun;9(5):591-611. Review.

PMID:
19601809
32.

Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor.

Ban M, Goris A, Lorentzen AR, Baker A, Mihalova T, Ingram G, Booth DR, Heard RN, Stewart GJ, Bogaert E, Dubois B, Harbo HF, Celius EG, Spurkland A, Strange R, Hawkins C, Robertson NP, Dudbridge F, Wason J, De Jager PL, Hafler D, Rioux JD, Ivinson AJ, McCauley JL, Pericak-Vance M, Oksenberg JR, Hauser SL, Sexton D, Haines J, Sawcer S; Wellcome Trust Case-Control Consortium (WTCCC), Compston A.

Eur J Hum Genet. 2009 Oct;17(10):1309-13. doi: 10.1038/ejhg.2009.41. Epub 2009 Mar 18.

33.

Parent of origin in multiple sclerosis: understanding inheritance in complex neurologic diseases.

Kantarci OH, Spurkland A.

Neurology. 2008 Sep 9;71(11):786-7. doi: 10.1212/01.wnl.0000325476.61600.2b. No abstract available.

PMID:
18779508
34.

The SH2D2A gene and susceptibility to multiple sclerosis.

Lorentzen AR, Smestad C, Lie BA, Oturai AB, Akesson E, Saarela J, Myhr KM, Vartdal F, Celius EG, Sørensen PS, Hillert J, Spurkland A, Harbo HF.

J Neuroimmunol. 2008 Jul 15;197(2):152-8. doi: 10.1016/j.jneuroim.2008.04.037. Epub 2008 Jun 12.

PMID:
18554728
35.

Modulation of Lck function through multisite docking to T cell-specific adapter protein.

Granum S, Andersen TC, Sørlie M, Jørgensen M, Koll L, Berge T, Lea T, Fleckenstein B, Spurkland A, Sundvold-Gjerstad V.

J Biol Chem. 2008 Aug 8;283(32):21909-19. doi: 10.1074/jbc.M800871200. Epub 2008 Jun 9.

36.

Expression of SH2D2A in T-cells is regulated both at the transcriptional and translational level.

Kolltveit KM, Granum S, Aasheim HC, Forsbring M, Sundvold-Gjerstad V, Dai KZ, Molberg O, Schjetne KW, Bogen B, Shapiro VS, Johansen FE, Schenck K, Spurkland A.

Mol Immunol. 2008 Apr;45(8):2380-90. Epub 2007 Dec 26.

PMID:
18160104
37.

X chromosome inactivation in females with multiple sclerosis.

Knudsen GP, Harbo HF, Smestad C, Celius EG, Akesson E, Oturai A, Ryder LP, Spurkland A, Ørstavik KH.

Eur J Neurol. 2007 Dec;14(12):1392-6. Epub 2007 Oct 26.

PMID:
17970735
38.

The impact of HLA-A and -DRB1 on age at onset, disease course and severity in Scandinavian multiple sclerosis patients.

Smestad C, Brynedal B, Jonasdottir G, Lorentzen AR, Masterman T, Akesson E, Spurkland A, Lie BA, Palmgren J, Celius EG, Hillert J, Harbo HF.

Eur J Neurol. 2007 Aug;14(8):835-40.

PMID:
17662002
39.

A follow-up study of Nordic multiple sclerosis candidate gene regions.

Datta P, Harbo HF, Ryder LP, Akesson E, Benedikz J, Celius EG, Andersen O, Myhr KM, Sandberg-Wollheim M, Hillert J, Svejgaard A, Sorensen PS, Spurkland A, Oturai A.

Mult Scler. 2007 Jun;13(5):584-9. Epub 2007 Feb 9.

PMID:
17548436
40.

Genetics in multiple sclerosis: past and future perspectives.

Harbo HF, Spurkland A.

Acta Neurol Scand Suppl. 2007;187:34-8. Review.

PMID:
17419826
41.

Primary sclerosing cholangitis is associated with extended HLA-DR3 and HLA-DR6 haplotypes.

Wiencke K, Karlsen TH, Boberg KM, Thorsby E, Schrumpf E, Lie BA, Spurkland A.

Tissue Antigens. 2007 Feb;69(2):161-9.

PMID:
17257319
42.

Molecular genetic studies of natives on Easter Island: evidence of an early European and Amerindian contribution to the Polynesian gene pool.

Lie BA, Dupuy BM, Spurkland A, Fernández-Viña MA, Hagelberg E, Thorsby E.

Tissue Antigens. 2007 Jan;69(1):10-8.

PMID:
17212703
43.

Linkage disequilibrium screening for multiple sclerosis implicates JAG1 and POU2AF1 as susceptibility genes in Europeans.

Games Collaborative Group, Ban M, Booth D, Heard R, Stewart G, Goris A, Vandenbroeck K, Dubois B, Laaksonen M, Ilonen J, Alizadeh M, Edan G, Babron MC, Brassat D, Clanet M, Cournu-Rebeix I, Fontaine B, Semana G, Goedde R, Epplen J, Weber A, Infante-Duarte C, Zipp F, Rajda C, Bencsik K, Vécsei L, Heggarty S, Graham C, Hawkins S, Liguori M, Momigliano-Richiardi P, Caputo D, Grimaldi LM, Leone M, Massacesi L, Milanese C, Salvetti M, Savettieri G, Trojano M, Bielecki B, Mycko MP, Selmaj K, Santos M, Maciel P, Pereira C, Silva A, Silva BM, Coraddu F, Marrosu MG, Akesson E, Hillert J, Datta P, Oturai A, Harbo HF, Spurkland A, Goertsches R, Villoslada P, Eraksoy M, Hensiek A, Compston A, Setakis E, Gray J, Yeo TW, Sawcer S.

J Neuroimmunol. 2006 Oct;179(1-2):108-16. Epub 2006 Aug 24. Erratum in: J Neuroimmunol. 2007 Sep;189(1-2):175-6. multiple author names added.

PMID:
16934875
44.

Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7.

Granum S, Sundvold-Gjerstad V, Dai KZ, Kolltveit KM, Hildebrand K, Huitfeldt HS, Lea T, Spurkland A.

BMC Immunol. 2006 Jul 13;7:15.

45.

Coding region polymorphisms in T cell signal transduction genes. Prevalence and association to development of multiple sclerosis.

Harbo HF, Ekstrøm PO, Lorentzen AR, Sundvold-Gjerstad V, Celius EG, Sawcer S, Spurkland A.

J Neuroimmunol. 2006 Aug;177(1-2):40-5. Epub 2006 Jun 9.

PMID:
16764945
46.

Mapping genes and pathways in autoimmune disease.

Spurkland A, Sollid LM.

Trends Immunol. 2006 Jul;27(7):336-42. Epub 2006 Jun 5. Review.

PMID:
16753344
47.

No major effect of the CD28/CTLA4/ICOS gene region on susceptibility to primary sclerosing cholangitis.

Wiencke K, Boberg KM, Donaldson P, Harbo H, Ling V, Schrumpf E, Spurkland A.

Scand J Gastroenterol. 2006 May;41(5):586-91.

PMID:
16638702
48.

A high-density screen for linkage in multiple sclerosis.

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