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Items: 27


Lack of selective resistance of influenza A virus in presence of host-targeted antiviral, UV-4B.

Warfield KL, Schaaf KR, DeWald LE, Spurgers KB, Wang W, Stavale E, Mendenhall M, Shilts MH, Stockwell TB, Barnard DL, Ramstedt U, Das SR.

Sci Rep. 2019 May 16;9(1):7484. doi: 10.1038/s41598-019-43030-y.


1,5-Iodonaphthyl azide-inactivated V3526 protects against aerosol challenge with virulent venezuelan equine encephalitis virus.

Gupta P, Sharma A, Spurgers KB, Bakken RR, Eccleston LT, Cohen JW, Honnold SP, Glass PJ, Maheshwari RK.

Vaccine. 2016 May 27;34(25):2762-5. doi: 10.1016/j.vaccine.2016.04.049. Epub 2016 Apr 26.


Eastern equine encephalitis virus in mice II: pathogenesis is dependent on route of exposure.

Honnold SP, Mossel EC, Bakken RR, Lind CM, Cohen JW, Eccleston LT, Spurgers KB, Erwin-Cohen R, Glass PJ, Maheshwari RK.

Virol J. 2015 Sep 30;12:154. doi: 10.1186/s12985-015-0385-2.


Eastern equine encephalitis virus in mice I: clinical course and outcome are dependent on route of exposure.

Honnold SP, Mossel EC, Bakken RR, Fisher D, Lind CM, Cohen JW, Eccleston LT, Spurgers KB, Erwin-Cohen R, Bradfute SB, Maheshwari RK, Glass PJ.

Virol J. 2015 Sep 29;12:152. doi: 10.1186/s12985-015-0386-1.


Second generation inactivated eastern equine encephalitis virus vaccine candidates protect mice against a lethal aerosol challenge.

Honnold SP, Bakken RR, Fisher D, Lind CM, Cohen JW, Eccleston LT, Spurgers KB, Maheshwari RK, Glass PJ.

PLoS One. 2014 Aug 12;9(8):e104708. doi: 10.1371/journal.pone.0104708. eCollection 2014.


HSPA5 is an essential host factor for Ebola virus infection.

Reid SP, Shurtleff AC, Costantino JA, Tritsch SR, Retterer C, Spurgers KB, Bavari S.

Antiviral Res. 2014 Sep;109:171-4. doi: 10.1016/j.antiviral.2014.07.004. Epub 2014 Jul 11.


Validation of a cell-based ELISA as a screening tool identifying anti-alphavirus small-molecule inhibitors.

Spurgers KB, Hurt CR, Cohen JW, Eccelston LT, Lind CM, Lingappa VR, Glass PJ.

J Virol Methods. 2013 Oct;193(1):226-31. doi: 10.1016/j.jviromet.2013.06.007. Epub 2013 Jun 10.


PI3 Kinase inhibition on TRAIL-induced apoptosis correlates with androgen-sensitivity and p21 expression in prostate cancer cells.

Kadowaki Y, Chari NS, Teo AE, Hashi A, Spurgers KB, McDonnell TJ.

Apoptosis. 2011 Jun;16(6):627-35. doi: 10.1007/s10495-011-0591-3.


Identification of essential filovirion-associated host factors by serial proteomic analysis and RNAi screen.

Spurgers KB, Alefantis T, Peyser BD, Ruthel GT, Bergeron AA, Costantino JA, Enterlein S, Kota KP, Boltz RC, Aman MJ, Delvecchio VG, Bavari S.

Mol Cell Proteomics. 2010 Dec;9(12):2690-703. doi: 10.1074/mcp.M110.003418. Epub 2010 Aug 11.


Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin.

Radoshitzky SR, Dong L, Chi X, Clester JC, Retterer C, Spurgers K, Kuhn JH, Sandwick S, Ruthel G, Kota K, Boltz D, Warren T, Kranzusch PJ, Whelan SP, Bavari S.

J Virol. 2010 Oct;84(20):10569-80. doi: 10.1128/JVI.00103-10. Epub 2010 Aug 4.


Development of high-content imaging assays for lethal viral pathogens.

Panchal RG, Kota KP, Spurgers KB, Ruthel G, Tran JP, Boltz RC, Bavari S.

J Biomol Screen. 2010 Aug;15(7):755-65. doi: 10.1177/1087057110374357. Epub 2010 Jul 16.


Burkholderia mallei tssM encodes a putative deubiquitinase that is secreted and expressed inside infected RAW 264.7 murine macrophages.

Shanks J, Burtnick MN, Brett PJ, Waag DM, Spurgers KB, Ribot WJ, Schell MA, Panchal RG, Gherardini FC, Wilkinson KD, Deshazer D.

Infect Immun. 2009 Apr;77(4):1636-48. doi: 10.1128/IAI.01339-08. Epub 2009 Jan 21.


Oligonucleotide antiviral therapeutics: antisense and RNA interference for highly pathogenic RNA viruses.

Spurgers KB, Sharkey CM, Warfield KL, Bavari S.

Antiviral Res. 2008 Apr;78(1):26-36. doi: 10.1016/j.antiviral.2007.12.008. Epub 2008 Jan 14. Review.


Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression.

Spurgers KB, Gold DL, Coombes KR, Bohnenstiehl NL, Mullins B, Meyn RE, Logothetis CJ, McDonnell TJ.

J Biol Chem. 2006 Sep 1;281(35):25134-42. Epub 2006 Jun 23.


Molecular mediators of cell death in multistep carcinogenesis: a path to targeted therapy.

Spurgers KB, Chari NS, Bohnenstiehl NL, McDonnell TJ.

Cell Death Differ. 2006 Aug;13(8):1360-70. Epub 2006 Jun 9. Review.


Combined laser capture microdissection and serial analysis of gene expression from human tissue samples.

Cho-Vega JH, Troncoso P, Do KA, Rago C, Wang X, Tsavachidis S, Medeiros LJ, Spurgers K, Logothetis C, McDonnell TJ.

Mod Pathol. 2005 Apr;18(4):577-84.


Suppressor of cytokine signaling 3 expression in anaplastic large cell lymphoma.

Cho-Vega JH, Rassidakis GZ, Amin HM, Tsioli P, Spurgers K, Remache YK, Vega F, Goy AH, Gilles F, Medeiros LJ.

Leukemia. 2004 Nov;18(11):1872-8.


GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells.

Honda T, Coppola S, Ghibelli L, Cho SH, Kagawa S, Spurgers KB, Brisbay SM, Roth JA, Meyn RE, Fang B, McDonnell TJ.

Cancer Gene Ther. 2004 Apr;11(4):249-55.


A comprehensive assessment of p53-responsive genes following adenoviral-p53 gene transfer in Bcl-2-expressing prostate cancer cells.

Spurgers KB, Coombes KR, Meyn RE, Gold DL, Logothetis CJ, Johnson TJ, McDonnell TJ.

Oncogene. 2004 Mar 4;23(9):1712-23.


Transcriptional regulation of bcl-2 mediated by the sonic hedgehog signaling pathway through gli-1.

Bigelow RL, Chari NS, Unden AB, Spurgers KB, Lee S, Roop DR, Toftgard R, McDonnell TJ.

J Biol Chem. 2004 Jan 9;279(2):1197-205. Epub 2003 Oct 10.


Regulation of Bcl-2 expression by dihydrotestosterone in hormone sensitive LNCaP-FGC prostate cancer cells.

Bruckheimer EM, Spurgers K, Weigel NL, Logothetis C, McDonnell TJ.

J Urol. 2003 Apr;169(4):1553-7.


A recombinant adenovirus expressing wild-type Bax induces apoptosis in prostate cancer cells independently of their Bcl-2 status and androgen sensitivity.

Honda T, Kagawa S, Spurgers KB, Gjertsen BT, Roth JA, Fang B, Lowe SL, Norris JS, Meyn RE, McDonnell TJ.

Cancer Biol Ther. 2002 Mar-Apr;1(2):163-7.


Restoration of bax in prostate cancer suppresses tumor growth and augments therapeutic cell death induction.

Honda T, Gjertsen BT, Spurgers KB, Briones F, Lee SJ, Hobbs ML, Meyn RE, Roth JA, Logothetis C, McDonnell TJ.

Anticancer Res. 2001 Sep-Oct;21(5):3141-6.


NF-kappaB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene.

Kurland JF, Kodym R, Story MD, Spurgers KB, McDonnell TJ, Meyn RE.

J Biol Chem. 2001 Nov 30;276(48):45380-6. Epub 2001 Sep 20.


Transfer of E2F-1 to human glioma cells results in transcriptional up-regulation of Bcl-2.

Gomez-Manzano C, Mitlianga P, Fueyo J, Lee HY, Hu M, Spurgers KB, Glass TL, Koul D, Liu TJ, McDonnell TJ, Yung WK.

Cancer Res. 2001 Sep 15;61(18):6693-7.


Prostate cancer: another piece to the molecular puzzle.

Spurgers K, Briones F, McDonnell TJ.

Adv Anat Pathol. 2000 Jan;7(1):9-12. Review. No abstract available.


Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes.

Bertram MJ, Bérubé NG, Hang-Swanson X, Ran Q, Leung JK, Bryce S, Spurgers K, Bick RJ, Baldini A, Ning Y, Clark LJ, Parkinson EK, Barrett JC, Smith JR, Pereira-Smith OM.

Mol Cell Biol. 1999 Feb;19(2):1479-85.

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