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Items: 50

1.

A Functional Immune System Is Required for the Systemic Genotoxic Effects of Localized Irradiation.

Lobachevsky PN, Ventura J, Giannakandropoulou L, Forrester H, Palazzolo JS, Haynes NM, Stevenson AW, Hall CJ, Mason J, Pollakis G, Pateras IS, Gorgoulis V, Terzoudi GI, Hamilton JA, Sprung CN, Georgakilas AG, Martin OA.

Int J Radiat Oncol Biol Phys. 2019 Apr 1;103(5):1184-1193. doi: 10.1016/j.ijrobp.2018.11.066. Epub 2018 Dec 6.

PMID:
30529375
2.

Localized Synchrotron Irradiation of Mouse Skin Induces Persistent Systemic Genotoxic and Immune Responses.

Ventura J, Lobachevsky PN, Palazzolo JS, Forrester H, Haynes NM, Ivashkevich A, Stevenson AW, Hall CJ, Ntargaras A, Kotsaris V, Pollakis GC, Potsi G, Skordylis K, Terzoudi G, Pateras IS, Gorgoulis VG, Georgakilas AG, Sprung CN, Martin OA.

Cancer Res. 2017 Nov 15;77(22):6389-6399. doi: 10.1158/0008-5472.CAN-17-1066. Epub 2017 Nov 7.

3.

N-cadherin identifies human endometrial epithelial progenitor cells by in vitro stem cell assays.

Nguyen HPT, Xiao L, Deane JA, Tan KS, Cousins FL, Masuda H, Sprung CN, Rosamilia A, Gargett CE.

Hum Reprod. 2017 Nov 1;32(11):2254-2268. doi: 10.1093/humrep/dex289.

PMID:
29040564
4.

Follistatin attenuates radiation-induced fibrosis in a murine model.

Forrester HB, de Kretser DM, Leong T, Hagekyriakou J, Sprung CN.

PLoS One. 2017 Mar 16;12(3):e0173788. doi: 10.1371/journal.pone.0173788. eCollection 2017.

5.

Potential strategies to ameliorate risk of radiotherapy-induced second malignant neoplasms.

Martin OA, Yin X, Forrester HB, Sprung CN, Martin RF.

Semin Cancer Biol. 2016 Jun;37-38:65-76. doi: 10.1016/j.semcancer.2015.12.003. Epub 2015 Dec 23. Review.

PMID:
26721424
6.

Assessment and Implications of Scattered Microbeam and Broadbeam Synchrotron Radiation for Bystander Effect Studies.

Lobachevsky P, Ivashkevich A, Forrester HB, Stevenson AW, Hall CJ, Sprung CN, Martin OA.

Radiat Res. 2015 Dec;184(6):650-9. doi: 10.1667/RR13720.1. Epub 2015 Dec 3.

PMID:
26632855
7.

Immunological markers that predict radiation toxicity.

Sprung CN, Forrester HB, Siva S, Martin OA.

Cancer Lett. 2015 Nov 28;368(2):191-7. doi: 10.1016/j.canlet.2015.01.045. Epub 2015 Feb 10. Review.

PMID:
25681035
8.

Identification of a radiation sensitivity gene expression profile in primary fibroblasts derived from patients who developed radiotherapy-induced fibrosis.

Forrester HB, Li J, Leong T, McKay MJ, Sprung CN.

Radiother Oncol. 2014 May;111(2):186-93. doi: 10.1016/j.radonc.2014.03.007. Epub 2014 May 13.

PMID:
24835153
9.

Intragenic controls utilizing radiation-induced alternative transcript regions improves gene expression biodosimetry.

Forrester HB, Sprung CN.

Radiat Res. 2014 Mar;181(3):314-23. doi: 10.1667/RR13501.1. Epub 2014 Mar 13.

PMID:
24625097
10.

Follistatin is induced by ionizing radiation and potentially predictive of radiosensitivity in radiation-induced fibrosis patient derived fibroblasts.

Forrester HB, Ivashkevich A, McKay MJ, Leong T, de Kretser DM, Sprung CN.

PLoS One. 2013 Oct 18;8(10):e77119. doi: 10.1371/journal.pone.0077119. eCollection 2013.

11.

Oxidative DNA damage caused by inflammation may link to stress-induced non-targeted effects.

Sprung CN, Ivashkevich A, Forrester HB, Redon CE, Georgakilas A, Martin OA.

Cancer Lett. 2015 Jan 1;356(1):72-81. doi: 10.1016/j.canlet.2013.09.008. Epub 2013 Sep 14. Review.

12.

Genome-wide analysis using exon arrays demonstrates an important role for expression of extra-cellular matrix, fibrotic control and tissue remodelling genes in Dupuytren's disease.

Forrester HB, Temple-Smith P, Ham S, de Kretser D, Southwick G, Sprung CN.

PLoS One. 2013;8(3):e59056. doi: 10.1371/journal.pone.0059056. Epub 2013 Mar 12.

13.

DNA repair genes: alternative transcription and gene expression at the exon level in response to the DNA damaging agent, ionizing radiation.

Forrester HB, Li J, Hovan D, Ivashkevich AN, Sprung CN.

PLoS One. 2012;7(12):e53358. doi: 10.1371/journal.pone.0053358. Epub 2012 Dec 28.

14.

Genome-wide transcription responses to synchrotron microbeam radiotherapy.

Sprung CN, Yang Y, Forrester HB, Li J, Zaitseva M, Cann L, Restall T, Anderson RL, Crosbie JC, Rogers PA.

Radiat Res. 2012 Oct;178(4):249-59. doi: 10.1667/RR2885.1. Epub 2012 Sep 13.

PMID:
22974124
16.

Alternative transcript initiation and splicing as a response to DNA damage.

Sprung CN, Li J, Hovan D, McKay MJ, Forrester HB.

PLoS One. 2011;6(10):e25758. doi: 10.1371/journal.pone.0025758. Epub 2011 Oct 19.

17.

DNA damage and repair kinetics after microbeam radiation therapy emulation in living cells using monoenergetic synchrotron X-ray microbeams.

Sprung CN, Cholewa M, Usami N, Kobayashi K, Crosbie JC.

J Synchrotron Radiat. 2011 Jul;18(Pt 4):630-6. doi: 10.1107/S0909049511011836. Epub 2011 May 14.

18.

Lymphoid and fibroblastic cell lineages from radiosensitive cancer patients: molecular analysis of DNA double strand break repair by major non-homologous end-joining sub-pathways.

McKay MJ, Withana N, Davey DS, Bishop D, Chao M, Sprung CN.

Asia Pac J Clin Oncol. 2011 Mar;7(1):17-26. doi: 10.1111/j.1743-7563.2010.01364.x. Epub 2010 Dec 22.

PMID:
21332647
19.

Protection by methylproamine of irradiated human keratinocytes correlates with reduction of DNA damage.

Lobachevsky PN, Vasireddy RS, Broadhurst S, Sprung CN, Karagiannis TC, Smith AJ, Radford IR, McKay MJ, Martin RF.

Int J Radiat Biol. 2011 Mar;87(3):274-83. doi: 10.3109/09553002.2011.530333. Epub 2010 Nov 19.

PMID:
21087168
20.

Detailed analysis of DNA repair and senescence marker kinetics over the life span of a human fibroblast cell line.

Endt H, Sprung CN, Keller U, Gaipl U, Fietkau R, Distel LV.

J Gerontol A Biol Sci Med Sci. 2011 Apr;66(4):367-75. doi: 10.1093/gerona/glq197. Epub 2010 Nov 15.

PMID:
21081476
21.

Methylproamine protects against ionizing radiation by preventing DNA double-strand breaks.

Sprung CN, Vasireddy RS, Karagiannis TC, Loveridge SJ, Martin RF, McKay MJ.

Mutat Res. 2010 Oct 13;692(1-2):49-52. doi: 10.1016/j.mrfmmm.2010.08.005. Epub 2010 Aug 21.

PMID:
20732333
22.

Low levels of ATM in breast cancer patients with clinical radiosensitivity.

Fang Z, Kozlov S, McKay MJ, Woods R, Birrell G, Sprung CN, Murrell DF, Wangoo K, Teng L, Kearsley JH, Lavin MF, Graham PH, Clarke RA.

Genome Integr. 2010 Jun 24;1(1):9. doi: 10.1186/2041-9414-1-9.

23.

H2AX phosphorylation screen of cells from radiosensitive cancer patients reveals a novel DNA double-strand break repair cellular phenotype.

Vasireddy RS, Sprung CN, Cempaka NL, Chao M, McKay MJ.

Br J Cancer. 2010 May 11;102(10):1511-8. doi: 10.1038/sj.bjc.6605666.

24.

Unexpectedly severe acute radiotherapy side effects are associated with single nucleotide polymorphisms of the melanocortin-1 receptor.

Fogarty GB, Muddle R, Sprung CN, Chen W, Duffy D, Sturm RA, McKay MJ.

Int J Radiat Oncol Biol Phys. 2010 Aug 1;77(5):1486-92. doi: 10.1016/j.ijrobp.2009.07.1690. Epub 2009 Nov 24.

PMID:
19932942
25.

Hyperthermia and irradiation of head and neck squamous cancer cells causes migratory profile changes of tumour infiltrating lymphocytes.

Schmidtner J, Distel LV, Ott OJ, Nkenke E, Sprung CN, Fietkau R, Lubgan D.

Int J Hyperthermia. 2009 Aug;25(5):347-54. doi: 10.1080/02656730902852677.

PMID:
19479600
26.

Telomere length in lymphoblast cell lines derived from clinically radiosensitive cancer patients.

Sprung CN, Davey DS, Withana NP, Distel LV, McKay MJ.

Cancer Biol Ther. 2008 May;7(5):638-44. Epub 2008 May 20.

PMID:
18364569
27.
28.

Uncoupling of telomere length and radiosensitivity in mouse lymphoma cell lines of similar genetic background.

Sprung CN, Davey DS, Goh SK, Radford IR, McKay MJ.

Int J Radiat Biol. 2007 Aug;83(8):515-21.

PMID:
17613124
29.

Time and dose-dependent activation of p53 serine 15 phosphorylation among cell lines with different radiation sensitivity.

Wittlinger M, Grabenbauer GG, Sprung CN, Sauer R, Distel LV.

Int J Radiat Biol. 2007 Apr;83(4):245-57.

PMID:
17575952
30.

Potential for the G2/M arrest assay to predict patient susceptibility to severe reactions following radiotherapy.

Perez A, Grabenbauer GG, Sprung CN, Sauer R, Distel LV.

Strahlenther Onkol. 2007 Feb;183(2):99-106.

PMID:
17294115
31.

Individual differences in chromosomal aberrations after in vitro irradiation of cells from healthy individuals, cancer and cancer susceptibility syndrome patients.

Distel LV, Neubauer S, Keller U, Sprung CN, Sauer R, Grabenbauer GG.

Radiother Oncol. 2006 Dec;81(3):257-63. Epub 2006 Nov 20.

PMID:
17113667
32.

Prediction of BRCA1 and BRCA2 mutation status using post-irradiation assays of lymphoblastoid cell lines is compromised by inter-cell-line phenotypic variability.

Lovelock PK, Wong EM, Sprung CN, Marsh A, Hobson K, French JD, Southey M, Sculley T, Pandeya N, Brown MA, Chenevix-Trench G, Spurdle AB, McKay MJ; kConFab Investigators.

Breast Cancer Res Treat. 2007 Sep;104(3):257-66. Epub 2006 Oct 25.

PMID:
17063265
33.

Breakpoint locations within chromosomes 1, 2, and 4 of patients with increased radiosensitivity.

Schilling S, Keller U, Sprung CN, Weise A, Grabenbauer GG, Sauer R, Distel L.

Cancer Genet Cytogenet. 2006 Jul 1;168(1):1-10.

PMID:
16772115
34.

Inter-relation of apoptosis and DNA double-strand breaks in patients with multiple primary cancers.

Kaminski BC, Grabenbauer GG, Sprung CN, Sauer R, Distel LV.

Eur J Cancer Prev. 2006 Jun;15(3):274-82.

PMID:
16679873
35.

Telomere position effect and silencing of transgenes near telomeres in the mouse.

Pedram M, Sprung CN, Gao Q, Lo AW, Reynolds GE, Murnane JP.

Mol Cell Biol. 2006 Mar;26(5):1865-78.

36.

Chromosomal radiosensitivity in two cell lineages derived from clinically radiosensitive cancer patients.

Sprung CN, Chao M, Leong T, McKay MJ.

Clin Cancer Res. 2005 Sep 1;11(17):6352-8.

37.

Individual radiosensitivity does not correlate with radiation-induced apoptosis in lymphoblastoid cell lines or CD3+ lymphocytes.

Wistop A, Keller U, Sprung CN, Grabenbauer GG, Sauer R, Distel LV.

Strahlenther Onkol. 2005 May;181(5):326-35.

PMID:
15900430
38.

Cytogenetic instability in young patients with multiple primary cancers.

Keller U, Grabenbauer G, Kuechler A, Sprung CN, Müller E, Sauer R, Distel L.

Cancer Genet Cytogenet. 2005 Feb;157(1):25-32.

PMID:
15676143
39.

Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells.

Lo AW, Sprung CN, Fouladi B, Pedram M, Sabatier L, Ricoul M, Reynolds GE, Murnane JP.

Mol Cell Biol. 2002 Jul;22(13):4836-50.

41.

The influence of interstitial telomeric sequences on chromosome instability in human cells.

Desmaze C, Alberti C, Martins L, Pottier G, Sprung CN, Murnane JP, Sabatier L.

Cytogenet Cell Genet. 1999;86(3-4):288-95.

PMID:
10575228
42.

Telomere instability in a human cancer cell line.

Sprung CN, Afshar G, Chavez EA, Lansdorp P, Sabatier L, Murnane JP.

Mutat Res. 1999 Oct 19;429(2):209-23.

PMID:
10526206
43.

Chromosome healing in mouse embryonic stem cells.

Sprung CN, Reynolds GE, Jasin M, Murnane JP.

Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):6781-6.

44.

Telomere dynamics in a human cancer cell line.

Sprung CN, Sabatier L, Murnane JP.

Exp Cell Res. 1999 Feb 25;247(1):29-37.

PMID:
10047445
45.

Normal telomere maintenance in immortal ataxia telangiectasia cell lines.

Sprung CN, Bryan TM, Reddel RR, Murnane JP.

Mutat Res. 1997 Oct 6;379(2):177-84.

PMID:
9357546
46.

Effect of telomere length on telomeric gene expression.

Sprung CN, Sabatier L, Murnane JP.

Nucleic Acids Res. 1996 Nov 1;24(21):4336-40.

48.

Promoter independent down-regulation of the firefly luciferase gene by T3 and T3 receptor in CV1 cells.

Tillman JB, Crone DE, Kim HS, Sprung CN, Spindler SR.

Mol Cell Endocrinol. 1993 Sep;95(1-2):101-9.

PMID:
8243799
49.

Positive and negative thyroid hormone response elements are composed of strong and weak half-sites 10 nucleotides in length.

Kim HS, Crone DE, Sprung CN, Tillman JB, Force WR, Crew MD, Mote PL, Spindler SR.

Mol Endocrinol. 1992 Sep;6(9):1489-501.

PMID:
1435790
50.

Invasion of the human albumin-alpha-fetoprotein gene family by Alu, Kpn, and two novel repetitive DNA elements.

Ruffner DE, Sprung CN, Minghetti PP, Gibbs PE, Dugaiczyk A.

Mol Biol Evol. 1987 Jan;4(1):1-9.

PMID:
2451775

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