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Items: 9


Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals.

Gentsch GE, Spruce T, Owens NDL, Smith JC.

Nat Commun. 2019 Sep 19;10(1):4269. doi: 10.1038/s41467-019-12263-w.


The Innate Immune Response of Frog Embryos to Antisense Morpholino Oligomers Depends on Developmental Stage, GC Content and Dose.

Gentsch GE, Spruce T, Owens NDL, Monteiro RS, Smith JC.

Dev Cell. 2019 May 20;49(4):506-507. doi: 10.1016/j.devcel.2019.05.004. No abstract available.


Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus.

Gentsch GE, Spruce T, Monteiro RS, Owens NDL, Martin SR, Smith JC.

Dev Cell. 2018 Mar 12;44(5):597-610.e10. doi: 10.1016/j.devcel.2018.01.022. Epub 2018 Feb 22.


MicroRNAs control the apoptotic threshold in primed pluripotent stem cells through regulation of BIM.

Pernaute B, Spruce T, Smith KM, Sánchez-Nieto JM, Manzanares M, Cobb B, Rodríguez TA.

Genes Dev. 2014 Sep 1;28(17):1873-8. doi: 10.1101/gad.245621.114.


MiRNA-mediated regulation of cell signaling and homeostasis in the early mouse embryo.

Pernaute B, Spruce T, Rodriguez TA, Manzanares M.

Cell Cycle. 2011 Feb 15;10(4):584-91. Epub 2011 Feb 15.


An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo.

Spruce T, Pernaute B, Di-Gregorio A, Cobb BS, Merkenschlager M, Manzanares M, Rodriguez TA.

Dev Cell. 2010 Aug 17;19(2):207-19. doi: 10.1016/j.devcel.2010.07.014.


A MicroRNA targeting dicer for metastasis control.

Martello G, Rosato A, Ferrari F, Manfrin A, Cordenonsi M, Dupont S, Enzo E, Guzzardo V, Rondina M, Spruce T, Parenti AR, Daidone MG, Bicciato S, Piccolo S.

Cell. 2010 Jun 25;141(7):1195-207. doi: 10.1016/j.cell.2010.05.017.


Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo.

Santos J, Pereira CF, Di-Gregorio A, Spruce T, Alder O, Rodriguez T, Azuara V, Merkenschlager M, Fisher AG.

Epigenetics Chromatin. 2010 Jan 12;3:1. doi: 10.1186/1756-8935-3-1.


Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a.

Nesterova TB, Popova BC, Cobb BS, Norton S, Senner CE, Tang YA, Spruce T, Rodriguez TA, Sado T, Merkenschlager M, Brockdorff N.

Epigenetics Chromatin. 2008 Oct 27;1(1):2. doi: 10.1186/1756-8935-1-2.

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