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Items: 24

1.

PIKfyve Deficiency in Myeloid Cells Impairs Lysosomal Homeostasis in Macrophages and Promotes Systemic Inflammation in Mice.

Min SH, Suzuki A, Weaver L, Guzman J, Chung Y, Jin H, Gonzalez F, Trasorras C, Zhao L, Spruce LA, Seeholzer SH, Behrens EM, Abrams CS.

Mol Cell Biol. 2019 Oct 11;39(21). pii: e00158-19. doi: 10.1128/MCB.00158-19. Print 2019 Nov 1.

PMID:
31427458
2.

The E3 ubiquitin ligase Itch restricts antigen-driven B cell responses.

Moser EK, Roof J, Dybas JM, Spruce LA, Seeholzer SH, Cancro MP, Oliver PM.

J Exp Med. 2019 Sep 2;216(9):2170-2183. doi: 10.1084/jem.20181953. Epub 2019 Jul 16.

PMID:
31311822
3.

SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation.

Kim ET, Roche KL, Kulej K, Spruce LA, Seeholzer SH, Coen DM, Diaz-Griffero F, Murphy EA, Weitzman MD.

Cell Rep. 2019 Jul 9;28(2):434-448.e6. doi: 10.1016/j.celrep.2019.06.027.

4.

Integrative proteomics reveals an increase in non-degradative ubiquitylation in activated CD4+ T cells.

Dybas JM, O'Leary CE, Ding H, Spruce LA, Seeholzer SH, Oliver PM.

Nat Immunol. 2019 Jun;20(6):747-755. doi: 10.1038/s41590-019-0381-6. Epub 2019 May 6.

PMID:
31061531
5.

Sustained release of endothelial progenitor cell-derived extracellular vesicles from shear-thinning hydrogels improves angiogenesis and promotes function after myocardial infarction.

Chen CW, Wang LL, Zaman S, Gordon J, Arisi MF, Venkataraman CM, Chung JJ, Hung G, Gaffey AC, Spruce LA, Fazelinia H, Gorman RC, Seeholzer SH, Burdick JA, Atluri P.

Cardiovasc Res. 2018 Jun 1;114(7):1029-1040. doi: 10.1093/cvr/cvy067.

6.

Identifying Host Factors Associated with DNA Replicated During Virus Infection.

Reyes ED, Kulej K, Pancholi NJ, Akhtar LN, Avgousti DC, Kim ET, Bricker DK, Spruce LA, Koniski SA, Seeholzer SH, Isaacs SN, Garcia BA, Weitzman MD.

Mol Cell Proteomics. 2017 Dec;16(12):2079-2097. doi: 10.1074/mcp.M117.067116. Epub 2017 Oct 2.

7.

The Neuroprotective Marine Compound Psammaplysene A Binds the RNA-Binding Protein HNRNPK.

Boccitto M, Lee N, Sakamoto S, Spruce LA, Handa H, Clardy J, Seeholzer SH, Kalb RG.

Mar Drugs. 2017 Aug 7;15(8). pii: E246. doi: 10.3390/md15080246.

8.

Improved surfaceome coverage with a label-free nonaffinity-purified workflow.

Glisovic-Aplenc T, Gill S, Spruce LA, Smith IR, Fazelinia H, Shestova O, Ding H, Tasian SK, Aplenc R, Seeholzer SH.

Proteomics. 2017 Apr;17(7). doi: 10.1002/pmic.201600344. Epub 2017 Mar 6.

9.

Neutrophils promote alveolar epithelial regeneration by enhancing type II pneumocyte proliferation in a model of acid-induced acute lung injury.

Paris AJ, Liu Y, Mei J, Dai N, Guo L, Spruce LA, Hudock KM, Brenner JS, Zacharias WJ, Mei HD, Slamowitz AR, Bhamidipati K, Beers MF, Seeholzer SH, Morrisey EE, Worthen GS.

Am J Physiol Lung Cell Mol Physiol. 2016 Dec 1;311(6):L1062-L1075. doi: 10.1152/ajplung.00327.2016. Epub 2016 Sep 30.

10.

Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells.

O'Leary CE, Riling CR, Spruce LA, Ding H, Kumar S, Deng G, Liu Y, Seeholzer SH, Oliver PM.

Nat Commun. 2016 Apr 18;7:11226. doi: 10.1038/ncomms11226.

11.

The Kringle-like Domain Facilitates Post-endoplasmic Reticulum Changes to Premelanosome Protein (PMEL) Oligomerization and Disulfide Bond Configuration and Promotes Amyloid Formation.

Ho T, Watt B, Spruce LA, Seeholzer SH, Marks MS.

J Biol Chem. 2016 Feb 12;291(7):3595-612. doi: 10.1074/jbc.M115.692442. Epub 2015 Dec 22.

12.

Unconventional N-Linked Glycosylation Promotes Trimeric Autotransporter Function in Kingella kingae and Aggregatibacter aphrophilus.

Rempe KA, Spruce LA, Porsch EA, Seeholzer SH, Nørskov-Lauritsen N, St Geme JW 3rd.

MBio. 2015 Aug 25;6(4). pii: e01206-15. doi: 10.1128/mBio.01206-15.

13.

The diabetes susceptibility gene Clec16a regulates mitophagy.

Soleimanpour SA, Gupta A, Bakay M, Ferrari AM, Groff DN, Fadista J, Spruce LA, Kushner JA, Groop L, Seeholzer SH, Kaufman BA, Hakonarson H, Stoffers DA.

Cell. 2014 Jun 19;157(7):1577-90. doi: 10.1016/j.cell.2014.05.016.

14.

Quaternary arrangement of an active, native group II intron ribonucleoprotein complex revealed by small-angle X-ray scattering.

Gupta K, Contreras LM, Smith D, Qu G, Huang T, Spruce LA, Seeholzer SH, Belfort M, Van Duyne GD.

Nucleic Acids Res. 2014 Apr;42(8):5347-60. doi: 10.1093/nar/gku140. Epub 2014 Feb 24.

15.

Site specific identification of endogenous S-nitrosocysteine proteomes.

Doulias PT, Tenopoulou M, Raju K, Spruce LA, Seeholzer SH, Ischiropoulos H.

J Proteomics. 2013 Oct 30;92:195-203. doi: 10.1016/j.jprot.2013.05.033. Epub 2013 Jun 5.

16.

The HtrA protease from Streptococcus pneumoniae digests both denatured proteins and the competence-stimulating peptide.

Cassone M, Gagne AL, Spruce LA, Seeholzer SH, Sebert ME.

J Biol Chem. 2012 Nov 9;287(46):38449-59. doi: 10.1074/jbc.M112.391482. Epub 2012 Sep 25.

17.

Anti-NMDA receptor encephalitis antibody binding is dependent on amino acid identity of a small region within the GluN1 amino terminal domain.

Gleichman AJ, Spruce LA, Dalmau J, Seeholzer SH, Lynch DR.

J Neurosci. 2012 Aug 8;32(32):11082-94. doi: 10.1523/JNEUROSCI.0064-12.2012.

18.

Co-compartmentalization of the astroglial glutamate transporter, GLT-1, with glycolytic enzymes and mitochondria.

Genda EN, Jackson JG, Sheldon AL, Locke SF, Greco TM, O'Donnell JC, Spruce LA, Xiao R, Guo W, Putt M, Seeholzer S, Ischiropoulos H, Robinson MB.

J Neurosci. 2011 Dec 14;31(50):18275-88. doi: 10.1523/JNEUROSCI.3305-11.2011.

19.

Design and NMR characterization of active analogues of compstatin containing non-natural amino acids.

Mallik B, Katragadda M, Spruce LA, Carafides C, Tsokos CG, Morikis D, Lambris JD.

J Med Chem. 2005 Jan 13;48(1):274-86.

PMID:
15634022
20.

CiC3-1a-mediated chemotaxis in the deuterostome invertebrate Ciona intestinalis (Urochordata).

Pinto MR, Chinnici CM, Kimura Y, Melillo D, Marino R, Spruce LA, De Santis R, Parrinello N, Lambris JD.

J Immunol. 2003 Nov 15;171(10):5521-8.

21.

The proinflammatory mediators C3a and C5a are essential for liver regeneration.

Strey CW, Markiewski M, Mastellos D, Tudoran R, Spruce LA, Greenbaum LE, Lambris JD.

J Exp Med. 2003 Sep 15;198(6):913-23.

22.

Studies of structure-activity relations of complement inhibitor compstatin.

Soulika AM, Morikis D, Sarrias MR, Roy M, Spruce LA, Sahu A, Lambris JD.

J Immunol. 2003 Aug 15;171(4):1881-90. Erratum in: J Immunol. 2004 Apr 15;172(8):following 5127.

23.

Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1.

Reca R, Mastellos D, Majka M, Marquez L, Ratajczak J, Franchini S, Glodek A, Honczarenko M, Spruce LA, Janowska-Wieczorek A, Lambris JD, Ratajczak MZ.

Blood. 2003 May 15;101(10):3784-93. Epub 2003 Jan 2.

PMID:
12511407
24.

Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry.

Whitbeck JC, Peng C, Lou H, Xu R, Willis SH, Ponce de Leon M, Peng T, Nicola AV, Montgomery RI, Warner MS, Soulika AM, Spruce LA, Moore WT, Lambris JD, Spear PG, Cohen GH, Eisenberg RJ.

J Virol. 1997 Aug;71(8):6083-93.

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