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Items: 14


CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage.

Sun J, Carlson-Stevermer J, Das U, Shen M, Delenclos M, Snead AM, Koo SY, Wang L, Qiao D, Loi J, Petersen AJ, Stockton M, Bhattacharyya A, Jones MV, Zhao X, McLean PJ, Sproul AA, Saha K, Roy S.

Nat Commun. 2019 Jan 3;10(1):53. doi: 10.1038/s41467-018-07971-8.


Alzheimer's disease and the autophagic-lysosomal system.

Chung KM, Hernández N, Sproul AA, Yu WH.

Neurosci Lett. 2019 Apr 1;697:49-58. doi: 10.1016/j.neulet.2018.05.017. Epub 2018 May 18. Review.


Being human: The role of pluripotent stem cells in regenerative medicine and humanizing Alzheimer's disease models.

Sproul AA.

Mol Aspects Med. 2015 Jun-Oct;43-44:54-65. doi: 10.1016/j.mam.2015.06.007. Epub 2015 Jun 19. Review.


Characterization of a subpopulation of developing cortical interneurons from human iPSCs within serum-free embryoid bodies.

Nestor MW, Jacob S, Sun B, Prè D, Sproul AA, Hong SI, Woodard C, Zimmer M, Chinchalongporn V, Arancio O, Noggle SA.

Am J Physiol Cell Physiol. 2015 Feb 1;308(3):C209-19. doi: 10.1152/ajpcell.00263.2014. Epub 2014 Nov 12.


A time course analysis of the electrophysiological properties of neurons differentiated from human induced pluripotent stem cells (iPSCs).

Prè D, Nestor MW, Sproul AA, Jacob S, Koppensteiner P, Chinchalongporn V, Zimmer M, Yamamoto A, Noggle SA, Arancio O.

PLoS One. 2014 Jul 29;9(7):e103418. doi: 10.1371/journal.pone.0103418. eCollection 2014.


Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors.

Sproul AA, Jacob S, Pre D, Kim SH, Nestor MW, Navarro-Sobrino M, Santa-Maria I, Zimmer M, Aubry S, Steele JW, Kahler DJ, Dranovsky A, Arancio O, Crary JF, Gandy S, Noggle SA.

PLoS One. 2014 Jan 8;9(1):e84547. doi: 10.1371/journal.pone.0084547. eCollection 2014.


Generation of iPSC lines from archived non-cryoprotected biobanked dura mater.

Sproul AA, Vensand LB, Dusenberry CR, Jacob S, Vonsattel JP, Paull DJ, Shelanski ML, Crary JF, Noggle SA.

Acta Neuropathol Commun. 2014 Jan 7;2:4. doi: 10.1186/2051-5960-2-4.


Improved methods for reprogramming human dermal fibroblasts using fluorescence activated cell sorting.

Kahler DJ, Ahmad FS, Ritz A, Hua H, Moroziewicz DN, Sproul AA, Dusenberry CR, Shang L, Paull D, Zimmer M, Weiss KA, Egli D, Noggle SA.

PLoS One. 2013;8(3):e59867. doi: 10.1371/journal.pone.0059867. Epub 2013 Mar 29.


Differentiation of serum-free embryoid bodies from human induced pluripotent stem cells into networks.

Nestor MW, Paull D, Jacob S, Sproul AA, Alsaffar A, Campos BA, Noggle SA.

Stem Cell Res. 2013 May;10(3):454-63. doi: 10.1016/j.scr.2013.02.001. Epub 2013 Feb 13.


The sixth annual translational stem cell research conference of the New York Stem Cell Foundation.

Marshall C, Hua H, Shang L, Ding BS, Zito G, de Peppo GM, Wang GK, Douvaras P, Sproul AA, Paull D, Fossati V, Nestor MW, McKeon D, Smith KA, Solomon SL.

Ann N Y Acad Sci. 2012 May;1255:16-29. doi: 10.1111/j.1749-6632.2012.06481.x. Epub 2012 Mar 28.


Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein.

Wilhelm M, Kukekov NV, Schmit TL, Biagas KV, Sproul AA, Gire S, Maes ME, Xu Z, Greene LA.

J Biol Chem. 2012 Jan 13;287(3):2247-56. doi: 10.1074/jbc.M111.269431. Epub 2011 Nov 28.


Cbl negatively regulates JNK activation and cell death.

Sproul AA, Xu Z, Wilhelm M, Gire S, Greene LA.

Cell Res. 2009 Aug;19(8):950-61. doi: 10.1038/cr.2009.74.


Genetic control of manno(fructo)kinase activity in Escherichia coli.

Sproul AA, Lambourne LT, Jean-Jacques D J, Kornberg HL.

Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):15257-9. Epub 2001 Dec 11.


Facilitated diffusion of fructose via the phosphoenolpyruvate/glucose phosphotransferase system of Escherichia coli.

Kornberg HL, Lambourne LT, Sproul AA.

Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1808-12.

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