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Items: 1 to 50 of 88

1.

Synthetic archaeosome vaccines containing triglycosylarchaeols can provide additive and long-lasting immune responses that are enhanced by archaetidylserine.

Sprott GD, Yeung A, Dicaire CJ, Yu SH, Whitfield DM.

Archaea. 2012;2012:513231. doi: 10.1155/2012/513231. Epub 2012 Sep 30.

2.

The olsA gene mediates the synthesis of an ornithine lipid in Pseudomonas aeruginosa during growth under phosphate-limiting conditions, but is not involved in antimicrobial peptide susceptibility.

Lewenza S, Falsafi R, Bains M, Rohs P, Stupak J, Sprott GD, Hancock RE.

FEMS Microbiol Lett. 2011 Jul;320(2):95-102. doi: 10.1111/j.1574-6968.2011.02295.x. Epub 2011 May 11.

3.

Archaeosome adjuvant overcomes tolerance to tumor-associated melanoma antigens inducing protective CD8 T cell responses.

Krishnan L, Deschatelets L, Stark FC, Gurnani K, Sprott GD.

Clin Dev Immunol. 2010;2010:578432. doi: 10.1155/2010/578432. Epub 2011 Jan 18.

4.

Isopranoid- and dipalmitoyl-aminophospholipid adjuvants impact differently on longevity of CTL immune responses.

Dicaire CJ, Yu SH, Whitfield DM, Sprott GD.

J Liposome Res. 2010 Dec;20(4):304-14. doi: 10.3109/08982100903544151. Epub 2010 Feb 11.

PMID:
20148707
5.

Development of new glycosylation methodologies for the synthesis of archaeal-derived glycolipid adjuvants.

Whitfield DM, Yu SH, Dicaire CJ, Sprott GD.

Carbohydr Res. 2010 Jan 26;345(2):214-29. doi: 10.1016/j.carres.2009.10.011. Epub 2009 Nov 6.

PMID:
20004891
6.

Glycosidase-induced fusion of isoprenoid gentiobiosyl lipid membranes at acidic pH.

Sprott GD, Côté JP, Jarrell HC.

Glycobiology. 2009 Mar;19(3):267-76. doi: 10.1093/glycob/cwn129. Epub 2008 Nov 22.

PMID:
19029107
7.

Synthesis of archaeal glycolipid adjuvants-what is the optimum number of sugars?

Whitfield DM, Eichler EE, Sprott GD.

Carbohydr Res. 2008 Sep 22;343(14):2349-60. doi: 10.1016/j.carres.2008.06.021. Epub 2008 Jul 4.

PMID:
18667197
8.

Adjuvant potential of archaeal synthetic glycolipid mimetics critically depends on the glyco head group structure.

Sprott GD, Dicaire CJ, Côté JP, Whitfield DM.

Glycobiology. 2008 Jul;18(7):559-65. doi: 10.1093/glycob/cwn038. Epub 2008 May 1.

PMID:
18450974
9.

Archaeosome adjuvants: immunological capabilities and mechanism(s) of action.

Krishnan L, Sprott GD.

Vaccine. 2008 Apr 16;26(17):2043-55. doi: 10.1016/j.vaccine.2008.02.026. Epub 2008 Feb 27. Review.

PMID:
18343538
10.
12.

Salt tolerance of archaeal extremely halophilic lipid membranes.

Tenchov B, Vescio EM, Sprott GD, Zeidel ML, Mathai JC.

J Biol Chem. 2006 Apr 14;281(15):10016-23. Epub 2006 Feb 16.

13.
16.
17.

Archaeobacterial ether lipid liposomes as vaccine adjuvants.

Sprott GD, Patel GB, Krishnan L.

Methods Enzymol. 2003;373:155-72. No abstract available.

PMID:
14714403
18.

Novel polar lipids of halophilic eubacterium Planococcus H8 and archaeon Haloferax volcanii.

Sprott GD, Larocque S, Cadotte N, Dicaire CJ, McGee M, Brisson JR.

Biochim Biophys Acta. 2003 Sep 22;1633(3):179-88.

PMID:
14499737
20.

Safety of archaeosome adjuvants evaluated in a mouse model.

Patel GB, Omri A, Deschatelets L, Sprott GD.

J Liposome Res. 2002 Nov;12(4):353-72.

PMID:
12519630
21.

Molecular mechanisms of water and solute transport across archaebacterial lipid membranes.

Mathai JC, Sprott GD, Zeidel ML.

J Biol Chem. 2001 Jul 20;276(29):27266-71. Epub 2001 May 23.

23.
25.

Archaeobacterial ether lipid liposomes (archaeosomes) as novel vaccine and drug delivery systems.

Patel GB, Sprott GD.

Crit Rev Biotechnol. 1999;19(4):317-57. Review.

PMID:
10723627
26.
27.

In vitro assessment of archaeosome stability for developing oral delivery systems.

Patel GB, Agnew BJ, Deschatelets L, Fleming LP, Sprott GD.

Int J Pharm. 2000 Jan 20;194(1):39-49.

PMID:
10601683
28.
29.

A structural comparison of the total polar lipids from the human archaea Methanobrevibacter smithii and Methanosphaera stadtmanae and its relevance to the adjuvant activities of their liposomes.

Sprott GD, Brisson J, Dicaire CJ, Pelletier AK, Deschatelets LA, Krishnan L, Patel GB.

Biochim Biophys Acta. 1999 Sep 22;1440(2-3):275-88.

PMID:
10521711
30.
31.

Lateral diffusion of the total polar lipids from Thermoplasma acidophilum in multilamellar liposomes.

Jarrell HC, Zukotynski KA, Sprott GD.

Biochim Biophys Acta. 1998 Mar 2;1369(2):259-66.

32.

Archaeosomes as novel antigen delivery systems.

Sprott GD, Tolson DL, Patel GB.

FEMS Microbiol Lett. 1997 Sep 1;154(1):17-22.

33.

Identification of beta-L-gulose as the sugar moiety of the main polar lipid Thermoplasma acidophilum.

Swain M, Brisson JR, Sprott GD, Cooper FP, Patel GB.

Biochim Biophys Acta. 1997 Mar 10;1345(1):56-64.

PMID:
9084501
34.

Stability of pressure-extruded liposomes made from archaeobacterial ether lipids.

Choquet CG, Patel GB, Beveridge TJ, Sprott GD.

Appl Microbiol Biotechnol. 1994 Nov;42(2-3):375-84.

PMID:
7765779
36.

Natural and Electroporation-Mediated Transformation of Methanococcus voltae Protoplasts.

Patel GB, Nash JH, Agnew BJ, Sprott GD.

Appl Environ Microbiol. 1994 Mar;60(3):903-7.

37.

Metabolic Pathways in Methanococcus jannaschii and Other Methanogenic Bacteria.

Sprott GD, Ekiel I, Patel GB.

Appl Environ Microbiol. 1993 Apr;59(4):1092-8.

38.

Hydroxydiether Lipid Structures in Methanosarcina spp. and Methanococcus voltae.

Sprott GD, Dicaire CJ, Choquet CG, Patel GB, Ekiel I.

Appl Environ Microbiol. 1993 Mar;59(3):912-4.

39.

Freeze-fracture planes of methanogen membranes correlate with the content of tetraether lipids.

Beveridge TJ, Choquet CG, Patel GB, Sprott GD.

J Bacteriol. 1993 Feb;175(4):1191-7.

40.

Formation and Regeneration of Methanococcus voltae Protoplasts.

Patel GB, Choquet CG, Nash JH, Sprott GD.

Appl Environ Microbiol. 1993 Jan;59(1):27-33.

41.

Structures of archaebacterial membrane lipids.

Sprott GD.

J Bioenerg Biomembr. 1992 Dec;24(6):555-66. Review.

PMID:
1459987
42.

Application of time-resolved diffuse reflectance techniques in studies of reaction intermediates in suspensions of Bacillus subtilis.

Berinstain AB, Scaiano JC, Bohne C, Malenfant PR, Sprott GD.

Photochem Photobiol. 1992 Oct;56(4):423-6.

PMID:
1454871
43.

Formation of unilamellar liposomes from total polar lipid extracts of methanogens.

Choquet CG, Patel GB, Beveridge TJ, Sprott GD.

Appl Environ Microbiol. 1992 Sep;58(9):2894-900.

44.
46.

Novel, acid-labile, hydroxydiether lipid cores in methanogenic bacteria.

Sprott GD, Ekiel I, Dicaire C.

J Biol Chem. 1990 Aug 15;265(23):13735-40.

47.

Structures of polar lipids from the thermophilic, deep-sea archaeobacterium Methanococcus jannaschii.

Ferrante G, Richards JC, Sprott GD.

Biochem Cell Biol. 1990 Jan;68(1):274-83.

PMID:
2372322
48.

Structures of minor ether lipids isolated from the aceticlastic methanogen, Methanothrix concilii GP6.

Ferrante G, Brisson JR, Patel GB, Ekiel I, Sprott GD.

J Lipid Res. 1989 Oct;30(10):1601-9.

49.

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