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Items: 35


Chemerin influences endothelin- and serotonin-induced pulmonary artery vasoconstriction in rats.

Hanthazi A, Jespers P, Vegh G, Degroot GN, Springael JY, Lybaert P, Dewachter L, Entee KMC.

Life Sci. 2019 Jun 16:116580. doi: 10.1016/j.lfs.2019.116580. [Epub ahead of print]


The interaction effect between vibrations and temperature simulating truck transport on the flavor stability of beer.

Paternoster A, Jaskula-Goiris B, De Causmaecker B, Vanlanduit S, Springael J, Braet J, De Rouck G, De Cooman L.

J Sci Food Agric. 2019 Mar 30;99(5):2165-2174. doi: 10.1002/jsfa.9409. Epub 2018 Nov 26.


Pericardial Adipose Tissue Regulates Granulopoiesis, Fibrosis, and Cardiac Function After Myocardial Infarction.

Horckmans M, Bianchini M, Santovito D, Megens RTA, Springael JY, Negri I, Vacca M, Di Eusanio M, Moschetta A, Weber C, Duchene J, Steffens S.

Circulation. 2018 Feb 27;137(9):948-960. doi: 10.1161/CIRCULATIONAHA.117.028833. Epub 2017 Nov 22.


Partial Agonist and Biased Signaling Properties of the Synthetic Enantiomers J113863/UCB35625 at Chemokine Receptors CCR2 and CCR5.

Corbisier J, Huszagh A, Galés C, Parmentier M, Springael JY.

J Biol Chem. 2017 Jan 13;292(2):575-584. doi: 10.1074/jbc.M116.757559. Epub 2016 Nov 28.


Signaling Properties of Chemerin Receptors CMKLR1, GPR1 and CCRL2.

De Henau O, Degroot GN, Imbault V, Robert V, De Poorter C, Mcheik S, Galés C, Parmentier M, Springael JY.

PLoS One. 2016 Oct 7;11(10):e0164179. doi: 10.1371/journal.pone.0164179. eCollection 2016.


Identification of a Novel Regulatory Mechanism of Nutrient Transport Controlled by TORC1-Npr1-Amu1/Par32.

Boeckstaens M, Merhi A, Llinares E, Van Vooren P, Springael JY, Wintjens R, Marini AM.

PLoS Genet. 2015 Jul 14;11(7):e1005382. doi: 10.1371/journal.pgen.1005382. eCollection 2015 Jul.


Biased signaling at chemokine receptors.

Corbisier J, Galès C, Huszagh A, Parmentier M, Springael JY.

J Biol Chem. 2015 Apr 10;290(15):9542-54. doi: 10.1074/jbc.M114.596098. Epub 2015 Jan 22.


Consequences of ChemR23 heteromerization with the chemokine receptors CXCR4 and CCR7.

de Poorter C, Baertsoen K, Lannoy V, Parmentier M, Springael JY.

PLoS One. 2013;8(2):e58075. doi: 10.1371/journal.pone.0058075. Epub 2013 Feb 28.


Stroma cell-derived factor-1α signaling enhances calcium transients and beating frequency in rat neonatal cardiomyocytes.

Hadad I, Veithen A, Springael JY, Sotiropoulou PA, Mendes Da Costa A, Miot F, Naeije R, De Deken X, Entee KM.

PLoS One. 2013;8(2):e56007. doi: 10.1371/journal.pone.0056007. Epub 2013 Feb 27.


The chemerin/ChemR23 system does not affect the pro-inflammatory response of mouse and human macrophages ex vivo.

Bondue B, De Henau O, Luangsay S, Devosse T, de Nadaï P, Springael JY, Parmentier M, Vosters O.

PLoS One. 2012;7(6):e40043. doi: 10.1371/journal.pone.0040043. Epub 2012 Jun 29.


Opening the research agenda for selection of hot spots for human biomonitoring research in Belgium: a participatory research project.

Keune H, Morrens B, Croes K, Colles A, Koppen G, Springael J, Loots I, Van Campenhout K, Chovanova H, Schoeters G, Nelen V, Baeyens W, Van Larebeke N.

Environ Health. 2010 Jul 6;9:33. doi: 10.1186/1476-069X-9-33.


Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists.

Sohy D, Yano H, de Nadai P, Urizar E, Guillabert A, Javitch JA, Parmentier M, Springael JY.

J Biol Chem. 2009 Nov 6;284(45):31270-9. doi: 10.1074/jbc.M109.054809. Epub 2009 Sep 15.


Significance of N-terminal proteolysis of CCL14a to activity on the chemokine receptors CCR1 and CCR5 and the human cytomegalovirus-encoded chemokine receptor US28.

Richter R, Casarosa P, Ständker L, Münch J, Springael JY, Nijmeijer S, Forssmann WG, Vischer HF, Vakili J, Detheux M, Parmentier M, Leurs R, Smit MJ.

J Immunol. 2009 Jul 15;183(2):1229-37. doi: 10.4049/jimmunol.0802145. Epub 2009 Jun 24.


Synergy between coproduced CC and CXC chemokines in monocyte chemotaxis through receptor-mediated events.

Gouwy M, Struyf S, Noppen S, Schutyser E, Springael JY, Parmentier M, Proost P, Van Damme J.

Mol Pharmacol. 2008 Aug;74(2):485-95. doi: 10.1124/mol.108.045146. Epub 2008 May 9.


Highly potent HIV inhibition: engineering a key anti-HIV structure from PSC-RANTES into MIP-1 beta/CCL4.

Gaertner H, Lebeau O, Borlat I, Cerini F, Dufour B, Kuenzi G, Melotti A, Fish RJ, Offord R, Springael JY, Parmentier M, Hartley O.

Protein Eng Des Sel. 2008 Feb;21(2):65-72. doi: 10.1093/protein/gzm079. Epub 2008 Jan 4.


The A5 gene of alcelaphine herpesvirus 1 encodes a constitutively active G-protein-coupled receptor that is non-essential for the induction of malignant catarrhal fever in rabbits.

Boudry C, Markine-Goriaynoff N, Delforge C, Springael JY, de Leval L, Drion P, Russell G, Haig DM, Vanderplasschen AF, Dewals B.

J Gen Virol. 2007 Dec;88(Pt 12):3224-33.


Allosteric transinhibition by specific antagonists in CCR2/CXCR4 heterodimers.

Sohy D, Parmentier M, Springael JY.

J Biol Chem. 2007 Oct 12;282(41):30062-9. Epub 2007 Aug 22.


Allosteric properties of G protein-coupled receptor oligomers.

Springael JY, Urizar E, Costagliola S, Vassart G, Parmentier M.

Pharmacol Ther. 2007 Sep;115(3):410-8. Epub 2007 Jun 27. Review.


The activation mechanism of chemokine receptor CCR5 involves common structural changes but a different network of interhelical interactions relative to rhodopsin.

Springael JY, de Poorter C, Deupi X, Van Durme J, Pardo L, Parmentier M.

Cell Signal. 2007 Jul;19(7):1446-56. Epub 2007 Jan 25.


Identification of nonpeptide CCR5 receptor agonists by structure-based virtual screening.

Kellenberger E, Springael JY, Parmentier M, Hachet-Haas M, Galzi JL, Rognan D.

J Med Chem. 2007 Mar 22;50(6):1294-303. Epub 2007 Feb 21.


Human T-cell leukemia virus type-1 Tax oncoprotein regulates G-protein signaling.

Twizere JC, Springael JY, Boxus M, Burny A, Dequiedt F, Dewulf JF, Duchateau J, Portetelle D, Urbain P, Van Lint C, Green PL, Mahieux R, Parmentier M, Willems L, Kettmann R.

Blood. 2007 Feb 1;109(3):1051-60. Epub 2006 Sep 21.


Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers.

Springael JY, Le Minh PN, Urizar E, Costagliola S, Vassart G, Parmentier M.

Mol Pharmacol. 2006 May;69(5):1652-61. Epub 2006 Feb 7.


Dimerization of chemokine receptors and its functional consequences.

Springael JY, Urizar E, Parmentier M.

Cytokine Growth Factor Rev. 2005 Dec;16(6):611-23. Epub 2005 Jun 23. Review.


Evidence for negative binding cooperativity within CCR5-CCR2b heterodimers.

El-Asmar L, Springael JY, Ballet S, Andrieu EU, Vassart G, Parmentier M.

Mol Pharmacol. 2005 Feb;67(2):460-9. Epub 2004 Oct 27.


Glutathione metabolism of Acremonium chrysogenum in relation to cephalosporin C production: is gamma-glutamyltransferase in the center?

Nagy MA, Emri T, Fekete E, Sándor E, Springael JY, Penninckx MJ, Pócsi I.

Folia Microbiol (Praha). 2003;48(2):149-55.


Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation.

Le Poul E, Loison C, Struyf S, Springael JY, Lannoy V, Decobecq ME, Brezillon S, Dupriez V, Vassart G, Van Damme J, Parmentier M, Detheux M.

J Biol Chem. 2003 Jul 11;278(28):25481-9. Epub 2003 Apr 23.


Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3.

Govaerts C, Bondue A, Springael JY, Olivella M, Deupi X, Le Poul E, Wodak SJ, Parmentier M, Pardo L, Blanpain C.

J Biol Chem. 2003 Jan 17;278(3):1892-903. Epub 2002 Oct 30.


Yeast Npi3/Bro1 is involved in ubiquitin-dependent control of permease trafficking.

Springael JY, Nikko E, André B, Marini AM.

FEBS Lett. 2002 Apr 24;517(1-3):103-9.


Cross-talk between ammonium transporters in yeast and interference by the soybean SAT1 protein.

Marini AM, Springael JY, Frommer WB, André B.

Mol Microbiol. 2000 Jan;35(2):378-85.


NH4+-induced down-regulation of the Saccharomyces cerevisiae Gap1p permease involves its ubiquitination with lysine-63-linked chains.

Springael JY, Galan JM, Haguenauer-Tsapis R, André B.

J Cell Sci. 1999 May;112 ( Pt 9):1375-83.


NPl1, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin-protein ligase.

Hein C, Springael JY, Volland C, Haguenauer-Tsapis R, André B.

Mol Microbiol. 1995 Oct;18(1):77-87.


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