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Items: 1 to 50 of 100

1.

2-Ketogluconate Kinase from Cupriavidus necator H16: Purification, Characterization, and Exploration of Its Substrate Specificity.

Sánchez-Moreno I, Trachtmann N, Ilhan S, Hélaine V, Lemaire M, Guérard-Hélaine C, Sprenger GA.

Molecules. 2019 Jun 28;24(13). pii: E2393. doi: 10.3390/molecules24132393.

2.

Alteration of the Route to Menaquinone towards Isochorismate-Derived Metabolites.

Fries A, Mazzaferro LS, Grüning B, Bisel P, Stibal K, Buchholz PCF, Pleiss J, Sprenger GA, Müller M.

Chembiochem. 2019 Jul 1;20(13):1672-1677. doi: 10.1002/cbic.201900050. Epub 2019 May 24.

3.

Metabolic Engineering of Escherichia coli for para-Amino-Phenylethanol and para-Amino-Phenylacetic Acid Biosynthesis.

Mohammadi Nargesi B, Sprenger GA, Youn JW.

Front Bioeng Biotechnol. 2019 Jan 4;6:201. doi: 10.3389/fbioe.2018.00201. eCollection 2018.

4.

Production of p-amino-L-phenylalanine (L-PAPA) from glycerol by metabolic grafting of Escherichia coli.

Mohammadi Nargesi B, Trachtmann N, Sprenger GA, Youn JW.

Microb Cell Fact. 2018 Sep 21;17(1):149. doi: 10.1186/s12934-018-0996-6.

5.

Fed-batch production of l-tryptophan from glycerol using recombinant Escherichia coli.

Tröndle J, Trachtmann N, Sprenger GA, Weuster-Botz D.

Biotechnol Bioeng. 2018 Dec;115(12):2881-2892. doi: 10.1002/bit.26834. Epub 2018 Oct 6.

PMID:
30199091
6.

Extended substrate range of thiamine diphosphate-dependent MenD enzyme by coupling of two C-C-bonding reactions.

Schapfl M, Baier S, Fries A, Ferlaino S, Waltzer S, Müller M, Sprenger GA.

Appl Microbiol Biotechnol. 2018 Oct;102(19):8359-8372. doi: 10.1007/s00253-018-9259-z. Epub 2018 Jul 31.

PMID:
30062480
7.

Phosphoenolpyruvate Transporter Enables Targeted Perturbation During Metabolic Analysis of L-Phenylalanine Production With Escherichia coli.

Tröndle J, Albermann C, Weiner M, Sprenger GA, Weuster-Botz D.

Biotechnol J. 2018 May;13(5):e1700611. doi: 10.1002/biot.201700611. Epub 2017 Dec 28.

PMID:
29220111
8.

Production of human milk oligosaccharides by enzymatic and whole-cell microbial biotransformations.

Sprenger GA, Baumgärtner F, Albermann C.

J Biotechnol. 2017 Sep 20;258:79-91. doi: 10.1016/j.jbiotec.2017.07.030. Epub 2017 Jul 29.

PMID:
28764968
9.

Functional expression of a human GDP-L-fucose transporter in Escherichia coli.

Förster-Fromme K, Schneider S, Sprenger GA, Albermann C.

Biotechnol Lett. 2017 Feb;39(2):219-226. doi: 10.1007/s10529-016-2233-x. Epub 2016 Oct 13.

PMID:
27738779
10.

Novel mode of inhibition by D-tagatose 6-phosphate through a Heyns rearrangement in the active site of transaldolase B variants.

Stellmacher L, Sandalova T, Schneider S, Schneider G, Sprenger GA, Samland AK.

Acta Crystallogr D Struct Biol. 2016 Apr;72(Pt 4):467-76. doi: 10.1107/S2059798316001170. Epub 2016 Mar 24.

PMID:
27050126
11.

Synthesis of fucosylated lacto-N-tetraose using whole-cell biotransformation.

Baumgärtner F, Jurzitza L, Conrad J, Beifuss U, Sprenger GA, Albermann C.

Bioorg Med Chem. 2015 Nov 1;23(21):6799-806. doi: 10.1016/j.bmc.2015.10.005. Epub 2015 Oct 9.

PMID:
26481658
12.

Galactose-limited fed-batch cultivation of Escherichia coli for the production of lacto-N-tetraose.

Baumgärtner F, Sprenger GA, Albermann C.

Enzyme Microb Technol. 2015 Jul-Aug;75-76:37-43. doi: 10.1016/j.enzmictec.2015.04.009. Epub 2015 May 2.

PMID:
26047914
13.

Perturbation Experiments: Approaches for Metabolic Pathway Analysis in Bioreactors.

Weiner M, Tröndle J, Albermann C, Sprenger GA, Weuster-Botz D.

Adv Biochem Eng Biotechnol. 2016;152:91-136. doi: 10.1007/10_2015_326.

PMID:
25981857
14.

Parallelized small-scale production of uniformly (13)C-labeled cell extract for quantitative metabolome analysis.

Weiner M, Tröndle J, Schmideder A, Albermann C, Binder K, Sprenger GA, Weuster-Botz D.

Anal Biochem. 2015 Jun 1;478:134-40. doi: 10.1016/j.ab.2015.03.008. Epub 2015 Mar 12.

PMID:
25772305
15.

Utilization of organophosphate:phosphate antiporter for isotope-labeling experiments in E. coli.

Albermann C, Weiner M, Tröndle J, Weuster-Botz D, Sprenger GA.

FEMS Microbiol Lett. 2014 Dec;361(1):52-61. Epub 2015 Jan 8.

16.

Synthesis of the human milk oligosaccharide lacto-N-tetraose in metabolically engineered, plasmid-free E. coli.

Baumgärtner F, Conrad J, Sprenger GA, Albermann C.

Chembiochem. 2014 Sep 5;15(13):1896-900. doi: 10.1002/cbic.201402070. Epub 2014 Jul 17.

PMID:
25044565
17.

Improvement of L-phenylalanine production from glycerol by recombinant Escherichia coli strains: the role of extra copies of glpK, glpX, and tktA genes.

Gottlieb K, Albermann C, Sprenger GA.

Microb Cell Fact. 2014 Jul 11;13(1):96. doi: 10.1186/s12934-014-0096-1.

18.

Carbon storage in recombinant Escherichia coli during growth on glycerol and lactic acid.

Weiner M, Tröndle J, Albermann C, Sprenger GA, Weuster-Botz D.

Biotechnol Bioeng. 2014 Dec;111(12):2508-19. doi: 10.1002/bit.25306. Epub 2014 Jul 29.

PMID:
24902947
19.

Improvement of constraint-based flux estimation during L-phenylalanine production with Escherichia coli using targeted knock-out mutants.

Weiner M, Tröndle J, Albermann C, Sprenger GA, Weuster-Botz D.

Biotechnol Bioeng. 2014 Jul;111(7):1406-16. doi: 10.1002/bit.25195. Epub 2014 Feb 12.

PMID:
24449451
20.

Systems metabolic engineering of Escherichia coli for production of the antitumor drugs violacein and deoxyviolacein.

Rodrigues AL, Trachtmann N, Becker J, Lohanatha AF, Blotenberg J, Bolten CJ, Korneli C, de Souza Lima AO, Porto LM, Sprenger GA, Wittmann C.

Metab Eng. 2013 Nov;20:29-41. doi: 10.1016/j.ymben.2013.08.004. Epub 2013 Aug 29.

PMID:
23994489
21.

Construction of Escherichia coli strains with chromosomally integrated expression cassettes for the synthesis of 2'-fucosyllactose.

Baumgärtner F, Seitz L, Sprenger GA, Albermann C.

Microb Cell Fact. 2013 May 1;12:40. doi: 10.1186/1475-2859-12-40.

22.

CC bond formation using ThDP-dependent lyases.

Müller M, Sprenger GA, Pohl M.

Curr Opin Chem Biol. 2013 Apr;17(2):261-70. doi: 10.1016/j.cbpa.2013.02.017. Epub 2013 Mar 20. Review.

PMID:
23523314
23.

TCA cycle involved enzymes SucA and Kgd, as well as MenD: efficient biocatalysts for asymmetric C-C bond formation.

Beigi M, Waltzer S, Fries A, Eggeling L, Sprenger GA, Müller M.

Org Lett. 2013 Feb 1;15(3):452-5. doi: 10.1021/ol3031186. Epub 2013 Jan 14.

PMID:
23317369
24.

Towards the in vivo production of tocotrienol compounds: engineering of a plasmid-free Escherichia coli strain for the heterologous synthesis of 2-methyl-6-geranylgeranyl-benzoquinol.

Ghanegaonkar S, Conrad J, Beifuss U, Sprenger GA, Albermann C.

J Biotechnol. 2012 Dec 15;164(2):238-47. doi: 10.1016/j.jbiotec.2012.08.010. Epub 2012 Sep 7.

PMID:
22982400
25.

Conservation of structure and mechanism within the transaldolase enzyme family.

Samland AK, Baier S, Schürmann M, Inoue T, Huf S, Schneider G, Sprenger GA, Sandalova T.

FEBS J. 2012 Mar;279(5):766-78. doi: 10.1111/j.1742-4658.2011.08467.x. Epub 2012 Jan 30.

26.

Diversity-oriented production of metabolites derived from chorismate and their use in organic synthesis.

Bongaerts J, Esser S, Lorbach V, Al-Momani L, Müller MA, Franke D, Grondal C, Kurutsch A, Bujnicki R, Takors R, Raeven L, Wubbolts M, Bovenberg R, Nieger M, Schürmann M, Trachtmann N, Kozak S, Sprenger GA, Müller M.

Angew Chem Int Ed Engl. 2011 Aug 16;50(34):7781-6. doi: 10.1002/anie.201103261. Epub 2011 Jul 7. No abstract available.

PMID:
21739551
27.

The transaldolase family: new synthetic opportunities from an ancient enzyme scaffold.

Samland AK, Rale M, Sprenger GA, Fessner WD.

Chembiochem. 2011 Jul 4;12(10):1454-74. doi: 10.1002/cbic.201100072. Epub 2011 May 13. Review.

PMID:
21574238
28.

Broadening deoxysugar glycodiversity: natural and engineered transaldolases unlock a complementary substrate space.

Rale M, Schneider S, Sprenger GA, Samland AK, Fessner WD.

Chemistry. 2011 Feb 25;17(9):2623-32. doi: 10.1002/chem.201002942. Epub 2011 Feb 2.

PMID:
21290439
29.

Redesigning the active site of transaldolase TalB from Escherichia coli: new variants with improved affinity towards nonphosphorylated substrates.

Schneider S, Gutiérrez M, Sandalova T, Schneider G, Clapés P, Sprenger GA, Samland AK.

Chembiochem. 2010 Mar 22;11(5):681-90. doi: 10.1002/cbic.200900720.

PMID:
20148428
30.

Recent progress in stereoselective synthesis with aldolases.

Clapés P, Fessner WD, Sprenger GA, Samland AK.

Curr Opin Chem Biol. 2010 Apr;14(2):154-67. doi: 10.1016/j.cbpa.2009.11.029. Epub 2010 Jan 12. Review.

PMID:
20071212
31.

A simple and reliable method to conduct and monitor expression cassette integration into the Escherichia coli chromosome.

Albermann C, Trachtmann N, Sprenger GA.

Biotechnol J. 2010 Jan;5(1):32-8. doi: 10.1002/biot.200900193.

PMID:
19946879
32.

Transaldolase: from biochemistry to human disease.

Samland AK, Sprenger GA.

Int J Biochem Cell Biol. 2009 Jul;41(7):1482-94. doi: 10.1016/j.biocel.2009.02.001. Epub 2009 Feb 11. Review.

PMID:
19401148
33.

Biosynthesis of the vitamin E compound delta-tocotrienol in recombinant Escherichia coli cells.

Albermann C, Ghanegaonkar S, Lemuth K, Vallon T, Reuss M, Armbruster W, Sprenger GA.

Chembiochem. 2008 Oct 13;9(15):2524-33. doi: 10.1002/cbic.200800242.

PMID:
18810749
34.

Replacement of a phenylalanine by a tyrosine in the active site confers fructose-6-phosphate aldolase activity to the transaldolase of Escherichia coli and human origin.

Schneider S, Sandalova T, Schneider G, Sprenger GA, Samland AK.

J Biol Chem. 2008 Oct 31;283(44):30064-72. doi: 10.1074/jbc.M803184200. Epub 2008 Aug 7.

35.

MJ0400 from Methanocaldococcus jannaschii exhibits fructose-1,6-bisphosphate aldolase activity.

Samland AK, Wang M, Sprenger GA.

FEMS Microbiol Lett. 2008 Apr;281(1):36-41. doi: 10.1111/j.1574-6968.2008.01079.x.

36.
37.

Escherichia coli twin arginine (Tat) mutant translocases possessing relaxed signal peptide recognition specificities.

Kreutzenbeck P, Kröger C, Lausberg F, Blaudeck N, Sprenger GA, Freudl R.

J Biol Chem. 2007 Mar 16;282(11):7903-11. Epub 2007 Jan 16.

38.

Fructose-6-phosphate aldolase in organic synthesis: preparation of D-fagomine, N-alkylated derivatives, and preliminary biological assays.

Castillo JA, Calveras J, Casas J, Mitjans M, Vinardell MP, Parella T, Inoue T, Sprenger GA, Joglar J, Clapés P.

Org Lett. 2006 Dec 21;8(26):6067-70.

PMID:
17165931
39.

Microbial aldolases as C-C bonding enzymes--unknown treasures and new developments.

Samland AK, Sprenger GA.

Appl Microbiol Biotechnol. 2006 Jul;71(3):253-64. Epub 2006 Apr 14. Review.

PMID:
16614860
40.

Stimulation, monitoring, and analysis of pathway dynamics by metabolic profiling in the aromatic amino acid pathway.

Oldiges M, Kunze M, Degenring D, Sprenger GA, Takors R.

Biotechnol Prog. 2004 Nov-Dec;20(6):1623-33.

PMID:
15575692
41.

Isolation and characterization of bifunctional Escherichia coli TatA mutant proteins that allow efficient tat-dependent protein translocation in the absence of TatB.

Blaudeck N, Kreutzenbeck P, Müller M, Sprenger GA, Freudl R.

J Biol Chem. 2005 Feb 4;280(5):3426-32. Epub 2004 Nov 22.

42.

A new perspective on thiamine catalysis.

Pohl M, Sprenger GA, Müller M.

Curr Opin Biotechnol. 2004 Aug;15(4):335-42. Review.

PMID:
15296931
43.

Fully integrated L-phenylalanine separation and concentration using reactive-extraction with liquid-liquid centrifuges in a fed-batch process with E. coli.

Rüffer N, Heidersdorf U, Kretzers I, Sprenger GA, Raeven L, Takors R.

Bioprocess Biosyst Eng. 2004 Jul;26(4):239-48. Epub 2004 Mar 26.

PMID:
15045576
44.

Modeling of reaction kinetics for reactor selection in the case of L-erythrulose synthesis.

Vasic-Racki D, Bongs J, Schörken U, Sprenger GA, Liese A.

Bioprocess Biosyst Eng. 2003 Mar;25(5):285-90. Epub 2003 Jan 30.

PMID:
14505172
45.

(S,S)-2,3-Dihydroxy-2,3-dihydrobenzoic acid: microbial access with engineered cells of Escherichia coli and application as starting material in natural-product synthesis.

Franke D, Lorbach V, Esser S, Dose C, Sprenger GA, Halfar M, Thömmes J, Müller R, Takors R, Müller M.

Chemistry. 2003 Sep 5;9(17):4188-96.

PMID:
12953204
46.

Easy access to (R,R)-3,4-dihydroxy-3,4-dihydrobenzoic acid with engineered strains of Escherichia coli.

Franke D, Sprenger GA, Müller M.

Chembiochem. 2003 Aug 4;4(8):775-7. No abstract available.

PMID:
12898630
47.
48.

Fluorogenic stereochemical probes for transaldolases.

González-García E, Helaine V, Klein G, Schuermann M, Sprenger GA, Fessner WD, Reymond JL.

Chemistry. 2003 Feb 17;9(4):893-9.

PMID:
12584704
49.
50.

Conformational changes during the catalytic cycle of gluconate kinase as revealed by X-ray crystallography.

Kraft L, Sprenger GA, Lindqvist Y.

J Mol Biol. 2002 May 10;318(4):1057-69.

PMID:
12054802

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