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Items: 1 to 50 of 363

1.

Concentrative Transport of Antifolates Mediated by the Proton-Coupled Folate Transporter (SLC46A1); Augmentation by a HEPES Buffer.

Zhao R, Najmi M, Aluri S, Spray DC, Goldman ID.

Mol Pharmacol. 2018 Mar;93(3):208-215. doi: 10.1124/mol.117.110445. Epub 2018 Jan 11.

PMID:
29326243
2.

Functional genomic fabrics are remodeled in a mouse model of Chagasic cardiomyopathy and restored following cell therapy.

Iacobas DA, Iacobas S, Tanowitz HB, Campos de Carvalho A, Spray DC.

Microbes Infect. 2018 Mar;20(3):185-195. doi: 10.1016/j.micinf.2017.11.003. Epub 2017 Nov 20.

PMID:
29158000
3.

Potential role for a specialized β3 integrin-based structure on osteocyte processes in bone mechanosensation.

Cabahug-Zuckerman P, Stout RF Jr, Majeska RJ, Thi MM, Spray DC, Weinbaum S, Schaffler MB.

J Orthop Res. 2018 Feb;36(2):642-652. doi: 10.1002/jor.23792. Epub 2017 Nov 28.

PMID:
29087614
4.

Osteocyte calcium signals encode strain magnitude and loading frequency in vivo.

Lewis KJ, Frikha-Benayed D, Louie J, Stephen S, Spray DC, Thi MM, Seref-Ferlengez Z, Majeska RJ, Weinbaum S, Schaffler MB.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11775-11780. doi: 10.1073/pnas.1707863114. Epub 2017 Oct 19.

5.

Cysteine residues in the cytoplasmic carboxy terminus of connexins dictate gap junction plaque stability.

Stout RF Jr, Spray DC.

Mol Biol Cell. 2017 Oct 15;28(21):2757-2764. doi: 10.1091/mbc.E17-03-0206. Epub 2017 Aug 23.

6.

Gap junctions, pannexins and pain.

Spray DC, Hanani M.

Neurosci Lett. 2017 Jun 22. pii: S0304-3940(17)30515-3. doi: 10.1016/j.neulet.2017.06.035. [Epub ahead of print] Review.

PMID:
28647288
7.

Structural and Functional Consequences of Connexin 36 (Cx36) Interaction with Calmodulin.

Siu RC, Smirnova E, Brown CA, Zoidl C, Spray DC, Donaldson LW, Zoidl G.

Front Mol Neurosci. 2016 Nov 18;9:120. eCollection 2016.

8.

Glial pannexin1 contributes to tactile hypersensitivity in a mouse model of orofacial pain.

Hanstein R, Hanani M, Scemes E, Spray DC.

Sci Rep. 2016 Dec 2;6:38266. doi: 10.1038/srep38266.

9.

Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals.

Zhu Y, Gao Y, Tao C, Shao M, Zhao S, Huang W, Yao T, Johnson JA, Liu T, Cypess AM, Gupta O, Holland WL, Gupta RK, Spray DC, Tanowitz HB, Cao L, Lynes MD, Tseng YH, Elmquist JK, Williams KW, Lin HV, Scherer PE.

Cell Metab. 2016 Sep 13;24(3):420-433. doi: 10.1016/j.cmet.2016.08.005.

10.

Coupled Activation of Primary Sensory Neurons Contributes to Chronic Pain.

Kim YS, Anderson M, Park K, Zheng Q, Agarwal A, Gong C, Saijilafu, Young L, He S, LaVinka PC, Zhou F, Bergles D, Hanani M, Guan Y, Spray DC, Dong X.

Neuron. 2016 Sep 7;91(5):1085-1096. doi: 10.1016/j.neuron.2016.07.044. Epub 2016 Aug 25.

11.

P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes.

Seref-Ferlengez Z, Maung S, Schaffler MB, Spray DC, Suadicani SO, Thi MM.

PLoS One. 2016 May 9;11(5):e0155107. doi: 10.1371/journal.pone.0155107. eCollection 2016.

12.

Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria.

Freeman BD, Martins YC, Akide-Ndunge OB, Bruno FP, Wang H, Tanowitz HB, Spray DC, Desruisseaux MS.

PLoS Pathog. 2016 Mar 31;12(3):e1005477. doi: 10.1371/journal.ppat.1005477. eCollection 2016 Mar.

13.

Effect of mesenchymal stem cells and mouse embryonic fibroblasts on the development of preimplantation mouse embryos.

Jasmin, Peters VM, Spray DC, Mendez-Otero R.

In Vitro Cell Dev Biol Anim. 2016 Apr;52(4):497-506. doi: 10.1007/s11626-015-9997-5. Epub 2016 Jan 7.

14.

The Einstein-Brazil Fogarty: A decade of synergy.

Nosanchuk JD, Nosanchuk MD, Rodrigues ML, Nimrichter L, Carvalho AC, Weiss LM, Spray DC, Tanowitz HB.

Braz J Microbiol. 2015 Oct-Dec;46(4):945-55. doi: 10.1590/S1517-838246420140975. Review.

15.

Strain-induced mechanotransduction through primary cilia, extracellular ATP, purinergic calcium signaling, and ERK1/2 transactivates CITED2 and downregulates MMP-1 and MMP-13 gene expression in chondrocytes.

He Z, Leong DJ, Zhuo Z, Majeska RJ, Cardoso L, Spray DC, Goldring MB, Cobelli NJ, Sun HB.

Osteoarthritis Cartilage. 2016 May;24(5):892-901. doi: 10.1016/j.joca.2015.11.015. Epub 2015 Dec 12.

16.

Pannexin-1 and P2X7-Receptor Are Required for Apoptotic Osteocytes in Fatigued Bone to Trigger RANKL Production in Neighboring Bystander Osteocytes.

Cheung WY, Fritton JC, Morgan SA, Seref-Ferlengez Z, Basta-Pljakic J, Thi MM, Suadicani SO, Spray DC, Majeska RJ, Schaffler MB.

J Bone Miner Res. 2016 Apr;31(4):890-9. doi: 10.1002/jbmr.2740. Epub 2016 Jan 20.

17.

Developments in the management of Chagas cardiomyopathy.

Tanowitz HB, Machado FS, Spray DC, Friedman JM, Weiss OS, Lora JN, Nagajyothi J, Moraes DN, Garg NJ, Nunes MC, Ribeiro AL.

Expert Rev Cardiovasc Ther. 2015 Dec;13(12):1393-409. doi: 10.1586/14779072.2015.1103648. Epub 2015 Oct 23. Review.

18.

The speed of swelling kinetics modulates cell volume regulation and calcium signaling in astrocytes: A different point of view on the role of aquaporins.

Mola MG, Sparaneo A, Gargano CD, Spray DC, Svelto M, Frigeri A, Scemes E, Nicchia GP.

Glia. 2016 Jan;64(1):139-54. doi: 10.1002/glia.22921. Epub 2015 Sep 28.

19.

Connexin Type and Fluorescent Protein Fusion Tag Determine Structural Stability of Gap Junction Plaques.

Stout RF Jr, Snapp EL, Spray DC.

J Biol Chem. 2015 Sep 25;290(39):23497-514. doi: 10.1074/jbc.M115.659979. Epub 2015 Aug 11.

20.

Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse post-traumatic osteoarthritis model.

Leong DJ, Choudhury M, Hanstein R, Hirsh DM, Kim SJ, Majeska RJ, Schaffler MB, Hardin JA, Spray DC, Goldring MB, Cobelli NJ, Sun HB.

Arthritis Res Ther. 2014 Dec 17;16(6):508. doi: 10.1186/s13075-014-0508-y.

21.

Gap junctional communication in health and disease.

Zoidl G, Spray DC.

Front Physiol. 2014 Nov 21;5:442. doi: 10.3389/fphys.2014.00442. eCollection 2014. No abstract available.

22.

Molecular imaging, biodistribution and efficacy of mesenchymal bone marrow cell therapy in a mouse model of Chagas disease.

Jasmin, Jelicks LA, Tanowitz HB, Peters VM, Mendez-Otero R, de Carvalho ACC, Spray DC.

Microbes Infect. 2014 Nov;16(11):923-935. doi: 10.1016/j.micinf.2014.08.016. Epub 2014 Sep 16.

23.

Pannexin 1 channels play essential roles in urothelial mechanotransduction and intercellular signaling.

Negoro H, Urban-Maldonado M, Liou LS, Spray DC, Thi MM, Suadicani SO.

PLoS One. 2014 Aug 29;9(8):e106269. doi: 10.1371/journal.pone.0106269. eCollection 2014.

24.

Adipocytes in both brown and white adipose tissue of adult mice are functionally connected via gap junctions: implications for Chagas disease.

Burke S, Nagajyothi F, Thi MM, Hanani M, Scherer PE, Tanowitz HB, Spray DC.

Microbes Infect. 2014 Nov;16(11):893-901. doi: 10.1016/j.micinf.2014.08.006. Epub 2014 Aug 21.

25.

Inhibitors of the 5-lipoxygenase pathway activate pannexin1 channels in macrophages via the thromboxane receptor.

da Silva-Souza HA, de Lira MN, Patel NK, Spray DC, Persechini PM, Scemes E.

Am J Physiol Cell Physiol. 2014 Sep 15;307(6):C571-9. doi: 10.1152/ajpcell.00087.2014. Epub 2014 Jul 30.

26.

Structural order in Pannexin 1 cytoplasmic domains.

Spagnol G, Sorgen PL, Spray DC.

Channels (Austin). 2014;8(2):157-66. doi: 10.4161/chan.28854. Epub 2014 Apr 21.

27.

Connexins modulate autophagosome biogenesis.

Bejarano E, Yuste A, Patel B, Stout RF Jr, Spray DC, Cuervo AM.

Nat Cell Biol. 2014 May;16(5):401-14. doi: 10.1038/ncb2934. Epub 2014 Apr 6.

28.

Shear-induced endothelial NOS activation and remodeling via heparan sulfate, glypican-1, and syndecan-1.

Ebong EE, Lopez-Quintero SV, Rizzo V, Spray DC, Tarbell JM.

Integr Biol (Camb). 2014 Mar;6(3):338-47. doi: 10.1039/c3ib40199e. Epub 2014 Jan 30.

29.

Human liver cell trafficking mutants: characterization and whole exome sequencing.

Yuan F, Snapp EL, Novikoff PM, Suadicani SO, Spray DC, Potvin B, Wolkoff AW, Stanley P.

PLoS One. 2014 Jan 23;9(1):e87043. doi: 10.1371/journal.pone.0087043. eCollection 2014.

30.

Mechanosensory responses of osteocytes to physiological forces occur along processes and not cell body and require αVβ3 integrin.

Thi MM, Suadicani SO, Schaffler MB, Weinbaum S, Spray DC.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21012-7. doi: 10.1073/pnas.1321210110. Epub 2013 Dec 9.

31.

High glucose attenuates shear-induced changes in endothelial hydraulic conductivity by degrading the glycocalyx.

Lopez-Quintero SV, Cancel LM, Pierides A, Antonetti D, Spray DC, Tarbell JM.

PLoS One. 2013 Nov 18;8(11):e78954. doi: 10.1371/journal.pone.0078954. eCollection 2013.

32.

Disruption of calcium homeostasis in cardiomyocytes underlies cardiac structural and functional changes in severe sepsis.

Celes MR, Malvestio LM, Suadicani SO, Prado CM, Figueiredo MJ, Campos EC, Freitas AC, Spray DC, Tanowitz HB, da Silva JS, Rossi MA.

PLoS One. 2013 Jul 23;8(7):e68809. doi: 10.1371/journal.pone.0068809. Print 2013.

33.

Matrix-dependent adhesion mediates network responses to physiological stimulation of the osteocyte cell process.

Wu D, Schaffler MB, Weinbaum S, Spray DC.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12096-101. doi: 10.1073/pnas.1310003110. Epub 2013 Jul 1.

34.

Promises and pitfalls of a Pannexin1 transgenic mouse line.

Hanstein R, Negoro H, Patel NK, Charollais A, Meda P, Spray DC, Suadicani SO, Scemes E.

Front Pharmacol. 2013 May 9;4:61. doi: 10.3389/fphar.2013.00061. eCollection 2013.

35.

Gap junctions and Bystander Effects: Good Samaritans and executioners.

Spray DC, Hanstein R, Lopez-Quintero SV, Stout RF Jr, Suadicani SO, Thi MM.

Wiley Interdiscip Rev Membr Transp Signal. 2013 Jan;2(1):1-15. Epub 2012 Dec 11.

36.

Transcriptome profiling of hippocampal CA1 after early-life seizure-induced preconditioning may elucidate new genetic therapies for epilepsy.

Friedman LK, Mancuso J, Patel A, Kudur V, Leheste JR, Iacobas S, Botta J, Iacobas DA, Spray DC.

Eur J Neurosci. 2013 Jul;38(1):2139-52. doi: 10.1111/ejn.12168. Epub 2013 Apr 4.

37.

Identification of a functional prostanoid-like receptor in the protozoan parasite, Trypanosoma cruzi.

Mukherjee S, Sadekar N, Ashton AW, Huang H, Spray DC, Lisanti MP, Machado FS, Weiss LM, Tanowitz HB.

Parasitol Res. 2013 Apr;112(4):1417-25. doi: 10.1007/s00436-012-3271-5. Epub 2013 Feb 13.

38.

Mesenchymal bone marrow cell therapy in a mouse model of chagas disease. Where do the cells go?

Jasmin, Jelicks LA, Koba W, Tanowitz HB, Mendez-Otero R, Campos de Carvalho AC, Spray DC.

PLoS Negl Trop Dis. 2012;6(12):e1971. doi: 10.1371/journal.pntd.0001971. Epub 2012 Dec 13.

39.

Electrical synapses getting translational.

Dermietzel R, Spray DC.

Brain Res. 2012 Dec 3;1487:1-2. doi: 10.1016/j.brainres.2012.10.058. No abstract available.

PMID:
23157983
40.

Altered regulation of Akt signaling with murine cerebral malaria, effects on long-term neuro-cognitive function, restoration with lithium treatment.

Dai M, Freeman B, Shikani HJ, Bruno FP, Collado JE, Macias R, Reznik SE, Davies P, Spray DC, Tanowitz HB, Weiss LM, Desruisseaux MS.

PLoS One. 2012;7(10):e44117. doi: 10.1371/journal.pone.0044117. Epub 2012 Oct 17.

41.

Connexin43 and pannexin1 channels in osteoblasts: who is the "hemichannel"?

Thi MM, Islam S, Suadicani SO, Spray DC.

J Membr Biol. 2012 Jul;245(7):401-9. doi: 10.1007/s00232-012-9462-2. Epub 2012 Jul 15.

42.

Calmodulin dependent protein kinase increases conductance at gap junctions formed by the neuronal gap junction protein connexin36.

Del Corsso C, Iglesias R, Zoidl G, Dermietzel R, Spray DC.

Brain Res. 2012 Dec 3;1487:69-77. doi: 10.1016/j.brainres.2012.06.058. Epub 2012 Jul 13.

43.

Labeling stem cells with superparamagnetic iron oxide nanoparticles: analysis of the labeling efficacy by microscopy and magnetic resonance imaging.

Jasmin, Torres AL, Jelicks L, de Carvalho AC, Spray DC, Mendez-Otero R.

Methods Mol Biol. 2012;906:239-52. doi: 10.1007/978-1-61779-953-2_18.

44.

The connexin43-dependent transcriptome during brain development: importance of genetic background.

Iacobas S, Iacobas DA, Spray DC, Scemes E.

Brain Res. 2012 Dec 3;1487:131-9. doi: 10.1016/j.brainres.2012.05.062. Epub 2012 Jul 5.

45.

ATP signaling is deficient in cultured Pannexin1-null mouse astrocytes.

Suadicani SO, Iglesias R, Wang J, Dahl G, Spray DC, Scemes E.

Glia. 2012 Jul;60(7):1106-16. doi: 10.1002/glia.22338. Epub 2012 Apr 12.

46.

Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner.

Bejarano E, Girao H, Yuste A, Patel B, Marques C, Spray DC, Pereira P, Cuervo AM.

Mol Biol Cell. 2012 Jun;23(11):2156-69. doi: 10.1091/mbc.E11-10-0844. Epub 2012 Apr 11.

47.

Extracellular K⁺ and astrocyte signaling via connexin and pannexin channels.

Scemes E, Spray DC.

Neurochem Res. 2012 Nov;37(11):2310-6. doi: 10.1007/s11064-012-0759-4. Epub 2012 Apr 6. Review.

48.

Pannexin1-mediated ATP release provides signal transmission between Neuro2A cells.

Iglesias RM, Spray DC.

Neurochem Res. 2012 Jun;37(6):1355-63. doi: 10.1007/s11064-012-0720-6. Epub 2012 Feb 23.

49.

Chagas heart disease: report on recent developments.

Machado FS, Jelicks LA, Kirchhoff LV, Shirani J, Nagajyothi F, Mukherjee S, Nelson R, Coyle CM, Spray DC, de Carvalho AC, Guan F, Prado CM, Lisanti MP, Weiss LM, Montgomery SP, Tanowitz HB.

Cardiol Rev. 2012 Mar-Apr;20(2):53-65. doi: 10.1097/CRD.0b013e31823efde2. Review.

50.

Glial cells in (patho)physiology.

Parpura V, Heneka MT, Montana V, Oliet SH, Schousboe A, Haydon PG, Stout RF Jr, Spray DC, Reichenbach A, Pannicke T, Pekny M, Pekna M, Zorec R, Verkhratsky A.

J Neurochem. 2012 Apr;121(1):4-27. doi: 10.1111/j.1471-4159.2012.07664.x. Epub 2012 Feb 2. Review.

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