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Modafinil treatment modulates functional connectivity in stroke survivors with severe fatigue.

Visser MM, Goodin P, Parsons MW, Lillicrap T, Spratt NJ, Levi CR, Bivard A.

Sci Rep. 2019 Jul 4;9(1):9660. doi: 10.1038/s41598-019-46149-0.


The unmet needs of carers of stroke survivors: An evaluation of Google search results.

Denham AM, Wynne O, Baker AL, Spratt NJ, Bonevski B.

Health Informatics J. 2019 Jun 18:1460458219852530. doi: 10.1177/1460458219852530. [Epub ahead of print]


Exploring the relationship between ischemic core volume and clinical outcomes after thrombectomy or thrombolysis.

Chen C, Parsons MW, Levi CR, Spratt NJ, Miteff F, Lin L, Cheng X, Lou M, Kleinig T, Butcher K, Dong Q, Bivard A.

Neurology. 2019 Jul 16;93(3):e283-e292. doi: 10.1212/WNL.0000000000007768. Epub 2019 Jun 17.


Choroid plexus volume after stroke.

Egorova N, Gottlieb E, Khlif MS, Spratt NJ, Brodtmann A.

Int J Stroke. 2019 May 17:1747493019851277. doi: 10.1177/1747493019851277. [Epub ahead of print]


"This is our life now. Our new normal": A qualitative study of the unmet needs of carers of stroke survivors.

Denham AMJ, Wynne O, Baker AL, Spratt NJ, Turner A, Magin P, Janssen H, English C, Loh M, Bonevski B.

PLoS One. 2019 May 8;14(5):e0216682. doi: 10.1371/journal.pone.0216682. eCollection 2019.


Influence of occlusion site and baseline ischemic core on outcome in patients with ischemic stroke.

Tian H, Parsons MW, Levi CR, Lin L, Aviv RI, Spratt NJ, Butcher KS, Lou M, Kleinig TJ, Bivard A.

Neurology. 2019 Jun 4;92(23):e2626-e2643. doi: 10.1212/WNL.0000000000007553. Epub 2019 May 1.


Predicting Modafinil-Treatment Response in Poststroke Fatigue Using Brain Morphometry and Functional Connectivity.

Visser MM, Maréchal B, Goodin P, Lillicrap TP, Garcia-Esperon C, Spratt NJ, Parsons MW, Levi CR, Bivard A.

Stroke. 2019 Mar;50(3):602-609. doi: 10.1161/STROKEAHA.118.023813.


Breaking up sitting time after stroke - How much less sitting is needed to improve blood pressure after stroke (BUST-BP-Dose): Protocol for a dose-finding study.

Mackie P, Crowfoot G, Janssen H, Dunstan DW, Bernhardt J, Walker FR, Patterson A, Callister R, Spratt NJ, Holliday E, English C.

Contemp Clin Trials Commun. 2018 Dec 2;13:100310. doi: 10.1016/j.conctc.2018.100310. eCollection 2019 Mar.


Single-phase CT angiography: collateral grade is independent of scan weighting.

Bisson DA, Mahmoudian D, Shatil AS, Waggass G, Zhang L, Levi C, Spratt NJ, Lin L, Liebeskind D, Parsons M, Bivard A, Aviv RI.

Neuroradiology. 2019 Jan;61(1):19-28. doi: 10.1007/s00234-018-2105-2. Epub 2018 Oct 4.


Do powered over-ground lower limb robotic exoskeletons affect outcomes in the rehabilitation of people with acquired brain injury?

Postol N, Marquez J, Spartalis S, Bivard A, Spratt NJ.

Disabil Rehabil Assist Technol. 2018 Sep 21:1-12. doi: 10.1080/17483107.2018.1499137. [Epub ahead of print]


Breaking up sitting time after stroke (BUST-stroke).

English C, Janssen H, Crowfoot G, Callister R, Dunn A, Mackie P, Oldmeadow C, Ong LK, Palazzi K, Patterson AJ, Spratt NJ, Walker FR, Bernhardt J, Dunstan DW.

Int J Stroke. 2018 Dec;13(9):921-931. doi: 10.1177/1747493018801222. Epub 2018 Sep 18.


Frequent, short bouts of light-intensity exercises while standing decreases systolic blood pressure: Breaking Up Sitting Time after Stroke (BUST-Stroke) trial.

English C, Janssen H, Crowfoot G, Bourne J, Callister R, Dunn A, Oldmeadow C, Ong LK, Palazzi K, Patterson A, Spratt NJ, Walker FR, Dunstan DW, Bernhardt J.

Int J Stroke. 2018 Dec;13(9):932-940. doi: 10.1177/1747493018798535. Epub 2018 Sep 17.


Heptanoate is neuroprotective in vitro but triheptanoin post-treatment did not protect against middle cerebral artery occlusion in rats.

Tan KN, Hood R, Warren K, Pepperall D, Carrasco-Pozo C, Manzanero S, Borges K, Spratt NJ.

Neurosci Lett. 2018 Sep 14;683:207-214. doi: 10.1016/j.neulet.2018.07.045. Epub 2018 Aug 1.


Intravenous Thrombolysis May Not Improve Clinical Outcome of Acute Ischemic Stroke Patients Without a Baseline Vessel Occlusion.

Tian H, Parsons MW, Levi CR, Cheng X, Aviv RI, Spratt NJ, Kleinig TJ, O'Brien B, Butcher KS, Lin L, Zhang J, Dong Q, Chen C, Bivard A.

Front Neurol. 2018 Jun 6;9:405. doi: 10.3389/fneur.2018.00405. eCollection 2018.


Evaluation of three measures of cardiorespiratory fitness in independently ambulant stroke survivors.

Dunn A, Marsden DL, Barker D, van Vliet P, Spratt NJ, Callister R.

Physiother Theory Pract. 2019 Jul;35(7):622-632. doi: 10.1080/09593985.2018.1457746. Epub 2018 Mar 30.


Correction for Delay and Dispersion Results in More Accurate Cerebral Blood Flow Ischemic Core Measurement in Acute Stroke.

Lin L, Bivard A, Kleinig T, Spratt NJ, Levi CR, Yang Q, Parsons MW.

Stroke. 2018 Apr;49(4):924-930. doi: 10.1161/STROKEAHA.117.019562. Epub 2018 Mar 2.


Thresholds for infarction vary between gray matter and white matter in acute ischemic stroke: A CT perfusion study.

Chen C, Bivard A, Lin L, Levi CR, Spratt NJ, Parsons MW.

J Cereb Blood Flow Metab. 2019 Mar;39(3):536-546. doi: 10.1177/0271678X17744453. Epub 2017 Nov 27.


Cardiorespiratory fitness and walking endurance improvements after 12 months of an individualised home and community-based exercise programme for people after stroke.

Dunn A, Marsden DL, Barker D, Van Vliet P, Spratt NJ, Callister R.

Brain Inj. 2017;31(12):1617-1624. doi: 10.1080/02699052.2017.1355983. Epub 2017 Sep 5.


The role of Ca2+-calmodulin stimulated protein kinase II in ischaemic stroke - A potential target for neuroprotective therapies.

Rostas JAP, Spratt NJ, Dickson PW, Skelding KA.

Neurochem Int. 2017 Jul;107:33-42. doi: 10.1016/j.neuint.2017.01.012. Epub 2017 Jan 31. Review.


Validating a Predictive Model of Acute Advanced Imaging Biomarkers in Ischemic Stroke.

Bivard A, Levi C, Lin L, Cheng X, Aviv R, Spratt NJ, Lou M, Kleinig T, O'Brien B, Butcher K, Zhang J, Jannes J, Dong Q, Parsons M.

Stroke. 2017 Mar;48(3):645-650. doi: 10.1161/STROKEAHA.116.015143. Epub 2017 Jan 19.


Ischaemia- and excitotoxicity-induced CaMKII-Mediated neuronal cell death: The relative roles of CaMKII autophosphorylation at T286 and T253.

Rostas JA, Hoffman A, Murtha LA, Pepperall D, McLeod DD, Dickson PW, Spratt NJ, Skelding KA.

Neurochem Int. 2017 Mar;104:6-10. doi: 10.1016/j.neuint.2017.01.002. Epub 2017 Jan 5.


Recent progress in translational research on neurovascular and neurodegenerative disorders.

Demuth HU, Dijkhuizen RM, Farr TD, Gelderblom M, Horsburgh K, Iadecola C, Mcleod DD, Michalski D, Murphy TH, Orbe J, Otte WM, Petzold GC, Plesnila N, Reiser G, Reymann KG, Rueger MA, Saur D, Savitz SI, Schilling S, Spratt NJ, Turner RJ, Vemuganti R, Vivien D, Yepes M, Zille M, Boltze J; ISN&N meeting contributors.

Restor Neurol Neurosci. 2017;35(1):87-103. doi: 10.3233/RNN-160690. Review.


Breaking up sitting time after stroke (BUST-Stroke).

Janssen H, Dunstan DW, Bernhardt J, Walker FR, Patterson A, Callister R, Dunn A, Spratt NJ, English C.

Int J Stroke. 2017 Jun;12(4):425-429. doi: 10.1177/1747493016676616. Epub 2016 Oct 28.


Effectiveness of a Brief Dietetic Intervention for Hyperlipidaemic Adults Using Individually-Tailored Dietary Feedback.

Schumacher TL, Burrows TL, Rollo ME, Spratt NJ, Callister R, Collins CE.

Healthcare (Basel). 2016 Oct 11;4(4). pii: E75.


The Role of Family in a Dietary Risk Reduction Intervention for Cardiovascular Disease.

Schumacher TL, Burrows TL, Thompson DI, Callister R, Spratt NJ, Collins CE.

Healthcare (Basel). 2016 Sep 30;4(4). pii: E74.


Independently ambulant, community-dwelling stroke survivors have reduced cardiorespiratory fitness, mobility and knee strength compared to an age- and gender-matched cohort.

Dunn A, Marsden DL, Van Vliet P, Spratt NJ, Callister R.

Top Stroke Rehabil. 2017 Apr;24(3):163-169. doi: 10.1080/10749357.2016.1236482. Epub 2016 Sep 27.


A Home- and Community-Based Physical Activity Program Can Improve the Cardiorespiratory Fitness and Walking Capacity of Stroke Survivors.

Marsden DL, Dunn A, Callister R, McElduff P, Levi CR, Spratt NJ.

J Stroke Cerebrovasc Dis. 2016 Oct;25(10):2386-98. doi: 10.1016/j.jstrokecerebrovasdis.2016.06.007. Epub 2016 Jul 1.


Intracranial Pressure Elevation 24 h after Ischemic Stroke in Aged Rats Is Prevented by Early, Short Hypothermia Treatment.

Murtha LA, Beard DJ, Bourke JT, Pepperall D, McLeod DD, Spratt NJ.

Front Aging Neurosci. 2016 May 27;8:124. doi: 10.3389/fnagi.2016.00124. eCollection 2016.


Sonothrombolysis with BR38 Microbubbles Improves Microvascular Patency in a Rat Model of Stroke.

Schleicher N, Tomkins AJ, Kampschulte M, Hyvelin JM, Botteron C, Juenemann M, Yeniguen M, Krombach GA, Kaps M, Spratt NJ, Gerriets T, Nedelmann M.

PLoS One. 2016 Apr 14;11(4):e0152898. doi: 10.1371/journal.pone.0152898. eCollection 2016.


Thrombolytic Recanalization of Carotid Arteries Is Highly Dependent on Degree of Stenosis, Despite Sonothrombolysis.

Tomkins AJ, Hood RJ, Pepperall D, Null CL, Levi CR, Spratt NJ.

J Am Heart Assoc. 2016 Feb 23;5(2). pii: e002716. doi: 10.1161/JAHA.115.002716.


Relationship Between Collateral Status, Contrast Transit, and Contrast Density in Acute Ischemic Stroke.

Kawano H, Bivard A, Lin L, Spratt NJ, Miteff F, Parsons MW, Levi CR.

Stroke. 2016 Mar;47(3):742-9. doi: 10.1161/STROKEAHA.115.011320. Epub 2016 Feb 2.


Intracranial Pressure and Collateral Blood Flow.

Beard DJ, Murtha LA, McLeod DD, Spratt NJ.

Stroke. 2016 Jun;47(6):1695-700. doi: 10.1161/STROKEAHA.115.011147. Epub 2016 Jan 19. Review. No abstract available.


Ischemic penumbra as a trigger for intracranial pressure rise - A potential cause for collateral failure and infarct progression?

Beard DJ, Logan CL, McLeod DD, Hood RJ, Pepperall D, Murtha LA, Spratt NJ.

J Cereb Blood Flow Metab. 2016 May;36(5):917-27. doi: 10.1177/0271678X15625578. Epub 2016 Jan 12.


A comprehensive analysis of metabolic changes in the salvaged penumbra.

Bivard A, Yassi N, Krishnamurthy V, Lin L, Levi C, Spratt NJ, Mittef F, Davis S, Parsons M.

Neuroradiology. 2016 Apr;58(4):409-15. doi: 10.1007/s00234-015-1638-x. Epub 2016 Jan 6.


Intracranial pressure elevation after ischemic stroke in rats: cerebral edema is not the only cause, and short-duration mild hypothermia is a highly effective preventive therapy.

Murtha LA, McLeod DD, Pepperall D, McCann SK, Beard DJ, Tomkins AJ, Holmes WM, McCabe C, Macrae IM, Spratt NJ.

J Cereb Blood Flow Metab. 2015 Dec;35(12):2109. doi: 10.1038/jcbfm.2015.209.


Feasibility of Recruiting Families into a Heart Disease Prevention Program Based on Dietary Patterns.

Schumacher TL, Burrows TL, Thompson DI, Spratt NJ, Callister R, Collins CE.

Nutrients. 2015 Aug 21;7(8):7042-57. doi: 10.3390/nu7085323.


Perfusion computed tomography to assist decision making for stroke thrombolysis.

Bivard A, Levi C, Krishnamurthy V, McElduff P, Miteff F, Spratt NJ, Bateman G, Donnan G, Davis S, Parsons M.

Brain. 2015 Jul;138(Pt 7):1919-31. doi: 10.1093/brain/awv071. Epub 2015 Mar 25.


Protocol variations and six-minute walk test performance in stroke survivors: a systematic review with meta-analysis.

Dunn A, Marsden DL, Nugent E, Van Vliet P, Spratt NJ, Attia J, Callister R.

Stroke Res Treat. 2015;2015:484813. doi: 10.1155/2015/484813. Epub 2015 Jan 20. Review.


Intracranial pressure elevation reduces flow through collateral vessels and the penetrating arterioles they supply. A possible explanation for 'collateral failure' and infarct expansion after ischemic stroke.

Beard DJ, McLeod DD, Logan CL, Murtha LA, Imtiaz MS, van Helden DF, Spratt NJ.

J Cereb Blood Flow Metab. 2015 May;35(5):861-72. doi: 10.1038/jcbfm.2015.2. Epub 2015 Feb 11.


Platelet rich clots are resistant to lysis by thrombolytic therapy in a rat model of embolic stroke.

Tomkins AJ, Schleicher N, Murtha L, Kaps M, Levi CR, Nedelmann M, Spratt NJ.

Exp Transl Stroke Med. 2015 Jan 27;7:2. doi: 10.1186/s13231-014-0014-y. eCollection 2015.


Intracranial pressure elevation after ischemic stroke in rats: cerebral edema is not the only cause, and short-duration mild hypothermia is a highly effective preventive therapy.

Murtha LA, McLeod DD, Pepperall D, McCann SK, Beard DJ, Tomkins AJ, Holmes WM, McCabe C, Macrae IM, Spratt NJ.

J Cereb Blood Flow Metab. 2015 Mar 31;35(4):592-600. doi: 10.1038/jcbfm.2014.230. Erratum in: J Cereb Blood Flow Metab. 2015 Dec;35(12):2109.


Spectroscopy of reperfused tissue after stroke reveals heightened metabolism in patients with good clinical outcomes.

Bivard A, Krishnamurthy V, Stanwell P, Yassi N, Spratt NJ, Nilsson M, Levi CR, Davis S, Parsons MW.

J Cereb Blood Flow Metab. 2014 Dec;34(12):1944-50. doi: 10.1038/jcbfm.2014.166. Epub 2014 Oct 1.


Allopregnanolone and its precursor progesterone do not reduce injury after experimental stroke in hypertensive rats - role of postoperative temperature regulation?

Spratt NJ, Tomkins AJ, Pepperall D, McLeod DD, Calford MB.

PLoS One. 2014 Sep 23;9(9):e107752. doi: 10.1371/journal.pone.0107752. eCollection 2014.


Cerebrospinal fluid is drained primarily via the spinal canal and olfactory route in young and aged spontaneously hypertensive rats.

Murtha LA, Yang Q, Parsons MW, Levi CR, Beard DJ, Spratt NJ, McLeod DD.

Fluids Barriers CNS. 2014 Jun 6;11:12. doi: 10.1186/2045-8118-11-12. eCollection 2014.


Exercise reduces infarct volume and facilitates neurobehavioral recovery: results from a systematic review and meta-analysis of exercise in experimental models of focal ischemia.

Egan KJ, Janssen H, Sena ES, Longley L, Speare S, Howells DW, Spratt NJ, Macleod MR, Mead GE, Bernhardt J.

Neurorehabil Neural Repair. 2014 Oct;28(8):800-12. doi: 10.1177/1545968314521694. Epub 2014 Feb 18. Review.


Arterial spin labeling versus bolus-tracking perfusion in hyperacute stroke.

Bivard A, Krishnamurthy V, Stanwell P, Levi C, Spratt NJ, Davis S, Parsons M.

Stroke. 2014 Jan;45(1):127-33. doi: 10.1161/STROKEAHA.113.003218. Epub 2013 Dec 3.


Perfusion computed tomography thresholds defining ischemic penumbra and infarct core: studies in a rat stroke model.

McLeod DD, Parsons MW, Hood R, Hiles B, Allen J, McCann SK, Murtha L, Calford MB, Levi CR, Spratt NJ.

Int J Stroke. 2015 Jun;10(4):553-9. doi: 10.1111/ijs.12147. Epub 2013 Oct 21.


Inadvertent occlusion of the anterior choroidal artery explains infarct variability in the middle cerebral artery thread occlusion stroke model.

McLeod DD, Beard DJ, Parsons MW, Levi CR, Calford MB, Spratt NJ.

PLoS One. 2013 Sep 17;8(9):e75779. doi: 10.1371/journal.pone.0075779. eCollection 2013.


Short-duration hypothermia after ischemic stroke prevents delayed intracranial pressure rise.

Murtha LA, McLeod DD, McCann SK, Pepperall D, Chung S, Levi CR, Calford MB, Spratt NJ.

Int J Stroke. 2014 Jul;9(5):553-9. doi: 10.1111/ijs.12181. Epub 2013 Sep 12.


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