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Items: 1 to 50 of 54

1.

Modest and non-essential roles of the endocannabinoid system in immature hematopoiesis of mice.

Danner E, Hoffmann F, Lee SY, Cordes F, Orban S, Dauber K, Chudziak D, Spohn G, Wiercinska E, Tast B, Karpova D, Bonig H.

Exp Hematol. 2019 Sep 25. pii: S0301-472X(19)31020-3. doi: 10.1016/j.exphem.2019.09.022. [Epub ahead of print]

PMID:
31562901
2.

Molecular signature of human bone marrow-derived mesenchymal stromal cell subsets.

Kuçi S, Kuçi Z, Schäfer R, Spohn G, Winter S, Schwab M, Salzmann-Manrique E, Klingebiel T, Bader P.

Sci Rep. 2019 Feb 11;9(1):1774. doi: 10.1038/s41598-019-38517-7.

3.

A case of segmental Darier disease treated with doxycycline monotherapy.

Pettit C, Ulman CA, Spohn G, Kaffenberger J.

Dermatol Online J. 2018 Mar 15;24(3). pii: 13030/qt2827h6qq.

4.

Continuous blockade of CXCR4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells.

Karpova D, Ritchey JK, Holt MS, Abou-Ezzi G, Monlish D, Batoon L, Millard S, Spohn G, Wiercinska E, Chendamarai E, Yang W, Christ S, Gehrs L, Schuettpelz LG, Dembowsky K, Pettit AR, Rettig MP, Bonig H, DiPersio JF.

Blood. 2017 May 25;129(21):2939-2949. doi: 10.1182/blood-2016-10-746909. Epub 2017 Apr 11.

5.

Human mesenchymal stromal cells undergo apoptosis and fragmentation after intravenous application in immune-competent mice.

Leibacher J, Dauber K, Ehser S, Brixner V, Kollar K, Vogel A, Spohn G, Schäfer R, Seifried E, Henschler R.

Cytotherapy. 2017 Jan;19(1):61-74. doi: 10.1016/j.jcyt.2016.09.010. Epub 2016 Nov 8.

PMID:
27836573
6.

Endogenous polyclonal anti-IL-1 antibody responses potentiate IL-1 activity during pathogenic inflammation.

Spohn G, Arenas-Ramirez N, Bouchaud G, Boyman O.

J Allergy Clin Immunol. 2017 Jun;139(6):1957-1965.e3. doi: 10.1016/j.jaci.2016.09.033. Epub 2016 Nov 7.

PMID:
27833025
7.

Mesenchymal Stem/Stromal Cells in Regenerative Medicine: Can Preconditioning Strategies Improve Therapeutic Efficacy?

Schäfer R, Spohn G, Baer PC.

Transfus Med Hemother. 2016 Jul;43(4):256-267. Epub 2016 Jul 20.

8.

Mucin in the dermis: a case of tender tumors.

Ferris GJ, Spohn GP, Gru A, Kaffenberger J.

Dermatol Online J. 2016 Aug 15;22(8). pii: 13030/qt4b50f4zf.

PMID:
27617942
10.

Delayed-Onset Sclerema Neonatorum in a Critically Ill Premature Infant.

Spohn GP, Pietras TA, Stone MS.

Pediatr Dermatol. 2016 Mar-Apr;33(2):e168-9. doi: 10.1111/pde.12814.

PMID:
27001336
11.

Development of an Interleukin-1β Vaccine in Patients with Type 2 Diabetes.

Cavelti-Weder C, Timper K, Seelig E, Keller C, Osranek M, Lässing U, Spohn G, Maurer P, Müller P, Jennings GT, Willers J, Saudan P, Donath MY, Bachmann MF.

Mol Ther. 2016 May;24(5):1003-12. doi: 10.1038/mt.2015.227. Epub 2015 Dec 21.

12.

Automated CD34+ cell isolation of peripheral blood stem cell apheresis product.

Spohn G, Wiercinska E, Karpova D, Bunos M, Hümmer C, Wingenfeld E, Sorg N, Poppe C, Huppert V, Stuth J, Reck K, Essl M, Seifried E, Bönig H.

Cytotherapy. 2015 Oct;17(10):1465-71. doi: 10.1016/j.jcyt.2015.04.005. Epub 2015 May 14.

13.

Variant rs1801157 in the 3'UTR of SDF-1ß does not explain variability of healthy-donor G-CSF responsiveness.

Schulz M, Karpova D, Spohn G, Damert A, Seifried E, Binder V, Bönig H.

PLoS One. 2015 Mar 24;10(3):e0121859. doi: 10.1371/journal.pone.0121859. eCollection 2015.

14.

Functional consequences of perturbed CXCL12 signal processing: analyses of immature hematopoiesis in GRK6-deficient mice.

Chudziak D, Spohn G, Karpova D, Dauber K, Wiercinska E, Miettinen JA, Papayannopoulou T, Bönig H.

Stem Cells Dev. 2015 Mar 15;24(6):737-46. doi: 10.1089/scd.2014.0284. Epub 2014 Nov 19.

15.

Preclinical efficacy and safety of an anti-IL-1β vaccine for the treatment of type 2 diabetes.

Spohn G, Schori C, Keller I, Sladko K, Sina C, Guler R, Schwarz K, Johansen P, Jennings GT, Bachmann MF.

Mol Ther Methods Clin Dev. 2014 Oct 22;1:14048. doi: 10.1038/mtm.2014.48. eCollection 2014.

16.

The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor.

Karpova D, Dauber K, Spohn G, Chudziak D, Wiercinska E, Schulz M, Pettit AR, Levesque JP, Romagnoli B, Patel K, Chevalier E, Dembowsky K, Bonig H.

Leukemia. 2013 Dec;27(12):2322-31. doi: 10.1038/leu.2013.266. Epub 2013 Sep 12.

17.

Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy.

Kollmorgen G, Niederfellner G, Lifke A, Spohn GJ, Rieder N, Harring SV, Bauss F, Burtscher H, Lammers R, Bossenmaier B.

Mol Oncol. 2013 Dec;7(6):1142-51. doi: 10.1016/j.molonc.2013.08.009. Epub 2013 Sep 3.

18.

VKORC1L1, an enzyme rescuing the vitamin K 2,3-epoxide reductase activity in some extrahepatic tissues during anticoagulation therapy.

Hammed A, Matagrin B, Spohn G, Prouillac C, Benoit E, Lattard V.

J Biol Chem. 2013 Oct 4;288(40):28733-42. doi: 10.1074/jbc.M113.457119. Epub 2013 Aug 8.

19.

Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice.

Pal M, Wunderlich CM, Spohn G, Brönneke HS, Schmidt-Supprian M, Wunderlich FT.

PLoS One. 2013;8(1):e54247. doi: 10.1371/journal.pone.0054247. Epub 2013 Jan 17.

20.

A VLP-based vaccine against interleukin-1α protects mice from atherosclerosis.

Tissot AC, Spohn G, Jennings GT, Shamshiev A, Kurrer MO, Windak R, Meier M, Viesti M, Hersberger M, Kündig TM, Ricci R, Bachmann MF.

Eur J Immunol. 2013 Mar;43(3):716-22. doi: 10.1002/eji.201242687. Epub 2013 Jan 28.

21.

Apheresis product identification in the transplant center: development of point-of-care protocols for extended blood typing of stem cell apheresis products.

Cummerow C, Schwind P, Spicher M, Spohn G, Geisen C, Seifried E, Bönig H.

Bone Marrow Transplant. 2012 Jun;47(6):860-5. doi: 10.1038/bmt.2011.182. Epub 2011 Sep 19.

PMID:
21927033
22.

A recombinant influenza A virus expressing domain III of West Nile virus induces protective immune responses against influenza and West Nile virus.

Martina BE, van den Doel P, Koraka P, van Amerongen G, Spohn G, Haagmans BL, Provacia LB, Osterhaus AD, Rimmelzwaan GF.

PLoS One. 2011 Apr 26;6(4):e18995. doi: 10.1371/journal.pone.0018995.

23.

Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis.

Freigang S, Ampenberger F, Spohn G, Heer S, Shamshiev AT, Kisielow J, Hersberger M, Yamamoto M, Bachmann MF, Kopf M.

Eur J Immunol. 2011 Jul;41(7):2040-51. doi: 10.1002/eji.201041316. Epub 2011 Jun 8.

24.

Validation of a rapid and inexpensive allele-specific amplification (ASA)-PCR genotyping assay for vitamin K antagonist pharmacogenomics.

Spohn G, Geisen C, Luxembourg B, Sittinger K, Seifried E, Bönig H.

Mol Diagn Ther. 2011 Feb 1;15(1):13-9. doi: 10.2165/11588300-000000000-00000. Erratum in: Mol Diagn Ther. 2011 Jun 1;15(3):142-4.

PMID:
21469766
25.

Motility, Chemotaxis, and Flagella.

Spohn G, Scarlato V.

In: Mobley HLT, Mendz GL, Hazell SL, editors. Helicobacter pylori: Physiology and Genetics. Washington (DC): ASM Press; 2001. Chapter 21.

26.

Blocking IL-1α but not IL-1β increases susceptibility to chronic Mycobacterium tuberculosis infection in mice.

Guler R, Parihar SP, Spohn G, Johansen P, Brombacher F, Bachmann MF.

Vaccine. 2011 Feb 1;29(6):1339-46. doi: 10.1016/j.vaccine.2010.10.045. Epub 2010 Nov 18.

PMID:
21093494
27.

Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment.

Watzka M, Geisen C, Bevans CG, Sittinger K, Spohn G, Rost S, Seifried E, Müller CR, Oldenburg J.

J Thromb Haemost. 2011 Jan;9(1):109-18. doi: 10.1111/j.1538-7836.2010.04095.x.

28.

A VLP-based vaccine targeting domain III of the West Nile virus E protein protects from lethal infection in mice.

Spohn G, Jennings GT, Martina BE, Keller I, Beck M, Pumpens P, Osterhaus AD, Bachmann MF.

Virol J. 2010 Jul 6;7:146. doi: 10.1186/1743-422X-7-146.

29.

Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism.

Belgardt BF, Mauer J, Wunderlich FT, Ernst MB, Pal M, Spohn G, Brönneke HS, Brodesser S, Hampel B, Schauss AC, Brüning JC.

Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6028-33. doi: 10.1073/pnas.1001796107. Epub 2010 Mar 15.

30.

VKORC1 deficiency in mice causes early postnatal lethality due to severe bleeding.

Spohn G, Kleinridders A, Wunderlich FT, Watzka M, Zaucke F, Blumbach K, Geisen C, Seifried E, Müller C, Paulsson M, Brüning JC, Oldenburg J.

Thromb Haemost. 2009 Jun;101(6):1044-50.

PMID:
19492146
31.

Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis.

Spohn G, Keller I, Beck M, Grest P, Jennings GT, Bachmann MF.

Eur J Immunol. 2008 Mar;38(3):877-87. doi: 10.1002/eji.200737989.

32.

Exploiting viral properties for the rational design of modern vaccines.

Spohn G, Bachmann MF.

Expert Rev Vaccines. 2008 Feb;7(1):43-54. doi: 10.1586/14760584.7.1.43. Review.

PMID:
18251693
33.

Targeting osteoporosis and rheumatoid arthritis by active vaccination against RANKL.

Spohn G, Bachmann MF.

Adv Exp Med Biol. 2007;602:135-42. No abstract available.

PMID:
17966398
34.

Transcriptional regulation of stress response and motility functions in Helicobacter pylori is mediated by HspR and HrcA.

Roncarati D, Danielli A, Spohn G, Delany I, Scarlato V.

J Bacteriol. 2007 Oct;189(20):7234-43. Epub 2007 Aug 10.

35.

A virus-like particle-based vaccine selectively targeting soluble TNF-alpha protects from arthritis without inducing reactivation of latent tuberculosis.

Spohn G, Guler R, Johansen P, Keller I, Jacobs M, Beck M, Rohner F, Bauer M, Dietmeier K, Kündig TM, Jennings GT, Brombacher F, Bachmann MF.

J Immunol. 2007 Jun 1;178(11):7450-7.

36.

Regulated polyploidy in halophilic archaea.

Breuert S, Allers T, Spohn G, Soppa J.

PLoS One. 2006 Dec 20;1:e92.

37.

Expression, purification and characterization of the membrane-associated HrcA repressor protein of Helicobacter pylori.

Roncarati D, Spohn G, Tango N, Danielli A, Delany I, Scarlato V.

Protein Expr Purif. 2007 Feb;51(2):267-75. Epub 2006 Aug 17.

PMID:
16997572
38.

Protection against osteoporosis by active immunization with TRANCE/RANKL displayed on virus-like particles.

Spohn G, Schwarz K, Maurer P, Illges H, Rajasekaran N, Choi Y, Jennings GT, Bachmann MF.

J Immunol. 2005 Nov 1;175(9):6211-8.

39.

CrgA is an inducible LysR-type regulator of Neisseria meningitidis, acting both as a repressor and as an activator of gene transcription.

Ieva R, Alaimo C, Delany I, Spohn G, Rappuoli R, Scarlato V.

J Bacteriol. 2005 May;187(10):3421-30.

40.

Dual control of Helicobacter pylori heat shock gene transcription by HspR and HrcA.

Spohn G, Danielli A, Roncarati D, Delany I, Rappuoli R, Scarlato V.

J Bacteriol. 2004 May;186(10):2956-65.

41.
42.

Therapeutic vaccination to block receptor-ligand interactions.

Spohn G, Bachmann MF.

Expert Opin Biol Ther. 2003 Jun;3(3):469-76. Review.

PMID:
12783615
43.

Autoregulation of Helicobacter pylori Fur revealed by functional analysis of the iron-binding site.

Delany I, Spohn G, Pacheco AB, Ieva R, Alaimo C, Rappuoli R, Scarlato V.

Mol Microbiol. 2002 Nov;46(4):1107-22.

44.
45.

Characterization of the HspR-mediated stress response in Helicobacter pylori.

Spohn G, Delany I, Rappuoli R, Scarlato V.

J Bacteriol. 2002 Jun;184(11):2925-30.

46.

The Fur repressor controls transcription of iron-activated and -repressed genes in Helicobacter pylori.

Delany I, Spohn G, Rappuoli R, Scarlato V.

Mol Microbiol. 2001 Dec;42(5):1297-309.

47.

In vitro selection of high affinity HspR-binding sites within the genome of Helicobacter pylori.

Delany I, Spohn G, Rappuoli R, Scarlato V.

Gene. 2002 Jan 23;283(1-2):63-9.

PMID:
11867213
48.

Iron-dependent transcription of the frpB gene of Helicobacter pylori is controlled by the Fur repressor protein.

Delany I, Pacheco AB, Spohn G, Rappuoli R, Scarlato V.

J Bacteriol. 2001 Aug;183(16):4932-7.

49.

Regulation of transcription in Helicobacter pylori: simple systems or complex circuits?

Scarlato V, Delany I, Spohn G, Beier D.

Int J Med Microbiol. 2001 May;291(2):107-17. Review.

PMID:
11437334
50.

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