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Items: 16

1.

Inner Hair Cell and Neuron Degeneration Contribute to Hearing Loss in a DFNA2-Like Mouse Model.

Carignano C, Barila EP, Rías EI, Dionisio L, Aztiria E, Spitzmaul G.

Neuroscience. 2019 Jul 1;410:202-216. doi: 10.1016/j.neuroscience.2019.05.012. Epub 2019 May 16.

PMID:
31102762
2.

Analysis of neuronal nicotinic acetylcholine receptor α4β2 activation at the single-channel level.

Carignano C, Barila EP, Spitzmaul G.

Biochim Biophys Acta. 2016 Sep;1858(9):1964-1973. doi: 10.1016/j.bbamem.2016.05.019. Epub 2016 May 24.

3.

Vestibular role of KCNQ4 and KCNQ5 K+ channels revealed by mouse models.

Spitzmaul G, Tolosa L, Winkelman BH, Heidenreich M, Frens MA, Chabbert C, de Zeeuw CI, Jentsch TJ.

J Biol Chem. 2013 Mar 29;288(13):9334-44. doi: 10.1074/jbc.M112.433383. Epub 2013 Feb 13.

4.

Raising cytosolic Cl- in cerebellar granule cells affects their excitability and vestibulo-ocular learning.

Seja P, Schonewille M, Spitzmaul G, Badura A, Klein I, Rudhard Y, Wisden W, Hübner CA, De Zeeuw CI, Jentsch TJ.

EMBO J. 2012 Mar 7;31(5):1217-30. doi: 10.1038/emboj.2011.488. Epub 2012 Jan 17.

5.

The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus.

Tzingounis AV, Heidenreich M, Kharkovets T, Spitzmaul G, Jensen HS, Nicoll RA, Jentsch TJ.

Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10232-7. doi: 10.1073/pnas.1004644107. Epub 2010 May 13.

6.

The local anaesthetics proadifen and adiphenine inhibit nicotinic receptors by different molecular mechanisms.

Spitzmaul G, Gumilar F, Dilger JP, Bouzat C.

Br J Pharmacol. 2009 Jul;157(5):804-17. doi: 10.1111/j.1476-5381.2009.00214.x. Epub 2009 Apr 30.

7.

Role of pairwise interactions between M1 and M2 domains of the nicotinic receptor in channel gating.

Corradi J, Spitzmaul G, De Rosa MJ, Costabel M, Bouzat C.

Biophys J. 2007 Jan 1;92(1):76-86. Epub 2006 Oct 6.

8.

Molecular mechanisms and binding site location for the noncompetitive antagonist crystal violet on nicotinic acetylcholine receptors.

Arias HR, Bhumireddy P, Spitzmaul G, Trudell JR, Bouzat C.

Biochemistry. 2006 Feb 21;45(7):2014-26.

PMID:
16475790
9.

Single-channel kinetic analysis of chimeric alpha7-5HT3A receptors.

Rayes D, Spitzmaul G, Sine SM, Bouzat C.

Mol Pharmacol. 2005 Nov;68(5):1475-83. Epub 2005 Aug 23.

PMID:
16118362
10.

Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel.

Bouzat C, Gumilar F, Spitzmaul G, Wang HL, Rayes D, Hansen SB, Taylor P, Sine SM.

Nature. 2004 Aug 19;430(7002):896-900.

PMID:
15318223
11.

Mechanistic contributions of residues in the M1 transmembrane domain of the nicotinic receptor to channel gating.

Spitzmaul G, Corradi J, Bouzat C.

Mol Membr Biol. 2004 Jan-Feb;21(1):39-50.

PMID:
14668137
12.

Molecular mechanisms of inhibition of nicotinic acetylcholine receptors by tricyclic antidepressants.

Gumilar F, Arias HR, Spitzmaul G, Bouzat C.

Neuropharmacology. 2003 Dec;45(7):964-76.

PMID:
14573389
13.

Nicotinic receptor M3 transmembrane domain: position 8' contributes to channel gating.

De Rosa MJ, Rayes D, Spitzmaul G, Bouzat C.

Mol Pharmacol. 2002 Aug;62(2):406-14.

PMID:
12130694
14.

The anthelmintic pyrantel acts as a low efficacious agonist and an open-channel blocker of mammalian acetylcholine receptors.

Rayes D, De Rosa MJ, Spitzmaul G, Bouzat C.

Neuropharmacology. 2001 Aug;41(2):238-45.

PMID:
11489460
15.

The noncompetitive inhibitor quinacrine modifies the desensitization kinetics of muscle acetylcholine receptors.

Spitzmaul G, Dilger JP, Bouzat C.

Mol Pharmacol. 2001 Aug;60(2):235-43.

PMID:
11455009
16.

Amphetamine acts as a channel blocker of the acetylcholine receptor.

Spitzmaul GF, Esandi MC, Bouzat C.

Neuroreport. 1999 Jul 13;10(10):2175-81.

PMID:
10424694

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