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Items: 1 to 50 of 141

1.

Tissue-regenerative potential of the secretome of γ-irradiated peripheral blood mononuclear cells is mediated via TNFRSF1B-induced necroptosis.

Simader E, Beer L, Laggner M, Vorstandlechner V, Gugerell A, Erb M, Kalinina P, Copic D, Moser D, Spittler A, Tschachler E, Jan Ankersmit H, Mildner M.

Cell Death Dis. 2019 Sep 30;10(10):729. doi: 10.1038/s41419-019-1974-6.

2.

Phase II trial of single agent amrubicin in patients with previously treated advanced thymic malignancies.

Hellyer JA, Gubens MA, Cunanan KM, Padda SK, Burns M, Spittler AJ, Riess JW, San Pedro-Salcedo M, Ramchandran KJ, Neal JW, Wakelee HA, Loehrer PJ Sr.

Lung Cancer. 2019 Sep 18;137:71-75. doi: 10.1016/j.lungcan.2019.09.015. [Epub ahead of print]

PMID:
31557562
3.

Ropivacaine Activates Multiple Proapoptotic and Inflammatory Signaling Pathways That Might Subsume to Trigger Epidural-Related Maternal Fever.

Wohlrab P, Boehme S, Kaun C, Wojta J, Spittler A, Saleh L, Knöfler M, Markstaller K, Klein KU, Tretter V.

Anesth Analg. 2019 Sep 6. doi: 10.1213/ANE.0000000000004402. [Epub ahead of print]

PMID:
31498191
4.

The association of P2Y12 inhibitors with pro-coagulatory extracellular vesicles and microRNAs in stable coronary artery disease.

Haller PM, Stojkovic S, Piackova E, Andric T, Wisgrill L, Spittler A, Wojta J, Huber K, Jäger B.

Platelets. 2019 Aug 7:1-8. doi: 10.1080/09537104.2019.1648780. [Epub ahead of print]

PMID:
31389740
5.

Storage of human whole blood, but not isolated monocytes, preserves the distribution of monocyte subsets.

Fendl B, Weiss R, Eichhorn T, Spittler A, Fischer MB, Weber V.

Biochem Biophys Res Commun. 2019 Oct 1;517(4):709-714. doi: 10.1016/j.bbrc.2019.07.120. Epub 2019 Aug 3.

6.

Diminished secretion and function of IL-29 is associated with impaired IFN-α response of neonatal plasmacytoid dendritic cells.

Wisgrill L, Wessely I, Netzl A, Pummer L, Sadeghi K, Spittler A, Berger A, Förster-Waldl E.

J Leukoc Biol. 2019 Jun 18. doi: 10.1002/JLB.4A0518-189R. [Epub ahead of print]

PMID:
31211458
7.

The novel polyclonal Ab preparation trimodulin attenuates ex vivo endotoxin-induced immune reactions in early hyperinflammation.

Duerr C, Bacher A, de Martin A, Sachet M, Sadeghi K, Baumann S, Heinz C, Spittler A.

Innate Immun. 2019 Aug;25(6):374-388. doi: 10.1177/1753425919853333. Epub 2019 Jun 4. No abstract available.

PMID:
31165655
8.

[Comparison of visual acuity measurement with Landolt rings versus numbers].

Rohrschneider K, Spittler AR, Bach M.

Ophthalmologe. 2019 Mar 29. doi: 10.1007/s00347-019-0879-1. [Epub ahead of print] German.

PMID:
30927070
9.

Evidence for a Role of TGF-β-Activated Kinase 1 and MAP3K7 Binding Protein 3 in Peanut-Specific T-Cell Responses.

Saidova A, Bublin M, Schmidthaler K, Fajgelj V, Klinglmueller F, Spittler A, Hafner C, Szépfalusi Z, Breiteneder H, Eiwegger T.

Int Arch Allergy Immunol. 2019;179(1):10-16. doi: 10.1159/000496438. Epub 2019 Mar 20.

PMID:
30893695
10.

Clazakizumab in late antibody-mediated rejection: study protocol of a randomized controlled pilot trial.

Eskandary F, Dürr M, Budde K, Doberer K, Reindl-Schwaighofer R, Waiser J, Wahrmann M, Regele H, Spittler A, Lachmann N, Firbas C, Mühlbacher J, Bond G, Halloran PF, Chong E, Jilma B, Böhmig GA.

Trials. 2019 Jan 11;20(1):37. doi: 10.1186/s13063-018-3158-6.

11.

Differential Interaction of Platelet-Derived Extracellular Vesicles With Circulating Immune Cells: Roles of TAM Receptors, CD11b, and Phosphatidylserine.

Fendl B, Eichhorn T, Weiss R, Tripisciano C, Spittler A, Fischer MB, Weber V.

Front Immunol. 2018 Dec 11;9:2797. doi: 10.3389/fimmu.2018.02797. eCollection 2018.

12.

Immunomodulation to Prevent or Treat Neonatal Sepsis: Past, Present, and Future.

Schüller SS, Kramer BW, Villamor E, Spittler A, Berger A, Levy O.

Front Pediatr. 2018 Jul 19;6:199. doi: 10.3389/fped.2018.00199. eCollection 2018. Review.

13.

Differential Interaction of Platelet-Derived Extracellular Vesicles with Leukocyte Subsets in Human Whole Blood.

Weiss R, Gröger M, Rauscher S, Fendl B, Eichhorn T, Fischer MB, Spittler A, Weber V.

Sci Rep. 2018 Apr 26;8(1):6598. doi: 10.1038/s41598-018-25047-x.

14.

Human lactoferrin attenuates the proinflammatory response of neonatal monocyte-derived macrophages.

Wisgrill L, Wessely I, Spittler A, Förster-Waldl E, Berger A, Sadeghi K.

Clin Exp Immunol. 2018 Jun;192(3):315-324. doi: 10.1111/cei.13108. Epub 2018 Mar 12.

15.

Two Months of Therapy: A Case of Pathologic Complete Response to Chemoimmunotherapy in a Patient With Metastatic Colorectal Cancer.

Armstrong S, Al-Ghawi H, Helft P, House MG, Spittler AJ, Wu HH, Shahda S.

Clin Colorectal Cancer. 2018 Jun;17(2):e229-e232. doi: 10.1016/j.clcc.2017.12.006. Epub 2017 Dec 13. No abstract available.

PMID:
29311032
16.

Endothelial cells of extremely premature infants display impaired immune response after proinflammatory stimulation.

Wisgrill L, Muck M, Wessely I, Berger A, Spittler A, Förster-Waldl E, Sadeghi K.

Pediatr Res. 2018 Jan;83(1-1):128-134. doi: 10.1038/pr.2017.202. Epub 2017 Sep 27.

PMID:
29278644
17.

Isolation, cultivation, and characterization of human mesenchymal stem cells.

Mushahary D, Spittler A, Kasper C, Weber V, Charwat V.

Cytometry A. 2018 Jan;93(1):19-31. doi: 10.1002/cyto.a.23242. Epub 2017 Oct 26. Review.

18.

Different Potential of Extracellular Vesicles to Support Thrombin Generation: Contributions of Phosphatidylserine, Tissue Factor, and Cellular Origin.

Tripisciano C, Weiss R, Eichhorn T, Spittler A, Heuser T, Fischer MB, Weber V.

Sci Rep. 2017 Jul 26;7(1):6522. doi: 10.1038/s41598-017-03262-2.

19.

Functional and Transcriptomic Characterization of Peritoneal Immune-Modulation by Addition of Alanyl-Glutamine to Dialysis Fluid.

Herzog R, Kuster L, Becker J, Gluexam T, Pils D, Spittler A, Bhasin MK, Alper SL, Vychytil A, Aufricht C, Kratochwill K.

Sci Rep. 2017 Jul 24;7(1):6229. doi: 10.1038/s41598-017-05872-2.

20.

Expansion of BCR/ABL1+ cells requires PAK2 but not PAK1.

Edlinger L, Berger-Becvar A, Menzl I, Hoermann G, Greiner G, Grundschober E, Bago-Horvath Z, Al-Zoughbi W, Hoefler G, Brostjan C, Gille L, Moriggl R, Spittler A, Sexl V, Hoelbl-Kovacic A.

Br J Haematol. 2017 Oct;179(2):229-241. doi: 10.1111/bjh.14833. Epub 2017 Jul 14.

21.

IL-33 stimulates the release of procoagulant microvesicles from human monocytes and differentially increases tissue factor in human monocyte subsets.

Stojkovic S, Thulin Å, Hell L, Thaler B, Rauscher S, Baumgartner J, Gröger M, Ay C, Demyanets S, Neumayer C, Huk I, Spittler A, Huber K, Wojta J, Siegbahn A, Åberg M.

Thromb Haemost. 2017 Jun 28;117(7):1379-1390. doi: 10.1160/TH16-10-0784. Epub 2017 May 11. Erratum in: Thromb Haemost. 2017 Oct;117(10):2007.

PMID:
28492698
22.

Bedside Immune Monitoring: An Automated Immunoassay Platform for Quantification of Blood Biomarkers in Patient Serum within 20 Minutes.

Zirath H, Schnetz G, Glatz A, Spittler A, Redl H, Peham JR.

Anal Chem. 2017 May 2;89(9):4817-4823. doi: 10.1021/acs.analchem.6b03624. Epub 2017 Apr 19.

PMID:
28382820
23.

Pentoxifylline modulates LPS-induced hyperinflammation in monocytes of preterm infants in vitro.

Schüller SS, Wisgrill L, Herndl E, Spittler A, Förster-Waldl E, Sadeghi K, Kramer BW, Berger A.

Pediatr Res. 2017 Aug;82(2):215-225. doi: 10.1038/pr.2017.41. Epub 2017 May 24.

PMID:
28288151
24.

Potential role of platelet-leukocyte aggregation in trauma-induced coagulopathy: Ex vivo findings.

Zipperle J, Altenburger K, Ponschab M, Schlimp CJ, Spittler A, Bahrami S, Redl H, Schöchl H.

J Trauma Acute Care Surg. 2017 May;82(5):921-926. doi: 10.1097/TA.0000000000001410.

PMID:
28257393
25.

Procoagulant extracellular vesicles in amniotic fluid.

Hell L, Wisgrill L, Ay C, Spittler A, Schwameis M, Jilma B, Pabinger I, Altevogt P, Thaler J.

Transl Res. 2017 Jun;184:12-20.e1. doi: 10.1016/j.trsl.2017.01.003. Epub 2017 Feb 4.

26.

HO-1 inhibits preadipocyte proliferation and differentiation at the onset of obesity via ROS dependent activation of Akt2.

Wagner G, Lindroos-Christensen J, Einwallner E, Husa J, Zapf TC, Lipp K, Rauscher S, Gröger M, Spittler A, Loewe R, Gruber F, Duvigneau JC, Mohr T, Sutterlüty-Fall H, Klinglmüller F, Prager G, Huppertz B, Yun J, Wagner O, Esterbauer H, Bilban M.

Sci Rep. 2017 Jan 19;7:40881. doi: 10.1038/srep40881.

27.

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity.

Li J, Casteels T, Frogne T, Ingvorsen C, Honoré C, Courtney M, Huber KVM, Schmitner N, Kimmel RA, Romanov RA, Sturtzel C, Lardeau CH, Klughammer J, Farlik M, Sdelci S, Vieira A, Avolio F, Briand F, Baburin I, Májek P, Pauler FM, Penz T, Stukalov A, Gridling M, Parapatics K, Barbieux C, Berishvili E, Spittler A, Colinge J, Bennett KL, Hering S, Sulpice T, Bock C, Distel M, Harkany T, Meyer D, Superti-Furga G, Collombat P, Hecksher-Sørensen J, Kubicek S.

Cell. 2017 Jan 12;168(1-2):86-100.e15. doi: 10.1016/j.cell.2016.11.010. Epub 2016 Dec 1.

28.

GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes.

Sadeghi K, Wisgrill L, Wessely I, Diesner SC, Schüller S, Dürr C, Heinle A, Sachet M, Pollak A, Förster-Waldl E, Spittler A.

PLoS One. 2016 Oct 3;11(10):e0162667. doi: 10.1371/journal.pone.0162667. eCollection 2016.

29.

Folate Receptor β Regulates Integrin CD11b/CD18 Adhesion of a Macrophage Subset to Collagen.

Machacek C, Supper V, Leksa V, Mitulovic G, Spittler A, Drbal K, Suchanek M, Ohradanova-Repic A, Stockinger H.

J Immunol. 2016 Sep 15;197(6):2229-38. doi: 10.4049/jimmunol.1501878. Epub 2016 Aug 17.

30.

Chemotherapy of colorectal liver metastases induces a rapid rise in intermediate blood monocytes which predicts treatment response.

Schauer D, Starlinger P, Alidzanovic L, Zajc P, Maier T, Feldman A, Padickakudy R, Buchberger E, Elleder V, Spittler A, Stift J, Pop L, Gruenberger B, Gruenberger T, Brostjan C.

Oncoimmunology. 2016 Mar 22;5(6):e1160185. doi: 10.1080/2162402X.2016.1160185. eCollection 2016 Jun.

31.

Characterization of extracellular vesicles in whole blood: Influence of pre-analytical parameters and visualization of vesicle-cell interactions using imaging flow cytometry.

Fendl B, Weiss R, Fischer MB, Spittler A, Weber V.

Biochem Biophys Res Commun. 2016 Sep 9;478(1):168-173. doi: 10.1016/j.bbrc.2016.07.073. Epub 2016 Jul 19.

PMID:
27444383
32.

Peripheral blood microvesicles secretion is influenced by storage time, temperature, and anticoagulants.

Wisgrill L, Lamm C, Hartmann J, Preißing F, Dragosits K, Bee A, Hell L, Thaler J, Ay C, Pabinger I, Berger A, Spittler A.

Cytometry A. 2016 Jul;89(7):663-72. doi: 10.1002/cyto.a.22892.

33.

Phase I Study of Lenalidomide and Sorafenib in Patients With Advanced Hepatocellular Carcinoma.

Shahda S, Loehrer PJ, Clark RS, Spittler AJ, Althouse SK, Chiorean EG.

Oncologist. 2016 Jun;21(6):664-5. doi: 10.1634/theoncologist.2016-0071. Epub 2016 Jun 2.

34.

Effect of hemoadsorption during cardiopulmonary bypass surgery - a blinded, randomized, controlled pilot study using a novel adsorbent.

Bernardi MH, Rinoesl H, Dragosits K, Ristl R, Hoffelner F, Opfermann P, Lamm C, Preißing F, Wiedemann D, Hiesmayr MJ, Spittler A.

Crit Care. 2016 Apr 9;20:96. doi: 10.1186/s13054-016-1270-0.

35.

The TLR-specific adjuvants R-848 and CpG-B endorse the immunological reaction of neonatal antigen-presenting cells.

Schüller S, Wisgrill L, Sadeghi K, Gindl E, Helmer H, Husslein P, Berger A, Spittler A, Förster-Waldl E.

Pediatr Res. 2016 Aug;80(2):311-8. doi: 10.1038/pr.2016.71. Epub 2016 Apr 8.

PMID:
27057737
36.

Reduced TNF-α response in preterm neonates is associated with impaired nonclassic monocyte function.

Wisgrill L, Groschopf A, Herndl E, Sadeghi K, Spittler A, Berger A, Förster-Waldl E.

J Leukoc Biol. 2016 Sep;100(3):607-12. doi: 10.1189/jlb.4A0116-001RR. Epub 2016 Mar 10.

PMID:
26965638
37.

A compact and integrated immunoassay with on-chip dispensing and magnetic particle handling.

Zirath H, Peham JR, Schnetz G, Coll A, Brandhoff L, Spittler A, Vellekoop MJ, Redl H.

Biomed Microdevices. 2016 Feb;18(1):16. doi: 10.1007/s10544-016-0045-3.

PMID:
26842948
38.

Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.

Li J, Klughammer J, Farlik M, Penz T, Spittler A, Barbieux C, Berishvili E, Bock C, Kubicek S.

EMBO Rep. 2016 Feb;17(2):178-87. doi: 10.15252/embr.201540946. Epub 2015 Dec 21.

39.

Release and cellular origin of extracellular vesicles during circulation of whole blood over adsorbent polymers for lipid apheresis.

Weiss R, Eichhorn T, Spittler A, Mičušík M, Fischer MB, Weber V.

J Biomed Mater Res B Appl Biomater. 2017 Apr;105(3):636-646. doi: 10.1002/jbm.b.33588. Epub 2015 Dec 16.

PMID:
26671881
40.

EVI1 promotes tumor growth via transcriptional repression of MS4A3.

Heller G, Rommer A, Steinleitner K, Etzler J, Hackl H, Heffeter P, Tomasich E, Filipits M, Steinmetz B, Topakian T, Klingenbrunner S, Ziegler B, Spittler A, Zöchbauer-Müller S, Berger W, Wieser R.

J Hematol Oncol. 2015 Mar 21;8:28. doi: 10.1186/s13045-015-0124-6.

41.

Ocular metastasis of colorectal cancer: An uncommon presentation of a common malignancy.

Khawaja MR, Minturn JT, Spittler AJ, Chiorean EG.

Hematol Oncol Stem Cell Ther. 2015 Dec;8(4):176-80. doi: 10.1016/j.hemonc.2015.02.002. Epub 2015 Mar 10.

42.

Sunitinib in patients with chemotherapy-refractory thymoma and thymic carcinoma: an open-label phase 2 trial.

Thomas A, Rajan A, Berman A, Tomita Y, Brzezniak C, Lee MJ, Lee S, Ling A, Spittler AJ, Carter CA, Guha U, Wang Y, Szabo E, Meltzer P, Steinberg SM, Trepel JB, Loehrer PJ, Giaccone G.

Lancet Oncol. 2015 Feb;16(2):177-86. doi: 10.1016/S1470-2045(14)71181-7. Epub 2015 Jan 13. Erratum in: Lancet Oncol. 2015 Mar;16(3):e105.

43.

Molecular and cellular effects of in vitro shockwave treatment on lymphatic endothelial cells.

Rohringer S, Holnthoner W, Hackl M, Weihs AM, Rünzler D, Skalicky S, Karbiener M, Scheideler M, Pröll J, Gabriel C, Schweighofer B, Gröger M, Spittler A, Grillari J, Redl H.

PLoS One. 2014 Dec 11;9(12):e114806. doi: 10.1371/journal.pone.0114806. eCollection 2014.

44.

The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid.

Steinmetz B, Hackl H, Slabáková E, Schwarzinger I, Smějová M, Spittler A, Arbesu I, Shehata M, Souček K, Wieser R.

Cell Cycle. 2014;13(18):2931-43. doi: 10.4161/15384101.2014.946869. Erratum in: Cell Cycle. 2015;14(11):1759.

45.

HIF1α Regulates mTOR Signaling and Viability of Prostate Cancer Stem Cells.

Marhold M, Tomasich E, El-Gazzar A, Heller G, Spittler A, Horvat R, Krainer M, Horak P.

Mol Cancer Res. 2015 Mar;13(3):556-64. doi: 10.1158/1541-7786.MCR-14-0153-T. Epub 2014 Oct 27.

46.

Hematopoietic stem cells in neonates: any differences between very preterm and term neonates?

Wisgrill L, Schüller S, Bammer M, Berger A, Pollak A, Radke TF, Kögler G, Spittler A, Helmer H, Husslein P, Gortner L.

PLoS One. 2014 Sep 2;9(9):e106717. doi: 10.1371/journal.pone.0106717. eCollection 2014.

47.

Serum-dependent processing of late apoptotic cells for enhanced efferocytosis.

Liang YY, Arnold T, Michlmayr A, Rainprecht D, Perticevic B, Spittler A, Oehler R.

Cell Death Dis. 2014 May 29;5:e1264. doi: 10.1038/cddis.2014.210.

48.

Thrombocyte adhesion and release of extracellular microvesicles correlate with surface morphology of adsorbent polymers for lipid apheresis.

Weiss R, Spittler A, Schmitz G, Fischer MB, Weber V.

Biomacromolecules. 2014 Jul 14;15(7):2648-55. doi: 10.1021/bm500492r. Epub 2014 May 30.

PMID:
24844344
49.

Phase 1 pharmacogenetic and pharmacodynamic study of sorafenib with concurrent radiation therapy and gemcitabine in locally advanced unresectable pancreatic cancer.

Chiorean EG, Schneider BP, Akisik FM, Perkins SM, Anderson S, Johnson CS, DeWitt J, Helft P, Clark R, Johnston EL, Spittler AJ, Deluca J, Bu G, Shahda S, Loehrer PJ, Sandrasegaran K, Cardenes HR.

Int J Radiat Oncol Biol Phys. 2014 Jun 1;89(2):284-91. doi: 10.1016/j.ijrobp.2014.02.024. Epub 2014 Apr 11.

PMID:
24726286
50.

Macrophage-derived IL-33 is a critical factor for placental growth.

Fock V, Mairhofer M, Otti GR, Hiden U, Spittler A, Zeisler H, Fiala C, Knöfler M, Pollheimer J.

J Immunol. 2013 Oct 1;191(7):3734-43. doi: 10.4049/jimmunol.1300490. Epub 2013 Aug 30.

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