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Items: 1 to 50 of 145

1.

Hitchhiker's guide to the red blood cell storage lesion.

Thomas T, Spitalnik SL.

Blood Transfus. 2019 Jan;17(1):1-3. doi: 10.2450/2019.0257-18. No abstract available.

2.

Translating red cell "omics" into new perspectives in transfusion medicine: mining the gems in the data mountains.

Spitalnik SL, Devine DV.

Transfusion. 2019 Jan;59(1):2-5. doi: 10.1111/trf.15066. No abstract available.

PMID:
30615814
3.

Increased erythrophagocytosis induces ferroptosis in red pulp macrophages in a mouse model of transfusion.

Youssef LA, Rebbaa A, Pampou S, Weisberg SP, Stockwell BR, Hod EA, Spitalnik SL.

Blood. 2018 Jun 7;131(23):2581-2593. doi: 10.1182/blood-2017-12-822619. Epub 2018 Apr 17.

PMID:
29666112
4.

Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage.

Nemkov T, Sun K, Reisz JA, Song A, Yoshida T, Dunham A, Wither MJ, Francis RO, Roach RC, Dzieciatkowska M, Rogers SC, Doctor A, Kriebardis A, Antonelou M, Papassideri I, Young CT, Thomas TA, Hansen KC, Spitalnik SL, Xia Y, Zimring JC, Hod EA, D'Alessandro A.

Haematologica. 2018 Feb;103(2):361-372. doi: 10.3324/haematol.2017.178608. Epub 2017 Oct 27.

5.

Iron: a double-edged sword.

Youssef LA, Spitalnik SL.

Transfusion. 2017 Oct;57(10):2293-2297. doi: 10.1111/trf.14296. No abstract available.

6.

Transfusion-related immunomodulation: a reappraisal.

Youssef LA, Spitalnik SL.

Curr Opin Hematol. 2017 Nov;24(6):551-557. doi: 10.1097/MOH.0000000000000376. Review.

7.

Red Blood Cell Storage Lesion-Induced Adverse Effects: More Smoke; Is There Fire?

Hod EA, Francis RO, Spitalnik SL.

Anesth Analg. 2017 Jun;124(6):1752-1754. doi: 10.1213/ANE.0000000000001879. No abstract available.

8.

Iron-deficient erythropoiesis in blood donors and red blood cell recovery after transfusion: initial studies with a mouse model.

Bandyopadhyay S, Brittenham GM, Francis RO, Zimring JC, Hod EA, Spitalnik SL.

Blood Transfus. 2017 Mar;15(2):158-164. doi: 10.2450/2017.0349-16.

9.

The controversy over the age of blood: what do the clinical trials really teach us?

Belpulsi D, Spitalnik SL, Hod EA.

Blood Transfus. 2017 Mar;15(2):112-115. doi: 10.2450/2017.0328-16. Review.

10.

Large retrospective effects, clear differences in animals, and multiple negative randomised controlled trials: this is exactly how it is supposed to work.

Zimring JC, Spitalnik SL.

Blood Transfus. 2017 Mar;15(2):104-106. doi: 10.2450/2017.0307-16. No abstract available.

11.

Prolonged red cell storage before transfusion increases extravascular hemolysis.

Rapido F, Brittenham GM, Bandyopadhyay S, La Carpia F, L'Acqua C, McMahon DJ, Rebbaa A, Wojczyk BS, Netterwald J, Wang H, Schwartz J, Eisenberger A, Soffing M, Yeh R, Divgi C, Ginzburg YZ, Shaz BH, Sheth S, Francis RO, Spitalnik SL, Hod EA.

J Clin Invest. 2017 Jan 3;127(1):375-382. doi: 10.1172/JCI90837. Epub 2016 Dec 12.

12.

Disposal of iron by a mutant form of lipocalin 2.

Barasch J, Hollmen M, Deng R, Hod EA, Rupert PB, Abergel RJ, Allred BE, Xu K, Darrah SF, Tekabe Y, Perlstein A, Wax R, Bruck E, Stauber J, Corbin KA, Buchen C, Slavkovich V, Graziano J, Spitalnik SL, Bao G, Strong RK, Qiu A.

Nat Commun. 2016 Oct 31;7:12973. doi: 10.1038/ncomms12973.

13.

Scientific advances: Fallacy of perfection harms peer review.

Zimring JC, Spitalnik SL.

Nature. 2016 Sep 1;537(7618):34. doi: 10.1038/537034a. No abstract available.

PMID:
27582209
14.

Red blood cell components: Meeting the quantitative and qualitative transfusion needs.

Francis RO, Spitalnik SL.

Presse Med. 2016 Jul-Aug;45(7-8 Pt 2):e281-8. doi: 10.1016/j.lpm.2016.06.019. Epub 2016 Jul 27. Review.

PMID:
27476016
15.

The Nlrp3 Inflammasome Does Not Regulate Alloimmunization to Transfused Red Blood Cells in Mice.

Gibb DR, Calabro S, Liu D, Tormey CA, Spitalnik SL, Zimring JC, Hendrickson JE, Hod EA, Eisenbarth SC.

EBioMedicine. 2016 Jul;9:77-86. doi: 10.1016/j.ebiom.2016.06.008. Epub 2016 Jun 16.

16.

Bridging channel dendritic cells induce immunity to transfused red blood cells.

Calabro S, Gallman A, Gowthaman U, Liu D, Chen P, Liu J, Krishnaswamy JK, Nascimento MS, Xu L, Patel SR, Williams A, Tormey CA, Hod EA, Spitalnik SL, Zimring JC, Hendrickson JE, Stowell SR, Eisenbarth SC.

J Exp Med. 2016 May 30;213(6):887-96. doi: 10.1084/jem.20151720. Epub 2016 May 16.

17.

Lost in translation: signal and frequency amplification in animal modeling.

Zimring JC, Spitalnik SL, Odem-Davis K.

Transfusion. 2016 Mar;56(3):773-4. doi: 10.1111/trf.13457. No abstract available.

PMID:
26954453
18.

2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium.

Spitalnik SL, Triulzi D, Devine DV, Dzik WH, Eder AF, Gernsheimer T, Josephson CD, Kor DJ, Luban NL, Roubinian NH, Mondoro T, Welniak LA, Zou S, Glynn S; State of the Science in Transfusion Medicine Working Groups.

Transfusion. 2015 Sep;55(9):2282-90. doi: 10.1111/trf.13250. Epub 2015 Aug 10.

19.

G6PD Deficiency in an HIV Clinic Setting in the Dominican Republic.

Xu JZ, Francis RO, Lerebours Nadal LE, Shirazi M, Jobanputra V, Hod EA, Jhang JS, Stotler BA, Spitalnik SL, Nicholas SW.

Am J Trop Med Hyg. 2015 Oct;93(4):722-9. doi: 10.4269/ajtmh.14-0295. Epub 2015 Aug 3.

20.

Red blood cell transfusion is associated with increased hemolysis and an acute phase response in a subset of critically ill children.

L'Acqua C, Bandyopadhyay S, Francis RO, McMahon DJ, Nellis M, Sheth S, Kernie SG, Brittenham GM, Spitalnik SL, Hod EA.

Am J Hematol. 2015 Oct;90(10):915-20. doi: 10.1002/ajh.24119.

21.

Analysis of 24-h recovery of transfused stored RBCs in recipient mice of distinct genetic backgrounds.

Waterman HR, Kapp LM, Howie HL, Hod EA, Spitalnik SL, Zimring JC.

Vox Sang. 2015 Aug;109(2):148-54. doi: 10.1111/vox.12270. Epub 2015 Jun 5.

PMID:
26053689
22.

CD59 signaling and membrane pores drive Syk-dependent erythrocyte necroptosis.

LaRocca TJ, Stivison EA, Mal-Sarkar T, Hooven TA, Hod EA, Spitalnik SL, Ratner AJ.

Cell Death Dis. 2015 May 28;6:e1773. doi: 10.1038/cddis.2015.135.

23.

Pathobiology of transfusion reactions.

Zimring JC, Spitalnik SL.

Annu Rev Pathol. 2015;10:83-110. doi: 10.1146/annurev-pathol-012414-040318. Review.

PMID:
25621658
24.

Stored red blood cell transfusions: iron, inflammation, immunity, and infection.

Spitalnik SL.

Transfusion. 2014 Oct;54(10):2365-71. doi: 10.1111/trf.12848. Epub 2014 Sep 4. Review.

25.

Human-specific bacterial pore-forming toxins induce programmed necrosis in erythrocytes.

LaRocca TJ, Stivison EA, Hod EA, Spitalnik SL, Cowan PJ, Randis TM, Ratner AJ.

MBio. 2014 Aug 26;5(5):e01251-14. doi: 10.1128/mBio.01251-14.

26.

Macrophages clear refrigerator storage-damaged red blood cells and subsequently secrete cytokines in vivo, but not in vitro, in a murine model.

Wojczyk BS, Kim N, Bandyopadhyay S, Francis RO, Zimring JC, Hod EA, Spitalnik SL.

Transfusion. 2014 Dec;54(12):3186-97. doi: 10.1111/trf.12755. Epub 2014 Jul 20.

27.

Transfusion of stored blood impairs host defenses against Gram-negative pathogens in mice.

Prestia K, Bandyopadhyay S, Slate A, Francis RO, Francis KP, Spitalnik SL, Fidock DA, Brittenham GM, Hod EA.

Transfusion. 2014 Nov;54(11):2842-51. doi: 10.1111/trf.12712. Epub 2014 May 19.

28.

Identification of a family of four UDP-polypeptide N-acetylgalactosaminyl transferases in Cryptosporidium species.

Bhat N, Wojczyk BS, DeCicco M, Castrodad C, Spitalnik SL, Ward HD.

Mol Biochem Parasitol. 2013 Sep;191(1):24-7. doi: 10.1016/j.molbiopara.2013.08.002. Epub 2013 Aug 13.

29.

Glucose-6-phosphate dehydrogenase deficiency in transfusion medicine: the unknown risks.

Francis RO, Jhang JS, Pham HP, Hod EA, Zimring JC, Spitalnik SL.

Vox Sang. 2013 Nov;105(4):271-82. doi: 10.1111/vox.12068. Epub 2013 Jul 2. Review.

30.

Strain-specific red blood cell storage, metabolism, and eicosanoid generation in a mouse model.

Zimring JC, Smith N, Stowell SR, Johnsen JM, Bell LN, Francis RO, Hod EA, Hendrickson JE, Roback JD, Spitalnik SL.

Transfusion. 2014 Jan;54(1):137-48. doi: 10.1111/trf.12264. Epub 2013 May 30.

31.

Effect of dietary iron on fetal growth in pregnant mice.

Hubbard AC, Bandyopadhyay S, Wojczyk BS, Spitalnik SL, Hod EA, Prestia KA.

Comp Med. 2013 Apr;63(2):127-35.

32.

On the appropriate use and interpretation of animal models in transfusion medicine research.

Zimring JC, Spitalnik SL.

Transfusion. 2013 Oct;53(10):2334-9. doi: 10.1111/trf.12131. Epub 2013 Feb 26. No abstract available.

PMID:
23441757
33.

Resistance of a subset of red blood cells to clearance by antibodies in a mouse model of incompatible transfusion.

Liepkalns JS, Cadwell CM, Stowell SR, Hod EA, Spitalnik SL, Zimring JC.

Transfusion. 2013 Jun;53(6):1319-27. doi: 10.1111/j.1537-2995.2012.03910.x. Epub 2012 Oct 3.

PMID:
23033973
34.

Frequency of glucose-6-phosphate dehydrogenase-deficient red blood cell units in a metropolitan transfusion service.

Francis RO, Jhang J, Hendrickson JE, Zimring JC, Hod EA, Spitalnik SL.

Transfusion. 2013 Mar;53(3):606-11. doi: 10.1111/j.1537-2995.2012.03765.x. Epub 2012 Jun 28.

35.

Stored red blood cell transfusions: Iron, inflammation, immunity, and infection.

Hod EA, Spitalnik SL.

Transfus Clin Biol. 2012 Jun;19(3):84-9. doi: 10.1016/j.tracli.2012.04.001. Epub 2012 Jun 7. Review.

PMID:
22682673
36.

Biphasic clearance of incompatible red blood cells through a novel mechanism requiring neither complement nor Fcγ receptors in a murine model.

Liepkalns JS, Hod EA, Stowell SR, Cadwell CM, Spitalnik SL, Zimring JC.

Transfusion. 2012 Dec;52(12):2631-45. doi: 10.1111/j.1537-2995.2012.03647.x. Epub 2012 Apr 15.

PMID:
22502635
37.

Transfusion in the absence of inflammation induces antigen-specific tolerance to murine RBCs.

Smith NH, Hod EA, Spitalnik SL, Zimring JC, Hendrickson JE.

Blood. 2012 Feb 9;119(6):1566-9. doi: 10.1182/blood-2011-09-382655. Epub 2011 Nov 10. Erratum in: Blood. 2014 Mar 27;123(13):1182.

38.

Transfusion of human volunteers with older, stored red blood cells produces extravascular hemolysis and circulating non-transferrin-bound iron.

Hod EA, Brittenham GM, Billote GB, Francis RO, Ginzburg YZ, Hendrickson JE, Jhang J, Schwartz J, Sharma S, Sheth S, Sireci AN, Stephens HL, Stotler BA, Wojczyk BS, Zimring JC, Spitalnik SL.

Blood. 2011 Dec 15;118(25):6675-82. doi: 10.1182/blood-2011-08-371849. Epub 2011 Oct 20.

39.

Alloimmunization to transfused HOD red blood cells is not increased in mice with sickle cell disease.

Hendrickson JE, Hod EA, Perry JR, Ghosh S, Chappa P, Adisa O, Kean LS, Ofori-Acquah SF, Archer DR, Spitalnik SL, Zimring JC.

Transfusion. 2012 Feb;52(2):231-40. doi: 10.1111/j.1537-2995.2011.03255.x. Epub 2011 Jul 25.

40.

Discriminative accuracy of novel and traditional biomarkers in children with suspected appendicitis adjusted for duration of abdominal pain.

Kharbanda AB, Cosme Y, Liu K, Spitalnik SL, Dayan PS.

Acad Emerg Med. 2011 Jun;18(6):567-74. doi: 10.1111/j.1553-2712.2011.01095.x.

41.

Transfusion requirements in obstetric patients with placenta accreta.

Stotler B, Padmanabhan A, Devine P, Wright J, Spitalnik SL, Schwartz J.

Transfusion. 2011 Dec;51(12):2627-33. doi: 10.1111/j.1537-2995.2011.03205.x. Epub 2011 Jun 9.

PMID:
21658046
42.

Transfusion of fresh murine red blood cells reverses adverse effects of older stored red blood cells.

Hendrickson JE, Hod EA, Hudson KE, Spitalnik SL, Zimring JC.

Transfusion. 2011 Dec;51(12):2695-702. doi: 10.1111/j.1537-2995.2011.03197.x. Epub 2011 Jun 3.

43.

Rapid clearance of transfused murine red blood cells is associated with recipient cytokine storm and enhanced alloimmunogenicity.

Hendrickson JE, Hod EA, Cadwell CM, Eisenbarth SC, Spiegel DA, Tormey CA, Spitalnik SL, Zimring JC.

Transfusion. 2011 Nov;51(11):2445-54. doi: 10.1111/j.1537-2995.2011.03162.x. Epub 2011 May 13.

44.

Harmful effects of transfusion of older stored red blood cells: iron and inflammation.

Hod EA, Spitalnik SL.

Transfusion. 2011 Apr;51(4):881-5. doi: 10.1111/j.1537-2995.2011.03096.x.

PMID:
21496050
45.

CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions.

Jang JE, Hod EA, Spitalnik SL, Frenette PS.

J Clin Invest. 2011 Apr;121(4):1397-401. doi: 10.1172/JCI45336. Epub 2011 Mar 7.

46.

Current problems and future directions of transfusion-induced alloimmunization: summary of an NHLBI working group.

Zimring JC, Welniak L, Semple JW, Ness PM, Slichter SJ, Spitalnik SL; NHLBI Alloimmunization Working Group.

Transfusion. 2011 Feb;51(2):435-41. doi: 10.1111/j.1537-2995.2010.03024.x. Epub 2011 Jan 20.

PMID:
21251006
47.

Use of mouse models to study the mechanisms and consequences of RBC clearance.

Hod EA, Arinsburg SA, Francis RO, Hendrickson JE, Zimring JC, Spitalnik SL.

Vox Sang. 2010 Aug 1;99(2):99-111. doi: 10.1111/j.1423-0410.2010.01327.x. Epub 2010 Mar 21. Review.

48.

Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation.

Hod EA, Zhang N, Sokol SA, Wojczyk BS, Francis RO, Ansaldi D, Francis KP, Della-Latta P, Whittier S, Sheth S, Hendrickson JE, Zimring JC, Brittenham GM, Spitalnik SL.

Blood. 2010 May 27;115(21):4284-92. doi: 10.1182/blood-2009-10-245001. Epub 2010 Mar 18.

49.

Educating medical students in laboratory medicine: a proposed curriculum.

Smith BR, Aguero-Rosenfeld M, Anastasi J, Baron B, Berg A, Bock JL, Campbell S, Crookston KP, Fitzgerald R, Fung M, Haspel R, Howe JG, Jhang J, Kamoun M, Koethe S, Krasowski MD, Landry ML, Marques MB, Rinder HM, Roberts W, Schreiber WE, Spitalnik SL, Tormey CA, Wolf P, Wu YY; Academy of Clinical Laboratory Physicians and Scientists.

Am J Clin Pathol. 2010 Apr;133(4):533-42. doi: 10.1309/AJCPQCT94SFERLNI.

PMID:
20231605
50.

Storage of murine red blood cells enhances alloantibody responses to an erythroid-specific model antigen.

Hendrickson JE, Hod EA, Spitalnik SL, Hillyer CD, Zimring JC.

Transfusion. 2010 Mar;50(3):642-8. doi: 10.1111/j.1537-2995.2009.02481.x. Epub 2009 Nov 9.

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