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Items: 20

1.

Analysis of the AHR gene proximal promoter GGGGC-repeat polymorphism in lung, breast, and colon cancer.

Spink BC, Bloom MS, Wu S, Sell S, Schneider E, Ding X, Spink DC.

Toxicol Appl Pharmacol. 2015 Jan 1;282(1):30-41. doi: 10.1016/j.taap.2014.10.017. Epub 2014 Nov 4.

2.

Genetic and epigenetic regulation of AHR gene expression in MCF-7 breast cancer cells: role of the proximal promoter GC-rich region.

Englert NA, Turesky RJ, Han W, Bessette EE, Spivack SD, Caggana M, Spink DC, Spink BC.

Biochem Pharmacol. 2012 Sep 1;84(5):722-35. doi: 10.1016/j.bcp.2012.06.013. Epub 2012 Jun 21.

3.

Expression of the aryl hydrocarbon receptor is not required for the proliferation, migration, invasion, or estrogen-dependent tumorigenesis of MCF-7 breast cancer cells.

Spink BC, Bennett JA, Lostritto N, Cole JR, Spink DC.

Mol Carcinog. 2013 Jul;52(7):544-54. doi: 10.1002/mc.21889. Epub 2012 Mar 2.

4.

Persistent and non-persistent changes in gene expression result from long-term estrogen exposure of MCF-7 breast cancer cells.

Englert NA, Spink BC, Spink DC.

J Steroid Biochem Mol Biol. 2011 Feb;123(3-5):140-50. doi: 10.1016/j.jsbmb.2010.12.010. Epub 2010 Dec 23.

PMID:
21185374
5.

Long-term estrogen exposure promotes carcinogen bioactivation, induces persistent changes in gene expression, and enhances the tumorigenicity of MCF-7 human breast cancer cells.

Spink BC, Bennett JA, Pentecost BT, Lostritto N, Englert NA, Benn GK, Goodenough AK, Turesky RJ, Spink DC.

Toxicol Appl Pharmacol. 2009 Nov 1;240(3):355-66. doi: 10.1016/j.taap.2009.07.013. Epub 2009 Jul 18.

6.

Induction of CYP1A1 and CYP1B1 by benzo(k)fluoranthene and benzo(a)pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH metabolites.

Spink DC, Wu SJ, Spink BC, Hussain MM, Vakharia DD, Pentecost BT, Kaminsky LS.

Toxicol Appl Pharmacol. 2008 Feb 1;226(3):213-24. Epub 2007 Sep 5.

7.

Inhibition of MCF-7 breast cancer cell proliferation by MCF-10A breast epithelial cells in coculture.

Spink BC, Cole RW, Katz BH, Gierthy JF, Bradley LM, Spink DC.

Cell Biol Int. 2006 Mar;30(3):227-38. Epub 2006 Jan 19.

PMID:
16427788
8.

Transient induction of cytochromes P450 1A1 and 1B1 in MCF-7 human breast cancer cells by indirubin.

Spink BC, Hussain MM, Katz BH, Eisele L, Spink DC.

Biochem Pharmacol. 2003 Dec 15;66(12):2313-21.

PMID:
14637189
9.

Estrogen regulates Ah responsiveness in MCF-7 breast cancer cells.

Spink DC, Katz BH, Hussain MM, Pentecost BT, Cao Z, Spink BC.

Carcinogenesis. 2003 Dec;24(12):1941-50. Epub 2003 Sep 11.

PMID:
12970067
11.

Induction of cytochrome P450 1B1 in MDA-MB-231 human breast cancer cells by non-ortho-substituted polychlorinated biphenyls.

Spink BC, Pang S, Pentecost BT, Spink DC.

Toxicol In Vitro. 2002 Dec;16(6):695-704.

PMID:
12423652
12.

Induction of CYP1A1 and CYP1B1 in T-47D human breast cancer cells by benzo[a]pyrene is diminished by arsenite.

Spink DC, Katz BH, Hussain MM, Spink BC, Wu SJ, Liu N, Pause R, Kaminsky LS.

Drug Metab Dispos. 2002 Mar;30(3):262-9.

PMID:
11854143
13.

NADPH- and hydroperoxide-supported 17beta-estradiol hydroxylation catalyzed by a variant form (432L, 453S) of human cytochrome P450 1B1.

Spink DC, Spink BC, Zhuo X, Hussain MM, Gierthy JF, Ding X.

J Steroid Biochem Mol Biol. 2000 Sep;74(1-2):11-8.

PMID:
11074351
14.

SULT1A1 catalyzes 2-methoxyestradiol sulfonation in MCF-7 breast cancer cells.

Spink BC, Katz BH, Hussain MM, Pang S, Connor SP, Aldous KM, Gierthy JF, Spink DC.

Carcinogenesis. 2000 Nov;21(11):1947-57.

PMID:
11062153
15.

Growth inhibition of MCF-7 cells by estrogen is dependent upon a serum factor.

Tanji M, Katz BH, Spink BC, Carpenter DO.

Anticancer Res. 2000 Jul-Aug;20(4):2779-83.

PMID:
10953357
16.
17.

Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells.

Spink DC, Spink BC, Cao JQ, DePasquale JA, Pentecost BT, Fasco MJ, Li Y, Sutter TR.

Carcinogenesis. 1998 Feb;19(2):291-8.

PMID:
9498279
18.

Induction of cytochrome P450 1B1 and catechol estrogen metabolism in ACHN human renal adenocarcinoma cells.

Spink DC, Spink BC, Cao JQ, Gierthy JF, Hayes CL, Li Y, Sutter TR.

J Steroid Biochem Mol Biol. 1997 Jun;62(2-3):223-32.

PMID:
9393958
19.

17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1.

Hayes CL, Spink DC, Spink BC, Cao JQ, Walker NJ, Sutter TR.

Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9776-81.

20.

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