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Items: 1 to 50 of 83

1.

Mycoplasma pneumoniae infections, 11 countries in Europe and Israel, 2011 to 2016.

Beeton ML, Zhang XS, Uldum SA, Bébéar C, Dumke R, Gullsby K, Ieven M, Loens K, Nir-Paz R, Pereyre S, Spiller OB, Chalker VJ; The ESCMID Study Group For Mycoplasma And Chlamydia Infections Esgmac Mycoplasma Pneumoniae Subgroup.

Euro Surveill. 2020 Jan;25(2). doi: 10.2807/1560-7917.ES.2020.25.2.1900112.

2.

Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice.

Pavlidis I, Spiller OB, Sammut Demarco G, MacPherson H, Howie SEM, Norman JE, Stock SJ.

Nat Commun. 2020 Jan 10;11(1):199. doi: 10.1038/s41467-019-14089-y.

3.

Mycoplasma genitalium prevalence in Welsh sexual health patients: Low antimicrobial resistance markers and no association of symptoms to bacterial load.

Spiller OB, Rees CL, Morris DJ, Davies RL, Jones LC.

Microb Pathog. 2019 Nov 19;139:103872. doi: 10.1016/j.micpath.2019.103872. [Epub ahead of print]

PMID:
31756372
4.

Detrimental Effects of an Inhaled Phosphodiesterase-4 Inhibitor on Lung Inflammation in Ventilated Preterm Lambs Exposed to Chorioamnionitis Are Dose Dependent.

Hütten MC, Fehrholz M, Konrad FM, Ophelders D, Kleintjes C, Ottensmeier B, Spiller OB, Glaser K, Kramer BW, Kunzmann S.

J Aerosol Med Pulm Drug Deliv. 2019 Dec;32(6):396-404. doi: 10.1089/jamp.2019.1528. Epub 2019 Oct 1.

PMID:
31573405
5.

Protection of the Ovine Fetal Gut against Ureaplasma-Induced Chorioamnionitis: A Potential Role for Plant Sterols.

van Gorp C, de Lange IH, Spiller OB, Dewez F, Cillero Pastor B, Heeren RMA, Kessels L, Kloosterboer N, van Gemert WG, Beeton ML, Stock SJ, Jobe AH, Payne MS, Kemp MW, Zimmermann LJ, Kramer BW, Plat J, Wolfs TGAM.

Nutrients. 2019 Apr 27;11(5). pii: E968. doi: 10.3390/nu11050968.

6.

Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms.

Yang Q, Li M, Spiller OB, Andrey DO, Hinchliffe P, Li H, MacLean C, Niumsup P, Powell L, Pritchard M, Papkou A, Shen Y, Portal E, Sands K, Spencer J, Tansawai U, Thomas D, Wang S, Wang Y, Shen J, Walsh T.

Nat Commun. 2017 Dec 12;8(1):2054. doi: 10.1038/s41467-017-02149-0.

7.

The Paradoxical Effects of Chronic Intra-Amniotic Ureaplasma parvum Exposure on Ovine Fetal Brain Development.

Gussenhoven R, Ophelders DRMG, Kemp MW, Payne MS, Spiller OB, Beeton ML, Stock SJ, Cillero-Pastor B, Barré FPY, Heeren RMA, Kessels L, Stevens B, Rutten BP, Kallapur SG, Jobe AH, Kramer BW, Wolfs TGAM.

Dev Neurosci. 2017;39(6):472-486. doi: 10.1159/000479021. Epub 2017 Aug 29.

8.

Pulmonary vascular changes in extremely preterm sheep after intra-amniotic exposure to Ureaplasma parvum and lipopolysaccharide.

Willems MGM, Kemp MW, Fast LA, Wagemaker NMM, Janssen LEW, Newnham JP, Payne MS, Spiller OB, Kallapur SG, Jobe AH, Delhaas T, Kramer BW, Wolfs TGAM.

PLoS One. 2017 Jun 30;12(6):e0180114. doi: 10.1371/journal.pone.0180114. eCollection 2017.

9.

Emerging Pathogenic Respiratory Mycoplasma hominis Infections in Lung Transplant Patients: Time to Reassesses it's Role as a Pathogen?

Spiller OB.

EBioMedicine. 2017 May;19:8-9. doi: 10.1016/j.ebiom.2017.05.002. Epub 2017 May 3. No abstract available.

10.

Antimicrobial activity of Manuka honey against antibiotic-resistant strains of the cell wall-free bacteria Ureaplasma parvum and Ureaplasma urealyticum.

Hillitt KL, Jenkins RE, Spiller OB, Beeton ML.

Lett Appl Microbiol. 2017 Mar;64(3):198-202. doi: 10.1111/lam.12707. Epub 2017 Feb 1.

PMID:
27992658
11.

Genomic determination of minimum multi-locus sequence typing schemas to represent the genomic phylogeny of Mycoplasma hominis.

Jironkin A, Brown RJ, Underwood A, Chalker VJ, Spiller OB.

BMC Genomics. 2016 Nov 23;17(1):964.

12.

Foetal Ureaplasma parvum bacteraemia as a function of gestation-dependent complement insufficiency: Evidence from a sheep model of pregnancy.

Kemp MW, Ahmed S, Beeton ML, Payne MS, Saito M, Miura Y, Usuda H, Kallapur SG, Kramer BW, Stock SJ, Jobe AH, Newnham JP, Spiller OB.

Am J Reprod Immunol. 2017 Jan;77(1). doi: 10.1111/aji.12599. Epub 2016 Nov 14.

13.

Antibiotic resistance among Ureaplasma spp. isolates: cause for concern?

Beeton ML, Spiller OB.

J Antimicrob Chemother. 2017 Feb;72(2):330-337. doi: 10.1093/jac/dkw425. Epub 2016 Oct 20. Review.

PMID:
27798207
14.

Isolation of Separate Ureaplasma Species From Endotracheal Secretions of Twin Patients.

Beeton ML, Maxwell NC, Chalker VJ, Brown RJ, Aboklaish AF, Spiller OB; ESCMID Study Group for Mycoplasma Infections.

Pediatrics. 2016 Aug;138(2). pii: e20160565. doi: 10.1542/peds.2016-0565. Epub 2016 Jul 14.

15.

Intrauterine Candida albicans Infection Causes Systemic Fetal Candidiasis With Progressive Cardiac Dysfunction in a Sheep Model of Early Pregnancy.

Stock SJ, Patey O, Thilaganathan B, White S, Furfaro LL, Payne MS, Spiller OB, Noé A, Watts R, Carter S, Ireland DJ, Jobe AH, Newnham JP, Kemp MW.

Reprod Sci. 2017 Jan;24(1):77-84. doi: 10.1177/1933719116649697. Epub 2016 Sep 27.

PMID:
27217375
16.

Differential recognition of the multiple banded antigen isoforms across Ureaplasma parvum and Ureaplasma urealyticum species by monoclonal antibodies.

Aboklaish AF, Ahmed S, McAllister D, Cassell G, Zheng XT, Spiller OB.

J Microbiol Methods. 2016 Aug;127:13-19. doi: 10.1016/j.mimet.2016.05.015. Epub 2016 May 18.

PMID:
27208664
17.

Mycoplasma pneumoniae Epidemiology in England and Wales: A National Perspective.

Brown RJ, Nguipdop-Djomo P, Zhao H, Stanford E, Spiller OB, Chalker VJ.

Front Microbiol. 2016 Feb 16;7:157. doi: 10.3389/fmicb.2016.00157. eCollection 2016.

18.

Antibiotic Resistance among Clinical Ureaplasma Isolates Recovered from Neonates in England and Wales between 2007 and 2013.

Beeton ML, Chalker VJ, Jones LC, Maxwell NC, Spiller OB.

Antimicrob Agents Chemother. 2015 Oct 12;60(1):52-6. doi: 10.1128/AAC.00889-15. Print 2016 Jan.

19.

Outside-in? Acute fetal systemic inflammation in very preterm chronically catheterized sheep fetuses is not driven by cells in the fetal blood.

Kemp MW, Molloy TJ, Usuda H, Woodward E, Miura Y, Payne MS, Ireland DJ, Jobe AH, Kallapur SG, Stock SJ, Spiller OB, Newnham JP, Saito M.

Am J Obstet Gynecol. 2016 Feb;214(2):281.e1-281.e10. doi: 10.1016/j.ajog.2015.09.076. Epub 2015 Sep 25.

20.

Development of a Multilocus Sequence Typing Scheme for Molecular Typing of Mycoplasma pneumoniae.

Brown RJ, Holden MT, Spiller OB, Chalker VJ.

J Clin Microbiol. 2015 Oct;53(10):3195-203. doi: 10.1128/JCM.01301-15. Epub 2015 Jul 22.

21.

In vitro activity of solithromycin and its metabolites, CEM-214 and N-acetyl-CEM-101, against 100 clinical Ureaplasma spp. isolates compared with azithromycin.

Furfaro LL, Spiller OB, Keelan JA, Payne MS.

Int J Antimicrob Agents. 2015 Sep;46(3):319-24. doi: 10.1016/j.ijantimicag.2015.04.015. Epub 2015 Jun 19.

22.

Random insertion and gene disruption via transposon mutagenesis of Ureaplasma parvum using a mini-transposon plasmid.

Aboklaish AF, Dordet-Frisoni E, Citti C, Toleman MA, Glass JI, Spiller OB.

Int J Med Microbiol. 2014 Nov;304(8):1218-25. doi: 10.1016/j.ijmm.2014.09.003. Epub 2014 Sep 26.

23.

Maternal intravenous administration of azithromycin results in significant fetal uptake in a sheep model of second trimester pregnancy.

Kemp MW, Miura Y, Payne MS, Jobe AH, Kallapur SG, Saito M, Stock SJ, Spiller OB, Ireland DJ, Yaegashi N, Clarke M, Hahne D, Rodger J, Keelan JA, Newnham JP.

Antimicrob Agents Chemother. 2014 Nov;58(11):6581-91. doi: 10.1128/AAC.03721-14. Epub 2014 Aug 25.

24.

Comparison of complement activity in adult and preterm sheep serum.

Ahmed S, Kemp MW, Payne MS, Kallapur SG, Stock SJ, Marsh HC, Jobe AH, Newnham JP, Spiller OB.

Am J Reprod Immunol. 2015 Mar;73(3):232-41. doi: 10.1111/aji.12299. Epub 2014 Jul 21.

PMID:
25046333
25.

Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma parvum from the amniotic fluid in an ovine model of intrauterine infection.

Miura Y, Payne MS, Keelan JA, Noe A, Carter S, Watts R, Spiller OB, Jobe AH, Kallapur SG, Saito M, Stock SJ, Newnham JP, Kemp MW.

Antimicrob Agents Chemother. 2014 Sep;58(9):5413-20. doi: 10.1128/AAC.03187-14. Epub 2014 Jun 30.

26.

Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy.

Kemp MW, Miura Y, Payne MS, Watts R, Megharaj S, Jobe AH, Kallapur SG, Saito M, Spiller OB, Keelan JA, Newnham JP.

Am J Obstet Gynecol. 2014 Aug;211(2):134.e1-9. doi: 10.1016/j.ajog.2014.02.025. Epub 2014 Feb 28.

27.

High-resolution melt PCR analysis for genotyping of Ureaplasma parvum isolates directly from clinical samples.

Payne MS, Tabone T, Kemp MW, Keelan JA, Spiller OB, Newnham JP.

J Clin Microbiol. 2014 Feb;52(2):599-606. doi: 10.1128/JCM.03036-13. Epub 2013 Dec 11.

28.

Mechanism of neutrophil dysfunction: neutrophil serine proteases cleave and inactivate the C5a receptor.

van den Berg CW, Tambourgi DV, Clark HW, Hoong SJ, Spiller OB, McGreal EP.

J Immunol. 2014 Feb 15;192(4):1787-95. doi: 10.4049/jimmunol.1301920. Epub 2014 Jan 20.

29.

Association between pulmonary ureaplasma colonization and bronchopulmonary dysplasia in preterm infants: updated systematic review and meta-analysis.

Lowe J, Watkins WJ, Edwards MO, Spiller OB, Jacqz-Aigrain E, Kotecha SJ, Kotecha S.

Pediatr Infect Dis J. 2014 Jul;33(7):697-702. doi: 10.1097/INF.0000000000000239. Review.

PMID:
24445836
30.

Correction: Synergic Activation of Toll-Like Receptor (TLR) 2/6 and 9 in Response to Ureaplasma parvum & urealyticum in Human Amniotic Epithelial Cells.

Triantafilou M, De Glanville B, Aboklaish AF, Spiller OB, Kotecha S, Triantafilou K.

PLoS One. 2013 Aug 21;8(8). doi: 10.1371/annotation/1dc00176-e096-4621-9494-2d848dac8262. eCollection 2013.

31.

Synergic activation of toll-like receptor (TLR) 2/6 and 9 in response to Ureaplasma parvum & urealyticum in human amniotic epithelial cells.

Triantafilou M, De Glanville B, Aboklaish AF, Spiller OB, Kotecha S, Triantafilou K.

PLoS One. 2013 Apr 12;8(4):e61199. doi: 10.1371/journal.pone.0061199. Print 2013. Erratum in: PLoS One. 2013 Aug 21;8(8):null.

32.

Virus-host coevolution in a persistently coxsackievirus B3-infected cardiomyocyte cell line.

Pinkert S, Klingel K, Lindig V, Dörner A, Zeichhardt H, Spiller OB, Fechner H.

J Virol. 2011 Dec;85(24):13409-19. doi: 10.1128/JVI.00621-11. Epub 2011 Oct 5.

33.

Off to a slow start: under-development of the complement system in term newborns is more substantial following premature birth.

McGreal EP, Hearne K, Spiller OB.

Immunobiology. 2012 Feb;217(2):176-86. doi: 10.1016/j.imbio.2011.07.027. Epub 2011 Jul 30. Review.

PMID:
21868122
34.

Serum killing of Ureaplasma parvum shows serovar-determined susceptibility for normal individuals and common variable immuno-deficiency patients.

Beeton ML, Daha MR, El-Shanawany T, Jolles SR, Kotecha S, Spiller OB.

Immunobiology. 2012 Feb;217(2):187-94. doi: 10.1016/j.imbio.2011.07.009. Epub 2011 Jul 12.

PMID:
21802767
35.

Role of pulmonary infection in the development of chronic lung disease of prematurity.

Beeton ML, Maxwell NC, Davies PL, Nuttall D, McGreal E, Chakraborty M, Spiller OB, Kotecha S.

Eur Respir J. 2011 Jun;37(6):1424-30. doi: 10.1183/09031936.00037810. Epub 2010 Sep 30.

36.

Inactivation of IL-6 and soluble IL-6 receptor by neutrophil derived serine proteases in cystic fibrosis.

McGreal EP, Davies PL, Powell W, Rose-John S, Spiller OB, Doull I, Jones SA, Kotecha S.

Biochim Biophys Acta. 2010 Jul-Aug;1802(7-8):649-58. doi: 10.1016/j.bbadis.2010.04.005. Epub 2010 May 7.

37.

Relationship of proteinases and proteinase inhibitors with microbial presence in chronic lung disease of prematurity.

Davies PL, Spiller OB, Beeton ML, Maxwell NC, Remold-O'Donnell E, Kotecha S.

Thorax. 2010 Mar;65(3):246-51. doi: 10.1136/thx.2009.116061.

38.

Prevention of cardiac dysfunction in acute coxsackievirus B3 cardiomyopathy by inducible expression of a soluble coxsackievirus-adenovirus receptor.

Pinkert S, Westermann D, Wang X, Klingel K, Dörner A, Savvatis K, Grössl T, Krohn S, Tschöpe C, Zeichhardt H, Kotsch K, Weitmann K, Hoffmann W, Schultheiss HP, Spiller OB, Poller W, Fechner H.

Circulation. 2009 Dec 8;120(23):2358-66. doi: 10.1161/CIRCULATIONAHA.108.845339. Epub 2009 Nov 23.

PMID:
19933937
39.
40.

Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance.

Beeton ML, Chalker VJ, Maxwell NC, Kotecha S, Spiller OB.

Antimicrob Agents Chemother. 2009 May;53(5):2020-7. doi: 10.1128/AAC.01349-08. Epub 2009 Mar 9.

41.

Characterization of the complement inhibitory function of rhesus rhadinovirus complement control protein (RCP).

Okroj M, Mark L, Stokowska A, Wong SW, Rose N, Blackbourn DJ, Villoutreix BO, Spiller OB, Blom AM.

J Biol Chem. 2009 Jan 2;284(1):505-14. doi: 10.1074/jbc.M806669200. Epub 2008 Nov 6.

42.

The viral aetiology of croup and recurrent croup.

Wall SR, Wat D, Spiller OB, Gelder CM, Kotecha S, Doull IJ.

Arch Dis Child. 2009 May;94(5):359-60. doi: 10.1136/adc.2008.142984. Epub 2008 Sep 18.

PMID:
18801765
43.

Monoclonal anti-neutrophil elastase antibody characterisation: ability to block function, detect free versus serpin-complexed enzyme and stain intracellular granules.

Davies PL, Maxwell NC, Kotecha S, Spiller OB.

J Immunol Methods. 2008 Jul 31;336(2):175-82. doi: 10.1016/j.jim.2008.04.010. Epub 2008 May 9.

PMID:
18504046
44.

Growth characteristics of human adenoviruses on porcine cell lines.

Griesche N, Zikos D, Witkowski P, Nitsche A, Ellerbrok H, Spiller OB, Pauli G, Biere B.

Virology. 2008 Apr 10;373(2):400-10. doi: 10.1016/j.virol.2007.12.015. Epub 2008 Jan 11.

45.

Antibodies against Kaposi sarcoma-associated herpes virus (KSHV) complement control protein (KCP) in infected individuals.

Okroj M, Spiller OB, Korodi Z, Tedeschi R, Dillner J, Blom AM.

Vaccine. 2007 Nov 23;25(48):8102-9. Epub 2007 Oct 9.

PMID:
17964697
46.

Viral heparin-binding complement inhibitors--a recurring theme.

Blom AM, Mark L, Spiller OB.

Adv Exp Med Biol. 2007;598:105-25. Review. No abstract available.

PMID:
17892208
47.
48.

Probing the interaction between feline immunodeficiency virus and CD134 by using the novel monoclonal antibody 7D6 and the CD134 (Ox40) ligand.

Willett BJ, McMonagle EL, Logan N, Spiller OB, Schneider P, Hosie MJ.

J Virol. 2007 Sep;81(18):9665-79. Epub 2007 Jul 3.

49.

Molecular characterization of the rhesus rhadinovirus (RRV) ORF4 gene and the RRV complement control protein it encodes.

Mark L, Spiller OB, Okroj M, Chanas S, Aitken JA, Wong SW, Damania B, Blom AM, Blackbourn DJ.

J Virol. 2007 Apr;81(8):4166-76. Epub 2007 Feb 7.

50.

Kaposi's sarcoma-associated herpes virus complement control protein: KCP--complement inhibition and more.

Mark L, Spiller OB, Villoutreix BO, Blom AM.

Mol Immunol. 2007 Jan;44(1-3):11-22. Epub 2006 Aug 14. Review.

PMID:
16905191

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