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Items: 24

1.

Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool.

Jiao X, Li Z, Wang M, Katiyar S, Di Sante G, Farshchian M, South AP, Cocola C, Colombo D, Reinbold R, Zucchi I, Wu K, Tabas I, Spike BT, Pestell RG.

Stem Cell Reports. 2019 Jan 8;12(1):135-151. doi: 10.1016/j.stemcr.2018.11.010. Epub 2018 Dec 13.

2.

Single-Cell Transcriptomes Distinguish Stem Cell State Changes and Lineage Specification Programs in Early Mammary Gland Development.

Giraddi RR, Chung CY, Heinz RE, Balcioglu O, Novotny M, Trejo CL, Dravis C, Hagos BM, Mehrabad EM, Rodewald LW, Hwang JY, Fan C, Lasken R, Varley KE, Perou CM, Wahl GM, Spike BT.

Cell Rep. 2018 Aug 7;24(6):1653-1666.e7. doi: 10.1016/j.celrep.2018.07.025.

3.

Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy.

Saison-Ridinger M, DelGiorno KE, Zhang T, Kraus A, French R, Jaquish D, Tsui C, Erikson G, Spike BT, Shokhirev MN, Liddle C, Yu RT, Downes M, Evans RM, Saghatelian A, Lowy AM, Wahl GM.

PLoS One. 2017 Dec 6;12(12):e0189051. doi: 10.1371/journal.pone.0189051. eCollection 2017.

4.

Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis.

Trejo CL, Luna G, Dravis C, Spike BT, Wahl GM.

NPJ Breast Cancer. 2017 Apr 24;3:16. doi: 10.1038/s41523-017-0018-6. eCollection 2017.

5.

Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity.

Wahl GM, Spike BT.

NPJ Breast Cancer. 2017 Apr 19;3:14. doi: 10.1038/s41523-017-0012-z. eCollection 2017.

6.

Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells.

Dravis C, Spike BT, Harrell JC, Johns C, Trejo CL, Southard-Smith EM, Perou CM, Wahl GM.

Cell Rep. 2015 Sep 29;12(12):2035-48. doi: 10.1016/j.celrep.2015.08.040. Epub 2015 Sep 10.

7.

Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy.

Pfefferle AD, Spike BT, Wahl GM, Perou CM.

Breast Cancer Res Treat. 2015 Jan;149(2):425-37. doi: 10.1007/s10549-014-3262-6. Epub 2015 Jan 10.

8.

The multifaceted role of the embryonic gene Cripto-1 in cancer, stem cells and epithelial-mesenchymal transition.

Klauzinska M, Castro NP, Rangel MC, Spike BT, Gray PC, Bertolette D, Cuttitta F, Salomon D.

Semin Cancer Biol. 2014 Dec;29:51-8. doi: 10.1016/j.semcancer.2014.08.003. Epub 2014 Aug 19. Review.

9.

CRIPTO/GRP78 signaling maintains fetal and adult mammary stem cells ex vivo.

Spike BT, Kelber JA, Booker E, Kalathur M, Rodewald R, Lipianskaya J, La J, He M, Wright T, Klemke R, Wahl GM, Gray PC.

Stem Cell Reports. 2014 Apr 3;2(4):427-39. doi: 10.1016/j.stemcr.2014.02.010. eCollection 2014 Apr 8.

10.

Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts.

Pfefferle AD, Herschkowitz JI, Usary J, Harrell JC, Spike BT, Adams JR, Torres-Arzayus MI, Brown M, Egan SE, Wahl GM, Rosen JM, Perou CM.

Genome Biol. 2013 Nov 12;14(11):R125. doi: 10.1186/gb-2013-14-11-r125.

11.

Stem cells and the developing mammary gland.

Makarem M, Spike BT, Dravis C, Kannan N, Wahl GM, Eaves CJ.

J Mammary Gland Biol Neoplasia. 2013 Jun;18(2):209-19. doi: 10.1007/s10911-013-9284-6. Epub 2013 Apr 27. Review.

12.

A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer.

Spike BT, Engle DD, Lin JC, Cheung SK, La J, Wahl GM.

Cell Stem Cell. 2012 Feb 3;10(2):183-97. doi: 10.1016/j.stem.2011.12.018.

13.

p53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome.

Spike BT, Wahl GM.

Genes Cancer. 2011 Apr;2(4):404-19. doi: 10.1177/1947601911410224.

14.

Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures.

Mizuno H, Spike BT, Wahl GM, Levine AJ.

Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22745-50. doi: 10.1073/pnas.1017001108. Epub 2010 Dec 13.

15.

Elevated poly-(ADP-ribose)-polymerase activity sensitizes retinoblastoma-deficient cells to DNA damage-induced necrosis.

Liu H, Knabb JR, Spike BT, Macleod KF.

Mol Cancer Res. 2009 Jul;7(7):1099-109. doi: 10.1158/1541-7786.MCR-08-0439. Epub 2009 Jul 7.

16.

Deregulated E2f-2 underlies cell cycle and maturation defects in retinoblastoma null erythroblasts.

Dirlam A, Spike BT, Macleod KF.

Mol Cell Biol. 2007 Dec;27(24):8713-28. Epub 2007 Oct 8.

17.

Effects of hypoxia on heterotypic macrophage interactions.

Spike BT, Macleod KF.

Cell Cycle. 2007 Nov 1;6(21):2620-4. Epub 2007 Aug 13. Review.

18.

BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy.

Tracy K, Dibling BC, Spike BT, Knabb JR, Schumacker P, Macleod KF.

Mol Cell Biol. 2007 Sep;27(17):6229-42. Epub 2007 Jun 18.

19.

Hypoxic stress underlies defects in erythroblast islands in the Rb-null mouse.

Spike BT, Dibling BC, Macleod KF.

Blood. 2007 Sep 15;110(6):2173-81. Epub 2007 Jun 8.

20.

Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis.

Diwan A, Koesters AG, Odley AM, Pushkaran S, Baines CP, Spike BT, Daria D, Jegga AG, Geiger H, Aronow BJ, Molkentin JD, Macleod KF, Kalfa TA, Dorn GW 2nd.

Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6794-9. Epub 2007 Apr 9.

21.

The Rb tumor suppressor in stress responses and hematopoietic homeostasis.

Spike BT, Macleod KF.

Cell Cycle. 2005 Jan;4(1):42-5. Epub 2005 Jan 29. Review.

PMID:
15611658
22.

The Rb tumor suppressor is required for stress erythropoiesis.

Spike BT, Dirlam A, Dibling BC, Marvin J, Williams BO, Jacks T, Macleod KF.

EMBO J. 2004 Oct 27;23(21):4319-29. Epub 2004 Sep 30.

23.

Oligoclonal IgA response in the vascular wall in acute Kawasaki disease.

Rowley AH, Shulman ST, Spike BT, Mask CA, Baker SC.

J Immunol. 2001 Jan 15;166(2):1334-43.

24.

ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage.

Aladjem MI, Spike BT, Rodewald LW, Hope TJ, Klemm M, Jaenisch R, Wahl GM.

Curr Biol. 1998 Jan 29;8(3):145-55.

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