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Items: 7


╬▒-synuclein expression from a single copy transgene increases sensitivity to stress and accelerates neuronal loss in genetic models of Parkinson's disease.

Cooper JF, Spielbauer KK, Senchuk MM, Nadarajan S, Colaiácovo MP, Van Raamsdonk JM.

Exp Neurol. 2018 Dec;310:58-69. doi: 10.1016/j.expneurol.2018.09.001. Epub 2018 Sep 5.


PD-1 Inhibition Minimally Affects Cisplatin-Induced Toxicities in a Murine Model.

Spielbauer K, Cunningham L, Schmitt N.

Otolaryngol Head Neck Surg. 2018 Aug;159(2):343-346. doi: 10.1177/0194599818767621. Epub 2018 Apr 3.


Activation of the mitochondrial unfolded protein response promotes longevity and dopamine neuron survival in Parkinson's disease models.

Cooper JF, Machiela E, Dues DJ, Spielbauer KK, Senchuk MM, Van Raamsdonk JM.

Sci Rep. 2017 Nov 27;7(1):16441. doi: 10.1038/s41598-017-16637-2.


Cisplatin is retained in the cochlea indefinitely following chemotherapy.

Breglio AM, Rusheen AE, Shide ED, Fernandez KA, Spielbauer KK, McLachlin KM, Hall MD, Amable L, Cunningham LL.

Nat Commun. 2017 Nov 21;8(1):1654. doi: 10.1038/s41467-017-01837-1.


Cisplatin Alters Antitumor Immunity and Synergizes with PD-1/PD-L1 Inhibition in Head and Neck Squamous Cell Carcinoma.

Tran L, Allen CT, Xiao R, Moore E, Davis R, Park SJ, Spielbauer K, Van Waes C, Schmitt NC.

Cancer Immunol Res. 2017 Dec;5(12):1141-1151. doi: 10.1158/2326-6066.CIR-17-0235. Epub 2017 Nov 2.


Delaying aging is neuroprotective in Parkinson's disease: a genetic analysis in C. elegans models.

Cooper JF, Dues DJ, Spielbauer KK, Machiela E, Senchuk MM, Van Raamsdonk JM.

NPJ Parkinsons Dis. 2015 Nov 19;1:15022. doi: 10.1038/npjparkd.2015.22. eCollection 2015.


Mitochondrial and cytoplasmic ROS have opposing effects on lifespan.

Schaar CE, Dues DJ, Spielbauer KK, Machiela E, Cooper JF, Senchuk M, Hekimi S, Van Raamsdonk JM.

PLoS Genet. 2015 Feb 11;11(2):e1004972. doi: 10.1371/journal.pgen.1004972. eCollection 2015 Feb.

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