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Items: 16


Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes.

Pasquier A, Vivot K, Erbs E, Spiegelhalter C, Zhang Z, Aubert V, Liu Z, Senkara M, Maillard E, Pinget M, Kerr-Conte J, Pattou F, Marciniak G, Ganzhorn A, Ronchi P, Schieber NL, Schwab Y, Saftig P, Goginashvili A, Ricci R.

Nat Commun. 2019 Jul 25;10(1):3312. doi: 10.1038/s41467-019-11170-4.


Macrophage functionality and homeostasis in response to oligoethyleneglycol-coated IONPs: Impact of a dendritic architecture.

Casset A, Jouhannaud J, Garofalo A, Spiegelhalter C, Nguyen DV, Felder-Flesch D, Pourroy G, Pons F.

Int J Pharm. 2019 Feb 10;556:287-300. doi: 10.1016/j.ijpharm.2018.12.024. Epub 2018 Dec 14.


ReAsH/tetracystein-based correlative light-electron microscopy for HIV-1 imaging during the early stages of infection.

Lysova I, Spiegelhalter C, Réal E, Zgheib S, Anton H, Mély Y.

Methods Appl Fluoresc. 2018 Jul 9;6(4):045001. doi: 10.1088/2050-6120/aacec1.


Modulation of large dense core vesicle insulin content mediates rhythmic hormone release from pancreatic beta cells over the 24h cycle.

Quinault A, Leloup C, Denwood G, Spiegelhalter C, Rodriguez M, Lefebvre P, Messaddeq N, Zhang Q, Dacquet C, Pénicaud L, Collins SC.

PLoS One. 2018 Mar 15;13(3):e0193882. doi: 10.1371/journal.pone.0193882. eCollection 2018.


RAL-1 controls multivesicular body biogenesis and exosome secretion.

Hyenne V, Apaydin A, Rodriguez D, Spiegelhalter C, Hoff-Yoessle S, Diem M, Tak S, Lefebvre O, Schwab Y, Goetz JG, Labouesse M.

J Cell Biol. 2015 Oct 12;211(1):27-37. doi: 10.1083/jcb.201504136.


Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies.

Ramspacher C, Steed E, Boselli F, Ferreira R, Faggianelli N, Roth S, Spiegelhalter C, Messaddeq N, Trinh L, Liebling M, Chacko N, Tessadori F, Bakkers J, Laporte J, Hnia K, Vermot J.

Cell Rep. 2015 Jun 16;11(10):1564-76. doi: 10.1016/j.celrep.2015.05.010. Epub 2015 Jun 4.


Insulin granules. Insulin secretory granules control autophagy in pancreatic β cells.

Goginashvili A, Zhang Z, Erbs E, Spiegelhalter C, Kessler P, Mihlan M, Pasquier A, Krupina K, Schieber N, Cinque L, Morvan J, Sumara I, Schwab Y, Settembre C, Ricci R.

Science. 2015 Feb 20;347(6224):878-82. doi: 10.1126/science.aaa2628.


Higher chromatin mobility supports totipotency and precedes pluripotency in vivo.

Bošković A, Eid A, Pontabry J, Ishiuchi T, Spiegelhalter C, Raghu Ram EV, Meshorer E, Torres-Padilla ME.

Genes Dev. 2014 May 15;28(10):1042-7. doi: 10.1101/gad.238881.114.


Autistic-like syndrome in mu opioid receptor null mice is relieved by facilitated mGluR4 activity.

Becker JA, Clesse D, Spiegelhalter C, Schwab Y, Le Merrer J, Kieffer BL.

Neuropsychopharmacology. 2014 Aug;39(9):2049-60. doi: 10.1038/npp.2014.59. Epub 2014 Mar 12.


Correlative light and electron microscopy: from live cell dynamic to 3D ultrastructure.

Spiegelhalter C, Laporte JF, Schwab Y.

Methods Mol Biol. 2014;1117:485-501. doi: 10.1007/978-1-62703-776-1_21.


STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the ER.

Alpy F, Rousseau A, Schwab Y, Legueux F, Stoll I, Wendling C, Spiegelhalter C, Kessler P, Mathelin C, Rio MC, Levine TP, Tomasetto C.

J Cell Sci. 2013 Dec 1;126(Pt 23):5500-12. doi: 10.1242/jcs.139295. Epub 2013 Oct 8.


Birbeck granule-like "organized smooth endoplasmic reticulum" resulting from the expression of a cytoplasmic YFP-tagged langerin.

Lenormand C, Spiegelhalter C, Cinquin B, Bardin S, Bausinger H, Angénieux C, Eckly A, Proamer F, Wall D, Lich B, Tourne S, Hanau D, Schwab Y, Salamero J, de la Salle H.

PLoS One. 2013;8(4):e60813. doi: 10.1371/journal.pone.0060813. Epub 2013 Apr 5.


Immunomodulatory properties of multi-walled carbon nanotubes in peripheral blood mononuclear cells from healthy subjects and allergic patients.

Laverny G, Casset A, Purohit A, Schaeffer E, Spiegelhalter C, de Blay F, Pons F.

Toxicol Lett. 2013 Feb 27;217(2):91-101. doi: 10.1016/j.toxlet.2012.12.008. Epub 2012 Dec 20.


Perispeckles are major assembly sites for the exon junction core complex.

Daguenet E, Baguet A, Degot S, Schmidt U, Alpy F, Wendling C, Spiegelhalter C, Kessler P, Rio MC, Le Hir H, Bertrand E, Tomasetto C.

Mol Biol Cell. 2012 May;23(9):1765-82. doi: 10.1091/mbc.E12-01-0040. Epub 2012 Mar 14.


Lung deposition and toxicological responses evoked by multi-walled carbon nanotubes dispersed in a synthetic lung surfactant in the mouse.

Ronzani C, Spiegelhalter C, Vonesch JL, Lebeau L, Pons F.

Arch Toxicol. 2012 Jan;86(1):137-49. doi: 10.1007/s00204-011-0741-y. Epub 2011 Jul 30.


From dynamic live cell imaging to 3D ultrastructure: novel integrated methods for high pressure freezing and correlative light-electron microscopy.

Spiegelhalter C, Tosch V, Hentsch D, Koch M, Kessler P, Schwab Y, Laporte J.

PLoS One. 2010 Feb 3;5(2):e9014. doi: 10.1371/journal.pone.0009014.

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