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Sleep-Related Disorders in Neurology and Psychiatry.

Rémi J, Pollmächer T, Spiegelhalder K, Trenkwalder C, Young P.

Dtsch Arztebl Int. 2019 Oct 11;116(41):681-688. doi: 10.3238/arztebl.2019.0681.


Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes.

Wang H, Lane JM, Jones SE, Dashti HS, Ollila HM, Wood AR, van Hees VT, Brumpton B, Winsvold BS, Kantojärvi K, Palviainen T, Cade BE, Sofer T, Song Y, Patel K, Anderson SG, Bechtold DA, Bowden J, Emsley R, Kyle SD, Little MA, Loudon AS, Scheer FAJL, Purcell SM, Richmond RC, Spiegelhalder K, Tyrrell J, Zhu X, Hublin C, Kaprio JA, Kristiansson K, Sulkava S, Paunio T, Hveem K, Nielsen JB, Willer CJ, Zwart JA, Strand LB, Frayling TM, Ray D, Lawlor DA, Rutter MK, Weedon MN, Redline S, Saxena R.

Nat Commun. 2019 Aug 13;10(1):3503. doi: 10.1038/s41467-019-11456-7.


Neuroimaging insights into the link between depression and Insomnia: A systematic review.

Bagherzadeh-Azbari S, Khazaie H, Zarei M, Spiegelhalder K, Walter M, Leerssen J, Van Someren EJW, Sepehry AA, Tahmasian M.

J Affect Disord. 2019 Nov 1;258:133-143. doi: 10.1016/j.jad.2019.07.089. Epub 2019 Jul 31. Review.


Changes in sleep architecture in German Armed Forces personnel with posttraumatic stress disorder compared with depressed and healthy control subjects.

Haberland L, Höllmer H, Schulz H, Spiegelhalder K, Gorzka R.

PLoS One. 2019 Apr 17;14(4):e0215355. doi: 10.1371/journal.pone.0215355. eCollection 2019.


Editorial: Neuroimaging Findings in Sleep Disorders and Circadian Disruption.

Dai XJ, Rao H, Spiegelhalder K.

Front Neurol. 2019 Mar 21;10:249. doi: 10.3389/fneur.2019.00249. eCollection 2019. No abstract available.


Can spectral power predict subjective sleep quality in healthy individuals?

Gabryelska A, Feige B, Riemann D, Spiegelhalder K, Johann A, Białasiewicz P, Hertenstein E.

J Sleep Res. 2019 Dec;28(6):e12848. doi: 10.1111/jsr.12848. Epub 2019 Apr 1.


Pre-Sleep Arousal Scale (PSAS) and the Time Monitoring Behavior-10 scale (TMB-10) in good sleepers and patients with insomnia.

Vochem J, Strobel C, Maier L, Spiegelhalder K, Hertenstein E, Riemann D, Feige B.

Sleep Med. 2019 Apr;56:98-103. doi: 10.1016/j.sleep.2019.01.022. Epub 2019 Jan 30.


Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates.

Dashti HS, Jones SE, Wood AR, Lane JM, van Hees VT, Wang H, Rhodes JA, Song Y, Patel K, Anderson SG, Beaumont RN, Bechtold DA, Bowden J, Cade BE, Garaulet M, Kyle SD, Little MA, Loudon AS, Luik AI, Scheer FAJL, Spiegelhalder K, Tyrrell J, Gottlieb DJ, Tiemeier H, Ray DW, Purcell SM, Frayling TM, Redline S, Lawlor DA, Rutter MK, Weedon MN, Saxena R.

Nat Commun. 2019 Mar 7;10(1):1100. doi: 10.1038/s41467-019-08917-4.


Biological and clinical insights from genetics of insomnia symptoms.

Lane JM, Jones SE, Dashti HS, Wood AR, Aragam KG, van Hees VT, Strand LB, Winsvold BS, Wang H, Bowden J, Song Y, Patel K, Anderson SG, Beaumont RN, Bechtold DA, Cade BE, Haas M, Kathiresan S, Little MA, Luik AI, Loudon AS, Purcell S, Richmond RC, Scheer FAJL, Schormair B, Tyrrell J, Winkelman JW, Winkelmann J; HUNT All In Sleep, Hveem K, Zhao C, Nielsen JB, Willer CJ, Redline S, Spiegelhalder K, Kyle SD, Ray DW, Zwart JA, Brumpton B, Frayling TM, Lawlor DA, Rutter MK, Weedon MN, Saxena R.

Nat Genet. 2019 Mar;51(3):387-393. doi: 10.1038/s41588-019-0361-7. Epub 2019 Feb 25.


Differential effects of bifrontal tDCS on arousal and sleep duration in insomnia patients and healthy controls.

Frase L, Selhausen P, Krone L, Tsodor S, Jahn F, Feige B, Maier JG, Mainberger F, Piosczyk H, Kuhn M, Klöppel S, Sterr A, Baglioni C, Spiegelhalder K, Riemann D, Nitsche MA, Nissen C.

Brain Stimul. 2019 May - Jun;12(3):674-683. doi: 10.1016/j.brs.2019.01.001. Epub 2019 Jan 4.


Sleep orchestrates indices of local plasticity and global network stability in the human cortex.

Maier JG, Kuhn M, Mainberger F, Nachtsheim K, Guo S, Bucsenez U, Feige B, Mikutta C, Spiegelhalder K, Klöppel S, Normann C, Riemann D, Nissen C.

Sleep. 2019 Apr 1;42(4). pii: zsy263. doi: 10.1093/sleep/zsy263.


Cognitive behavioral treatment for insomnia is equally effective in insomnia patients with objective short and normal sleep duration.

Crönlein T, Wetter TC, Rupprecht R, Spiegelhalder K.

Sleep Med. 2018 Nov 26. pii: S1389-9457(18)30535-5. doi: 10.1016/j.sleep.2018.10.038. [Epub ahead of print]


Insomnia as a predictor of mental disorders: A systematic review and meta-analysis.

Hertenstein E, Feige B, Gmeiner T, Kienzler C, Spiegelhalder K, Johann A, Jansson-Fröjmark M, Palagini L, Rücker G, Riemann D, Baglioni C.

Sleep Med Rev. 2019 Feb;43:96-105. doi: 10.1016/j.smrv.2018.10.006. Epub 2018 Nov 16.


Reply to Hua Liu, HaiCun Shi and PingLei Pan: Coordinate based meta-analyses in a medium sized literature: Considerations, limitations and road ahead.

Tahmasian M, Zarei M, Noori K, Khazaie H, Samea F, Spiegelhalder K, Eickhoff SB, Van Someren E, Eickhoff CR.

Sleep Med Rev. 2018 Dec;42:236-238. doi: 10.1016/j.smrv.2018.08.004. Epub 2018 Aug 26. No abstract available.


Making sleep easier: pharmacological interventions for insomnia.

Frase L, Nissen C, Riemann D, Spiegelhalder K.

Expert Opin Pharmacother. 2018 Sep;19(13):1465-1473. doi: 10.1080/14656566.2018.1511705. Epub 2018 Sep 3. Review.


A lack of consistent brain alterations in insomnia disorder: An activation likelihood estimation meta-analysis.

Tahmasian M, Noori K, Samea F, Zarei M, Spiegelhalder K, Eickhoff SB, Van Someren E, Khazaie H, Eickhoff CR.

Sleep Med Rev. 2018 Dec;42:111-118. doi: 10.1016/j.smrv.2018.07.004. Epub 2018 Jul 10. Review.


Declarative virtual water maze learning and emotional fear conditioning in primary insomnia.

Kuhn M, Hertenstein E, Feige B, Landmann N, Spiegelhalder K, Baglioni C, Hemmerling J, Durand D, Frase L, Klöppel S, Riemann D, Nissen C.

J Sleep Res. 2018 Dec;27(6):e12693. doi: 10.1111/jsr.12693. Epub 2018 May 2.


Reference Data for Polysomnography-Measured and Subjective Sleep in Healthy Adults.

Hertenstein E, Gabryelska A, Spiegelhalder K, Nissen C, Johann AF, Umarova R, Riemann D, Baglioni C, Feige B.

J Clin Sleep Med. 2018 Apr 15;14(4):523-532. doi: 10.5664/jcsm.7036.


Does Perfectionism Increase the Risk for Dropout From Cognitive Behavioral Therapy for Insomnia?

Johann AF, Riemann D, Spiegelhalder K.

J Clin Sleep Med. 2018 Mar 15;14(3):487-488. doi: 10.5664/jcsm.7012. No abstract available.


Sleep and cognitive performance: cross-sectional associations in the UK Biobank.

Kyle SD, Sexton CE, Feige B, Luik AI, Lane J, Saxena R, Anderson SG, Bechtold DA, Dixon W, Little MA, Ray D, Riemann D, Espie CA, Rutter MK, Spiegelhalder K.

Sleep Med. 2017 Oct;38:85-91. doi: 10.1016/j.sleep.2017.07.001. Epub 2017 Jul 14.


Perfectionism and Polysomnography-Determined Markers of Poor Sleep.

Johann AF, Hertenstein E, Kyle SD, Baglioni C, Feige B, Nissen C, Riemann D, Spiegelhalder K.

J Clin Sleep Med. 2017 Nov 15;13(11):1319-1326. doi: 10.5664/jcsm.6806.


Sleep Stage Transition Dynamics Reveal Specific Stage 2 Vulnerability in Insomnia.

Wei Y, Colombo MA, Ramautar JR, Blanken TF, van der Werf YD, Spiegelhalder K, Feige B, Riemann D, Van Someren EJW.

Sleep. 2017 Sep 1;40(9). doi: 10.1093/sleep/zsx117.


European guideline for the diagnosis and treatment of insomnia.

Riemann D, Baglioni C, Bassetti C, Bjorvatn B, Dolenc Groselj L, Ellis JG, Espie CA, Garcia-Borreguero D, Gjerstad M, Gonçalves M, Hertenstein E, Jansson-Fröjmark M, Jennum PJ, Leger D, Nissen C, Parrino L, Paunio T, Pevernagie D, Verbraecken J, Weeß HG, Wichniak A, Zavalko I, Arnardottir ES, Deleanu OC, Strazisar B, Zoetmulder M, Spiegelhalder K.

J Sleep Res. 2017 Dec;26(6):675-700. doi: 10.1111/jsr.12594. Epub 2017 Sep 5.


Brief periods of NREM sleep do not promote early offline gains but subsequent on-task performance in motor skill learning.

Maier JG, Piosczyk H, Holz J, Landmann N, Deschler C, Frase L, Kuhn M, Klöppel S, Spiegelhalder K, Sterr A, Riemann D, Feige B, Voderholzer U, Nissen C.

Neurobiol Learn Mem. 2017 Nov;145:18-27. doi: 10.1016/j.nlm.2017.08.006. Epub 2017 Aug 19.


Insomnia with objective short sleep duration is associated with longer duration of insomnia in the Freiburg Insomnia Cohort compared to insomnia with normal sleep duration, but not with hypertension.

Johann AF, Hertenstein E, Kyle SD, Baglioni C, Feige B, Nissen C, McGinness AJ, Riemann D, Spiegelhalder K.

PLoS One. 2017 Jul 26;12(7):e0180339. doi: 10.1371/journal.pone.0180339. eCollection 2017.


Associations between self-reported sleep quality and white matter in community-dwelling older adults: A prospective cohort study.

Sexton CE, Zsoldos E, Filippini N, Griffanti L, Winkler A, Mahmood A, Allan CL, Topiwala A, Kyle SD, Spiegelhalder K, Singh-Manoux A, Kivimaki M, Mackay CE, Johansen-Berg H, Ebmeier KP.

Hum Brain Mapp. 2017 Nov;38(11):5465-5473. doi: 10.1002/hbm.23739. Epub 2017 Jul 26.


Clinical Sleep-Wake Disorders II: Focus on Insomnia and Circadian Rhythm Sleep Disorders.

Spiegelhalder K, Nissen C, Riemann D.

Handb Exp Pharmacol. 2019;253:261-276. doi: 10.1007/164_2017_40.


Effects of digital Cognitive Behavioural Therapy for Insomnia on cognitive function: study protocol for a randomised controlled trial.

Kyle SD, Hurry MED, Emsley R, Luik AI, Omlin X, Spiegelhalder K, Espie CA, Sexton CE.

Trials. 2017 Jun 17;18(1):281. doi: 10.1186/s13063-017-2012-6.


The effectiveness of behavioural and cognitive behavioural therapies for insomnia on depressive and fatigue symptoms: A systematic review and network meta-analysis.

Ballesio A, Aquino MRJV, Feige B, Johann AF, Kyle SD, Spiegelhalder K, Lombardo C, Rücker G, Riemann D, Baglioni C.

Sleep Med Rev. 2018 Feb;37:114-129. doi: 10.1016/j.smrv.2017.01.006. Epub 2017 Feb 7. Review.


Functional reorganization in obstructive sleep apnoea and insomnia: A systematic review of the resting-state fMRI.

Khazaie H, Veronese M, Noori K, Emamian F, Zarei M, Ashkan K, Leschziner GD, Eickhoff CR, Eickhoff SB, Morrell MJ, Osorio RS, Spiegelhalder K, Tahmasian M, Rosenzweig I.

Neurosci Biobehav Rev. 2017 Jun;77:219-231. doi: 10.1016/j.neubiorev.2017.03.013. Epub 2017 Mar 23. Review.


Brain Reactivity and Selective Attention to Sleep-Related Words in Patients With Chronic Insomnia.

Spiegelhalder K, Baglioni C, Regen W, Kyle SD, Nissen C, Hennig J, Doerr JP, Feige B, Riemann D.

Behav Sleep Med. 2018 Nov-Dec;16(6):587-600. doi: 10.1080/15402002.2016.1253014. Epub 2016 Dec 14.


Distinctive time-lagged resting-state networks revealed by simultaneous EEG-fMRI.

Feige B, Spiegelhalder K, Kiemen A, Bosch OG, Tebartz van Elst L, Hennig J, Seifritz E, Riemann D.

Neuroimage. 2017 Jan 15;145(Pt A):1-10. doi: 10.1016/j.neuroimage.2016.09.027. Epub 2016 Sep 13.


Sleep recalibrates homeostatic and associative synaptic plasticity in the human cortex.

Kuhn M, Wolf E, Maier JG, Mainberger F, Feige B, Schmid H, Bürklin J, Maywald S, Mall V, Jung NH, Reis J, Spiegelhalder K, Klöppel S, Sterr A, Eckert A, Riemann D, Normann C, Nissen C.

Nat Commun. 2016 Aug 23;7:12455. doi: 10.1038/ncomms12455.


Sleep and mental disorders: A meta-analysis of polysomnographic research.

Baglioni C, Nanovska S, Regen W, Spiegelhalder K, Feige B, Nissen C, Reynolds CF, Riemann D.

Psychol Bull. 2016 Sep;142(9):969-990. Epub 2016 Jul 14. Review.


Magnetic Resonance Spectroscopy in Patients with Insomnia: A Repeated Measurement Study.

Spiegelhalder K, Regen W, Nissen C, Feige B, Baglioni C, Riemann D, Hennig J, Lange T.

PLoS One. 2016 Jun 10;11(6):e0156771. doi: 10.1371/journal.pone.0156771. eCollection 2016.


Correction: Polysomnographic Characteristics of Sleep in Stroke: A Systematic Review and Meta-Analysis.

Baglioni C, Nissen C, Schweinoch A, Riemann D, Spiegelhalder K, Berger M, Weiller C, Sterr A.

PLoS One. 2016 May 11;11(5):e0155652. doi: 10.1371/journal.pone.0155652. eCollection 2016.


Modulation of Total Sleep Time by Transcranial Direct Current Stimulation (tDCS).

Frase L, Piosczyk H, Zittel S, Jahn F, Selhausen P, Krone L, Feige B, Mainberger F, Maier JG, Kuhn M, Klöppel S, Normann C, Sterr A, Spiegelhalder K, Riemann D, Nitsche MA, Nissen C.

Neuropsychopharmacology. 2016 Sep;41(10):2577-86. doi: 10.1038/npp.2016.65. Epub 2016 May 4.


Polysomnographic Characteristics of Sleep in Stroke: A Systematic Review and Meta-Analysis.

Baglioni C, Nissen C, Schweinoch A, Riemann D, Spiegelhalder K, Berger M, Weiller C, Sterr A.

PLoS One. 2016 Mar 7;11(3):e0148496. doi: 10.1371/journal.pone.0148496. eCollection 2016. Review. Erratum in: PLoS One. 2016;11(5):e0155652.


Top-down control of arousal and sleep: Fundamentals and clinical implications.

Krone L, Frase L, Piosczyk H, Selhausen P, Zittel S, Jahn F, Kuhn M, Feige B, Mainberger F, Klöppel S, Riemann D, Spiegelhalder K, Baglioni C, Sterr A, Nissen C.

Sleep Med Rev. 2017 Feb;31:17-24. doi: 10.1016/j.smrv.2015.12.005. Epub 2016 Jan 14. Review.


Slow dissolving of emotional distress contributes to hyperarousal.

Wassing R, Benjamins JS, Dekker K, Moens S, Spiegelhalder K, Feige B, Riemann D, van der Sluis S, Van Der Werf YD, Talamini LM, Walker MP, Schalkwijk F, Van Someren EJ.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):2538-43. doi: 10.1073/pnas.1522520113. Epub 2016 Feb 8.


Objective sleep disturbances are associated with greater waking resting-state connectivity between the retrosplenial cortex/ hippocampus and various nodes of the default mode network.

Regen W, Kyle SD, Nissen C, Feige B, Baglioni C, Hennig J, Riemann D, Spiegelhalder K.

J Psychiatry Neurosci. 2016 Aug;41(5):295-303. doi: 10.1503/jpn.140290.


Your Place or Mine? Does the Sleep Location Matter in Young Couples?

Spiegelhalder K, Regen W, Siemon F, Kyle SD, Baglioni C, Feige B, Nissen C, Riemann D.

Behav Sleep Med. 2017 Mar-Apr;15(2):87-96. doi: 10.1080/15402002.2015.1083024. Epub 2015 Dec 17. Erratum in: Behav Sleep Med. 2017 Mar-Apr;15(2):172-173.


Sleep Strengthens but does Not Reorganize Memory Traces in a Verbal Creativity Task.

Landmann N, Kuhn M, Maier JG, Feige B, Spiegelhalder K, Riemann D, Nissen C.

Sleep. 2016 Mar 1;39(3):705-13. doi: 10.5665/sleep.5556.


Sleep-related attentional bias in insomnia: A state-of-the-science review.

Harris K, Spiegelhalder K, Espie CA, MacMahon KM, Woods HC, Kyle SD.

Clin Psychol Rev. 2015 Dec;42:16-27. doi: 10.1016/j.cpr.2015.08.001. Epub 2015 Aug 6. Review.


Losing sleep.

Spiegelhalder K, Riemann D.

Lancet Neurol. 2015 Jun;14(6):571. doi: 10.1016/S1474-4422(15)00065-4. No abstract available.


The neurobiology, investigation, and treatment of chronic insomnia.

Riemann D, Nissen C, Palagini L, Otte A, Perlis ML, Spiegelhalder K.

Lancet Neurol. 2015 May;14(5):547-58. doi: 10.1016/S1474-4422(15)00021-6. Epub 2015 Apr 12. Review.


Insomnia research--Time for "fine-tuning".

Riemann D, Spiegelhalder K.

Sleep Med Rev. 2015 Oct;23:89-90. doi: 10.1016/j.smrv.2015.02.004. Epub 2015 Feb 25. No abstract available.


The exploratory power of sleep effort, dysfunctional beliefs and arousal for insomnia severity and polysomnography-determined sleep.

Hertenstein E, Nissen C, Riemann D, Feige B, Baglioni C, Spiegelhalder K.

J Sleep Res. 2015 Aug;24(4):399-406. doi: 10.1111/jsr.12293. Epub 2015 Mar 14.


Neuroimaging insights into insomnia.

Spiegelhalder K, Regen W, Baglioni C, Nissen C, Riemann D, Kyle SD.

Curr Neurol Neurosci Rep. 2015 Mar;15(3):9. doi: 10.1007/s11910-015-0527-3. Review.


Patients with primary insomnia in the sleep laboratory: do they present with typical nights of sleep?

Hirscher V, Unbehaun T, Feige B, Nissen C, Riemann D, Spiegelhalder K.

J Sleep Res. 2015 Aug;24(4):383-9. doi: 10.1111/jsr.12280. Epub 2015 Feb 9.

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