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Items: 16


Evofosfamide sensitizes esophageal carcinomas to radiation without increasing normal tissue toxicity.

Spiegelberg L, van Hoof SJ, Biemans R, Lieuwes NG, Marcus D, Niemans R, Theys J, Yaromina A, Lambin P, Verhaegen F, Dubois LJ.

Radiother Oncol. 2019 Aug 17. pii: S0167-8140(19)32975-5. doi: 10.1016/j.radonc.2019.06.034. [Epub ahead of print]


Hypoxia-activated prodrugs and (lack of) clinical progress: The need for hypoxia-based biomarker patient selection in phase III clinical trials.

Spiegelberg L, Houben R, Niemans R, de Ruysscher D, Yaromina A, Theys J, Guise CP, Smaill JB, Patterson AV, Lambin P, Dubois LJ.

Clin Transl Radiat Oncol. 2019 Jan 18;15:62-69. doi: 10.1016/j.ctro.2019.01.005. eCollection 2019 Feb.


An orthotopic non-small cell lung cancer model for image-guided small animal radiotherapy platforms.

Sosa Iglesias V, van Hoof SJ, Vaniqui A, Schyns LE, Lieuwes N, Yaromina A, Spiegelberg L, Groot AJ, Verhaegen F, Theys J, Dubois L, Vooijs M.

Br J Radiol. 2019 Mar;92(1095):20180476. doi: 10.1259/bjr.20180476. Epub 2018 Nov 30.


Hypoxia and hypoxia response-associated molecular markers in esophageal cancer: A systematic review.

Peerlings J, Van De Voorde L, Mitea C, Larue R, Yaromina A, Sandeleanu S, Spiegelberg L, Dubois L, Lambin P, Mottaghy FM.

Methods. 2017 Nov 1;130:51-62. doi: 10.1016/j.ymeth.2017.07.002. Epub 2017 Jul 10. Review.


New ways to image and target tumour hypoxia and its molecular responses.

Dubois LJ, Niemans R, van Kuijk SJ, Panth KM, Parvathaneni NK, Peeters SG, Zegers CM, Rekers NH, van Gisbergen MW, Biemans R, Lieuwes NG, Spiegelberg L, Yaromina A, Winum JY, Vooijs M, Lambin P.

Radiother Oncol. 2015 Sep;116(3):352-7. doi: 10.1016/j.radonc.2015.08.022. Epub 2015 Aug 28. Review.


Optical Imaging of Tumor Response to Hyperbaric Oxygen Treatment and Irradiation in an Orthotopic Mouse Model of Head and Neck Squamous Cell Carcinoma.

Braks JA, Spiegelberg L, Koljenovic S, Ridwan Y, Keereweer S, Kanaar R, Wolvius EB, Essers J.

Mol Imaging Biol. 2015 Oct;17(5):633-42. doi: 10.1007/s11307-015-0834-8.


Hyperbaric oxygen therapy as a prevention modality for radiation damage in the mandibles of mice.

Spiegelberg L, Braks JA, Groeneveldt LC, Djasim UM, van der Wal KG, Wolvius EB.

J Craniomaxillofac Surg. 2015 Mar;43(2):214-9. doi: 10.1016/j.jcms.2014.11.008. Epub 2014 Nov 18.


Gene expression analysis reveals inhibition of radiation-induced TGFβ-signaling by hyperbaric oxygen therapy in mouse salivary glands.

Spiegelberg L, Swagemakers SM, Van Ijcken WF, Oole E, Wolvius EB, Essers J, Braks JA.

Mol Med. 2014 Jul 10;20:257-69. doi: 10.2119/molmed.2014.00003.


Hyperbaric oxygen treatment of tissue-engineered mucosa enhances secretion of angiogenic factors in vitro.

Tra WM, Spiegelberg L, Tuk B, Hovius SE, Perez-Amodio S.

Tissue Eng Part A. 2014 May;20(9-10):1523-30. doi: 10.1089/ten.TEA.2012.0629. Epub 2014 Apr 7.


Effects of hyperbaric oxygen therapy on the viability of irradiated soft head and neck tissues in mice.

Spiegelberg L, Braks JA, Djasim UM, Farrell E, van der Wal KG, Wolvius EB.

Oral Dis. 2014 Apr;20(3):e111-9. doi: 10.1111/odi.12162. Epub 2013 Jul 19.


Human cell tropism and innate immune system interactions of human respiratory coronavirus EMC compared to those of severe acute respiratory syndrome coronavirus.

Zielecki F, Weber M, Eickmann M, Spiegelberg L, Zaki AM, Matrosovich M, Becker S, Weber F.

J Virol. 2013 May;87(9):5300-4. doi: 10.1128/JVI.03496-12. Epub 2013 Feb 28.


The effects of heparan sulphate mimetic RGTA-OTR4120 on irradiated murine salivary glands.

Spiegelberg L, Djasim UM, van Neck JW, Wolvius EB, van der Wal KG.

J Oral Pathol Med. 2012 Jul;41(6):477-83. doi: 10.1111/j.1600-0714.2011.01124.x. Epub 2012 Jan 10.


A hyperbaric oxygen chamber for animal experimental purposes.

Djasim UM, Spiegelberg L, Wolvius EB, van der Wal KG.

Int J Oral Maxillofac Surg. 2012 Feb;41(2):271-4. doi: 10.1016/j.ijom.2011.10.007. Epub 2011 Dec 29.


Genus-specific recruitment of filovirus ribonucleoprotein complexes into budding particles.

Spiegelberg L, Wahl-Jensen V, Kolesnikova L, Feldmann H, Becker S, Hoenen T.

J Gen Virol. 2011 Dec;92(Pt 12):2900-2905. doi: 10.1099/vir.0.036863-0. Epub 2011 Sep 7.


Hyperbaric oxygen therapy in the management of radiation-induced injury in the head and neck region: a review of the literature.

Spiegelberg L, Djasim UM, van Neck HW, Wolvius EB, van der Wal KG.

J Oral Maxillofac Surg. 2010 Aug;68(8):1732-9. doi: 10.1016/j.joms.2010.02.040. Epub 2010 May 20. Review.


Ultrastructural and immunocytochemical characterization of the rat non-preganglionic Edinger-Westphal nucleus.

Van Wijk DC, Xu L, Spiegelberg L, Struik RF, Meijer KH, Gaszner B, Kozicz T, Roubos EW.

Gen Comp Endocrinol. 2009 Oct;164(1):32-9. doi: 10.1016/j.ygcen.2009.04.002. Epub 2009 Apr 10.


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