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Items: 1 to 50 of 135

1.

Socioeconomic Status Influences Functional Severity of Untreated Cerebral Palsy in Nepal: A Prospective Analysis and Systematic Review.

LeBrun DG, Banskota B, Banskota AK, Rajbhandari T, Baldwin KD, Spiegel DA.

Clin Orthop Relat Res. 2018 Aug 30. doi: 10.1097/CORR.0000000000000476. [Epub ahead of print]

PMID:
30179955
2.

Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks.

Galligan JJ, Wepy JA, Streeter MD, Kingsley PJ, Mitchener MM, Wauchope OR, Beavers WN, Rose KL, Wang T, Spiegel DA, Marnett LJ.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9228-9233. doi: 10.1073/pnas.1802901115. Epub 2018 Aug 27.

3.

Factors that Predict Overall Health and Quality of Life in Non-Ambulatory Individuals with Cerebral Palsy.

Kolman SE, Glanzman AM, Prosser L, Spiegel DA, Baldwin KD.

Iowa Orthop J. 2018;38:147-152.

4.

Releasing the tether: Weight normalization following corrective spinal fusion in cerebral palsy.

DeFrancesco CJ, Miller DJ, Cahill PJ, Spiegel DA, Flynn JM, Baldwin KD.

J Orthop Surg (Hong Kong). 2018 May-Aug;26(2):2309499018782556. doi: 10.1177/2309499018782556.

PMID:
29938586
5.

Access to Orthopaedic Surgical Care in Northern Tanzania: A Modelling Study.

Premkumar A, Ying X, Mack Hardaker W, Massawe HH, Mshahaba DJ, Mandari F, Pallangyo A, Temu R, Masenga G, Spiegel DA, Sheth NP.

World J Surg. 2018 Oct;42(10):3081-3088. doi: 10.1007/s00268-018-4630-x.

PMID:
29696326
6.

Total Synthesis of (±)-Phomoidride D.

Leung JC, Bedermann AA, Njardarson JT, Spiegel DA, Murphy GK, Hama N, Twenter BM, Dong P, Shirahata T, McDonald IM, Inoue M, Taniguchi N, McMahon TC, Schneider CM, Tao N, Stoltz BM, Wood JL.

Angew Chem Int Ed Engl. 2018 Feb 12;57(7):1991-1994. doi: 10.1002/anie.201712369. Epub 2018 Jan 17.

PMID:
29286556
7.

Predictors of healthcare seeking delays among children with chronic musculoskeletal disorders in Nepal.

LeBrun DG, Talwar D, Pham TA, Banskota B, Spiegel DA.

J Epidemiol Glob Health. 2017 Dec;7(4):299-304. doi: 10.1016/j.jegh.2017.10.002. Epub 2017 Oct 12.

8.

Is Systemic Inflammatory Response Syndrome Relevant to Pulmonary Complications and Mortality in Multiply Injured Children?

Al-Mahdi W, Ibrahim MM, Spiegel DA, Arkader A, Nance M, Baldwin K.

J Pediatr Orthop. 2017 Oct 9. doi: 10.1097/BPO.0000000000001085. [Epub ahead of print]

PMID:
29016432
9.

Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death.

Nokin MJ, Durieux F, Bellier J, Peulen O, Uchida K, Spiegel DA, Cochrane JR, Hutton CA, Castronovo V, Bellahcène A.

Sci Rep. 2017 Sep 15;7(1):11722. doi: 10.1038/s41598-017-12119-7.

10.

Post-operative fever in orthopaedic surgery: How effective is the 'fever workup?'

Ashley B, Spiegel DA, Cahill P, Talwar D, Baldwin KD.

J Orthop Surg (Hong Kong). 2017 Sep-Dec;25(3):2309499017727953. doi: 10.1177/2309499017727953.

PMID:
28851265
11.

Neutralization of Pathogenic Fungi with Small-Molecule Immunotherapeutics.

Chirkin E, Muthusamy V, Mann P, Roemer T, Nantermet PG, Spiegel DA.

Angew Chem Int Ed Engl. 2017 Oct 9;56(42):13036-13040. doi: 10.1002/anie.201707536. Epub 2017 Sep 11.

PMID:
28793176
12.

Infection Control in Pediatric Spinal Deformity Surgery: A Systematic and Critical Analysis Review.

Mistovich RJ, Jacobs LJ, Campbell RM, Spiegel DA, Flynn JM, Baldwin KD.

JBJS Rev. 2017 May;5(5):e3. doi: 10.2106/JBJS.RVW.16.00071. No abstract available.

PMID:
28514262
13.

The Clinical Utility of Flexion-Extension Cervical Spine MRI in 22q11.2 Deletion Syndrome.

Kolman SE, Ohara SY, Bhatia A, Feygin T, Colo D, Baldwin KD, Mcdonald-Mcginn D, Spiegel DA.

J Pediatr Orthop. 2017 Apr 24. doi: 10.1097/BPO.0000000000000994. [Epub ahead of print]

PMID:
28441280
14.

Retrospective review of Surgical Availability and Readiness in 8 African countries.

Spiegel DA, Droti B, Relan P, Hobson S, Cherian MN, O'Neill K.

BMJ Open. 2017 Mar 6;7(3):e014496. doi: 10.1136/bmjopen-2016-014496.

15.

Encoded Silicon-Chip-Based Platform for Combinatorial Synthesis and Screening.

Vastl J, Wang T, Trinh TB, Spiegel DA.

ACS Comb Sci. 2017 Apr 10;19(4):255-261. doi: 10.1021/acscombsci.6b00181. Epub 2017 Mar 6.

PMID:
28263558
16.

Predicting Periarticular Infection in Children With Septic Arthritis of the Hip: Regionally Derived Criteria May Not Apply to All Populations.

Refakis CA, Arkader A, Baldwin KD, Spiegel DA, Sankar WN.

J Pediatr Orthop. 2017 Jan 5. doi: 10.1097/BPO.0000000000000934. [Epub ahead of print]

PMID:
28060181
17.

Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.

Nokin MJ, Durieux F, Peixoto P, Chiavarina B, Peulen O, Blomme A, Turtoi A, Costanza B, Smargiasso N, Baiwir D, Scheijen JL, Schalkwijk CG, Leenders J, De Tullio P, Bianchi E, Thiry M, Uchida K, Spiegel DA, Cochrane JR, Hutton CA, De Pauw E, Delvenne P, Belpomme D, Castronovo V, Bellahcène A.

Elife. 2016 Oct 19;5. pii: e19375. doi: 10.7554/eLife.19375.

18.

The Cavovarus Foot in Hereditary Motor and Sensory Neuropathies.

Georgiadis AG, Spiegel DA, Baldwin KD.

JBJS Rev. 2015 Dec 22;3(12). pii: 01874474-201512000-00003. doi: 10.2106/JBJS.RVW.O.00024. No abstract available.

PMID:
27490994
19.

Treatment of the Dislocated Hip in Infants With Spasticity.

Refakis CA, Baldwin KD, Spiegel DA, Sankar WN.

J Pediatr Orthop. 2018 Aug;38(7):345-349. doi: 10.1097/BPO.0000000000000829.

PMID:
27379781
20.

The spatial distribution of injuries in need of surgical intervention in Nepal.

Gupta S, Groen TA, Stewart BT, Shrestha S, Spiegel DA, Nwomeh BC, Groen RS, Kushner AL.

Geospat Health. 2016 May 31;11(2):359. doi: 10.4081/gh.2016.359.

21.

Peptidines: glycine-amidine-based oligomers for solution- and solid-phase synthesis.

Vastl J, Kartika R, Park K, Cho AE, Spiegel DA.

Chem Sci. 2016 May 1;7(5):3317-3324. doi: 10.1039/c5sc03882k. Epub 2016 Feb 16.

22.

The Ponseti Method for Clubfoot Treatment in Low and Middle-Income Countries: A Systematic Review of Barriers and Solutions to Service Delivery.

Johnson RR, Friedman JM, Becker AM, Spiegel DA.

J Pediatr Orthop. 2017 Mar;37(2):e134-e139. doi: 10.1097/BPO.0000000000000723. Review.

PMID:
26919713
23.

Re-engineering the Immune Response to Metastatic Cancer: Antibody-Recruiting Small Molecules Targeting the Urokinase Receptor.

Rullo AF, Fitzgerald KJ, Muthusamy V, Liu M, Yuan C, Huang M, Kim M, Cho AE, Spiegel DA.

Angew Chem Int Ed Engl. 2016 Mar 7;55(11):3642-6. doi: 10.1002/anie.201510866. Epub 2016 Feb 16.

24.

A Nanobody Activation Immunotherapeutic that Selectively Destroys HER2-Positive Breast Cancer Cells.

Gray MA, Tao RN, DePorter SM, Spiegel DA, McNaughton BR.

Chembiochem. 2016 Jan;17(2):155-8. doi: 10.1002/cbic.201500591. Epub 2015 Dec 10.

25.

Wall teichoic acids prevent antibody binding to epitopes within the cell wall of Staphylococcus aureus.

Gautam S, Kim T, Lester E, Deep D, Spiegel DA.

ACS Chem Biol. 2016 Jan 15;11(1):25-30. doi: 10.1021/acschembio.5b00439. Epub 2015 Nov 5.

26.

Concise total synthesis of glucosepane.

Draghici C, Wang T, Spiegel DA.

Science. 2015 Oct 16;350(6258):294-8. doi: 10.1126/science.aac9655.

27.

A Snapshot of 1001 Children Presenting with Cerebral Palsy to a Children's Disability Hospital.

Banskota B, Shrestha S, Rajbhandari T, Banskota AK, Spiegel DA.

J Nepal Health Res Counc. 2015 Jan-Apr;13(29):31-7.

PMID:
26411710
28.

Neuromuscular scoliosis and pelvic fixation in 2015: Where do we stand?

Anari JB, Spiegel DA, Baldwin KD.

World J Orthop. 2015 Sep 18;6(8):564-6. doi: 10.5312/wjo.v6.i8.564. eCollection 2015 Sep 18.

29.

An Activity-Based Probe for Studying Crosslinking in Live Bacteria.

Gautam S, Kim T, Shoda T, Sen S, Deep D, Luthra R, Ferreira MT, Pinho MG, Spiegel DA.

Angew Chem Int Ed Engl. 2015 Sep 1;54(36):10492-6. doi: 10.1002/anie.201503869. Epub 2015 Jul 17.

PMID:
26204841
30.

Generation of political priority for global surgery: a qualitative policy analysis.

Shawar YR, Shiffman J, Spiegel DA.

Lancet Glob Health. 2015 Aug;3(8):e487-e495. doi: 10.1016/S2214-109X(15)00098-4.

31.

Methylglyoxal, the foe and friend of glyoxalase and Trx/TrxR systems in HT22 nerve cells.

Dafre AL, Goldberg J, Wang T, Spiegel DA, Maher P.

Free Radic Biol Med. 2015 Dec;89:8-19. doi: 10.1016/j.freeradbiomed.2015.07.005. Epub 2015 Jul 9.

32.

Generation and characterization of antibodies against arginine-derived advanced glycation endproducts.

Wang T, Streeter MD, Spiegel DA.

Bioorg Med Chem Lett. 2015 Nov 1;25(21):4881-4886. doi: 10.1016/j.bmcl.2015.06.013. Epub 2015 Jun 11.

PMID:
26117561
33.

Chemical probes reveal an extraseptal mode of cross-linking in Staphylococcus aureus.

Gautam S, Kim T, Spiegel DA.

J Am Chem Soc. 2015 Jun 17;137(23):7441-7. doi: 10.1021/jacs.5b02972. Epub 2015 Jun 2.

PMID:
26035224
34.

Salvage Options in the Cerebral Palsy Hip: A Systematic Review.

Kolman SE, Ruzbarsky JJ, Spiegel DA, Baldwin KD.

J Pediatr Orthop. 2016 Sep;36(6):645-50. doi: 10.1097/BPO.0000000000000501. Review.

PMID:
25887836
35.

Community-acquired Methicillin-resistant Staphylococcus aureus Musculoskeletal Infections: Emerging Trends Over the Past Decade.

Sarkissian EJ, Gans I, Gunderson MA, Myers SH, Spiegel DA, Flynn JM.

J Pediatr Orthop. 2016 Apr-May;36(3):323-7. doi: 10.1097/BPO.0000000000000439.

PMID:
25785593
36.

Deficiencies in the availability of essential musculoskeletal surgical services at 883 health facilities in 24 low- and lower-middle-income countries.

Spiegel DA, Nduaguba A, Cherian MN, Monono M, Kelley ET.

World J Surg. 2015 Jun;39(6):1421-32. doi: 10.1007/s00268-015-2971-2.

PMID:
25663008
37.

Surgical Care and Health Systems.

Spiegel DA, Misra M, Bendix P, Hagander L, Bickler SW, Saleh CO, Ekeke-Monono M, Baah-Odoom D, Caldwell A, Irons B, Amir S, Taylor R, Layne M, Hailu H, Awais SM, Price RR, Crockett S, Islam M; Health Systems Strengthening Working Group of the Global Initiative for Emergency and Essential Surgical Care.

World J Surg. 2015 Sep;39(9):2132-9. doi: 10.1007/s00268-014-2928-x. Review.

PMID:
25561195
38.

Chemically synthesized molecules with the targeting and effector functions of antibodies.

McEnaney PJ, Fitzgerald KJ, Zhang AX, Douglass EF Jr, Shan W, Balog A, Kolesnikova MD, Spiegel DA.

J Am Chem Soc. 2014 Dec 31;136(52):18034-43. doi: 10.1021/ja509513c. Epub 2014 Dec 16.

39.

Click-coated, heparinized, decellularized vascular grafts.

Dimitrievska S, Cai C, Weyers A, Balestrini JL, Lin T, Sundaram S, Hatachi G, Spiegel DA, Kyriakides TR, Miao J, Li G, Niklason LE, Linhardt RJ.

Acta Biomater. 2015 Feb;13:177-87. doi: 10.1016/j.actbio.2014.11.015. Epub 2014 Nov 20.

40.

Illuminating HIV gp120-Ligand Recognition through Computationally-Driven Optimization of Antibody-Recruiting Molecules.

Parker CG, Dahlgren MK, Tao RN, Li DT, Douglass EF Jr, Shoda T, Jawanda N, Spasov KA, Lee S, Zhou N, Domaoal RA, Sutton RE, Anderson KS, Jorgensen WL, Krystal M, Spiegel DA.

Chem Sci. 2014 Jun 1;5(6):2311-2317.

41.

The World Health Organization's action plan on the road traffic injury pandemic: is there any action for orthopaedic trauma surgeons?

Moroz PJ, Spiegel DA.

J Orthop Trauma. 2014;28 Suppl 1:S11-4. doi: 10.1097/BOT.0000000000000105. Review.

PMID:
24857989
42.

CORR Insights®: Results of clubfoot management using the Ponseti method: do the details matter? A systematic review.

Spiegel DA.

Clin Orthop Relat Res. 2014 May;472(5):1617-8. doi: 10.1007/s11999-014-3522-0. Epub 2014 Feb 19. No abstract available.

43.

Risk factors and complications in hip reconstruction for nonambulatory patients with cerebral palsy.

Ruzbarsky JJ, Beck NA, Baldwin KD, Sankar WN, Flynn JM, Spiegel DA.

J Child Orthop. 2013 Dec;7(6):487-500. doi: 10.1007/s11832-013-0536-1. Epub 2013 Oct 15.

44.

The Ponseti method in the treatment of children with idiopathic clubfoot presenting between five and ten years of age.

Banskota B, Banskota AK, Regmi R, Rajbhandary T, Shrestha OP, Spiegel DA.

Bone Joint J. 2013 Dec;95-B(12):1721-5. doi: 10.1302/0301-620X.95B12.32173.

PMID:
24293606
45.

What's new in orthopaedic rehabilitation.

Baldwin K, Yannascoli SM, Namdari S, Spiegel DA, Keenan MA.

J Bone Joint Surg Am. 2013 Nov 20;95(22):2071-7. doi: 10.2106/JBJS.M.01037. Review. No abstract available.

PMID:
24257670
46.

Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler.

Perry RJ, Kim T, Zhang XM, Lee HY, Pesta D, Popov VB, Zhang D, Rahimi Y, Jurczak MJ, Cline GW, Spiegel DA, Shulman GI.

Cell Metab. 2013 Nov 5;18(5):740-8. doi: 10.1016/j.cmet.2013.10.004.

47.

Exploring binding and effector functions of natural human antibodies using synthetic immunomodulators.

Jakobsche CE, Parker CG, Tao RN, Kolesnikova MD, Douglass EF Jr, Spiegel DA.

ACS Chem Biol. 2013 Nov 15;8(11):2404-11. doi: 10.1021/cb4004942. Epub 2013 Sep 20.

48.

Do routine radiographs within the first two years following pediatric posterior spinal fusion prompt revision surgery?

Garcia GH, Park MJ, Baldwin K, Flynn J, Spiegel DA.

Spine (Phila Pa 1976). 2013 Dec 1;38(25):2216-20. doi: 10.1097/BRS.0000000000000018.

PMID:
24048089
49.

A "turn-on" fluorescent sensor for methylglyoxal.

Wang T, Douglass EF Jr, Fitzgerald KJ, Spiegel DA.

J Am Chem Soc. 2013 Aug 21;135(33):12429-33. doi: 10.1021/ja406077j. Epub 2013 Aug 9.

PMID:
23931147
50.

Adjunctive vancomycin powder in pediatric spine surgery is safe.

Gans I, Dormans JP, Spiegel DA, Flynn JM, Sankar WN, Campbell RM, Baldwin KD.

Spine (Phila Pa 1976). 2013 Sep 1;38(19):1703-7. doi: 10.1097/BRS.0b013e31829e05d3.

PMID:
23759805

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