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Items: 1 to 50 of 101

1.

Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS.

Ni Z, Sousa BC, Colombo S, Afonso CB, Melo T, Pitt AR, Spickett CM, Domingues P, Domingues MR, Fedorova M, Criscuolo A.

Free Radic Biol Med. 2019 Jun 15. pii: S0891-5849(19)30347-8. doi: 10.1016/j.freeradbiomed.2019.06.013. [Epub ahead of print]

PMID:
31212065
2.

Short-chain lipid peroxidation products form covalent adducts with pyruvate kinase and inhibit its activity in vitro and in breast cancer cells.

Sousa BC, Ahmed T, Dann WL, Ashman J, Guy A, Durand T, Pitt AR, Spickett CM.

Free Radic Biol Med. 2019 Jun 5. pii: S0891-5849(19)30341-7. doi: 10.1016/j.freeradbiomed.2019.05.028. [Epub ahead of print]

3.

SMA-PAGE: A new method to examine complexes of membrane proteins using SMALP nano-encapsulation and native gel electrophoresis.

Pollock NL, Rai M, Simon KS, Hesketh SJ, Teo ACK, Parmar M, Sridhar P, Collins R, Lee SC, Stroud ZN, Bakker SE, Muench SP, Barton CH, Hurlbut G, Roper DI, Smith CJI, Knowles TJ, Spickett CM, East JM, Postis VLG, Dafforn TR.

Biochim Biophys Acta Biomembr. 2019 May 28;1861(8):1437-1445. doi: 10.1016/j.bbamem.2019.05.011. [Epub ahead of print]

PMID:
31150633
4.

The interaction of silver(II) complexes with biological macromolecules and antioxidants.

Trotter KD, Owojaiye O, Meredith SP, Keating PE, Spicer MD, Reglinski J, Spickett CM.

Biometals. 2019 May 16. doi: 10.1007/s10534-019-00198-0. [Epub ahead of print]

PMID:
31098734
5.

Epitope mapping and characterization of 4-hydroxy-2-nonenal modified-human serum albumin using two different polyclonal antibodies.

Campos-Pinto I, Méndez L, Schouten J, Wilkins J, Fedorova M, Pitt AR, Davis P, Spickett CM.

Free Radic Biol Med. 2019 May 7. pii: S0891-5849(19)30354-5. doi: 10.1016/j.freeradbiomed.2019.05.008. [Epub ahead of print]

6.

Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration.

Rossin D, Dias IHK, Solej M, Milic I, Pitt AR, Iaia N, Scoppapietra L, Devitt A, Nano M, Degiuli M, Volante M, Caccia C, Leoni V, Griffiths HR, Spickett CM, Poli G, Biasi F.

Free Radic Biol Med. 2019 May 20;136:35-44. doi: 10.1016/j.freeradbiomed.2019.03.020. Epub 2019 Mar 23.

PMID:
30910555
7.

Analysis of SMALP co-extracted phospholipids shows distinct membrane environments for three classes of bacterial membrane protein.

Teo ACK, Lee SC, Pollock NL, Stroud Z, Hall S, Thakker A, Pitt AR, Dafforn TR, Spickett CM, Roper DI.

Sci Rep. 2019 Feb 12;9(1):1813. doi: 10.1038/s41598-018-37962-0.

8.

Lipoproteins as targets and markers of lipoxidation.

Afonso CB, Spickett CM.

Redox Biol. 2018 Dec 6:101066. doi: 10.1016/j.redox.2018.101066. [Epub ahead of print] Review.

9.

PARP1 promoter links cell cycle progression with adaptation to oxidative environment.

Pietrzak J, Spickett CM, Płoszaj T, Virág L, Robaszkiewicz A.

Redox Biol. 2018 Sep;18:1-5. doi: 10.1016/j.redox.2018.05.017. Epub 2018 Jun 2. Review.

10.

Reprint of: Proteomics in cardiovascular diseases: Unveiling sex and gender differences in the era of precision medicine.

Baetta R, Pontremoli M, Fernandez AM, Spickett CM, Banfi C.

J Proteomics. 2018 Apr 30;178:57-72. doi: 10.1016/j.jprot.2018.03.017. Epub 2018 Apr 3. Review.

PMID:
29622522
11.

A mass spectrometry approach for the identification and localization of small aldehyde modifications of proteins.

Afonso CB, Sousa BC, Pitt AR, Spickett CM.

Arch Biochem Biophys. 2018 May 15;646:38-45. doi: 10.1016/j.abb.2018.03.026. Epub 2018 Mar 23.

PMID:
29580947
12.

A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells.

Knight AR, Taylor EL, Lukaszewski R, Jensen KT, Jones HE, Carré JE, Isupov MN, Littlechild JA, Bailey SJ, Brewer E, McDonald TJ, Pitt AR, Spickett CM, Winyard PG.

Free Radic Biol Med. 2018 May 20;120:246-254. doi: 10.1016/j.freeradbiomed.2018.03.026. Epub 2018 Mar 17.

PMID:
29555590
13.

The effect of HOCl-induced modifications on phosphatase and tensin homologue (PTEN) structure and function.

Verrastro I, Tveen-Jensen K, Spickett CM, Pitt AR.

Free Radic Res. 2018 Feb;52(2):232-247. doi: 10.1080/10715762.2018.1424333. Epub 2018 Jan 22.

PMID:
29298524
14.

Proteomics in cardiovascular diseases: Unveiling sex and gender differences in the era of precision medicine.

Baetta R, Pontremoli M, Martinez Fernandez A, Spickett CM, Banfi C.

J Proteomics. 2018 Feb 20;173:62-76. doi: 10.1016/j.jprot.2017.11.012. Epub 2017 Nov 24.

PMID:
29180046
15.

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kračun D, Krause KH, Křen V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milković L, Miranda-Vizuete A, Mojović M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavićević A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanić V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçın AS, Yelisyeyeva O, Žarković N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A.

Redox Biol. 2018 Apr;14:694-696. doi: 10.1016/j.redox.2017.10.001. Epub 2017 Oct 26. No abstract available.

16.

Posterior Vitreous Detachment and the Posterior Hyaloid Membrane.

Fincham GS, James S, Spickett C, Hollingshead M, Thrasivoulou C, Poulson AV, McNinch A, Richards A, Snead D, Limb GA, Snead MP.

Ophthalmology. 2018 Feb;125(2):227-236. doi: 10.1016/j.ophtha.2017.08.001. Epub 2017 Sep 1.

17.

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kračun D, Krause KH, Křen V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milković L, Miranda-Vizuete A, Mojović M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavićević A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanić V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçın AS, Yelisyeyeva O, Žarković N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A.

Redox Biol. 2017 Oct;13:94-162. doi: 10.1016/j.redox.2017.05.007. Epub 2017 May 18. Review. Erratum in: Redox Biol. 2018 Apr;14 :694-696.

18.

Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds.

Sousa BC, Pitt AR, Spickett CM.

Free Radic Biol Med. 2017 Oct;111:294-308. doi: 10.1016/j.freeradbiomed.2017.02.003. Epub 2017 Feb 10. Review.

PMID:
28192230
19.

Anti-myeloperoxidase antibodies attenuate the monocyte response to LPS and shape macrophage development.

Popat RJ, Hakki S, Thakker A, Coughlan AM, Watson J, Little MA, Spickett CM, Lavender P, Afzali B, Kemper C, Robson MG.

JCI Insight. 2017 Jan 26;2(2):e87379. doi: 10.1172/jci.insight.87379.

20.

Deep Intronic Sequence Variants in COL2A1 Affect the Alternative Splicing Efficiency of Exon 2, and May Confer a Risk for Rhegmatogenous Retinal Detachment.

Spickett C, Hysi P, Hammond CJ, Prescott A, Fincham GS, Poulson AV, McNinch AM, Richards AJ, Snead MP.

Hum Mutat. 2016 Oct;37(10):1085-96. doi: 10.1002/humu.23050. Epub 2016 Aug 21.

PMID:
27406592
21.

Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins.

Verrastro I, Tveen-Jensen K, Woscholski R, Spickett CM, Pitt AR.

Free Radic Biol Med. 2016 Jan;90:24-34. doi: 10.1016/j.freeradbiomed.2015.11.004. Epub 2015 Nov 10.

22.

Lack of association between TDP-43 pathology and tau mis-splicing in Alzheimer's disease.

Niblock M, Hortobágyi T, Troakes C, Al-Sarraj S, Spickett C, Jones R, Shaw CE, Gallo JM.

Neurobiol Aging. 2016 Jan;37:45-46. doi: 10.1016/j.neurobiolaging.2015.09.022. Epub 2015 Oct 9.

23.

Targeted mass spectrometry methods for detecting oxidative post-translational modifications.

Tveen-Jensen K, Reis A, Spickett CM, Pitt AR.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S52-3. doi: 10.1016/j.freeradbiomed.2014.10.825. Epub 2014 Dec 10.

PMID:
26461406
24.

Mapping nitro-tyrosine modifications in fibrinogen by mass spectrometry as a biomarker for inflammatory disease.

Meredith S, Parekh G, Towler J, Schouten J, Davis P, Griffiths H, Spickett C.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S50. doi: 10.1016/j.freeradbiomed.2014.10.819. Epub 2014 Dec 10.

PMID:
26461400
25.

Detection and quantification of protein oxidation in sarcopenic models: a mass spectrometry study.

Pasha S, Tveen Jensen K, Pitt AR, Spickett CM.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S44. doi: 10.1016/j.freeradbiomed.2014.10.800. Epub 2014 Dec 10.

PMID:
26461380
26.

Oxidised LDL lipids, statins and a blood-brain barrier.

Griffiths H, Irundika D, Lip G, Spickett C, Polidori C.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S15-6. doi: 10.1016/j.freeradbiomed.2014.10.591. Epub 2014 Dec 10.

PMID:
26461292
27.

Copper complexes as a source of redox active MRI contrast agents.

Dunbar L, Sowden RJ, Trotter KD, Taylor MK, Smith D, Kennedy AR, Reglinski J, Spickett CM.

Biometals. 2015 Oct;28(5):903-12. doi: 10.1007/s10534-015-9875-3. Epub 2015 Aug 9.

28.

The hypotensive effect of acute and chronic AMP-activated protein kinase activation in normal and hyperlipidemic mice.

Greig FH, Ewart MA, McNaughton E, Cooney J, Spickett CM, Kennedy S.

Vascul Pharmacol. 2015 Nov;74:93-102. doi: 10.1016/j.vph.2015.07.010. Epub 2015 Jul 18.

29.

Protein lipoxidation: Detection strategies and challenges.

Aldini G, Domingues MR, Spickett CM, Domingues P, Altomare A, Sánchez-Gómez FJ, Oeste CL, Pérez-Sala D.

Redox Biol. 2015 Aug;5:253-266. doi: 10.1016/j.redox.2015.05.003. Epub 2015 May 21. Review.

30.

Interfacing low-energy SAW nebulization with Liquid Chromatography-Mass Spectrometry for the analysis of biological samples.

Tveen-Jensen K, Gesellchen F, Wilson R, Spickett CM, Cooper JM, Pitt AR.

Sci Rep. 2015 May 15;5:9736. doi: 10.1038/srep09736.

31.

Special issue on "Analytical methods for the detection of oxidized biomolecules and antioxidants".

Parsons BJ, Spickett CM.

Free Radic Res. 2015 May;49(5):473-6. doi: 10.3109/10715762.2015.1024678. Epub 2015 Apr 17. No abstract available.

PMID:
25884783
32.

Mass spectrometry-based methods for identifying oxidized proteins in disease: advances and challenges.

Verrastro I, Pasha S, Jensen KT, Pitt AR, Spickett CM.

Biomolecules. 2015 Apr 14;5(2):378-411. doi: 10.3390/biom5020378. Review.

33.

Exploring oxidative modifications of tyrosine: an update on mechanisms of formation, advances in analysis and biological consequences.

Houée-Lévin C, Bobrowski K, Horakova L, Karademir B, Schöneich C, Davies MJ, Spickett CM.

Free Radic Res. 2015 Apr;49(4):347-73. doi: 10.3109/10715762.2015.1007968. Epub 2015 Mar 27. Review.

PMID:
25812585
34.

Oxidative lipidomics coming of age: advances in analysis of oxidized phospholipids in physiology and pathology.

Spickett CM, Pitt AR.

Antioxid Redox Signal. 2015 Jun 20;22(18):1646-66. doi: 10.1089/ars.2014.6098. Epub 2015 Mar 26. Review.

35.

Ophthalmic and molecular genetic findings in Kniest dysplasia.

Sergouniotis PI, Fincham GS, McNinch AM, Spickett C, Poulson AV, Richards AJ, Snead MP.

Eye (Lond). 2015 Apr;29(4):475-82. doi: 10.1038/eye.2014.334. Epub 2015 Jan 16.

36.

Differential effects of chlorinated and oxidized phospholipids in vascular tissue: implications for neointima formation.

Greig FH, Hutchison L, Spickett CM, Kennedy S.

Clin Sci (Lond). 2015 May;128(9):579-92. doi: 10.1042/CS20140578.

PMID:
25524654
37.

Top-down lipidomics of low density lipoprotein reveal altered lipid profiles in advanced chronic kidney disease.

Reis A, Rudnitskaya A, Chariyavilaskul P, Dhaun N, Melville V, Goddard J, Webb DJ, Pitt AR, Spickett CM.

J Lipid Res. 2015 Feb;56(2):413-22. doi: 10.1194/jlr.M055624. Epub 2014 Nov 25.

38.

Identification and relative quantification of tyrosine nitration in a model peptide using two-dimensional infrared spectroscopy.

Rezende Valim L, Davies JA, Tveen Jensen K, Guo R, Willison KR, Spickett CM, Pitt AR, Klug DR.

J Phys Chem B. 2014 Nov 13;118(45):12855-64. doi: 10.1021/jp509053q. Epub 2014 Nov 4.

39.

Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation.

Dias IH, Mistry J, Fell S, Reis A, Spickett CM, Polidori MC, Lip GY, Griffiths HR.

Free Radic Biol Med. 2014 Oct;75:48-59. doi: 10.1016/j.freeradbiomed.2014.07.012. Epub 2014 Jul 15.

40.

HOCl-modified phosphatidylcholines induce apoptosis and redox imbalance in HUVEC-ST cells.

Robaszkiewicz A, Bartosz G, Pitt AR, Thakker A, Armstrong RA, Spickett CM, Soszyński M.

Arch Biochem Biophys. 2014 Apr 15;548:1-10. doi: 10.1016/j.abb.2014.02.013. Epub 2014 Mar 4.

PMID:
24607806
41.

Detection of phosphatidylserine with a modified polar head group in human keratinocytes exposed to the radical generator AAPH.

Maciel E, Neves BM, Santinha D, Reis A, Domingues P, Teresa Cruz M, Pitt AR, Spickett CM, Domingues MR.

Arch Biochem Biophys. 2014 Apr 15;548:38-45. doi: 10.1016/j.abb.2014.02.002. Epub 2014 Feb 20.

PMID:
24560783
42.

The lipid peroxidation product 4-hydroxy-2-nonenal: Advances in chemistry and analysis.

Spickett CM.

Redox Biol. 2013 Jan 21;1:145-52. doi: 10.1016/j.redox.2013.01.007. Review.

43.

Post-translational modifications and mass spectrometry detection.

Silva AMN, Vitorino R, Domingues MRM, Spickett CM, Domingues P.

Free Radic Biol Med. 2013 Dec;65:925-941. doi: 10.1016/j.freeradbiomed.2013.08.184. Epub 2013 Aug 31. Review.

PMID:
24002012
44.

Lipoxidation adducts with peptides and proteins: deleterious modifications or signaling mechanisms?

Domingues RM, Domingues P, Melo T, Pérez-Sala D, Reis A, Spickett CM.

J Proteomics. 2013 Oct 30;92:110-31. doi: 10.1016/j.jprot.2013.06.004. Epub 2013 Jun 14. Review.

PMID:
23770299
45.

Impairment of calcium ATPases by high glucose and potential pharmacological protection.

Horáková L, Strosova MK, Spickett CM, Blaskovic D.

Free Radic Res. 2013 Aug;47 Suppl 1:81-92. doi: 10.3109/10715762.2013.807923. Epub 2013 Jun 25. Review.

PMID:
23710650
46.

A comparison of five lipid extraction solvent systems for lipidomic studies of human LDL.

Reis A, Rudnitskaya A, Blackburn GJ, Mohd Fauzi N, Pitt AR, Spickett CM.

J Lipid Res. 2013 Jul;54(7):1812-24. doi: 10.1194/jlr.M034330. Epub 2013 May 13.

47.

Reporter ion-based mass spectrometry approaches for the detection of non-enzymatic protein modifications in biological samples.

Tveen-Jensen K, Reis A, Mouls L, Pitt AR, Spickett CM.

J Proteomics. 2013 Oct 30;92:71-9. doi: 10.1016/j.jprot.2013.03.033. Epub 2013 Apr 17.

PMID:
23603107
48.

Specific lipidome signatures in central nervous system from methionine-restricted mice.

Jové M, Ayala V, Ramírez-Núñez O, Naudí A, Cabré R, Spickett CM, Portero-Otín M, Pamplona R.

J Proteome Res. 2013 Jun 7;12(6):2679-89. doi: 10.1021/pr400064a. Epub 2013 Apr 30.

PMID:
23590626
49.

Use of narrow mass-window, high-resolution extracted product ion chromatograms for the sensitive and selective identification of protein modifications.

Spickett CM, Reis A, Pitt AR.

Anal Chem. 2013 May 7;85(9):4621-7. doi: 10.1021/ac400131f. Epub 2013 Apr 23.

PMID:
23534669
50.

Reactions of copper macrocycles with antioxidants and HOCl: potential for biological redox sensing.

Sowden RJ, Trotter KD, Dunbar L, Craig G, Erdemli O, Spickett CM, Reglinski J.

Biometals. 2013 Feb;26(1):85-96. doi: 10.1007/s10534-012-9596-9. Epub 2012 Nov 18.

PMID:
23160798

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