Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 456


Inhibition of the Cytolytic Protein Perforin Prevents Rejection of Transplanted Bone Marrow Stem Cells in Vivo.

Spicer JA, Miller CK, O'Connor PD, Jose J, Giddens AC, Jaiswal JK, Jamieson SMF, Bull MR, Denny WA, Akhlaghi H, Trapani JA, Hill GR, Chang K, Gartlan KH.

J Med Chem. 2019 Sep 26. doi: 10.1021/acs.jmedchem.9b00881. [Epub ahead of print]


The rapid scale up of medical education in Ethiopia: Medical student experiences and the role of e-learning at Addis Ababa University.

Kelly CM, Vins H, Spicer JO, Mengistu BS, Wilson DR, Derbew M, Bekele A, Mariam DH, Del Rio C, Kempker RR, Comeau DL, Blumberg HM.

PLoS One. 2019 Sep 5;14(9):e0221989. doi: 10.1371/journal.pone.0221989. eCollection 2019.


Casting A Wide Net On Surgery: The Central Role of Neutrophil Extracellular Traps.

Eustache JH, Tohme S, Milette S, Rayes RF, Tsung A, Spicer JD.

Ann Surg. 2019 Aug 27. doi: 10.1097/SLA.0000000000003586. [Epub ahead of print]


Gram-Negative Pneumonia Augments Non-Small Cell Lung Cancer Metastasis through Host Toll-like Receptor 4 Activation.

Gowing SD, Chow SC, Cools-Lartigue JJ, Chen CB, Najmeh S, Goodwin-Wilson M, Jiang HY, Bourdeau F, Beauchamp A, Angers I, Giannias B, Spicer JD, Rousseau S, Qureshi ST, Ferri LE.

J Thorac Oncol. 2019 Aug 2. pii: S1556-0864(19)30653-7. doi: 10.1016/j.jtho.2019.07.023. [Epub ahead of print]


Cytotoxic Chemotherapy as an Immune Stimulus: A Molecular Perspective on Turning Up the Immunological Heat on Cancer.

Opzoomer JW, Sosnowska D, Anstee JE, Spicer JF, Arnold JN.

Front Immunol. 2019 Jul 17;10:1654. doi: 10.3389/fimmu.2019.01654. eCollection 2019. Review.


Moderate reductions in dissolved oxygen may compromise performance in an ecologically-important estuarine invertebrate.

Collins M, Tills O, Turner LM, Clark MS, Spicer JI, Truebano M.

Sci Total Environ. 2019 Nov 25;693:133444. doi: 10.1016/j.scitotenv.2019.07.250. Epub 2019 Jul 17.


Primary tumors induce neutrophil extracellular traps with targetable metastasis promoting effects.

Rayes RF, Mouhanna JG, Nicolau I, Bourdeau F, Giannias B, Rousseau S, Quail D, Walsh L, Sangwan V, Bertos N, Cools-Lartigue J, Ferri LE, Spicer JD.

JCI Insight. 2019 Jul 25;5. pii: 128008. doi: 10.1172/jci.insight.128008.


Quantifying susceptibility of marine invertebrate biocomposites to dissolution in reduced pH.

Chadwick M, Harper EM, Lemasson A, Spicer JI, Peck LS.

R Soc Open Sci. 2019 Jun 5;6(6):190252. doi: 10.1098/rsos.190252. eCollection 2019 Jun.


Should UK primary care be an early adopter of genomic medicine?

Dickenson D, Rafi I, Spicer J, Papanikitas A.

Br J Gen Pract. 2019 Jul;69(684):330-331. doi: 10.3399/bjgp19X704201. No abstract available.


Physiological diversity, biodiversity patterns and global climate change: testing key hypotheses involving temperature and oxygen.

Spicer JI, Morley SA, Bozinovic F.

Philos Trans R Soc Lond B Biol Sci. 2019 Aug 5;374(1778):20190032. doi: 10.1098/rstb.2019.0032. Epub 2019 Jun 17.


Will giant polar amphipods be first to fare badly in an oxygen-poor ocean? Testing hypotheses linking oxygen to body size.

Spicer JI, Morley SA.

Philos Trans R Soc Lond B Biol Sci. 2019 Aug 5;374(1778):20190034. doi: 10.1098/rstb.2019.0034. Epub 2019 Jun 17.


Ambulatory Blood Pressure Trajectory and Perceived Stress in Relation to Birth Outcomes in Healthy Pregnant Adolescents.

Spicer J, Giesbrecht GF, Aboelela S, Lee S, Liu G, Monk C.

Psychosom Med. 2019 Jun;81(5):464-476. doi: 10.1097/PSY.0000000000000698.


Immune mediator expression signatures are associated with improved outcome in ovarian carcinoma.

Nakamura M, Bax HJ, Scotto D, Souri EA, Sollie S, Harris RJ, Hammar N, Walldius G, Winship A, Ghosh S, Montes A, Spicer JF, Van Hemelrijck M, Josephs DH, Lacy KE, Tsoka S, Karagiannis SN.

Oncoimmunology. 2019 Mar 28;8(6):e1593811. doi: 10.1080/2162402X.2019.1593811. eCollection 2019.


The importance of inter-individual variation in predicting species' responses to global change drivers.

Guscelli E, Spicer JI, Calosi P.

Ecol Evol. 2019 Mar 28;9(8):4327-4339. doi: 10.1002/ece3.4810. eCollection 2019 Apr.


AllergoOncology: Expression platform development and functional profiling of an anti-HER2 IgE antibody.

Ilieva KM, Fazekas-Singer J, Bax HJ, Crescioli S, Montero-Morales L, Mele S, Sow HS, Stavraka C, Josephs DH, Spicer JF, Steinkellner H, Jensen-Jarolim E, Tutt ANJ, Karagiannis SN.

Allergy. 2019 Oct;74(10):1985-1989. doi: 10.1111/all.13818. Epub 2019 May 27. No abstract available.


IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural states.

Pellizzari G, Hoskin C, Crescioli S, Mele S, Gotovina J, Chiaruttini G, Bianchini R, Ilieva K, Bax HJ, Papa S, Lacy KE, Jensen-Jarolim E, Tsoka S, Josephs DH, Spicer JF, Karagiannis SN.

EBioMedicine. 2019 May;43:67-81. doi: 10.1016/j.ebiom.2019.03.080. Epub 2019 Apr 5.


Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma.

Khair DO, Bax HJ, Mele S, Crescioli S, Pellizzari G, Khiabany A, Nakamura M, Harris RJ, French E, Hoffmann RM, Williams IP, Cheung A, Thair B, Beales CT, Touizer E, Signell AW, Tasnova NL, Spicer JF, Josephs DH, Geh JL, MacKenzie Ross A, Healy C, Papa S, Lacy KE, Karagiannis SN.

Front Immunol. 2019 Mar 19;10:453. doi: 10.3389/fimmu.2019.00453. eCollection 2019. Review.


Commentary: The path to prophylaxis for predictable palpitations.

Spicer JD.

J Thorac Cardiovasc Surg. 2019 Jun;157(6):2500-2501. doi: 10.1016/j.jtcvs.2019.02.021. Epub 2019 Feb 19. No abstract available.


What does the mind learn? A comparison of human and machine learning representations.

Spicer J, Sanborn AN.

Curr Opin Neurobiol. 2019 Apr;55:97-102. doi: 10.1016/j.conb.2019.02.004. Epub 2019 Mar 11. Review.


Endoscopic Submucosal Dissection for Esophageal Adenocarcinoma: A North American Perspective.

Bouchard P, Molina JC, Cools-Lartigue J, Spicer J, Mueller CL, Ferri LE.

J Gastrointest Surg. 2019 Jun;23(6):1087-1094. doi: 10.1007/s11605-018-04093-w. Epub 2019 Jan 31.


Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1-2 trial.

de Bono JS, Concin N, Hong DS, Thistlethwaite FC, Machiels JP, Arkenau HT, Plummer R, Jones RH, Nielsen D, Windfeld K, Ghatta S, Slomovitz BM, Spicer JF, Yachnin J, Ang JE, Mau-Sørensen PM, Forster MD, Collins D, Dean E, Rangwala RA, Lassen U.

Lancet Oncol. 2019 Mar;20(3):383-393. doi: 10.1016/S1470-2045(18)30859-3. Epub 2019 Feb 8.


Registry-Based Medical Research: Data Dredging or Value Building to Quality of Care?

Mulder DS, Spicer J.

Ann Thorac Surg. 2019 Jul;108(1):274-282. doi: 10.1016/j.athoracsur.2018.12.060. Epub 2019 Feb 8. Review.


SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer.

Xue Y, Meehan B, Fu Z, Wang XQD, Fiset PO, Rieker R, Levins C, Kong T, Zhu X, Morin G, Skerritt L, Herpel E, Venneti S, Martinez D, Judkins AR, Jung S, Camilleri-Broet S, Gonzalez AV, Guiot MC, Lockwood WW, Spicer JD, Agaimy A, Pastor WA, Dostie J, Rak J, Foulkes WD, Huang S.

Nat Commun. 2019 Feb 4;10(1):557. doi: 10.1038/s41467-019-08380-1.


Synthesis and Evaluation of Imidazo[1,2-a]pyridine Analogues of the ZSTK474 Class of Phosphatidylinositol 3-Kinase Inhibitors.

Gamage SA, Spicer JA, Tsang KY, O'Connor PD, Flanagan JU, Lee WJ, Dickson JMJ, Shepherd PR, Denny WA, Rewcastle GW.

Chem Asian J. 2019 Apr 15;14(8):1249-1261. doi: 10.1002/asia.201801762. Epub 2019 Mar 12.


The innate immune architecture of lung tumors and its implication in disease progression.

Milette S, Fiset PO, Walsh LA, Spicer JD, Quail DF.

J Pathol. 2019 Apr;247(5):589-605. doi: 10.1002/path.5241. Review.


A high-throughput and open-source platform for embryo phenomics.

Tills O, Spicer JI, Grimmer A, Marini S, Jie VW, Tully E, Rundle SD.

PLoS Biol. 2018 Dec 13;16(12):e3000074. doi: 10.1371/journal.pbio.3000074. eCollection 2018 Dec.


Prognostic value of neutrophil to lymphocyte ratio in lung metastasectomy for colorectal cancer.

Renaud S, Seitlinger J, St-Pierre D, Garfinkle R, Al Lawati Y, Guerrera F, Ruffini E, Falcoz PE, Massard G, Ferri L, Spicer J.

Eur J Cardiothorac Surg. 2019 May 1;55(5):948-955. doi: 10.1093/ejcts/ezy388.


Enhanced recovery after pulmonary surgery.

Eustache J, Ferri LE, Feldman LS, Lee L, Spicer JD.

J Thorac Dis. 2018 Nov;10(Suppl 32):S3755-S3760. doi: 10.21037/jtd.2018.09.61. Review.


Effects of oil and global environmental drivers on two keystone marine invertebrates.

Arnberg M, Calosi P, Spicer JI, Taban IC, Bamber SD, Westerlund S, Vingen S, Baussant T, Bechmann RK, Dupont S.

Sci Rep. 2018 Nov 26;8(1):17380. doi: 10.1038/s41598-018-35623-w.


Experimental characterization and physics-based modeling of the temperature-dependent diffuse reflectance of plasma-sprayed Nd2Zr2O7 in the near to short-wave infrared.

Brupbacher MC, Zhang D, Buchta WM, Montalbano TJ, Caruso KS, Airola MB, Brown DM, Thomas ME, Spicer JB.

Appl Opt. 2018 Sep 20;57(27):7782-7792. doi: 10.1364/AO.57.007782.


Perforin inhibition protects from lethal endothelial damage during fulminant viral hepatitis.

Welz M, Eickhoff S, Abdullah Z, Trebicka J, Gartlan KH, Spicer JA, Demetris AJ, Akhlaghi H, Anton M, Manske K, Zehn D, Nieswandt B, Kurts C, Trapani JA, Knolle P, Wohlleber D, Kastenmüller W.

Nat Commun. 2018 Nov 15;9(1):4805. doi: 10.1038/s41467-018-07213-x.


Differential Survival Characteristics of Sarcomatoid Subtype in Biphasic Pleural Mesothelioma.

Harling L, Kolokotroni SM, Nair A, Smelt J, King J, Routledge T, Spicer J, Ng W, Bille A.

Ann Thorac Surg. 2019 Mar;107(3):929-935. doi: 10.1016/j.athoracsur.2018.09.019. Epub 2018 Oct 30.


Delayed adverse events in phase I trials of molecularly targeted and cytotoxic agents.

Jordan EJ, Spicer J, Sarker D.

Oncotarget. 2018 Sep 21;9(74):33961-33971. doi: 10.18632/oncotarget.26104. eCollection 2018 Sep 21.


Pharmacokinetic Effects and Safety of Olaparib Administered with Endocrine Therapy: A Phase I Study in Patients with Advanced Solid Tumours.

Plummer R, Verheul HM, De Vos FYFL, Leunen K, Molife LR, Rolfo C, Grundtvig-Sørensen P, De Grève J, Rottey S, Jerusalem G, Italiano A, Spicer J, Dirix L, Goessl C, Birkett J, Spencer S, Learoyd M, Bailey C, Dean E.

Adv Ther. 2018 Nov;35(11):1945-1964. doi: 10.1007/s12325-018-0804-z. Epub 2018 Oct 15.


Multimodality Therapy for N2 Non-Small Cell Lung Cancer: An Evolving Paradigm.

Spicer JD, Shewale JB, Nelson DB, Mitchell KG, Bott MJ, Vallières E, Wilshire CL, Vaporciyan AA, Swisher SG, Jones DR, Darling GE, Sepesi B.

Ann Thorac Surg. 2019 Jan;107(1):277-284. doi: 10.1016/j.athoracsur.2018.07.033. Epub 2018 Sep 15.


Palladium nanoparticle formation processes in fluoropolymers by thermal decomposition of organometallic precursors.

Zeng FW, Zhang D, Spicer JB.

Phys Chem Chem Phys. 2018 Oct 7;20(37):24389-24398. doi: 10.1039/c8cp04997a. Epub 2018 Sep 17.


An extended phase Ib study of epertinib, an orally active reversible dual EGFR/HER2 tyrosine kinase inhibitor, in patients with solid tumours.

Arkenau HT, Italiano A, Mak G, Toulmonde M, Baird RD, Garcia-Corbacho J, Plummer R, Flynn M, Forster M, Wilson RH, Tosi D, Adenis A, Donaldson K, Posner J, Kawabata I, Arimura A, Deva S, Spicer J.

Eur J Cancer. 2018 Nov;103:17-23. doi: 10.1016/j.ejca.2018.07.134. Epub 2018 Sep 6.


Developing a Nursing Practice Framework to Align With Strategy.

Spicer JG, Sparacino PSA, Larkin NE.

J Nurs Adm. 2018 Sep;48(9):419-421. doi: 10.1097/NNA.0000000000000663.


A phase I study to assess afatinib in combination with carboplatin or with carboplatin plus paclitaxel in patients with advanced solid tumors.

O'Brien MER, Sarker D, Bhosle J, Thillai K, Yap TA, Uttenreuther-Fischer M, Pemberton K, Jin X, Wiebe S, de Bono J, Spicer J.

Cancer Chemother Pharmacol. 2018 Nov;82(5):757-766. doi: 10.1007/s00280-018-3661-1. Epub 2018 Aug 7.


Evaluating case studies of community-oriented integrated care.

Thomas P, Sachar A, Papanikitas A, While A, Brophy C, Manning C, Mills C, Ruprah-Shah B, Millington-Sanders C, Morris D, Kelley Patterson D, Hill D, McKenzie-Edwards E, Wright F, Carelli F, Shaw F, Vedel I, Spicer J, Wewiora L, Gul M, Kirkbride Ba M, Sadlowski M, Breton M, Banarsee R, Gupta S, Burch T, Kempe T, Tzortziou Brown V, Sanfey J.

London J Prim Care (Abingdon). 2018 May 31;10(4):73-81. doi: 10.1080/17571472.2018.1477455. eCollection 2018.


PATRIOT: A phase I study to assess the tolerability, safety and biological effects of a specific ataxia telangiectasia and Rad3-related (ATR) inhibitor (AZD6738) as a single agent and in combination with palliative radiation therapy in patients with solid tumours.

Dillon MT, Boylan Z, Smith D, Guevara J, Mohammed K, Peckitt C, Saunders M, Banerji U, Clack G, Smith SA, Spicer JF, Forster MD, Harrington KJ.

Clin Transl Radiat Oncol. 2018 Jun 8;12:16-20. doi: 10.1016/j.ctro.2018.06.001. eCollection 2018 Aug.


Anti-Folate Receptor Alpha-Directed Antibody Therapies Restrict the Growth of Triple-negative Breast Cancer.

Cheung A, Opzoomer J, Ilieva KM, Gazinska P, Hoffmann RM, Mirza H, Marlow R, Francesch-Domenech E, Fittall M, Dominguez Rodriguez D, Clifford A, Badder L, Patel N, Mele S, Pellizzari G, Bax HJ, Crescioli S, Petranyi G, Larcombe-Young D, Josephs DH, Canevari S, Figini M, Pinder S, Nestle FO, Gillett C, Spicer JF, Grigoriadis A, Tutt ANJ, Karagiannis SN.

Clin Cancer Res. 2018 Oct 15;24(20):5098-5111. doi: 10.1158/1078-0432.CCR-18-0652. Epub 2018 Aug 1.


Vistusertib (dual m-TORC1/2 inhibitor) in combination with paclitaxel in patients with high-grade serous ovarian and squamous non-small-cell lung cancer.

Basu B, Krebs MG, Sundar R, Wilson RH, Spicer J, Jones R, Brada M, Talbot DC, Steele N, Ingles Garces AH, Brugger W, Harrington EA, Evans J, Hall E, Tovey H, de Oliveira FM, Carreira S, Swales K, Ruddle R, Raynaud FI, Purchase B, Dawes JC, Parmar M, Turner AJ, Tunariu N, Banerjee S, de Bono JS, Banerji U.

Ann Oncol. 2018 Sep 1;29(9):1918-1925. doi: 10.1093/annonc/mdy245.


Anatomical Resections Improve Survival Following Lung Metastasectomy of Colorectal Cancer Harboring KRAS Mutations.

Renaud S, Seitlinger J, Lawati YA, Guerrera F, Falcoz PE, Massard G, Ferri L, Spicer J.

Ann Surg. 2018 May 17. doi: 10.1097/SLA.0000000000002829. [Epub ahead of print]


Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancer.

Traylor M, Walker JL, Corrigan AA, Hernandez MA, Newhouse SJ, Folarin AA, Patel H, Ross PJ, Sanderson JD, Spicer J, Prescott NJ, Mathew CG, Marinaki AM, Lewis CM.

PLoS One. 2018 May 1;13(5):e0188911. doi: 10.1371/journal.pone.0188911. eCollection 2018.


Multivisceral Resection for Locally Advanced Gastric and Gastroesophageal Junction Cancers-11-Year Experience at a High-Volume North American Center.

Molina JC, Al-Hinai A, Gosseling-Tardif A, Bouchard P, Spicer J, Mulder D, Mueller CL, Ferri LE.

J Gastrointest Surg. 2019 Jan;23(1):43-50. doi: 10.1007/s11605-018-3746-5. Epub 2018 Apr 16.


An immunologically relevant rodent model demonstrates safety of therapy using a tumour-specific IgE.

Josephs DH, Nakamura M, Bax HJ, Dodev TS, Muirhead G, Saul L, Karagiannis P, Ilieva KM, Crescioli S, Gazinska P, Woodman N, Lombardelli C, Kareemaghay S, Selkirk C, Lentfer H, Barton C, Canevari S, Figini M, Downes N, Dombrowicz D, Corrigan CJ, Nestle FO, Jones PS, Gould HJ, Blower PJ, Tsoka S, Spicer JF, Karagiannis SN.

Allergy. 2018 Dec;73(12):2328-2341. doi: 10.1111/all.13455. Epub 2018 Oct 8.


Evaluation of Antigen-Conjugated Fluorescent Beads to Identify Antigen-Specific B Cells.

Correa I, Ilieva KM, Crescioli S, Lombardi S, Figini M, Cheung A, Spicer JF, Tutt ANJ, Nestle FO, Karagiannis P, Lacy KE, Karagiannis SN.

Front Immunol. 2018 Mar 23;9:493. doi: 10.3389/fimmu.2018.00493. eCollection 2018.


Entanglement-Based Thermoplastic Shape Memory Polymeric Particles with Photothermal Actuation for Biomedical Applications.

Guo Q, Bishop CJ, Meyer RA, Wilson DR, Olasov L, Schlesinger DE, Mather PT, Spicer JB, Elisseeff JH, Green JJ.

ACS Appl Mater Interfaces. 2018 Apr 25;10(16):13333-13341. doi: 10.1021/acsami.8b01582. Epub 2018 Apr 10.

Supplemental Content

Loading ...
Support Center