Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 66


Abrogation of EMILIN1-β1 integrin interaction promotes experimental colitis and colon carcinogenesis.

Capuano A, Pivetta E, Sartori G, Bosisio G, Favero A, Cover E, Andreuzzi E, Colombatti A, Cannizzaro R, Scanziani E, Minoli L, Bucciotti F, Amor Lopez AI, Gaspardo K, Doliana R, Mongiat M, Spessotto P.

Matrix Biol. 2019 Oct;83:97-115. doi: 10.1016/j.matbio.2019.08.006. Epub 2019 Aug 31.


Multiplex staining depicts the immune infiltrate in colitis-induced colon cancer model.

Pivetta E, Capuano A, Scanziani E, Minoli L, Andreuzzi E, Mongiat M, Baldassarre G, Doliana R, Spessotto P.

Sci Rep. 2019 Sep 2;9(1):12645. doi: 10.1038/s41598-019-49164-3.


Probe-based confocal laser endomicroscopy (pCLE) is a suitable method for extrapulmonary high grade neuroendocrine rectal carcinoma (HGNEC) evaluation.

Cannizzaro R, Maiero S, Fornasarig M, Canzonieri V, Magris R, Guarnieri G, Urbani M, Buonadonna A, Baresic T, Spessotto P.

Onco Targets Ther. 2019 Jun 17;12:4577-4583. doi: 10.2147/OTT.S198034. eCollection 2019.


The Probe Based Confocal Laser Endomicroscopy (pCLE) in Locally Advanced Gastric Cancer: A Powerful Technique for Real-Time Analysis of Vasculature.

Capuano A, Andreuzzi E, Pivetta E, Doliana R, Favero A, Canzonieri V, Maiero S, Fornasarig M, Magris R, Cannizzaro R, Mongiat M, Spessotto P.

Front Oncol. 2019 Jun 13;9:513. doi: 10.3389/fonc.2019.00513. eCollection 2019.


Loss of Multimerin-2 and EMILIN-2 Expression in Gastric Cancer Associate with Altered Angiogenesis.

Andreuzzi E, Capuano A, Pellicani R, Poletto E, Doliana R, Maiero S, Fornasarig M, Magris R, Colombatti A, Cannizzaro R, Spessotto P, Mongiat M.

Int J Mol Sci. 2018 Dec 11;19(12). pii: E3983. doi: 10.3390/ijms19123983.


Integrin binding site within the gC1q domain orchestrates EMILIN-1-induced lymphangiogenesis.

Capuano A, Pivetta E, Baldissera F, Bosisio G, Wassermann B, Bucciotti F, Colombatti A, Sabatelli P, Doliana R, Spessotto P.

Matrix Biol. 2019 Aug;81:34-49. doi: 10.1016/j.matbio.2018.10.006. Epub 2018 Oct 26.


The α4β1/EMILIN1 interaction discloses a novel and unique integrin-ligand type of engagement.

Capuano A, Fogolari F, Bucciotti F, Spessotto P, Nicolosi PA, Mucignat MT, Cervi M, Esposito G, Colombatti A, Doliana R.

Matrix Biol. 2018 Mar;66:50-66. doi: 10.1016/j.matbio.2017.10.001. Epub 2017 Oct 14.


Probe-based confocal laser endomicroscopy for in vivo evaluation of the tumor vasculature in gastric and rectal carcinomas.

Spessotto P, Fornasarig M, Pivetta E, Maiero S, Magris R, Mongiat M, Canzonieri V, De Paoli P, De Paoli A, Buonadonna A, Serraino D, Panato C, Belluco C, Cannizzaro R.

Sci Rep. 2017 Aug 29;7(1):9819. doi: 10.1038/s41598-017-10963-1.


Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells.

Sonego M, Pellizzari I, Dall'Acqua A, Pivetta E, Lorenzon I, Benevol S, Bomben R, Spessotto P, Sorio R, Gattei V, Belletti B, Schiappacassi M, Baldassarre G.

Sci Rep. 2017 Aug 2;7(1):7104. doi: 10.1038/s41598-017-07005-1.


The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis.

Andreuzzi E, Colladel R, Pellicani R, Tarticchio G, Cannizzaro R, Spessotto P, Bussolati B, Brossa A, De Paoli P, Canzonieri V, Iozzo RV, Colombatti A, Mongiat M.

Matrix Biol. 2017 Dec;64:40-53. doi: 10.1016/j.matbio.2017.04.002. Epub 2017 Apr 21.


The extracellular matrix protein EMILIN1 silences the RAS-ERK pathway via α4β1 integrin and decreases tumor cell growth.

Modica TME, Maiorani O, Sartori G, Pivetta E, Doliana R, Capuano A, Colombatti A, Spessotto P.

Oncotarget. 2017 Apr 18;8(16):27034-27046. doi: 10.18632/oncotarget.15067.


Neutrophil elastase cleavage of the gC1q domain impairs the EMILIN1-α4β1 integrin interaction, cell adhesion and anti-proliferative activity.

Maiorani O, Pivetta E, Capuano A, Modica TM, Wassermann B, Bucciotti F, Colombatti A, Doliana R, Spessotto P.

Sci Rep. 2017 Jan 11;7:39974. doi: 10.1038/srep39974.


Local inhibition of elastase reduces EMILIN1 cleavage reactivating lymphatic vessel function in a mouse lymphoedema model.

Pivetta E, Wassermann B, Del Bel Belluz L, Danussi C, Modica TM, Maiorani O, Bosisio G, Boccardo F, Canzonieri V, Colombatti A, Spessotto P.

Clin Sci (Lond). 2016 Jul 1;130(14):1221-36. doi: 10.1042/CS20160064. Epub 2016 Feb 26.


Diagnostic Exome Sequencing Identifies a Novel Gene, EMILIN1, Associated with Autosomal-Dominant Hereditary Connective Tissue Disease.

Capuano A, Bucciotti F, Farwell KD, Tippin Davis B, Mroske C, Hulick PJ, Weissman SM, Gao Q, Spessotto P, Colombatti A, Doliana R.

Hum Mutat. 2016 Jan;37(1):84-97. doi: 10.1002/humu.22920. Epub 2015 Nov 4.


Tumor microenvironment in diffuse large B-cell lymphoma: Matrixmetalloproteinases activation is mediated by osteopontin overexpression.

Malaponte G, Hafsi S, Polesel J, Castellano G, Spessotto P, Guarneri C, Canevari S, Signorelli SS, McCubrey JA, Libra M.

Biochim Biophys Acta. 2016 Mar;1863(3):483-489. doi: 10.1016/j.bbamcr.2015.09.018. Epub 2015 Sep 14.


Functional osteoclastogenesis: the baseline variability in blood donor precursors is not associated with age and gender.

Pivetta E, Wassermann B, Bulian P, Steffan A, Colombatti A, Polesel J, Spessotto P.

Oncotarget. 2015 Oct 13;6(31):31889-900. doi: 10.18632/oncotarget.5575.


Neutrophil elastase-dependent cleavage compromises the tumor suppressor role of EMILIN1.

Pivetta E, Danussi C, Wassermann B, Modica TM, Del Bel Belluz L, Canzonieri V, Colombatti A, Spessotto P.

Matrix Biol. 2014 Feb;34:22-32. doi: 10.1016/j.matbio.2014.01.018. Epub 2014 Feb 7.


EMILIN1/α9β1 integrin interaction is crucial in lymphatic valve formation and maintenance.

Danussi C, Del Bel Belluz L, Pivetta E, Modica TM, Muro A, Wassermann B, Doliana R, Sabatelli P, Colombatti A, Spessotto P.

Mol Cell Biol. 2013 Nov;33(22):4381-94. doi: 10.1128/MCB.00872-13. Epub 2013 Sep 9.


An EMILIN1-negative microenvironment promotes tumor cell proliferation and lymph node invasion.

Danussi C, Petrucco A, Wassermann B, Modica TM, Pivetta E, Del Bel Belluz L, Colombatti A, Spessotto P.

Cancer Prev Res (Phila). 2012 Sep;5(9):1131-43. doi: 10.1158/1940-6207.CAPR-12-0076-T. Epub 2012 Jul 24.


Endomicroscopy and cancer: a new approach to the visualization of neoangiogenesis.

Cannizzaro R, Mongiat M, Canzonieri V, Fornasarig M, Maiero S, De Re V, Todaro F, De Paoli P, Spessotto P.

Gastroenterol Res Pract. 2012;2012:537170. doi: 10.1155/2012/537170. Epub 2012 Jan 12.


MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases.

Pivetta E, Scapolan M, Pecolo M, Wassermann B, Abu-Rumeileh I, Balestreri L, Borsatti E, Tripodo C, Colombatti A, Spessotto P.

Breast Cancer Res. 2011 Oct 27;13(5):R105. doi: 10.1186/bcr3047.


EMILIN1-α4/α9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation.

Danussi C, Petrucco A, Wassermann B, Pivetta E, Modica TM, Del Bel Belluz L, Colombatti A, Spessotto P.

J Cell Biol. 2011 Oct 3;195(1):131-45. doi: 10.1083/jcb.201008013. Epub 2011 Sep 26.


The EMILIN/Multimerin family.

Colombatti A, Spessotto P, Doliana R, Mongiat M, Bressan GM, Esposito G.

Front Immunol. 2012 Jan 6;2:93. doi: 10.3389/fimmu.2011.00093. eCollection 2011.


An alternative role of C1q in cell migration and tissue remodeling: contribution to trophoblast invasion and placental development.

Agostinis C, Bulla R, Tripodo C, Gismondi A, Stabile H, Bossi F, Guarnotta C, Garlanda C, De Seta F, Spessotto P, Santoni A, Ghebrehiwet B, Girardi G, Tedesco F.

J Immunol. 2010 Oct 1;185(7):4420-9. doi: 10.4049/jimmunol.0903215. Epub 2010 Sep 1.


Blood-derived human osteoclast resorption activity is impaired by Hyaluronan-CD44 engagement via a p38-dependent mechanism.

Pivetta E, Scapolan M, Wassermann B, Steffan A, Colombatti A, Spessotto P.

J Cell Physiol. 2011 Mar;226(3):769-79. doi: 10.1002/jcp.22398.


MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment.

Spinola M, Falvella FS, Colombo F, Sullivan JP, Shames DS, Girard L, Spessotto P, Minna JD, Dragani TA.

Mol Cancer. 2010 Mar 17;9:62. doi: 10.1186/1476-4598-9-62.


Role of E2F1-cyclin E1-cyclin E2 circuit in human coronary smooth muscle cell proliferation and therapeutic potential of its downregulation by siRNAs.

Dapas B, Farra R, Grassi M, Giansante C, Fiotti N, Uxa L, Rainaldi G, Mercatanti A, Colombatti A, Spessotto P, Lacovich V, Guarnieri G, Grassi G.

Mol Med. 2009 Sep-Oct;15(9-10):297-306. doi: 10.2119/molmed.2009.00030. Epub 2009 Jun 25.


A newly generated functional antibody identifies Tn antigen as a novel determinant in the cancer cell-lymphatic endothelium interaction.

Danussi C, Coslovi A, Campa C, Mucignat MT, Spessotto P, Uggeri F, Paoletti S, Colombatti A.

Glycobiology. 2009 Oct;19(10):1056-67. doi: 10.1093/glycob/cwp085. Epub 2009 Jun 15.


Fluorescence-based assays for in vitro analysis of cell adhesion and migration.

Spessotto P, Lacrima K, Nicolosi PA, Pivetta E, Scapolan M, Perris R.

Methods Mol Biol. 2009;522:221-50. doi: 10.1007/978-1-59745-413-1_16.


Differential Expression of IRS-1 and IRS-2 in Uterine Leiomyosarcomas with Distinct Oncogenic Phenotypes: Lack of Correlation with Downstream Signaling Events.

Colombatti A, Russo P, Cervi M, Bogetto L, Wassermann B, Mainiero F, Spessotto P.

Sarcoma. 2002;6(3):89-96. doi: 10.1080/1357714021000065387.


The solution structure of EMILIN1 globular C1q domain reveals a disordered insertion necessary for interaction with the alpha4beta1 integrin.

Verdone G, Doliana R, Corazza A, Colebrooke SA, Spessotto P, Bot S, Bucciotti F, Capuano A, Silvestri A, Viglino P, Campbell ID, Colombatti A, Esposito G.

J Biol Chem. 2008 Jul 4;283(27):18947-56. doi: 10.1074/jbc.M801085200. Epub 2008 May 7.


Emilin1 deficiency causes structural and functional defects of lymphatic vasculature.

Danussi C, Spessotto P, Petrucco A, Wassermann B, Sabatelli P, Montesi M, Doliana R, Bressan GM, Colombatti A.

Mol Cell Biol. 2008 Jun;28(12):4026-39. doi: 10.1128/MCB.02062-07. Epub 2008 Apr 14.


Expression profiles in malignant fibrous histiocytomas: clues for differentiating 'spindle cell' and 'pleomorphic' subtypes.

Scapolan M, Perin T, Wassermann B, Canzonieri V, Colombatti A, Italia F, Spessotto P.

Eur J Cancer. 2008 Jan;44(2):298-309. Epub 2007 Dec 4.


Altered expression of urokinase-type plasminogen activator and plasminogen activator inhibitor in high-risk soft tissue sarcomas.

Benassi MS, Ponticelli F, Azzoni E, Gamberi G, Pazzaglia L, Chiechi A, Conti A, Spessotto P, Scapolan M, Pignotti E, Bacchini P, Picci P.

Histol Histopathol. 2007 Sep;22(9):1017-24. doi: 10.14670/HH-22.1017.


Laminin-332 (Laminin-5) is the major motility ligand for B cell chronic lymphocytic leukemia.

Spessotto P, Zucchetto A, Degan M, Wasserman B, Danussi C, Bomben R, Perris R, Canzonieri V, Radillo O, Colombatti A, Gattei V.

Matrix Biol. 2007 Jul;26(6):473-84. Epub 2007 Apr 11.


EMILIN1 represents a major stromal element determining human trophoblast invasion of the uterine wall.

Spessotto P, Bulla R, Danussi C, Radillo O, Cervi M, Monami G, Bossi F, Tedesco F, Doliana R, Colombatti A.

J Cell Sci. 2006 Nov 1;119(Pt 21):4574-84.


Inhibition of B16 melanoma metastases with the ruthenium complex imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate and down-regulation of tumor cell invasion.

Gava B, Zorzet S, Spessotto P, Cocchietto M, Sava G.

J Pharmacol Exp Ther. 2006 Apr;317(1):284-91. Epub 2005 Dec 20.


p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion.

Baldassarre G, Belletti B, Nicoloso MS, Schiappacassi M, Vecchione A, Spessotto P, Morrione A, Canzonieri V, Colombatti A.

Cancer Cell. 2005 Jan;7(1):51-63.


VE-cadherin is a critical molecule for trophoblast-endothelial cell interaction in decidual spiral arteries.

Bulla R, Villa A, Bossi F, Cassetti A, Radillo O, Spessotto P, De Seta F, Guaschino S, Tedesco F.

Exp Cell Res. 2005 Feb 1;303(1):101-13.


Actin-dependent tumour cell adhesion after short-term exposure to the antimetastasis ruthenium complex NAMI-A.

Sava G, Frausin F, Cocchietto M, Vita F, Podda E, Spessotto P, Furlani A, Scarcia V, Zabucchi G.

Eur J Cancer. 2004 Jun;40(9):1383-96.


Preferential locomotion of leukemic cells towards laminin isoforms 8 and 10.

Spessotto P, Gronkowska A, Deutzmann R, Perris R, Colombatti A.

Matrix Biol. 2003 Jun;22(4):351-61.


Role of alpha8 integrin in mesangial cell adhesion, migration, and proliferation.

Bieritz B, Spessotto P, Colombatti A, Jahn A, Prols F, Hartner A.

Kidney Int. 2003 Jul;64(1):119-27.


Vascular PG-M/versican variants promote platelet adhesion at low shear rates and cooperate with collagens to induce aggregation.

Mazzucato M, Cozzi MR, Pradella P, Perissinotto D, Malmstrom A, Morgelin M, Spessotto P, Colombatti A, De Marco L, Perris R.

FASEB J. 2002 Dec;16(14):1903-16.


beta 1 Integrin-dependent cell adhesion to EMILIN-1 is mediated by the gC1q domain.

Spessotto P, Cervi M, Mucignat MT, Mungiguerra G, Sartoretto I, Doliana R, Colombatti A.

J Biol Chem. 2003 Feb 21;278(8):6160-7. Epub 2002 Nov 26.


H(2)O(2) induces translocation of APE/Ref-1 to mitochondria in the Raji B-cell line.

Frossi B, Tell G, Spessotto P, Colombatti A, Vitale G, Pucillo C.

J Cell Physiol. 2002 Nov;193(2):180-6.


Hyaluronan-CD44 interaction hampers migration of osteoclast-like cells by down-regulating MMP-9.

Spessotto P, Rossi FM, Degan M, Di Francia R, Perris R, Colombatti A, Gattei V.

J Cell Biol. 2002 Sep 16;158(6):1133-44. Epub 2002 Sep 16.


Distribution of PG-M/versican variants in human tissues and de novo expression of isoform V3 upon endothelial cell activation, migration, and neoangiogenesis in vitro.

Cattaruzza S, Schiappacassi M, Ljungberg-Rose A, Spessotto P, Perissinotto D, Mörgelin M, Mucignat MT, Colombatti A, Perris R.

J Biol Chem. 2002 Dec 6;277(49):47626-35. Epub 2002 Sep 6.


Improving fluorescence-based assays for the in vitro analysis of cell adhesion and migration.

Spessotto P, Giacomello E, Perri R.

Mol Biotechnol. 2002 Mar;20(3):285-304. Review.


Antigene effect in K562 cells of a PEG-conjugated triplex-forming oligonucleotide targeted to the bcr/abl oncogene.

Rapozzi V, Cogoi S, Spessotto P, Risso A, Bonora GM, Quadrifoglio F, Xodo LE.

Biochemistry. 2002 Jan 15;41(2):502-10.


Laminin isoforms 8 and 10 are primary components of the subendothelial basement membrane promoting interaction with neoplastic lymphocytes.

Spessotto P, Yin Z, Magro G, Deutzmann R, Chiu A, Colombatti A, Perris R.

Cancer Res. 2001 Jan 1;61(1):339-47.

Supplemental Content

Loading ...
Support Center