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Items: 21

1.

Telomeric epigenetic response mediated by Gadd45a regulates stem cell aging and lifespan.

Diao D, Wang H, Li T, Shi Z, Jin X, Sperka T, Zhu X, Zhang M, Yang F, Cong Y, Shen L, Zhan Q, Yan J, Song Z, Ju Z.

EMBO Rep. 2018 Aug 20. pii: e45494. doi: 10.15252/embr.201745494. [Epub ahead of print]

PMID:
30126922
2.

Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage.

Tao S, Tang D, Morita Y, Sperka T, Omrani O, Lechel A, Sakk V, Kraus J, Kestler HA, Kühl M, Rudolph KL.

EMBO J. 2017 Oct 2;36(19):2920-2921. doi: 10.15252/embj.201797813. No abstract available.

3.

VEGFR2 Signaling Prevents Colorectal Cancer Cell Senescence to Promote Tumorigenesis in Mice With Colitis.

Foersch S, Sperka T, Lindner C, Taut A, Rudolph KL, Breier G, Boxberger F, Rau TT, Hartmann A, Stürzl M, Wittkopf N, Haep L, Wirtz S, Neurath MF, Waldner MJ.

Gastroenterology. 2015 Jul;149(1):177-189.e10. doi: 10.1053/j.gastro.2015.03.016. Epub 2015 Mar 19.

PMID:
25797700
4.

Genome instability of ageing stem cells--Induction and defence mechanisms.

Burkhalter MD, Rudolph KL, Sperka T.

Ageing Res Rev. 2015 Sep;23(Pt A):29-36. doi: 10.1016/j.arr.2015.01.004. Epub 2015 Feb 7. Review.

5.

Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage.

Tao S, Tang D, Morita Y, Sperka T, Omrani O, Lechel A, Sakk V, Kraus J, Kestler HA, Kühl M, Rudolph KL.

EMBO J. 2015 Mar 4;34(5):624-40. doi: 10.15252/embj.201490700. Epub 2015 Jan 21. Erratum in: EMBO J. 2017 Oct 2;36(19):2920-2921.

6.

Regulation of Son of sevenless by the membrane-actin linker protein ezrin.

Geissler KJ, Jung MJ, Riecken LB, Sperka T, Cui Y, Schacke S, Merkel U, Markwart R, Rubio I, Than ME, Breithaupt C, Peuker S, Seifert R, Kaupp UB, Herrlich P, Morrison H.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20587-92. doi: 10.1073/pnas.1222078110. Epub 2013 Dec 2.

7.

DNA damage checkpoints in stem cells, ageing and cancer.

Sperka T, Wang J, Rudolph KL.

Nat Rev Mol Cell Biol. 2012 Sep;13(9):579-90. doi: 10.1038/nrm3420. Review.

PMID:
22914294
8.

Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction.

Sperka T, Song Z, Morita Y, Nalapareddy K, Guachalla LM, Lechel A, Begus-Nahrmann Y, Burkhalter MD, Mach M, Schlaudraff F, Liss B, Ju Z, Speicher MR, Rudolph KL.

Nat Cell Biol. 2011 Dec 4;14(1):73-9. doi: 10.1038/ncb2388.

PMID:
22138576
9.

Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.

Sperka T, Geissler KJ, Merkel U, Scholl I, Rubio I, Herrlich P, Morrison HL.

PLoS One. 2011;6(11):e27511. doi: 10.1371/journal.pone.0027511. Epub 2011 Nov 21.

10.

Urokinase down-regulation by aprotinin in rabbit corneal cells after photorefractive keratectomy.

Csutak A, Silver DM, Sperka T, Kádas J, Vereb G, Berta A, Tozsér J.

Curr Eye Res. 2010 Sep;35(9):806-11. doi: 10.3109/02713683.2010.490319.

PMID:
20795862
11.

Regulation of calpain B from Drosophila melanogaster by phosphorylation.

Kovács L, Alexa A, Klement E, Kókai E, Tantos A, Gógl G, Sperka T, Medzihradszky KF, Tözsér J, Dombrádi V, Friedrich P.

FEBS J. 2009 Sep;276(17):4959-72. doi: 10.1111/j.1742-4658.2009.07198.x. Epub 2009 Aug 4.

12.

Properties of an ezrin mutant defective in F-actin binding.

Saleh HS, Merkel U, Geissler KJ, Sperka T, Sechi A, Breithaupt C, Morrison H.

J Mol Biol. 2009 Jan 30;385(4):1015-31. doi: 10.1016/j.jmb.2008.11.051. Epub 2008 Dec 3.

PMID:
19084535
13.

Amino acid preferences of retroviral proteases for amino-terminal positions in a type 1 cleavage site.

Eizert H, Bander P, Bagossi P, Sperka T, Miklóssy G, Boross P, Weber IT, Tözsér J.

J Virol. 2008 Oct;82(20):10111-7. doi: 10.1128/JVI.00418-08. Epub 2008 Aug 13.

14.

Bovine leukemia virus protease: comparison with human T-lymphotropic virus and human immunodeficiency virus proteases.

Sperka T, Miklóssy G, Tie Y, Bagossi P, Zahuczky G, Boross P, Matúz K, Harrison RW, Weber IT, Tözsér J.

J Gen Virol. 2007 Jul;88(Pt 7):2052-63.

PMID:
17554040
15.

Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac.

Morrison H, Sperka T, Manent J, Giovannini M, Ponta H, Herrlich P.

Cancer Res. 2007 Jan 15;67(2):520-7.

16.

Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase.

Jin H, Sperka T, Herrlich P, Morrison H.

Nature. 2006 Aug 3;442(7102):576-9.

PMID:
16885985
17.

Effect of mutations on the dimer stability and the pH optimum of the human foamy virus protease.

Sperka T, Boross P, Eizert H, Tözsér J, Bagossi P.

Protein Eng Des Sel. 2006 Aug;19(8):369-75. Epub 2006 Jun 24.

PMID:
16799151
18.

Characterization of the murine leukemia virus protease and its comparison with the human immunodeficiency virus type 1 protease.

Fehér A, Boross P, Sperka T, Miklóssy G, Kádas J, Bagossi P, Oroszlan S, Weber IT, Tözsér J.

J Gen Virol. 2006 May;87(Pt 5):1321-30.

PMID:
16603535
19.

Beta-lactam compounds as apparently uncompetitive inhibitors of HIV-1 protease.

Sperka T, Pitlik J, Bagossi P, Tözsér J.

Bioorg Med Chem Lett. 2005 Jun 15;15(12):3086-90.

PMID:
15893929
20.

Amino acid preferences for a critical substrate binding subsite of retroviral proteases in type 1 cleavage sites.

Bagossi P, Sperka T, Fehér A, Kádas J, Zahuczky G, Miklóssy G, Boross P, Tözsér J.

J Virol. 2005 Apr;79(7):4213-8.

21.

Expression of the murine leukemia virus protease in fusion with maltose-binding protein in Escherichia coli.

Fehér A, Boross P, Sperka T, Oroszlan S, Tözsér J.

Protein Expr Purif. 2004 May;35(1):62-8.

PMID:
15039067

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