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Items: 5


Quantification of ligand density and stoichiometry on the surface of liposomes using single-molecule fluorescence imaging.

Belfiore L, Spenkelink LM, Ranson M, van Oijen AM, Vine KL.

J Control Release. 2018 May 28;278:80-86. doi: 10.1016/j.jconrel.2018.03.022. Epub 2018 Mar 22.


Single-molecule visualization of Saccharomyces cerevisiae leading-strand synthesis reveals dynamic interaction between MTC and the replisome.

Lewis JS, Spenkelink LM, Schauer GD, Hill FR, Georgescu RE, O'Donnell ME, van Oijen AM.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10630-10635. doi: 10.1073/pnas.1711291114. Epub 2017 Sep 18.


Single-molecule visualization of fast polymerase turnover in the bacterial replisome.

Lewis JS, Spenkelink LM, Jergic S, Wood EA, Monachino E, Horan NP, Duderstadt KE, Cox MM, Robinson A, Dixon NE, van Oijen AM.

Elife. 2017 Apr 22;6. pii: e23932. doi: 10.7554/eLife.23932.


Watching cellular machinery in action, one molecule at a time.

Monachino E, Spenkelink LM, van Oijen AM.

J Cell Biol. 2017 Jan 2;216(1):41-51. doi: 10.1083/jcb.201610025. Epub 2016 Dec 15. Review.


Single-molecule imaging at high fluorophore concentrations by local activation of dye.

Geertsema HJ, Schulte AC, Spenkelink LM, McGrath WJ, Morrone SR, Sohn J, Mangel WF, Robinson A, van Oijen AM.

Biophys J. 2015 Feb 17;108(4):949-956. doi: 10.1016/j.bpj.2014.12.019.

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