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Items: 1 to 50 of 521

1.

PRCD Is a Small Disc-Specific Rhodopsin-Binding Protein of Unknown Function.

Spencer WJ, Arshavsky VY.

Adv Exp Med Biol. 2019;1185:531-535. doi: 10.1007/978-3-030-27378-1_87.

PMID:
31884666
2.

Risk variables associated with abnormal calcium, magnesium and phosphate levels among emergency department patients.

Taylor DM, Date PA, Ugoni A, Smith JL, Spencer WS, de Tonnerre EJ, Yeoh MJ.

Emerg Med Australas. 2019 Dec 17. doi: 10.1111/1742-6723.13411. [Epub ahead of print]

PMID:
31847050
3.

Photoreceptor disc membranes are formed through an Arp2/3-dependent lamellipodium-like mechanism.

Spencer WJ, Lewis TR, Phan S, Cady MA, Serebrovskaya EO, Schneider NF, Kim KY, Cameron LA, Skiba NP, Ellisman MH, Arshavsky VY.

Proc Natl Acad Sci U S A. 2019 Dec 16. pii: 201913518. doi: 10.1073/pnas.1913518117. [Epub ahead of print]

PMID:
31843915
4.

Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial.

Fowler AA 3rd, Truwit JD, Hite RD, Morris PE, DeWilde C, Priday A, Fisher B, Thacker LR 2nd, Natarajan R, Brophy DF, Sculthorpe R, Nanchal R, Syed A, Sturgill J, Martin GS, Sevransky J, Kashiouris M, Hamman S, Egan KF, Hastings A, Spencer W, Tench S, Mehkri O, Bindas J, Duggal A, Graf J, Zellner S, Yanny L, McPolin C, Hollrith T, Kramer D, Ojielo C, Damm T, Cassity E, Wieliczko A, Halquist M.

JAMA. 2019 Oct 1;322(13):1261-1270. doi: 10.1001/jama.2019.11825.

PMID:
31573637
5.

Determination of the best early warning scores to predict clinical outcomes of patients in the emergency department.

Spencer W, Smith J, Date P, de Tonnerre E, Taylor DM.

Emerg Med J. 2019 Dec;36(12):716-721. doi: 10.1136/emermed-2019-208622. Epub 2019 Jul 31.

PMID:
31366627
6.

Lmx1b is required at multiple stages to build expansive serotonergic axon architectures.

Donovan LJ, Spencer WC, Kitt MM, Eastman BA, Lobur KJ, Jiao K, Silver J, Deneris ES.

Elife. 2019 Jul 29;8. pii: e48788. doi: 10.7554/eLife.48788.

7.

PRCD is essential for high-fidelity photoreceptor disc formation.

Spencer WJ, Ding JD, Lewis TR, Yu C, Phan S, Pearring JN, Kim KY, Thor A, Mathew R, Kalnitsky J, Hao Y, Travis AM, Biswas SK, Lo WK, Besharse JC, Ellisman MH, Saban DR, Burns ME, Arshavsky VY.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):13087-13096. doi: 10.1073/pnas.1906421116. Epub 2019 Jun 12.

8.

Utility of calcium, magnesium and phosphate testing in the emergency department.

Date PA, Smith JL, Spencer WS, de Tonnerre EJ, Yeoh MJ, Taylor DM.

Emerg Med Australas. 2019 Jun 2. doi: 10.1111/1742-6723.13332. [Epub ahead of print]

PMID:
31155837
9.

Guidance for the decontamination of intracavity medical devices: the report of a working group of the Healthcare Infection Society.

Bradley CR, Hoffman PN, Egan K, Jacobson SK, Colville A, Spencer W, Larkin S, Jenks PJ.

J Hosp Infect. 2019 Jan;101(1):1-10. doi: 10.1016/j.jhin.2018.08.003. Epub 2018 Aug 7.

PMID:
30092292
10.

Transducin β-Subunit Can Interact with Multiple G-Protein γ-Subunits to Enable Light Detection by Rod Photoreceptors.

Dexter PM, Lobanova ES, Finkelstein S, Spencer WJ, Skiba NP, Arshavsky VY.

eNeuro. 2018 Jun 11;5(3). pii: ENEURO.0144-18.2018. doi: 10.1523/ENEURO.0144-18.2018. eCollection 2018 May-Jun.

11.

Case Report of Proliferative Peripheral Retinopathy in Two Familial Lissencephaly Infants with Miller-Dieker Syndrome.

Shoukfeh O, Richards AB, Prouty LA, Hinrichsen J, Spencer WR, Langford MP.

J Pediatr Genet. 2018 Jun;7(2):86-91. doi: 10.1055/s-0037-1612638. Epub 2017 Dec 29.

12.

Development of a goat model for evaluation of withaferin A: Cervical implants for the treatment of cervical intraepithelial neoplasia.

Sherwood LC, Aqil F, Vadhanam MV, Jeyabalan J, Munagala R, Hoetker D, Srivastava S, Singh IP, Cambron S, O'Toole M, Spencer W, Parker LP, Gupta RC.

Exp Mol Pathol. 2017 Dec;103(3):320-329. doi: 10.1016/j.yexmp.2017.11.008. Epub 2017 Nov 21.

13.

The Atypical MAP Kinase SWIP-13/ERK8 Regulates Dopamine Transporters through a Rho-Dependent Mechanism.

Bermingham DP, Hardaway JA, Refai O, Marks CR, Snider SL, Sturgeon SM, Spencer WC, Colbran RJ, Miller DM 3rd, Blakely RD.

J Neurosci. 2017 Sep 20;37(38):9288-9304. doi: 10.1523/JNEUROSCI.1582-17.2017. Epub 2017 Aug 21.

14.

Regulatory Mechanisms Controlling Maturation of Serotonin Neuron Identity and Function.

Spencer WC, Deneris ES.

Front Cell Neurosci. 2017 Jul 19;11:215. doi: 10.3389/fncel.2017.00215. eCollection 2017.

15.

Corrigendum to 'Demographic and clinical characteristics of type 2 diabetes mellitus patients initiating dipeptidyl peptidase-4 inhibitors - a retrospective study of UK general practice'.

Tebboth A, Lee S, Scowcroft A, Bingham-Gardiner P, Spencer W, Bolodeoku J, Hassan SW.

Clin Ther. 2017 Jun;39(6):1266-1270. doi: 10.1016/j.clinthera.2017.05.002. Epub 2017 May 15. No abstract available.

16.

Photoreceptor discs form through peripherin-dependent suppression of ciliary ectosome release.

Salinas RY, Pearring JN, Ding JD, Spencer WJ, Hao Y, Arshavsky VY.

J Cell Biol. 2017 May 1;216(5):1489-1499. doi: 10.1083/jcb.201608081. Epub 2017 Apr 5.

17.

Milk-derived exosomes for oral delivery of paclitaxel.

Agrawal AK, Aqil F, Jeyabalan J, Spencer WA, Beck J, Gachuki BW, Alhakeem SS, Oben K, Munagala R, Bondada S, Gupta RC.

Nanomedicine. 2017 Jul;13(5):1627-1636. doi: 10.1016/j.nano.2017.03.001. Epub 2017 Mar 11.

PMID:
28300659
18.

Corrigendum to 'Demographic and Clinical Characteristics of Type 2 Diabetes Mellitus Patients Initiating Dipeptidyl Peptidase-4 Inhibitors - A Retrospective Study of UK General Practice' Clin Ther 2016;8:1825-1832.e15.

Tebboth A, Lee S, Scowcroft A, Bingham-Gardiner P, Spencer W, Bolodeoku J, Hassan SW.

Clin Ther. 2017 Mar;39(3):662-662.e15. doi: 10.1016/j.clinthera.2017.01.026. Epub 2017 Feb 8. No abstract available.

19.

Availability of endovascular therapies for cerebrovascular disease at primary stroke centers.

Alberts MJ, Range J, Spencer W, Cantwell V, Hampel MJ.

Interv Neuroradiol. 2017 Feb;23(1):64-68. doi: 10.1177/1591019916678199. Epub 2016 Nov 30.

20.

Progressive Rod-Cone Degeneration (PRCD) Protein Requires N-Terminal S-Acylation and Rhodopsin Binding for Photoreceptor Outer Segment Localization and Maintaining Intracellular Stability.

Spencer WJ, Pearring JN, Salinas RY, Loiselle DR, Skiba NP, Arshavsky VY.

Biochemistry. 2016 Sep 13;55(36):5028-37. doi: 10.1021/acs.biochem.6b00489. Epub 2016 Aug 30.

21.

Demographic and Clinical Characteristics of Patients With Type 2 Diabetes Mellitus Initiating Dipeptidyl Peptidase 4 Inhibitors: A Retrospective Study of UK General Practice.

Tebboth A, Lee S, Scowcroft A, Bingham-Gardiner P, Spencer W, Bolodeoku J, Hassan SW.

Clin Ther. 2016 Aug;38(8):1825-1832.e15. doi: 10.1016/j.clinthera.2016.07.006. Epub 2016 Aug 2. Erratum in: Clin Ther. 2017 Mar;39(3):662-662.e15. Clin Ther. 2017 Jun;39(6):1266-1270.

22.

Localized aggressive periodontitis immune response to healthy and diseased subgingival plaque.

Shaddox LM, Spencer WP, Velsko IM, Al-Kassab H, Huang H, Calderon N, Aukhil I, Wallet SM.

J Clin Periodontol. 2016 Sep;43(9):746-53. doi: 10.1111/jcpe.12560. Epub 2016 Jul 15.

23.

Injuries Reported and Recorded for Adults with Intellectual Disabilities Who Live with Paid Support in Scotland: a Comparison with Scottish Adults in the General Population.

Petropoulou E, Finlayson J, Hay M, Spencer W, Park R, Tannock H, Galbraith E, Godwin J, Skelton DA.

J Appl Res Intellect Disabil. 2017 Mar;30(2):408-415. doi: 10.1111/jar.12244. Epub 2016 Feb 10.

PMID:
26864714
24.

Pet-1 Switches Transcriptional Targets Postnatally to Regulate Maturation of Serotonin Neuron Excitability.

Wyler SC, Spencer WC, Green NH, Rood BD, Crawford L, Craige C, Gresch P, McMahon DG, Beck SG, Deneris E.

J Neurosci. 2016 Feb 3;36(5):1758-74. doi: 10.1523/JNEUROSCI.3798-15.2016.

25.

Guanylate cyclase 1 relies on rhodopsin for intracellular stability and ciliary trafficking.

Pearring JN, Spencer WJ, Lieu EC, Arshavsky VY.

Elife. 2015 Nov 21;4. pii: e12058. doi: 10.7554/eLife.12058.

26.

Glial Expression of the Caenorhabditis elegans Gene swip-10 Supports Glutamate Dependent Control of Extrasynaptic Dopamine Signaling.

Hardaway JA, Sturgeon SM, Snarrenberg CL, Li Z, Xu XZ, Bermingham DP, Odiase P, Spencer WC, Miller DM 3rd, Carvelli L, Hardie SL, Blakely RD.

J Neurosci. 2015 Jun 24;35(25):9409-23. doi: 10.1523/JNEUROSCI.0800-15.2015.

27.

Isolation of specific neurons from C. elegans larvae for gene expression profiling.

Spencer WC, McWhirter R, Miller T, Strasbourger P, Thompson O, Hillier LW, Waterston RH, Miller DM 3rd.

PLoS One. 2014 Nov 5;9(11):e112102. doi: 10.1371/journal.pone.0112102. eCollection 2014.

28.

Comparative analysis of the transcriptome across distant species.

Gerstein MB, Rozowsky J, Yan KK, Wang D, Cheng C, Brown JB, Davis CA, Hillier L, Sisu C, Li JJ, Pei B, Harmanci AO, Duff MO, Djebali S, Alexander RP, Alver BH, Auerbach R, Bell K, Bickel PJ, Boeck ME, Boley NP, Booth BW, Cherbas L, Cherbas P, Di C, Dobin A, Drenkow J, Ewing B, Fang G, Fastuca M, Feingold EA, Frankish A, Gao G, Good PJ, Guigó R, Hammonds A, Harrow J, Hoskins RA, Howald C, Hu L, Huang H, Hubbard TJ, Huynh C, Jha S, Kasper D, Kato M, Kaufman TC, Kitchen RR, Ladewig E, Lagarde J, Lai E, Leng J, Lu Z, MacCoss M, May G, McWhirter R, Merrihew G, Miller DM, Mortazavi A, Murad R, Oliver B, Olson S, Park PJ, Pazin MJ, Perrimon N, Pervouchine D, Reinke V, Reymond A, Robinson G, Samsonova A, Saunders GI, Schlesinger F, Sethi A, Slack FJ, Spencer WC, Stoiber MH, Strasbourger P, Tanzer A, Thompson OA, Wan KH, Wang G, Wang H, Watkins KL, Wen J, Wen K, Xue C, Yang L, Yip K, Zaleski C, Zhang Y, Zheng H, Brenner SE, Graveley BR, Celniker SE, Gingeras TR, Waterston R.

Nature. 2014 Aug 28;512(7515):445-8. doi: 10.1038/nature13424.

29.

Beyond the Divinyl Ketone: Innovations in the Generation and Nazarov Cyclization of Pentadienyl Cation Intermediates.

Spencer WT 3rd, Vaidya T, Frontier AJ.

European J Org Chem. 2013 Jun 1;2013(18). doi: 10.1002/ejoc.201300134.

30.

Ingested soluble CD14 from milk is transferred intact into the blood of newborn rats.

Ward TL, Spencer WJ, Davis LD, Harrold J, Mack DR, Altosaar I.

Pediatr Res. 2014 Feb;75(2):252-8. doi: 10.1038/pr.2013.225. Epub 2013 Nov 14.

31.

Sensory neuron fates are distinguished by a transcriptional switch that regulates dendrite branch stabilization.

Smith CJ, O'Brien T, Chatzigeorgiou M, Spencer WC, Feingold-Link E, Husson SJ, Hori S, Mitani S, Gottschalk A, Schafer WR, Miller DM 3rd.

Neuron. 2013 Jul 24;79(2):266-80. doi: 10.1016/j.neuron.2013.05.009.

32.

Proteomic identification of unique photoreceptor disc components reveals the presence of PRCD, a protein linked to retinal degeneration.

Skiba NP, Spencer WJ, Salinas RY, Lieu EC, Thompson JW, Arshavsky VY.

J Proteome Res. 2013 Jun 7;12(6):3010-8. doi: 10.1021/pr4003678. Epub 2013 May 24.

33.

Can the sector afford not to comply?

Prendergast J, Spencer W.

Health Estate. 2012 Nov;66(10):43-8.

PMID:
23193924
34.

Cycloaromatization protocol for synthesis of polysubstituted phenol derivatives: method development and mechanistic studies.

Spencer WT 3rd, Frontier AJ.

J Org Chem. 2012 Sep 7;77(17):7730-6. doi: 10.1021/jo3010952. Epub 2012 Aug 14.

35.

Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors.

Husson SJ, Costa WS, Wabnig S, Stirman JN, Watson JD, Spencer WC, Akerboom J, Looger LL, Treinin M, Miller DM 3rd, Lu H, Gottschalk A.

Curr Biol. 2012 May 8;22(9):743-52. doi: 10.1016/j.cub.2012.02.066. Epub 2012 Apr 5.

36.

Total synthesis of (±)-rocaglamide via oxidation-initiated Nazarov cyclization.

Malona JA, Cariou K, Spencer WT 3rd, Frontier AJ.

J Org Chem. 2012 Feb 17;77(4):1891-908. doi: 10.1021/jo202366c. Epub 2012 Jan 26.

37.

Isolation of functional cardiac immune cells.

McLarty JL, Meléndez GC, Spencer WJ, Levick SP, Brower GL, Janicki JS.

J Vis Exp. 2011 Dec 5;(58). pii: 3020. doi: 10.3791/3020.

38.

Oxidative DNA damage following microsome/Cu(II)-mediated activation of the estrogens, 17β-estradiol, equilenin, and equilin: role of reactive oxygen species.

Spencer WA, Vadhanam MV, Jeyabalan J, Gupta RC.

Chem Res Toxicol. 2012 Feb 20;25(2):305-14. doi: 10.1021/tx200356v. Epub 2012 Jan 6.

PMID:
22126130
39.

Alcohol septal ablation for the treatment of hypertrophic obstructive cardiomyopathy. A multicenter North American registry.

Nagueh SF, Groves BM, Schwartz L, Smith KM, Wang A, Bach RG, Nielsen C, Leya F, Buergler JM, Rowe SK, Woo A, Maldonado YM, Spencer WH 3rd.

J Am Coll Cardiol. 2011 Nov 22;58(22):2322-8. doi: 10.1016/j.jacc.2011.06.073.

40.

Maternal separation and gastrointestinal transit time in neonate rats.

Davis LD, Spencer WJ, Mack DR, Altosaar I.

Lab Anim. 2011 Oct;45(4):280-2. doi: 10.1258/la.2011.010167. Epub 2011 Aug 9.

PMID:
21828078
41.

Toward best practices for developing regional connectivity maps.

Beier P, Spencer W, Baldwin RF, McRae BH.

Conserv Biol. 2011 Oct;25(5):879-92. doi: 10.1111/j.1523-1739.2011.01716.x. Epub 2011 Jul 28. Review.

PMID:
21797924
42.

Sustained systemic delivery of green tea polyphenols by polymeric implants significantly diminishes benzo[a]pyrene-induced DNA adducts.

Cao P, Vadhanam MV, Spencer WA, Cai J, Gupta RC.

Chem Res Toxicol. 2011 Jun 20;24(6):877-86. doi: 10.1021/tx2000625. Epub 2011 May 31.

43.

Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project.

Gerstein MB, Lu ZJ, Van Nostrand EL, Cheng C, Arshinoff BI, Liu T, Yip KY, Robilotto R, Rechtsteiner A, Ikegami K, Alves P, Chateigner A, Perry M, Morris M, Auerbach RK, Feng X, Leng J, Vielle A, Niu W, Rhrissorrakrai K, Agarwal A, Alexander RP, Barber G, Brdlik CM, Brennan J, Brouillet JJ, Carr A, Cheung MS, Clawson H, Contrino S, Dannenberg LO, Dernburg AF, Desai A, Dick L, Dosé AC, Du J, Egelhofer T, Ercan S, Euskirchen G, Ewing B, Feingold EA, Gassmann R, Good PJ, Green P, Gullier F, Gutwein M, Guyer MS, Habegger L, Han T, Henikoff JG, Henz SR, Hinrichs A, Holster H, Hyman T, Iniguez AL, Janette J, Jensen M, Kato M, Kent WJ, Kephart E, Khivansara V, Khurana E, Kim JK, Kolasinska-Zwierz P, Lai EC, Latorre I, Leahey A, Lewis S, Lloyd P, Lochovsky L, Lowdon RF, Lubling Y, Lyne R, MacCoss M, Mackowiak SD, Mangone M, McKay S, Mecenas D, Merrihew G, Miller DM 3rd, Muroyama A, Murray JI, Ooi SL, Pham H, Phippen T, Preston EA, Rajewsky N, Rätsch G, Rosenbaum H, Rozowsky J, Rutherford K, Ruzanov P, Sarov M, Sasidharan R, Sboner A, Scheid P, Segal E, Shin H, Shou C, Slack FJ, Slightam C, Smith R, Spencer WC, Stinson EO, Taing S, Takasaki T, Vafeados D, Voronina K, Wang G, Washington NL, Whittle CM, Wu B, Yan KK, Zeller G, Zha Z, Zhong M, Zhou X; modENCODE Consortium, Ahringer J, Strome S, Gunsalus KC, Micklem G, Liu XS, Reinke V, Kim SK, Hillier LW, Henikoff S, Piano F, Snyder M, Stein L, Lieb JD, Waterston RH.

Science. 2010 Dec 24;330(6012):1775-87. doi: 10.1126/science.1196914. Epub 2010 Dec 22. Erratum in: Science. 2011 Jan 7;331(6013):30.

44.

A spatial and temporal map of C. elegans gene expression.

Spencer WC, Zeller G, Watson JD, Henz SR, Watkins KL, McWhirter RD, Petersen S, Sreedharan VT, Widmer C, Jo J, Reinke V, Petrella L, Strome S, Von Stetina SE, Katz M, Shaham S, Rätsch G, Miller DM 3rd.

Genome Res. 2011 Feb;21(2):325-41. doi: 10.1101/gr.114595.110. Epub 2010 Dec 22.

45.

Receptor-type guanylate cyclase is required for carbon dioxide sensation by Caenorhabditis elegans.

Hallem EA, Spencer WC, McWhirter RD, Zeller G, Henz SR, Rätsch G, Miller DM 3rd, Horvitz HR, Sternberg PW, Ringstad N.

Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):254-9. doi: 10.1073/pnas.1017354108. Epub 2010 Dec 20.

46.

Oxidation-initiated Nazarov cyclization of vinyl alkoxyallenes.

Spencer WT 3rd, Levin MD, Frontier AJ.

Org Lett. 2011 Feb 4;13(3):414-7. doi: 10.1021/ol1027255. Epub 2010 Dec 14.

47.

(14)C radiolabeling of proteins to monitor biodistribution of ingested proteins.

Davis LD, Spencer WJ, Pham VT, Ward TL, Blais DR, Mack DR, Kaplan H, Altosaar I.

Anal Biochem. 2011 Mar 1;410(1):57-61. doi: 10.1016/j.ab.2010.11.028. Epub 2010 Nov 20.

PMID:
21094630
48.

Defibrillation thresholds in hypertrophic cardiomyopathy.

Quin EM, Cuoco FA, Forcina MS, Coker JB, Yoe RH, Spencer WH 3rd, Fernandes VL, Nielsen CD, Sturdivant JL, Leman RB, Wharton JM, Gold MR.

J Cardiovasc Electrophysiol. 2011 May;22(5):569-72. doi: 10.1111/j.1540-8167.2010.01943.x. Epub 2010 Nov 23.

PMID:
21091965
49.

Oxidatively generated DNA damage after Cu(II) catalysis of dopamine and related catecholamine neurotransmitters and neurotoxins: Role of reactive oxygen species.

Spencer WA, Jeyabalan J, Kichambre S, Gupta RC.

Free Radic Biol Med. 2011 Jan 1;50(1):139-47. doi: 10.1016/j.freeradbiomed.2010.10.693. Epub 2010 Nov 12.

50.

Congenital ectopic cilia of the upper eyelid.

Chappell MC, Spencer W, Day SH, Silkiss RZ.

Ophthalmic Plast Reconstr Surg. 2011 Mar-Apr;27(2):e42-4. doi: 10.1097/IOP.0b013e3181e17501.

PMID:
20736868

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