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Items: 1 to 50 of 87

1.

Fingerstick test quantifying humoral and cellular biomarkers indicative for M. leprae infection.

Corstjens PLAM, van Hooij A, Tjon Kon Fat EM, Alam K, Vrolijk LB, Dlamini S, da Silva MB, Spencer JS, Salgado CG, Richardus JH, van Hees CLM, Geluk A.

Clin Biochem. 2019 Apr;66:76-82. doi: 10.1016/j.clinbiochem.2019.01.007. Epub 2019 Jan 26.

2.

The HANDE-QMC Project: Open-Source Stochastic Quantum Chemistry from the Ground State Up.

Spencer JS, Blunt NS, Choi S, Etrych J, Filip MA, Foulkes WMC, Franklin RST, Handley WJ, Malone FD, Neufeld VA, Di Remigio R, Rogers TW, Scott CJC, Shepherd JJ, Vigor WA, Weston J, Xu R, Thom AJW.

J Chem Theory Comput. 2019 Mar 12;15(3):1728-1742. doi: 10.1021/acs.jctc.8b01217. Epub 2019 Feb 18.

PMID:
30681844
3.

The effects of prednisolone treatment on serological responses and lipid profiles in Ethiopian leprosy patients with Erythema Nodosum Leprosum reactions.

Negera E, Tilahun M, Bobosha K, Lambert SM, Walker SL, Spencer JS, Aseffa A, Dockrell HM, Lockwood DN.

PLoS Negl Trop Dis. 2018 Dec 28;12(12):e0007035. doi: 10.1371/journal.pntd.0007035. eCollection 2018 Dec.

4.

Evaluation of Immunodiagnostic Tests for Leprosy in Brazil, China and Ethiopia.

van Hooij A, Tjon Kon Fat EM, Batista da Silva M, Carvalho Bouth R, Cunha Messias AC, Gobbo AR, Lema T, Bobosha K, Li J, Weng X, Salgado CG, Spencer JS, Corstjens PLAM, Geluk A.

Sci Rep. 2018 Dec 18;8(1):17920. doi: 10.1038/s41598-018-36323-1.

5.

Large scale parallelization in stochastic coupled cluster.

Spencer JS, Neufeld VA, Vigor WA, Franklin RST, Thom AJW.

J Chem Phys. 2018 Nov 28;149(20):204103. doi: 10.1063/1.5047420.

PMID:
30501245
6.

Detection of lipoarabinomannan in urine and serum of HIV-positive and HIV-negative TB suspects using an improved capture-enzyme linked immuno absorbent assay and gas chromatography/mass spectrometry.

Amin AG, De P, Spencer JS, Brennan PJ, Daum J, Andre BG, Joe M, Bai Y, Laurentius L, Porter MD, Honnen WJ, Choudhary A, Lowary TL, Pinter A, Chatterjee D.

Tuberculosis (Edinb). 2018 Jul;111:178-187. doi: 10.1016/j.tube.2018.06.004. Epub 2018 Jun 6.

PMID:
30029905
7.

Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos.

da Silva MB, Portela JM, Li W, Jackson M, Gonzalez-Juarrero M, Hidalgo AS, Belisle JT, Bouth RC, Gobbo AR, Barreto JG, Minervino AHH, Cole ST, Avanzi C, Busso P, Frade MAC, Geluk A, Salgado CG, Spencer JS.

PLoS Negl Trop Dis. 2018 Jun 28;12(6):e0006532. doi: 10.1371/journal.pntd.0006532. eCollection 2018 Jun.

8.

Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid of Mycobacterium tuberculosis, and Complexity of Antibody Specificities toward This Antigen.

Choudhary A, Patel D, Honnen W, Lai Z, Prattipati RS, Zheng RB, Hsueh YC, Gennaro ML, Lardizabal A, Restrepo BI, Garcia-Viveros M, Joe M, Bai Y, Shen K, Sahloul K, Spencer JS, Chatterjee D, Broger T, Lowary TL, Pinter A.

J Immunol. 2018 May 1;200(9):3053-3066. doi: 10.4049/jimmunol.1701673. Epub 2018 Apr 2.

9.

miRNome Expression Analysis Reveals New Players on Leprosy Immune Physiopathology.

Salgado CG, Pinto P, Bouth RC, Gobbo AR, Messias ACC, Sandoval TV, Dos Santos AMR, Moreira FC, Vidal AF, Goulart LR, Barreto JG, da Silva MB, Frade MAC, Spencer JS, Santos S, Ribeiro-Dos-Santos Â.

Front Immunol. 2018 Mar 9;9:463. doi: 10.3389/fimmu.2018.00463. eCollection 2018.

10.

Are leprosy case numbers reliable?

Salgado CG, Barreto JG, da Silva MB, Goulart IMB, Barreto JA, de Medeiros Junior NF, Nery JA, Frade MAC, Spencer JS.

Lancet Infect Dis. 2018 Feb;18(2):135-137. doi: 10.1016/S1473-3099(18)30012-4. No abstract available.

PMID:
29412953
11.

Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae.

Benjak A, Avanzi C, Singh P, Loiseau C, Girma S, Busso P, Fontes ANB, Miyamoto Y, Namisato M, Bobosha K, Salgado CG, da Silva MB, Bouth RC, Frade MAC, Filho FB, Barreto JG, Nery JAC, Bührer-Sékula S, Lupien A, Al-Samie AR, Al-Qubati Y, Alkubati AS, Bretzel G, Vera-Cabrera L, Sakho F, Johnson CR, Kodio M, Fomba A, Sow SO, Gado M, Konaté O, Stefani MMA, Penna GO, Suffys PN, Sarno EN, Moraes MO, Rosa PS, Baptista IMFD, Spencer JS, Aseffa A, Matsuoka M, Kai M, Cole ST.

Nat Commun. 2018 Jan 24;9(1):352. doi: 10.1038/s41467-017-02576-z.

12.

Evidence of hidden leprosy in a supposedly low endemic area of Brazil.

Bernardes F Filho, Paula NA, Leite MN, Abi-Rached TLC, Vernal S, Silva MBD, Barreto JG, Spencer JS, Frade MAC.

Mem Inst Oswaldo Cruz. 2017 Dec;112(12):822-828. doi: 10.1590/0074-02760170173.

13.

Immunization against full-length protein and peptides from the Lutzomyia longipalpis sand fly salivary component maxadilan protects against Leishmania major infection in a murine model.

Wheat WH, Arthun EN, Spencer JS, Regan DP, Titus RG, Dow SW.

Vaccine. 2017 Dec 4;35(48 Pt B):6611-6619. doi: 10.1016/j.vaccine.2017.10.039. Epub 2017 Oct 24.

14.

Field-friendly serological tests for determination of M. leprae-specific antibodies.

van Hooij A, Tjon Kon Fat EM, van den Eeden SJF, Wilson L, Batista da Silva M, Salgado CG, Spencer JS, Corstjens PLAM, Geluk A.

Sci Rep. 2017 Aug 21;7(1):8868. doi: 10.1038/s41598-017-07803-7.

15.

Leprosy in Children.

Barreto JG, Frade MAC, Bernardes Filho F, da Silva MB, Spencer JS, Salgado CG.

Curr Infect Dis Rep. 2017 Jun;19(6):23. doi: 10.1007/s11908-017-0577-6. Review.

PMID:
28444521
16.

Unexpectedly high leprosy seroprevalence detected using a random surveillance strategy in midwestern Brazil: A comparison of ELISA and a rapid diagnostic test.

Frade MA, de Paula NA, Gomes CM, Vernal S, Bernardes Filho F, Lugão HB, de Abreu MM, Botini P, Duthie MS, Spencer JS, Soares RC, Foss NT.

PLoS Negl Trop Dis. 2017 Feb 23;11(2):e0005375. doi: 10.1371/journal.pntd.0005375. eCollection 2017 Feb.

17.

Importance of specimen pretreatment for the low-level detection of mycobacterial lipoarabinomannan in human serum.

Laurentius LB, Crawford AC, Mulvihill TS, Granger JH, Robinson R, Spencer JS, Chatterjee D, Hanson KE, Porter MD.

Analyst. 2016 Dec 19;142(1):177-185.

PMID:
27934985
18.

Detection of the tuberculosis antigenic marker mannose-capped lipoarabinomannan in pretreated serum by surface-enhanced Raman scattering.

Crawford AC, Laurentius LB, Mulvihill TS, Granger JH, Spencer JS, Chatterjee D, Hanson KE, Porter MD.

Analyst. 2016 Dec 19;142(1):186-196.

PMID:
27924983
19.

Accurate Exchange-Correlation Energies for the Warm Dense Electron Gas.

Malone FD, Blunt NS, Brown EW, Lee DK, Spencer JS, Foulkes WM, Shepherd JJ.

Phys Rev Lett. 2016 Sep 9;117(11):115701. doi: 10.1103/PhysRevLett.117.115701. Epub 2016 Sep 7.

20.

Diguanylate cyclase activity of the Mycobacterium leprae T cell antigen ML1419c.

Rotcheewaphan S, Belisle JT, Webb KJ, Kim HJ, Spencer JS, Borlee BR.

Microbiology. 2016 Sep;162(9):1651-1661. doi: 10.1099/mic.0.000339. Epub 2016 Jul 22.

21.

What do we actually know about leprosy worldwide?

Salgado CG, Barreto JG, da Silva MB, Frade MAC, Spencer JS.

Lancet Infect Dis. 2016 Jul;16(7):778. doi: 10.1016/S1473-3099(16)30090-1. No abstract available.

PMID:
27352757
22.

Boosting BCG-primed responses with a subunit Apa vaccine during the waning phase improves immunity and imparts protection against Mycobacterium tuberculosis.

Nandakumar S, Kannanganat S, Dobos KM, Lucas M, Spencer JS, Amara RR, Plikaytis BB, Posey JE, Sable SB.

Sci Rep. 2016 May 13;6:25837. doi: 10.1038/srep25837.

23.

Understanding and improving the efficiency of full configuration interaction quantum Monte Carlo.

Vigor WA, Spencer JS, Bearpark MJ, Thom AJ.

J Chem Phys. 2016 Mar 7;144(9):094110. doi: 10.1063/1.4943113.

PMID:
26957160
24.

Developments in stochastic coupled cluster theory: The initiator approximation and application to the uniform electron gas.

Spencer JS, Thom AJ.

J Chem Phys. 2016 Feb 28;144(8):084108. doi: 10.1063/1.4942173.

PMID:
26931682
25.

Linked coupled cluster Monte Carlo.

Franklin RS, Spencer JS, Zoccante A, Thom AJ.

J Chem Phys. 2016 Jan 28;144(4):044111. doi: 10.1063/1.4940317.

PMID:
26827206
26.

Spatial epidemiology and serologic cohorts increase the early detection of leprosy.

Barreto JG, Bisanzio D, Frade MA, Moraes TM, Gobbo AR, de Souza Guimarães L, da Silva MB, Vazquez-Prokopec GM, Spencer JS, Kitron U, Salgado CG.

BMC Infect Dis. 2015 Nov 16;15:527. doi: 10.1186/s12879-015-1254-8.

27.

Longitudinal immune profiles in type 1 leprosy reactions in Bangladesh, Brazil, Ethiopia and Nepal.

Khadge S, Banu S, Bobosha K, van der Ploeg-van Schip JJ, Goulart IM, Thapa P, Kunwar CB, van Meijgaarden KE, van den Eeden SJ, Wilson L, Kabir S, Dey H, Goulart LR, Lobato J, Carvalho W, Bekele Y, Franken KL, Aseffa A, Spencer JS, Oskam L, Otttenhoff TH, Hagge DA, Geluk A.

BMC Infect Dis. 2015 Oct 28;15:477. doi: 10.1186/s12879-015-1128-0.

28.

Interaction picture density matrix quantum Monte Carlo.

Malone FD, Blunt NS, Shepherd JJ, Lee DK, Spencer JS, Foulkes WM.

J Chem Phys. 2015 Jul 28;143(4):044116. doi: 10.1063/1.4927434.

29.

The presence of a galactosamine substituent on the arabinogalactan of Mycobacterium tuberculosis abrogates full maturation of human peripheral blood monocyte-derived dendritic cells and increases secretion of IL-10.

Wheat WH, Dhouib R, Angala SK, Larrouy-Maumus G, Dobos K, Nigou J, Spencer JS, Jackson M.

Tuberculosis (Edinb). 2015 Jul;95(4):476-89. doi: 10.1016/j.tube.2015.04.002. Epub 2015 May 14.

30.

Semi-stochastic full configuration interaction quantum Monte Carlo: Developments and application.

Blunt NS, Smart SD, Kersten JA, Spencer JS, Booth GH, Alavi A.

J Chem Phys. 2015 May 14;142(18):184107. doi: 10.1063/1.4920975.

31.

Minimising biases in full configuration interaction quantum Monte Carlo.

Vigor WA, Spencer JS, Bearpark MJ, Thom AJ.

J Chem Phys. 2015 Mar 14;142(10):104101. doi: 10.1063/1.4913644.

32.

Long-term survival and virulence of Mycobacterium leprae in amoebal cysts.

Wheat WH, Casali AL, Thomas V, Spencer JS, Lahiri R, Williams DL, McDonnell GE, Gonzalez-Juarrero M, Brennan PJ, Jackson M.

PLoS Negl Trop Dis. 2014 Dec 18;8(12):e3405. doi: 10.1371/journal.pntd.0003405. eCollection 2014 Dec.

33.

IL-10 and NOS2 modulate antigen-specific reactivity and nerve infiltration by T cells in experimental leprosy.

Hagge DA, Scollard DM, Ray NA, Marks VT, Deming AT, Spencer JS, Adams LB.

PLoS Negl Trop Dis. 2014 Sep 11;8(9):e3149. doi: 10.1371/journal.pntd.0003149. eCollection 2014 Sep.

34.

Field-evaluation of a new lateral flow assay for detection of cellular and humoral immunity against Mycobacterium leprae.

Bobosha K, Tjon Kon Fat EM, van den Eeden SJ, Bekele Y, van der Ploeg-van Schip JJ, de Dood CJ, Dijkman K, Franken KL, Wilson L, Aseffa A, Spencer JS, Ottenhoff TH, Corstjens PL, Geluk A.

PLoS Negl Trop Dis. 2014 May 8;8(5):e2845. doi: 10.1371/journal.pntd.0002845. eCollection 2014 May.

35.

Spatial analysis spotlighting early childhood leprosy transmission in a hyperendemic municipality of the Brazilian Amazon region.

Barreto JG, Bisanzio D, Guimarães Lde S, Spencer JS, Vazquez-Prokopec GM, Kitron U, Salgado CG.

PLoS Negl Trop Dis. 2014 Feb 6;8(2):e2665. doi: 10.1371/journal.pntd.0002665. eCollection 2014 Feb.

36.

O-mannosylation of the Mycobacterium tuberculosis adhesin Apa is crucial for T cell antigenicity during infection but is expendable for protection.

Nandakumar S, Kannanganat S, Dobos KM, Lucas M, Spencer JS, Fang S, McDonald MA, Pohl J, Birkness K, Chamcha V, Ramirez MV, Plikaytis BB, Posey JE, Amara RR, Sable SB.

PLoS Pathog. 2013;9(10):e1003705. doi: 10.1371/journal.ppat.1003705. Epub 2013 Oct 10.

37.

Linear-scaling time-dependent density-functional theory in the linear response formalism.

Zuehlsdorff TJ, Hine ND, Spencer JS, Harrison NM, Riley DJ, Haynes PD.

J Chem Phys. 2013 Aug 14;139(6):064104. doi: 10.1063/1.4817330.

38.

PARK2 mediates interleukin 6 and monocyte chemoattractant protein 1 production by human macrophages.

de Léséleuc L, Orlova M, Cobat A, Girard M, Huong NT, Ba NN, Thuc NV, Truman R, Spencer JS, Adams L, Thai VH, Alcais A, Schurr E.

PLoS Negl Trop Dis. 2013;7(1):e2015. doi: 10.1371/journal.pntd.0002015. Epub 2013 Jan 17.

39.

The effect of quantization on the full configuration interaction quantum Monte Carlo sign problem.

Kolodrubetz MH, Spencer JS, Clark BK, Foulkes WM.

J Chem Phys. 2013 Jan 14;138(2):024110. doi: 10.1063/1.4773819.

40.

Identification of serological biomarkers of infection, disease progression and treatment efficacy for leprosy.

Spencer JS, Duthie MS, Geluk A, Balagon MF, Kim HJ, Wheat WH, Chatterjee D, Jackson M, Li W, Kurihara JN, Maghanoy A, Mallari I, Saunderson P, Brennan PJ, Dockrell HM.

Mem Inst Oswaldo Cruz. 2012 Dec;107 Suppl 1:79-89.

41.

Gene expression profile and immunological evaluation of unique hypothetical unknown proteins of Mycobacterium leprae by using quantitative real-time PCR.

Kim HJ, Prithiviraj K, Groathouse N, Brennan PJ, Spencer JS.

Clin Vaccine Immunol. 2013 Feb;20(2):181-90. doi: 10.1128/CVI.00419-12. Epub 2012 Dec 12.

42.

Pathogen-specific epitopes as epidemiological tools for defining the magnitude of Mycobacterium leprae transmission in areas endemic for leprosy.

Martins MV, Guimarães MM, Spencer JS, Hacker MA, Costa LS, Carvalho FM, Geluk A, van der Ploeg-van Schip JJ, Pontes MA, Gonçalves HS, de Morais JP, Bandeira TJ, Pessolani MC, Brennan PJ, Pereira GM.

PLoS Negl Trop Dis. 2012;6(4):e1616. doi: 10.1371/journal.pntd.0001616. Epub 2012 Apr 24.

43.

New biomarkers with relevance to leprosy diagnosis applicable in areas hyperendemic for leprosy.

Geluk A, Bobosha K, van der Ploeg-van Schip JJ, Spencer JS, Banu S, Martins MV, Cho SN, Franken KL, Kim HJ, Bekele Y, Uddin MK, Hadi SA, Aseffa A, Pessolani MC, Pereira GM, Dockrell HM, Ottenhoff TH.

J Immunol. 2012 May 15;188(10):4782-91. doi: 10.4049/jimmunol.1103452. Epub 2012 Apr 13.

44.

Development of a mouse food pad model for detection of sub clinical leprosy.

Lahiri R, Randhawa B, Franken KL, Duthie MS, Spencer JS, Geluk A, Krahenbuhl JL.

Lepr Rev. 2011 Dec;82(4):432-44.

PMID:
22439282
45.
46.

Comparison of three immunological tests for leprosy diagnosis and detection of subclinical infection.

Lobato J, Costa MP, Reis Ede M, Gonçalves MA, Spencer JS, Brennan PJ, Goulart LR, Goulart IM.

Lepr Rev. 2011 Dec;82(4):389-401.

PMID:
22439279
47.
48.

A bispecific antibody based assay shows potential for detecting tuberculosis in resource constrained laboratory settings.

Sarkar S, Tang XL, Das D, Spencer JS, Lowary TL, Suresh MR.

PLoS One. 2012;7(2):e32340. doi: 10.1371/journal.pone.0032340. Epub 2012 Feb 21.

49.

The sign problem and population dynamics in the full configuration interaction quantum Monte Carlo method.

Spencer JS, Blunt NS, Foulkes WM.

J Chem Phys. 2012 Feb 7;136(5):054110. doi: 10.1063/1.3681396.

PMID:
22320728
50.

Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli.

de la Paz Santangelo M, Gest PM, Guerin ME, Coinçon M, Pham H, Ryan G, Puckett SE, Spencer JS, Gonzalez-Juarrero M, Daher R, Lenaerts AJ, Schnappinger D, Therisod M, Ehrt S, Sygusch J, Jackson M.

J Biol Chem. 2011 Nov 18;286(46):40219-31. doi: 10.1074/jbc.M111.259440. Epub 2011 Sep 23.

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