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Items: 28

1.

Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models.

Brooks HB, Meier TI, Geeganage S, Fales KR, Thrasher KJ, Konicek SA, Spencer CD, Thibodeaux S, Foreman RT, Hui YH, Roth KD, Qian YW, Wang T, Luo S, Torrado A, Si C, Toth JL, Mc Cowan JR, Frimpong K, Lee MR, Dally RD, Shepherd TA, Durham TB, Wang Y, Wu Z, Iversen PW, Njoroge FG.

Sci Rep. 2018 Oct 18;8(1):15458. doi: 10.1038/s41598-018-33453-4.

2.

Influence of catastrophizing, anxiety, and depression on in-hospital opioid consumption, pain, and quality of recovery after adult spine surgery.

Dunn LK, Durieux ME, Fernández LG, Tsang S, Smith-Straesser EE, Jhaveri HF, Spanos SP, Thames MR, Spencer CD, Lloyd A, Stuart R, Ye F, Bray JP, Nemergut EC, Naik BI.

J Neurosurg Spine. 2018 Jan;28(1):119-126. doi: 10.3171/2017.5.SPINE1734. Epub 2017 Nov 10.

3.

Definitive activation of endogenous antitumor immunity by repetitive cycles of cyclophosphamide with interspersed Toll-like receptor agonists.

Manrique SZ, Dominguez AL, Mirza N, Spencer CD, Bradley JM, Finke JH, Lee JJ, Pease LR, Gendler SJ, Cohen PA.

Oncotarget. 2016 Jul 12;7(28):42919-42942. doi: 10.18632/oncotarget.10190.

4.

Myeloid-derived suppressor cells adhere to physiologic STAT3- vs STAT5-dependent hematopoietic programming, establishing diverse tumor-mediated mechanisms of immunologic escape.

Cohen PA, Ko JS, Storkus WJ, Spencer CD, Bradley JM, Gorman JE, McCurry DB, Zorro-Manrique S, Dominguez AL, Pathangey LB, Rayman PA, Rini BI, Gendler SJ, Finke JH.

Immunol Invest. 2012;41(6-7):680-710. doi: 10.3109/08820139.2012.703745. Review.

5.

Robot-assisted laparoscopic pyeloplasty for the management of pelvi-ureteric junction obstruction in horseshoe kidneys: initial experience.

Spencer CD, Sairam K, Challacombe B, Murphy D, Dasgupta P.

J Robot Surg. 2009 Jun;3(2):99-102. doi: 10.1007/s11701-009-0142-x. Epub 2009 Jun 6.

PMID:
27638223
6.

Assessment of the reliability of data collected for the Department of Veterans Affairs national surgical quality improvement program.

Davis CL, Pierce JR, Henderson W, Spencer CD, Tyler C, Langberg R, Swafford J, Felan GS, Kearns MA, Booker B.

J Am Coll Surg. 2007 Apr;204(4):550-60. Epub 2007 Mar 2.

PMID:
17382213
7.

Structure-based design of a new class of highly selective aminoimidazo[1,2-a]pyridine-based inhibitors of cyclin dependent kinases.

Hamdouchi C, Zhong B, Mendoza J, Collins E, Jaramillo C, De Diego JE, Robertson D, Spencer CD, Anderson BD, Watkins SA, Zhang F, Brooks HB.

Bioorg Med Chem Lett. 2005 Apr 1;15(7):1943-7.

PMID:
15780638
8.

Aminoimidazo[1,2-a]pyridines as a new structural class of cyclin-dependent kinase inhibitors. Part 1: Design, synthesis, and biological evaluation.

Jaramillo C, de Diego JE, Hamdouchi C, Collins E, Keyser H, Sánchez-Martínez C, del Prado M, Norman B, Brooks HB, Watkins SA, Spencer CD, Dempsey JA, Anderson BD, Campbell RM, Leggett T, Patel B, Schultz RM, Espinosa J, Vieth M, Zhang F, Timm DE.

Bioorg Med Chem Lett. 2004 Dec 20;14(24):6095-9.

PMID:
15546737
9.

Preparation of novel aza-1,7-annulated indoles and their conversion to potent indolocarbazole kinase inhibitors.

Al-awar RS, Ray JE, Hecker KA, Joseph S, Huang J, Shih C, Brooks HB, Spencer CD, Watkins SA, Schultz RM, Considine EL, Faul MM, Sullivan KA, Kolis SP, Carr MA, Zhang F.

Bioorg Med Chem Lett. 2004 Aug 2;14(15):3925-8.

PMID:
15225699
10.

1,7-annulated indolocarbazoles as cyclin-dependent kinase inhibitors.

Al-awar RS, Ray JE, Hecker KA, Huang J, Waid PP, Shih C, Brooks HB, Spencer CD, Watkins SA, Patel BR, Stamm NB, Ogg CA, Schultz RM, Considine EL, Faul MM, Sullivan KA, Kolis SP, Grutsch JL, Joseph S.

Bioorg Med Chem Lett. 2004 Jun 21;14(12):3217-20.

PMID:
15149678
11.

Synthesis of 1,7-annulated indoles and their applications in the studies of cyclin dependent kinase inhibitors.

Zhu G, Conner SE, Zhou X, Chan HK, Shih C, Engler TA, Al-Awar RS, Brooks HB, Watkins SA, Spencer CD, Schultz RM, Dempsey JA, Considine EL, Patel BR, Ogg CA, Vasudevan V, Lytle ML.

Bioorg Med Chem Lett. 2004 Jun 21;14(12):3057-61.

PMID:
15149644
12.

The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo[1,2-a]pyridines.

Hamdouchi C, Keyser H, Collins E, Jaramillo C, De Diego JE, Spencer CD, Dempsey JA, Anderson BD, Leggett T, Stamm NB, Schultz RM, Watkins SA, Cocke K, Lemke S, Burke TF, Beckmann RP, Dixon JT, Gurganus TM, Rankl NB, Houck KA, Zhang F, Vieth M, Espinosa J, Timm DE, Campbell RM, Patel BK, Brooks HB.

Mol Cancer Ther. 2004 Jan;3(1):1-9.

13.

Studies on cyclin-dependent kinase inhibitors: indolo-[2,3-a]pyrrolo[3,4-c]carbazoles versus bis-indolylmaleimides.

Sanchez-Martinez C, Shih C, Zhu G, Li T, Brooks HB, Patel BK, Schultz RM, DeHahn TB, Spencer CD, Watkins SA, Ogg CA, Considine E, Dempsey JA, Zhang F.

Bioorg Med Chem Lett. 2003 Nov 3;13(21):3841-6.

PMID:
14552792
14.

Aryl[a]pyrrolo[3,4-c]carbazoles as selective cyclin D1-CDK4 inhibitors.

Sanchez-Martinez C, Shih C, Faul MM, Zhu G, Paal M, Somoza C, Li T, Kumrich CA, Winneroski LL, Xun Z, Brooks HB, Patel BK, Schultz RM, DeHahn TB, Spencer CD, Watkins SA, Considine E, Dempsey JA, Ogg CA, Campbell RM, Anderson BA, Wagner J.

Bioorg Med Chem Lett. 2003 Nov 3;13(21):3835-9.

PMID:
14552791
15.

Novel, potent and selective cyclin D1/CDK4 inhibitors: indolo[6,7-a]pyrrolo[3,4-c]carbazoles.

Engler TA, Furness K, Malhotra S, Sanchez-Martinez C, Shih C, Xie W, Zhu G, Zhou X, Conner S, Faul MM, Sullivan KA, Kolis SP, Brooks HB, Patel B, Schultz RM, DeHahn TB, Kirmani K, Spencer CD, Watkins SA, Considine EL, Dempsey JA, Ogg CA, Stamm NB, Anderson BD, Campbell RM, Vasudevan V, Lytle ML.

Bioorg Med Chem Lett. 2003 Jul 21;13(14):2261-7.

PMID:
12824014
16.

Synthesis, structure-activity relationship, and biological studies of indolocarbazoles as potent cyclin D1-CDK4 inhibitors.

Zhu G, Conner SE, Zhou X, Shih C, Li T, Anderson BD, Brooks HB, Campbell RM, Considine E, Dempsey JA, Faul MM, Ogg C, Patel B, Schultz RM, Spencer CD, Teicher B, Watkins SA.

J Med Chem. 2003 May 22;46(11):2027-30.

PMID:
12747775
17.

Synthesis of quinolinyl/isoquinolinyl[a]pyrrolo [3,4-c] carbazoles as cyclin D1/CDK4 inhibitors.

Zhu G, Conner S, Zhou X, Shih C, Brooks HB, Considine E, Dempsey JA, Ogg C, Patel B, Schultz RM, Spencer CD, Teicher B, Watkins SA.

Bioorg Med Chem Lett. 2003 Apr 7;13(7):1231-5.

PMID:
12657252
18.

The QAU: friend, not foe.

Sewell AF, Spencer CD.

J Clin Pharmacol. 1991 Jun;31(6):509-11. No abstract available.

PMID:
1880214
20.

Vinca alkaloids for idiopathic thrombocytopenic purpura.

Pillai MV, Spencer CD, Sonoda T.

Ann Intern Med. 1984 Jul;101(1):149-50. No abstract available.

PMID:
6539577
21.

Medulloblastoma metastatic to the marrow. Report of four cases and review of the literature.

Spencer CD, Weiss RB, Van Eys J, Cohen P, Edwards B.

J Neurooncol. 1984;2(3):223-35.

PMID:
6502196
22.

Treatment of postpartum hemolytic uremic syndrome with plasma exchange.

Spencer CD, Crane FM, Kumar JR, Alving BM.

JAMA. 1982 May 28;247(20):2808-9. No abstract available.

PMID:
7200534
23.

Nontoxic staphylococcal pneumonia with empyema in a renal transplant recipient.

Spencer CD, Crawford GE.

West J Med. 1982 Feb;136(2):147-9. No abstract available.

24.

HMO development for primary care team teaching of medical and nursing students.

Osterweis M, Chickadonz G, Huntley RR, Spencer CD.

J Med Educ. 1980 Sep;55(9):743-50.

PMID:
7441690
25.

Views: custodial care under Medicare.

Spencer CD.

Employee Benefit Plan Rev. 1976 Apr;30(10):5-6. No abstract available.

PMID:
829319
26.

Complications of transtracheal aspiration.

Spencer CD, Beaty HN.

N Engl J Med. 1972 Feb 10;286(6):304-6. No abstract available.

PMID:
5007229
27.

AN APPROACH TO MENTAL HEALTH CONSULTATION WITHIN THE MILITARY.

SPENCER CD, GRAY B.

Mil Med. 1965 Jul;130:691-4. No abstract available.

PMID:
14301147
28.

WHAT PRICE LEADERSHIP?DISTRESS IN A PEACETIME MILITARY UNIT.

SPENCER CD, GRAY B.

Mil Med. 1965 Mar;130:247-50. No abstract available.

PMID:
14258134

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