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Items: 19

1.

Mass Spectrometry-Based Biomarkers in Drug Development.

Robinson MR, Miller RA, Spellman DS.

Adv Exp Med Biol. 2019;1140:435-449. doi: 10.1007/978-3-030-15950-4_25. Review.

PMID:
31347063
2.

Direct quantitation of therapeutic antibodies for pharmacokinetic studies using immuno-purification and intact mass analysis.

Vasicek LA, Zhu X, Spellman DS, Bateman KP.

Bioanalysis. 2019 Feb 8. doi: 10.4155/bio-2018-0240. [Epub ahead of print]

PMID:
30734579
3.

Quantitation of a Therapeutic Antibody in Serum Using Intact Sequential Affinity Capture, Trypsin Digestion, and LC-MS/MS.

Vasicek LA, Spellman DS, Hsieh S, Seghezzi W, Zhang S, Santostefano M, Bateman KP.

Anal Chem. 2018 Jan 2;90(1):866-871. doi: 10.1021/acs.analchem.7b03716. Epub 2017 Dec 20.

PMID:
29206445
4.

Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain.

Hanamura K, Washburn HR, Sheffler-Collins SI, Xia NL, Henderson N, Tillu DV, Hassler S, Spellman DS, Zhang G, Neubert TA, Price TJ, Dalva MB.

PLoS Biol. 2017 Jul 18;15(7):e2002457. doi: 10.1371/journal.pbio.2002457. eCollection 2017 Jul.

5.

Automated DBS microsampling, microscale automation and microflow LC-MS for therapeutic protein PK.

Zhang Q, Tomazela D, Vasicek LA, Spellman DS, Beaumont M, Shyong B, Kenny J, Fauty S, Fillgrove K, Harrelson J, Bateman KP.

Bioanalysis. 2016 Apr;8(7):649-59. doi: 10.4155/bio-2015-0006. Epub 2016 Mar 15.

PMID:
26977979
6.

Development and evaluation of a multiplexed mass spectrometry based assay for measuring candidate peptide biomarkers in Alzheimer's Disease Neuroimaging Initiative (ADNI) CSF.

Spellman DS, Wildsmith KR, Honigberg LA, Tuefferd M, Baker D, Raghavan N, Nairn AC, Croteau P, Schirm M, Allard R, Lamontagne J, Chelsky D, Hoffmann S, Potter WZ; Alzheimer's Disease Neuroimaging Initiative; Foundation for NIH (FNIH) Biomarkers Consortium CSF Proteomics Project Team.

Proteomics Clin Appl. 2015 Aug;9(7-8):715-31. doi: 10.1002/prca.201400178. Epub 2015 Apr 24.

7.

Quantitation of human peptides and proteins via MS: review of analytically validated assays.

Chappell DL, Lassman ME, McAvoy T, Lin M, Spellman DS, Laterza OF.

Bioanalysis. 2014;6(13):1843-57. doi: 10.4155/bio.14.145. Review.

PMID:
25157489
8.

Generic automated method for liquid chromatography-multiple reaction monitoring mass spectrometry based monoclonal antibody quantitation for preclinical pharmacokinetic studies.

Zhang Q, Spellman DS, Song Y, Choi B, Hatcher NG, Tomazela D, Beaumont M, Tabrizifard M, Prabhavalkar D, Seghezzi W, Harrelson J, Bateman KP.

Anal Chem. 2014 Sep 2;86(17):8776-84. doi: 10.1021/ac5019827. Epub 2014 Aug 14.

PMID:
25010922
9.

Mass spectrometry-based biomarkers in drug development.

Miller RA, Spellman DS.

Adv Exp Med Biol. 2014;806:341-59. doi: 10.1007/978-3-319-06068-2_16. Review.

PMID:
24952191
10.

Quantitative proteomics in laser capture microdissected sleep nuclei from rat brain.

Miller RA, Winrow CJ, Spellman DS, Song Q, Reiss DR, Conway JP, Taylor RR, Coleman PJ, Hendrickson RC, Renger JJ.

J Neurogenet. 2014 Mar-Jun;28(1-2):136-45. doi: 10.3109/01677063.2014.883389. Epub 2014 Mar 3.

11.

Quantification of tau in cerebrospinal fluid by immunoaffinity enrichment and tandem mass spectrometry.

McAvoy T, Lassman ME, Spellman DS, Ke Z, Howell BJ, Wong O, Zhu L, Tanen M, Struyk A, Laterza OF.

Clin Chem. 2014 Apr;60(4):683-9. doi: 10.1373/clinchem.2013.216515. Epub 2014 Feb 24.

12.

Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac.

Deinhardt K, Kim T, Spellman DS, Mains RE, Eipper BA, Neubert TA, Chao MV, Hempstead BL.

Sci Signal. 2011 Dec 6;4(202):ra82. doi: 10.1126/scisignal.2002060.

13.

Quantitative analysis of intact apolipoproteins in human HDL by top-down differential mass spectrometry.

Mazur MT, Cardasis HL, Spellman DS, Liaw A, Yates NA, Hendrickson RC.

Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7728-33. doi: 10.1073/pnas.0910776107. Epub 2010 Apr 13.

14.

Histoplasma capsulatum proteome response to decreased iron availability.

Winters MS, Spellman DS, Chan Q, Gomez FJ, Hernandez M, Catron B, Smulian AG, Neubert TA, Deepe GS Jr.

Proteome Sci. 2008 Dec 24;6:36. doi: 10.1186/1477-5956-6-36.

15.

Stable isotopic labeling by amino acids in cultured primary neurons: application to brain-derived neurotrophic factor-dependent phosphotyrosine-associated signaling.

Spellman DS, Deinhardt K, Darie CC, Chao MV, Neubert TA.

Mol Cell Proteomics. 2008 Jun;7(6):1067-76. doi: 10.1074/mcp.M700387-MCP200. Epub 2008 Feb 6.

16.

Analysis of electroblotted proteins by mass spectrometry: protein identification after Western blotting.

Luque-Garcia JL, Zhou G, Spellman DS, Sun TT, Neubert TA.

Mol Cell Proteomics. 2008 Feb;7(2):308-14. Epub 2007 Oct 15.

17.

Characterization by tandem mass spectrometry of stable cysteine sulfenic acid in a cysteine switch peptide of matrix metalloproteinases.

Shetty V, Spellman DS, Neubert TA.

J Am Soc Mass Spectrom. 2007 Aug;18(8):1544-51. Epub 2007 May 24.

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