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Items: 1 to 50 of 79

1.

Alternative activation of human macrophages enhances tissue factor expression and production of extracellular vesicles.

Hohensinner PJ, Mayer J, Kichbacher J, Kral-Pointner J, Thaler B, Kaun C, Hell L, Haider P, Mussbacher M, Schmid JA, Stojkovic S, Demyanets S, Fischer MB, Huber K, Wöran K, Hengstenberg C, Speidl WS, Oehler R, Pabinger I, Wojta J.

Haematologica. 2020 Jan 23. pii: haematol.2019.220210. doi: 10.3324/haematol.2019.220210. [Epub ahead of print]

2.

Lipoprotein(a) plasma levels are not associated with survival after acute coronary syndromes: An observational cohort study.

Roth C, Krychtiuk KA, Gangl C, Schrutka L, Distelmaier K, Wojta J, Hengstenberg C, Berger R, Speidl WS.

PLoS One. 2020 Jan 9;15(1):e0227054. doi: 10.1371/journal.pone.0227054. eCollection 2020.

3.

Neutrophil extracellular traps and monocyte subsets at the culprit lesion site of myocardial infarction patients.

Mangold A, Hofbauer TM, Ondracek AS, Artner T, Scherz T, Speidl WS, Krychtiuk KA, Sadushi-Kolici R, Jakowitsch J, Lang IM.

Sci Rep. 2019 Nov 8;9(1):16304. doi: 10.1038/s41598-019-52671-y.

4.

Toll like receptor 2 and 9 expression on circulating neutrophils is associated with increased mortality in critically ill patients.

Lenz M, Draxler DF, Zhang C, Kassem M, Kastl SP, Niessner A, Huber K, Wojta J, Heinz G, Speidl WS, Krychtiuk KA.

Shock. 2019 Nov 4. doi: 10.1097/SHK.0000000000001467. [Epub ahead of print]

PMID:
31688663
5.

Growth differentiation factor-15 predicts poor survival after cardiac arrest.

Richter B, Uray T, Krychtiuk KA, Schriefl C, Lenz M, Nürnberger A, Kastl SP, Wojta J, Heinz G, Schwameis M, Speidl WS.

Resuscitation. 2019 Oct;143:22-28. doi: 10.1016/j.resuscitation.2019.07.028. Epub 2019 Aug 5.

PMID:
31394153
6.

Protease-Activated Receptors 1 and 3 are Differentially Expressed on Human Monocyte Subsets and are Upregulated by Lipopolysaccharide Ex Vivo and In Vivo.

Thaler B, Hohensinner PJ, Baumgartner J, Haider P, Krychtiuk KA, Schörgenhofer C, Jilma B, Hell L, Fischer MB, Huber K, Hengstenberg C, Speidl WS, Wojta J.

Thromb Haemost. 2019 Sep;119(9):1394-1402. doi: 10.1055/s-0039-1692219. Epub 2019 Jul 10.

7.

Differential expression of Plg-RKT and its effects on migration of proinflammatory monocyte and macrophage subsets.

Thaler B, Baik N, Hohensinner PJ, Baumgartner J, Panzenböck A, Stojkovic S, Demyanets S, Huk I, Rega-Kaun G, Kaun C, Prager M, Fischer MB, Huber K, Speidl WS, Parmer RJ, Miles LA, Wojta J.

Blood. 2019 Aug 8;134(6):561-567. doi: 10.1182/blood.2018850420. Epub 2019 Jun 20.

8.

Release of mitochondrial DNA is associated with mortality in severe acute heart failure.

Krychtiuk KA, Wurm R, Ruhittel S, Lenz M, Huber K, Wojta J, Heinz G, Hülsmann M, Speidl WS.

Eur Heart J Acute Cardiovasc Care. 2019 Jan 11:2048872618823405. doi: 10.1177/2048872618823405. [Epub ahead of print]

PMID:
30632383
9.

Prevention is back in the spotlight - Highlights from American Heart Association Scientific Sessions 2018.

Krychtiuk KA, Speidl WS.

Eur J Prev Cardiol. 2019 Mar;26(5):502-506. doi: 10.1177/2047487318820977. Epub 2018 Dec 22. No abstract available.

PMID:
30580578
10.

Statin treatment reduces matrix degradation capacity of proinflammatory polarized macrophages.

Hohensinner PJ, Baumgartner J, Ebenbauer B, Thaler B, Fischer MB, Huber K, Speidl WS, Wojta J.

Vascul Pharmacol. 2018 Nov;110:49-54. doi: 10.1016/j.vph.2018.08.003. Epub 2018 Aug 9.

11.

Intestinal Fatty Acid Binding Protein is Associated With Mortality in Patients With Acute Heart Failure or Cardiogenic Shock.

Kastl SP, Krychtiuk KA, Lenz M, Distelmaier K, Goliasch G, Huber K, Wojta J, Heinz G, Speidl WS.

Shock. 2019 Apr;51(4):410-415. doi: 10.1097/SHK.0000000000001195.

PMID:
29847500
12.

Pretreatment With Argon Protects Human Cardiac Myocyte-Like Progenitor Cells from Oxygen Glucose Deprivation-Induced Cell Death by Activation of AKT and Differential Regulation of Mapkinases.

Qi H, Soto-Gonzalez L, Krychtiuk KA, Ruhittel S, Kaun C, Speidl WS, Kiss A, Podesser BK, Yao S, Markstaller K, Klein KU, Tretter V.

Shock. 2018 May;49(5):556-563. doi: 10.1097/SHK.0000000000000998.

PMID:
29658909
13.

N-terminal pro-brain natriuretic peptide and high-sensitivity troponin T exhibit additive prognostic value for the outcome of critically ill patients.

Lenz M, Krychtiuk KA, Goliasch G, Distelmaier K, Wojta J, Heinz G, Speidl WS.

Eur Heart J Acute Cardiovasc Care. 2018 Apr 1:2048872618768088. doi: 10.1177/2048872618768088. [Epub ahead of print]

PMID:
29617154
14.

Predictive value of low interleukin-33 in critically ill patients.

Krychtiuk KA, Stojkovic S, Lenz M, Brekalo M, Huber K, Wojta J, Heinz G, Demyanets S, Speidl WS.

Cytokine. 2018 Mar;103:109-113. doi: 10.1016/j.cyto.2017.09.017. Epub 2017 Sep 30.

PMID:
28974430
15.

Clopidogrel in Critically Ill Patients.

Schoergenhofer C, Hobl EL, Schellongowski P, Heinz G, Speidl WS, Siller-Matula JM, Schmid M, Sunder-Plaßmann R, Stimpfl T, Hackl M, Jilma B.

Clin Pharmacol Ther. 2018 Feb;103(2):217-223. doi: 10.1002/cpt.878. Epub 2017 Nov 3.

16.

PAI-1 (Plasminogen Activator Inhibitor-1) Expression Renders Alternatively Activated Human Macrophages Proteolytically Quiescent.

Hohensinner PJ, Baumgartner J, Kral-Pointner JB, Uhrin P, Ebenbauer B, Thaler B, Doberer K, Stojkovic S, Demyanets S, Fischer MB, Huber K, Schabbauer G, Speidl WS, Wojta J.

Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1913-1922. doi: 10.1161/ATVBAHA.117.309383. Epub 2017 Aug 17.

17.

Prasugrel in critically ill patients.

Schoergenhofer C, Hobl EL, Staudinger T, Speidl WS, Heinz G, Siller-Matula J, Zauner C, Reiter B, Kubica J, Jilma B.

Thromb Haemost. 2017 Aug 1;117(8):1582-1587. doi: 10.1160/TH17-03-0154. Epub 2017 Jul 6.

18.

Acetylsalicylic acid in critically ill patients: a cross-sectional and a randomized trial.

Schoergenhofer C, Hobl EL, Schwameis M, Gelbenegger G, Staudinger T, Heinz G, Speidl WS, Zauner C, Reiter B, Lang I, Jilma B.

Eur J Clin Invest. 2017 Jul;47(7):504-512. doi: 10.1111/eci.12771. Epub 2017 Jun 20.

19.

Anti-thrombotic and pro-fibrinolytic effects of levosimendan in human endothelial cells in vitro.

Krychtiuk KA, Kaun C, Hohensinner PJ, Stojkovic S, Seigner J, Kastl SP, Zuckermann A, Eppel W, Rauscher S, de Martin R, Maurer G, Huber K, Wojta J, Speidl WS.

Vascul Pharmacol. 2017 Mar;90:44-50. doi: 10.1016/j.vph.2017.02.003. Epub 2017 Feb 10.

PMID:
28192257
20.

Copeptin Predicts Mortality in Critically Ill Patients.

Krychtiuk KA, Honeder MC, Lenz M, Maurer G, Wojta J, Heinz G, Huber K, Speidl WS.

PLoS One. 2017 Jan 24;12(1):e0170436. doi: 10.1371/journal.pone.0170436. eCollection 2017.

21.

Monocyte subset distribution is associated with mortality in critically ill patients.

Krychtiuk KA, Lenz M, Koller L, Honeder MC, Wutzlhofer L, Zhang C, Chi L, Maurer G, Niessner A, Huber K, Wojta J, Heinz G, Speidl WS.

Thromb Haemost. 2016 Oct 28;116(5):949-957. Epub 2016 Sep 8.

PMID:
27604519
22.

Differential in vivo activation of monocyte subsets during low-grade inflammation through experimental endotoxemia in humans.

Thaler B, Hohensinner PJ, Krychtiuk KA, Matzneller P, Koller L, Brekalo M, Maurer G, Huber K, Zeitlinger M, Jilma B, Wojta J, Speidl WS.

Sci Rep. 2016 Jul 22;6:30162. doi: 10.1038/srep30162.

23.

Expert position paper on prolonged dual antiplatelet therapy in secondary prevention following myocardial infarction.

Weiss TW, Aichinger J, Huber K, Speidl WS, Watzinger N, Zweiker R, Alber HF.

Wien Klin Wochenschr. 2016 Jun;128(11-12):450-7. doi: 10.1007/s00508-016-1016-7. Epub 2016 Jun 9. Review.

24.

Premature myocardial infarction is strongly associated with increased levels of remnant cholesterol.

Goliasch G, Wiesbauer F, Blessberger H, Demyanets S, Wojta J, Huber K, Maurer G, Schillinger M, Speidl WS.

J Clin Lipidol. 2015 Nov-Dec;9(6):801-806.e1. doi: 10.1016/j.jacl.2015.08.009. Epub 2015 Aug 29.

PMID:
26687701
25.

G-CSF Predicts Cardiovascular Events in Patients with Stable Coronary Artery Disease.

Katsaros KM, Speidl WS, Demyanets S, Kastl SP, Krychtiuk KA, Wonnerth A, Zorn G, Tentzeris I, Farhan S, Maurer G, Wojta J, Huber K.

PLoS One. 2015 Nov 10;10(11):e0142532. doi: 10.1371/journal.pone.0142532. eCollection 2015.

26.

Mitochondrial DNA and Toll-Like Receptor-9 Are Associated With Mortality in Critically Ill Patients.

Krychtiuk KA, Ruhittel S, Hohensinner PJ, Koller L, Kaun C, Lenz M, Bauer B, Wutzlhofer L, Draxler DF, Maurer G, Huber K, Wojta J, Heinz G, Niessner A, Speidl WS.

Crit Care Med. 2015 Dec;43(12):2633-41. doi: 10.1097/CCM.0000000000001311.

PMID:
26448617
27.

Monocyte subset distribution in patients with stable atherosclerosis and elevated levels of lipoprotein(a).

Krychtiuk KA, Kastl SP, Hofbauer SL, Wonnerth A, Goliasch G, Ozsvar-Kozma M, Katsaros KM, Maurer G, Huber K, Dostal E, Binder CJ, Pfaffenberger S, Oravec S, Wojta J, Speidl WS.

J Clin Lipidol. 2015 Jul-Aug;9(4):533-41. doi: 10.1016/j.jacl.2015.04.005. Epub 2015 Apr 25.

28.

Association of small dense LDL serum levels and circulating monocyte subsets in stable coronary artery disease.

Krychtiuk KA, Kastl SP, Pfaffenberger S, Lenz M, Hofbauer SL, Wonnerth A, Koller L, Katsaros KM, Pongratz T, Goliasch G, Niessner A, Gaspar L, Huber K, Maurer G, Dostal E, Wojta J, Oravec S, Speidl WS.

PLoS One. 2015 Apr 7;10(4):e0123367. doi: 10.1371/journal.pone.0123367. eCollection 2015.

29.

Variation of lipoprotein(a) plasma levels after premature myocardial infarction.

Goliasch G, Wiesbauer F, Blessberger H, Maurer G, Derfler K, Speidl WS.

Int J Cardiol. 2015;186:5-6. doi: 10.1016/j.ijcard.2015.03.211. Epub 2015 Mar 18. No abstract available.

PMID:
25804454
30.

Small high-density lipoprotein is associated with monocyte subsets in stable coronary artery disease.

Krychtiuk KA, Kastl SP, Pfaffenberger S, Pongratz T, Hofbauer SL, Wonnerth A, Katsaros KM, Goliasch G, Gaspar L, Huber K, Maurer G, Dostal E, Oravec S, Wojta J, Speidl WS.

Atherosclerosis. 2014 Dec;237(2):589-96. doi: 10.1016/j.atherosclerosis.2014.10.015. Epub 2014 Oct 18.

31.

Levosimendan exerts anti-inflammatory effects on cardiac myocytes and endothelial cells in vitro.

Krychtiuk KA, Watzke L, Kaun C, Buchberger E, Hofer-Warbinek R, Demyanets S, Pisoni J, Kastl SP, Rauscher S, Gröger M, Aliabadi A, Zuckermann A, Maurer G, de Martin R, Huber K, Wojta J, Speidl WS.

Thromb Haemost. 2015 Feb;113(2):350-62. doi: 10.1160/TH14-06-0549. Epub 2014 Oct 2.

PMID:
25273157
32.

Soluble ST2 and interleukin-33 levels in coronary artery disease: relation to disease activity and adverse outcome.

Demyanets S, Speidl WS, Tentzeris I, Jarai R, Katsaros KM, Farhan S, Krychtiuk KA, Wonnerth A, Weiss TW, Huber K, Wojta J.

PLoS One. 2014 Apr 21;9(4):e95055. doi: 10.1371/journal.pone.0095055. eCollection 2014.

33.

An increase of interleukin-33 serum levels after coronary stent implantation is associated with coronary in-stent restenosis.

Demyanets S, Tentzeris I, Jarai R, Katsaros KM, Farhan S, Wonnerth A, Weiss TW, Wojta J, Speidl WS, Huber K.

Cytokine. 2014 Jun;67(2):65-70. doi: 10.1016/j.cyto.2014.02.014. Epub 2014 Mar 27.

34.

Glycoprotein 130 polymorphism predicts soluble glycoprotein 130 levels.

Wonnerth A, Katsaros KM, Krychtiuk KA, Speidl WS, Kaun C, Thaler K, Huber K, Wojta J, Maurer G, Seljeflot I, Arnesen H, Weiss TW.

Metabolism. 2014 May;63(5):647-53. doi: 10.1016/j.metabol.2014.02.005. Epub 2014 Feb 14.

PMID:
24629561
35.

An increase of VEGF plasma levels is associated with restenosis of drug-eluting stents.

Katsaros KM, Kastl SP, Krychtiuk KA, Hutter R, Zorn G, Maurer G, Huber K, Wojta J, Christ G, Speidl WS.

EuroIntervention. 2014 Jun;10(2):224-30. doi: 10.4244/EIJV10I2A36.

36.

Novel small leucine-rich repeat protein podocan is a negative regulator of migration and proliferation of smooth muscle cells, modulates neointima formation, and is expressed in human atheroma.

Hutter R, Huang L, Speidl WS, Giannarelli C, Trubin P, Bauriedel G, Klotman ME, Fuster V, Badimon JJ, Klotman PE.

Circulation. 2013 Nov 26;128(22):2351-63. doi: 10.1161/CIRCULATIONAHA.113.004634. Epub 2013 Sep 16.

37.

Inflammation and coagulation in atherosclerosis.

Krychtiuk KA, Kastl SP, Speidl WS, Wojta J.

Hamostaseologie. 2013;33(4):269-82. doi: 10.5482/HAMO-13-07-0039. Epub 2013 Sep 17. Review.

PMID:
24043155
38.

Macrophages transmit potent proangiogenic effects of oxLDL in vitro and in vivo involving HIF-1α activation: a novel aspect of angiogenesis in atherosclerosis.

Hutter R, Speidl WS, Valdiviezo C, Sauter B, Corti R, Fuster V, Badimon JJ.

J Cardiovasc Transl Res. 2013 Aug;6(4):558-69. doi: 10.1007/s12265-013-9469-9. Epub 2013 May 10.

39.

Rhabdomyolysis during therapeutic hypothermia in a patient after successful cardio-pulmonary resuscitation.

Krychtiuk KA, Distelmaier K, Pfaffenberger S, Burger-Klepp U, Niessner A, Heinz G, Speidl WS.

Resuscitation. 2013 Jun;84(6):e79-80. doi: 10.1016/j.resuscitation.2013.02.018. Epub 2013 Mar 5. No abstract available.

PMID:
23470472
40.

Premature myocardial infarction is associated with low serum levels of Wnt-1.

Goliasch G, Wiesbauer F, Kastl SP, Katsaros KM, Blessberger H, Maurer G, Schillinger M, Huber K, Wojta J, Speidl WS.

Atherosclerosis. 2012 May;222(1):251-6. doi: 10.1016/j.atherosclerosis.2012.02.017. Epub 2012 Feb 16.

PMID:
22391424
41.

High soluble Fas and soluble Fas Ligand serum levels before stent implantation are protective against restenosis.

Katsaros KM, Wiesbauer F, Speidl WS, Kastl SP, Huber K, Zorn G, Niessner A, Glogar D, Maurer G, Wojta J.

Thromb Haemost. 2011 May;105(5):883-91. doi: 10.1160/TH10-09-0566. Epub 2011 Feb 28.

PMID:
21359408
42.

Complement in atherosclerosis: friend or foe?

Speidl WS, Kastl SP, Huber K, Wojta J.

J Thromb Haemost. 2011 Mar;9(3):428-40. doi: 10.1111/j.1538-7836.2010.04172.x. Review.

43.

The complement component C5a is present in human coronary lesions in vivo and induces the expression of MMP-1 and MMP-9 in human macrophages in vitro.

Speidl WS, Kastl SP, Hutter R, Katsaros KM, Kaun C, Bauriedel G, Maurer G, Huber K, Badimon JJ, Wojta J.

FASEB J. 2011 Jan;25(1):35-44. doi: 10.1096/fj.10-156083. Epub 2010 Sep 2.

PMID:
20813982
44.

Recombinant apolipoprotein A-I Milano rapidly reverses aortic valve stenosis and decreases leaflet inflammation in an experimental rabbit model.

Speidl WS, Cimmino G, Ibanez B, Elmariah S, Hutter R, Garcia MJ, Fuster V, Goldman ME, Badimon JJ.

Eur Heart J. 2010 Aug;31(16):2049-57. doi: 10.1093/eurheartj/ehq064. Epub 2010 Mar 19.

PMID:
20304838
45.

Increased restenosis rate after implantation of drug-eluting stents in patients with elevated serum activity of matrix metalloproteinase-2 and -9.

Katsaros KM, Kastl SP, Zorn G, Maurer G, Wojta J, Huber K, Christ G, Speidl WS.

JACC Cardiovasc Interv. 2010 Jan;3(1):90-7. doi: 10.1016/j.jcin.2009.10.023.

46.

Safe and sustained overexpression of functional apolipoprotein A-I/high-density lipoprotein in apolipoprotein A-I-null mice by muscular adeno-associated viral serotype 8 vector gene transfer.

Cimmino G, Chen W, Speidl WS, Giannarelli C, Ibanez B, Fuster V, Hajjar R, Walsh CE, Badimon JJ.

J Cardiovasc Pharmacol. 2009 Nov;54(5):405-11. doi: 10.1097/FJC.0b013e3181bad264.

PMID:
19701094
47.

Coronary late lumen loss of drug eluting stents is associated with increased serum levels of the complement components C3a and C5a.

Speidl WS, Katsaros KM, Kastl SP, Zorn G, Huber K, Maurer G, Wojta J, Christ G.

Atherosclerosis. 2010 Jan;208(1):285-9. doi: 10.1016/j.atherosclerosis.2009.07.030. Epub 2009 Jul 23.

PMID:
19683238
48.

Thrombin induces the expression of oncostatin M via AP-1 activation in human macrophages: a link between coagulation and inflammation.

Kastl SP, Speidl WS, Katsaros KM, Kaun C, Rega G, Assadian A, Hagmueller GW, Hoeth M, de Martin R, Ma Y, Maurer G, Huber K, Wojta J.

Blood. 2009 Sep 24;114(13):2812-8. doi: 10.1182/blood-2009-01-200915. Epub 2009 Aug 3.

PMID:
19652200
49.

Human cardiac fibroblasts express B-type natriuretic peptide: fluvastatin ameliorates its up-regulation by interleukin-1alpha, tumour necrosis factor-alpha and transforming growth factor-beta.

Jarai R, Kaun C, Weiss TW, Speidl WS, Rychli K, Maurer G, Huber K, Wojta J.

J Cell Mol Med. 2009 Nov-Dec;13(11-12):4415-21. doi: 10.1111/j.1582-4934.2009.00704.x. Epub 2009 Feb 17.

50.

Up-regulation of reverse cholesterol transport key players and rescue from global inflammation by ApoA-I(Milano).

Cimmino G, Ibanez B, Vilahur G, Speidl WS, Fuster V, Badimon L, Badimon JJ.

J Cell Mol Med. 2009 Sep;13(9B):3226-35. doi: 10.1111/j.1582-4934.2008.00614.x. Epub 2008 Dec 16.

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