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Items: 1 to 50 of 73

1.

Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites.

Di Mattia T, Wilhelm LP, Ikhlef S, Wendling C, Spehner D, Nominé Y, Giordano F, Mathelin C, Drin G, Tomasetto C, Alpy F.

EMBO Rep. 2018 Jul;19(7). pii: e45453. doi: 10.15252/embr.201745453. Epub 2018 Jun 1.

2.

Structure-function analyses unravel distinct effects of allosteric inhibitors of HIV-1 integrase on viral maturation and integration.

Bonnard D, Le Rouzic E, Eiler S, Amadori C, Orlov I, Bruneau JM, Brias J, Barbion J, Chevreuil F, Spehner D, Chasset S, Ledoussal B, Moreau F, Saïb A, Klaholz BP, Emiliani S, Ruff M, Zamborlini A, Benarous R.

J Biol Chem. 2018 Apr 20;293(16):6172-6186. doi: 10.1074/jbc.M117.816793. Epub 2018 Mar 5.

PMID:
29507092
3.

Structural features of the salivary gland hypertrophy virus of the tsetse fly revealed by cryo-electron microscopy and tomography.

Orlov I, Drillien R, Spehner D, Bergoin M, Abd-Alla AMM, Klaholz BP.

Virology. 2018 Jan 15;514:165-169. doi: 10.1016/j.virol.2017.11.016. Epub 2017 Nov 27.

PMID:
29190455
4.

The HIV-1 integrase-LEDGF allosteric inhibitor MUT-A: resistance profile, impairment of virus maturation and infectivity but without influence on RNA packaging or virus immunoreactivity.

Amadori C, van der Velden YU, Bonnard D, Orlov I, van Bel N, Le Rouzic E, Miralles L, Brias J, Chevreuil F, Spehner D, Chasset S, Ledoussal B, Mayr L, Moreau F, García F, Gatell J, Zamborlini A, Emiliani S, Ruff M, Klaholz BP, Moog C, Berkhout B, Plana M, Benarous R.

Retrovirology. 2017 Nov 9;14(1):50. doi: 10.1186/s12977-017-0373-2.

5.

Automatic segmentation of high pressure frozen and freeze-substituted mouse retina nuclei from FIB-SEM tomograms.

Hoang TV, Kizilyaprak C, Spehner D, Humbel BM, Schultz P.

J Struct Biol. 2017 Feb;197(2):123-134. doi: 10.1016/j.jsb.2016.10.005. Epub 2016 Oct 8.

PMID:
27725257
6.

Protein Delivery System Containing a Nickel-Immobilized Polymer for Multimerization of Affinity-Purified His-Tagged Proteins Enhances Cytosolic Transfer.

Postupalenko V, Desplancq D, Orlov I, Arntz Y, Spehner D, Mely Y, Klaholz BP, Schultz P, Weiss E, Zuber G.

Angew Chem Int Ed Engl. 2015 Sep 1;54(36):10583-6. doi: 10.1002/anie.201505437. Epub 2015 Jul 31.

PMID:
26230624
7.

Live cell immunogold labelling of RNA polymerase II.

Orlov I, Schertel A, Zuber G, Klaholz B, Drillien R, Weiss E, Schultz P, Spehner D.

Sci Rep. 2015 Feb 9;5:8324. doi: 10.1038/srep08324.

8.

Intracellular delivery of functionally active proteins using self-assembling pyridylthiourea-polyethylenimine.

Postupalenko V, Sibler AP, Desplancq D, Nominé Y, Spehner D, Schultz P, Weiss E, Zuber G.

J Control Release. 2014 Mar 28;178:86-94. doi: 10.1016/j.jconrel.2014.01.017. Epub 2014 Jan 27.

PMID:
24476809
9.

Protective effect of surfactant protein d in pulmonary vaccinia virus infection: implication of A27 viral protein.

Perino J, Thielens NM, Crouch E, Spehner D, Crance JM, Favier AL.

Viruses. 2013 Mar 21;5(3):928-53. doi: 10.3390/v5030928.

10.

The linker histone H1C contributes to the SCA7 nuclear phenotype.

Kizilyaprak C, Spehner D, Devys D, Schultz P.

Nucleus. 2011 Sep-Oct;2(5):444-54. doi: 10.4161/nucl.2.5.17843. Epub 2011 Sep 1.

PMID:
21970987
11.

Role of sulfatide in vaccinia virus infection.

Perino J, Foo CH, Spehner D, Cohen GH, Eisenberg RJ, Crance JM, Favier AL.

Biol Cell. 2011 Jul;103(7):319-31. doi: 10.1042/BC20110012.

PMID:
21554243
12.

Deletion of major nonessential genomic regions in the vaccinia virus Lister strain enhances attenuation without altering vaccine efficacy in mice.

Dimier J, Ferrier-Rembert A, Pradeau-Aubreton K, Hebben M, Spehner D, Favier AL, Gratier D, Garin D, Crance JM, Drillien R.

J Virol. 2011 May;85(10):5016-26. doi: 10.1128/JVI.02359-10. Epub 2011 Mar 2.

13.

Lung surfactant DPPG phospholipid inhibits vaccinia virus infection.

Perino J, Crouzier D, Spehner D, Debouzy JC, Garin D, Crance JM, Favier AL.

Antiviral Res. 2011 Jan;89(1):89-97. doi: 10.1016/j.antiviral.2010.11.009. Epub 2010 Nov 21.

PMID:
21095206
14.

In vivo chromatin organization of mouse rod photoreceptors correlates with histone modifications.

Kizilyaprak C, Spehner D, Devys D, Schultz P.

PLoS One. 2010 Jun 9;5(6):e11039. doi: 10.1371/journal.pone.0011039.

15.

Extracellular vesicles containing virus-encoded membrane proteins are a byproduct of infection with modified vaccinia virus Ankara.

Spehner D, Drillien R.

Virus Res. 2008 Oct;137(1):129-36. doi: 10.1016/j.virusres.2008.07.003. Epub 2008 Aug 13.

PMID:
18662728
16.

AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis.

Buj-Bello A, Fougerousse F, Schwab Y, Messaddeq N, Spehner D, Pierson CR, Durand M, Kretz C, Danos O, Douar AM, Beggs AH, Schultz P, Montus M, Denèfle P, Mandel JL.

Hum Mol Genet. 2008 Jul 15;17(14):2132-43. doi: 10.1093/hmg/ddn112. Epub 2008 Apr 22.

17.

Histone H3 tails containing dimethylated lysine and adjacent phosphorylated serine modifications adopt a specific conformation during mitosis and meiosis.

Eberlin A, Grauffel C, Oulad-Abdelghani M, Robert F, Torres-Padilla ME, Lambrot R, Spehner D, Ponce-Perez L, Würtz JM, Stote RH, Kimmins S, Schultz P, Dejaegere A, Tora L.

Mol Cell Biol. 2008 Mar;28(5):1739-54. doi: 10.1128/MCB.01180-07. Epub 2008 Jan 7.

18.

SAGA and a novel Drosophila export complex anchor efficient transcription and mRNA export to NPC.

Kurshakova MM, Krasnov AN, Kopytova DV, Shidlovskii YV, Nikolenko JV, Nabirochkina EN, Spehner D, Schultz P, Tora L, Georgieva SG.

EMBO J. 2007 Dec 12;26(24):4956-65. Epub 2007 Nov 22.

19.

High level protein expression in mammalian cells using a safe viral vector: modified vaccinia virus Ankara.

Hebben M, Brants J, Birck C, Samama JP, Wasylyk B, Spehner D, Pradeau K, Domi A, Moss B, Schultz P, Drillien R.

Protein Expr Purif. 2007 Dec;56(2):269-78. Epub 2007 Aug 24.

PMID:
17892951
20.

Semiclassical form factor for spectral and matrix element fluctuations of multidimensional chaotic systems.

Turek M, Spehner D, Müller S, Richter K.

Phys Rev E Stat Nonlin Soft Matter Phys. 2005 Jan;71(1 Pt 2):016210. Epub 2005 Jan 12.

PMID:
15697701
21.

[Viruses considered for a third generation anti-smallpox vaccine].

Drillien R, Spehner D, Garin D.

Med Mal Infect. 2004 Jun;34 Suppl 1:S51-4. French. No abstract available.

PMID:
15676248
22.

[Screening for Orthopoxviruses by electron microscopy].

Spehner D.

Med Mal Infect. 2004 Jun;34 Suppl 1:S40-2. French. No abstract available.

PMID:
15676244
23.

Modified vaccinia virus Ankara induces moderate activation of human dendritic cells.

Drillien R, Spehner D, Hanau D.

J Gen Virol. 2004 Aug;85(Pt 8):2167-75.

PMID:
15269355
24.

Appearance of the bona fide spiral tubule of ORF virus is dependent on an intact 10-kilodalton viral protein.

Spehner D, De Carlo S, Drillien R, Weiland F, Mildner K, Hanau D, Rziha HJ.

J Virol. 2004 Aug;78(15):8085-93.

25.

Reproduction of Langerin/CD207 traffic and Birbeck granule formation in a human cell line model.

McDermott R, Bausinger H, Fricker D, Spehner D, Proamer F, Lipsker D, Cazenave JP, Goud B, De La Salle H, Salamero J, Hanau D.

J Invest Dermatol. 2004 Jul;123(1):72-7.

26.

Cored tubules are present in human epidermal Langerhans cells.

Lipsker D, Ziylan U, McDermott R, Spehner D, Proamer F, Cazenave JP, Goud B, de la Salle H, Salamero J, Hanau D.

J Invest Dermatol. 2003 Mar;120(3):407-10.

27.
28.

Birbeck granules are subdomains of endosomal recycling compartment in human epidermal Langerhans cells, which form where Langerin accumulates.

Mc Dermott R, Ziylan U, Spehner D, Bausinger H, Lipsker D, Mommaas M, Cazenave JP, Raposo G, Goud B, de la Salle H, Salamero J, Hanau D.

Mol Biol Cell. 2002 Jan;13(1):317-35.

29.

Heat shock proteins 70 and 60 share common receptors which are expressed on human monocyte-derived but not epidermal dendritic cells.

Lipsker D, Ziylan U, Spehner D, Proamer F, Bausinger H, Jeannin P, Salamero J, Bohbot A, Cazenave JP, Drillien R, Delneste Y, Hanau D, de la Salle H.

Eur J Immunol. 2002 Feb;32(2):322-32.

30.

Characterization and quality control of recombinant adenovirus vectors for gene therapy.

Roitsch C, Achstetter T, Benchaibi M, Bonfils E, Cauet G, Gloeckler R, L'h te H, Keppi E, Nguyen M, Spehner D, Van Dorsselaer A, Malarme D.

J Chromatogr B Biomed Sci Appl. 2001 Mar 10;752(2):263-80.

PMID:
11270866
31.

Enveloped virus is the major virus form produced during productive infection with the modified vaccinia virus Ankara strain.

Spehner D, Drillien R, Proamer F, Houssais-Pêcheur C, Zanta MA, Geist M, Dott K, Balloul JM.

Virology. 2000 Jul 20;273(1):9-15.

32.

Schnitzler syndrome: heterogeneous immunopathological findings involving IgM-skin interactions.

Lipsker D, Spehner D, Drillien R, Schmitt P, Cribier B, Heid E, Humbel RL, Grosshans E.

Br J Dermatol. 2000 May;142(5):954-9.

PMID:
10809854
33.
34.

Inefficient measles virus budding in murine L.CD46 fibroblasts.

Vincent S, Spehner D, Manié S, Delorme R, Drillien R, Gerlier D.

Virology. 1999 Dec 20;265(2):185-95.

35.

A functional measles virus replication and transcription machinery encoded by the vaccinia virus genome.

Howley PM, Lafont B, Spehner D, Kaelin K, Billeter MA, Drillien R.

J Virol Methods. 1999 Apr;79(1):65-74.

PMID:
10328536
36.

Cutting edge: receptor-mediated endocytosis of heat shock proteins by professional antigen-presenting cells.

Arnold-Schild D, Hanau D, Spehner D, Schmid C, Rammensee HG, de la Salle H, Schild H.

J Immunol. 1999 Apr 1;162(7):3757-60.

37.

Fiberless recombinant adenoviruses: virus maturation and infectivity in the absence of fiber.

Legrand V, Spehner D, Schlesinger Y, Settelen N, Pavirani A, Mehtali M.

J Virol. 1999 Feb;73(2):907-19.

38.

A matrix-less measles virus is infectious and elicits extensive cell fusion: consequences for propagation in the brain.

Cathomen T, Mrkic B, Spehner D, Drillien R, Naef R, Pavlovic J, Aguzzi A, Billeter MA, Cattaneo R.

EMBO J. 1998 Jul 15;17(14):3899-908.

39.

Intracellular pathway for the generation of functional MHC class II peptide complexes in immature human dendritic cells.

Saudrais C, Spehner D, de la Salle H, Bohbot A, Cazenave JP, Goud B, Hanau D, Salamero J.

J Immunol. 1998 Mar 15;160(6):2597-607.

40.

A tyrosine-based signal present in Ig alpha mediates B cell receptor constitutive internalization.

Cassard S, Salamero J, Hanau D, Spehner D, Davoust J, Fridman WH, Bonnerot C.

J Immunol. 1998 Feb 15;160(4):1767-73.

41.
42.

Soluble CD16/Fc gamma RIII induces maturation of dendritic cells and production of several cytokines including IL-12.

de la Salle H, Galon J, Bausinger H, Spehner D, Bohbot A, Cohen J, Cazenave JP, Fridman WH, Sautès C, Hanau D.

Adv Exp Med Biol. 1997;417:345-52.

PMID:
9286384
43.

Examination of cutaneous macroglobulinosis by immunoelectron microscopy.

Lipsker D, Cribier B, Spehner D, Boehm N, Heid E, Grosshans E.

Br J Dermatol. 1996 Aug;135(2):287-91.

PMID:
8881676
44.

A vaccinia virus transfer vector using a GUS reporter gene inserted into the I4L locus.

Howley PM, Spehner D, Drillien R.

Gene. 1996 Jun 26;172(2):233-7.

PMID:
8682309
45.

Role of B cell receptor Ig alpha and Ig beta subunits in MHC class II-restricted antigen presentation.

Bonnerot C, Lankar D, Hanau D, Spehner D, Davoust J, Salamero J, Fridman WH.

Immunity. 1995 Sep;3(3):335-47.

46.
47.

Localization of viral protein X in simian immunodeficiency virus macaque strain and analysis of its packaging requirements.

Liska V, Spehner D, Mehtali M, Schmitt D, Kirn A, Aubertin AM.

J Gen Virol. 1994 Nov;75 ( Pt 11):2955-62.

PMID:
7964605
48.
49.

Recombinant MUC 1 vaccinia virus: a potential vector for immunotherapy of breast cancer.

Balloul JM, Acres RB, Geist M, Dott K, Stefani L, Schmitt D, Drillien R, Spehner D, McKenzie I, Xing PX, et al.

Cell Mol Biol (Noisy-le-grand). 1994;40 Suppl 1:49-59.

PMID:
7950862
50.

The conserved N-terminal region of Sendai virus nucleocapsid protein NP is required for nucleocapsid assembly.

Buchholz CJ, Spehner D, Drillien R, Neubert WJ, Homann HE.

J Virol. 1993 Oct;67(10):5803-12.

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