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Items: 45


Bone marrow-derived mesenchymal stem cells inhibit vascular smooth muscle cell proliferation and neointimal hyperplasia after arterial injury in rats.

Iso Y, Usui S, Toyoda M, Spees JL, Umezawa A, Suzuki H.

Biochem Biophys Rep. 2018 Oct 24;16:79-87. doi: 10.1016/j.bbrep.2018.10.001. eCollection 2018 Dec.


Harnessing Epicardial Progenitor Cells and Their Derivatives for Rescue and Repair of Cardiac Tissue After Myocardial Infarction.

Rao KS, Spees JL.

Curr Mol Biol Rep. 2017 Sep;3(3):149-158. doi: 10.1007/s40610-017-0066-6. Epub 2017 Jul 15.


Mechanisms of mesenchymal stem/stromal cell function.

Spees JL, Lee RH, Gregory CA.

Stem Cell Res Ther. 2016 Aug 31;7(1):125. doi: 10.1186/s13287-016-0363-7. Review.


Priming with erythropoietin enhances cell survival and angiogenic effect of mesenchymal stem cell implantation in rat limb ischemia.

Mizukami T, Iso Y, Sato C, Sasai M, Spees JL, Toyoda M, Umezawa A, Miyazaki A, Suzuki H.

Regen Ther. 2016 Feb 13;4:1-8. doi: 10.1016/j.reth.2016.01.004. eCollection 2016 Jun.


Notch1-STAT3-ETBR signaling in brain injury and cancer.

LeComte MD, Spees JL.

Cytokine. 2016 Apr;80:64-5. doi: 10.1016/j.cyto.2015.08.259. Epub 2015 Aug 25. No abstract available.


Notch1-STAT3-ETBR signaling axis controls reactive astrocyte proliferation after brain injury.

LeComte MD, Shimada IS, Sherwin C, Spees JL.

Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8726-31. doi: 10.1073/pnas.1501029112. Epub 2015 Jun 29.


Human epicardial cell-conditioned medium contains HGF/IgG complexes that phosphorylate RYK and protect against vascular injury.

Rao KS, Aronshtam A, McElory-Yaggy KL, Bakondi B, VanBuren P, Sobel BE, Spees JL.

Cardiovasc Res. 2015 Jul 15;107(2):277-86. doi: 10.1093/cvr/cvv168. Epub 2015 May 29.


Osteogenic differentiation of human mesenchymal stem cells through alginate-graft-poly(ethylene glycol) microsphere-mediated intracellular growth factor delivery.

Miao T, Rao KS, Spees JL, Oldinski RA.

J Control Release. 2014 Oct 28;192:57-66. doi: 10.1016/j.jconrel.2014.06.029. Epub 2014 Jun 28.


Priming with ligands secreted by human stromal progenitor cells promotes grafts of cardiac stem/progenitor cells after myocardial infarction.

Iso Y, Rao KS, Poole CN, Zaman AK, Curril I, Sobel BE, Kajstura J, Anversa P, Spees JL.

Stem Cells. 2014 Mar;32(3):674-83. doi: 10.1002/stem.1546.


Triacetin-based acetate supplementation as a chemotherapeutic adjuvant therapy in glioma.

Tsen AR, Long PM, Driscoll HE, Davies MT, Teasdale BA, Penar PL, Pendlebury WW, Spees JL, Lawler SE, Viapiano MS, Jaworski DM.

Int J Cancer. 2014 Mar 15;134(6):1300-10. doi: 10.1002/ijc.28465. Epub 2013 Sep 30.


Correction: Pre-Treatment with Amifostine Protects against Cyclophosphamide-Induced Disruption of Taste in Mice.

Mukherjee N, Carroll BL, Spees JL, Delay ER.

PLoS One. 2013 Jul 31;8(7). doi: 10.1371/annotation/5487e265-8175-47cb-b9a4-d85862a4a96f. eCollection 2013.


Pre-treatment with amifostine protects against cyclophosphamide-induced disruption of taste in mice.

Mukherjee N, Carroll BL, Spees JL, Delay ER.

PLoS One. 2013 Apr 23;8(4):e61607. doi: 10.1371/journal.pone.0061607. Print 2013. Erratum in: PLoS One. 2013 Jul 31;8(7):null.


Attenuation of cardiac vascular rhexis: a promising therapeutic target.

Tarikuz Zaman AK, Spees JL, Sobel BE.

Coron Artery Dis. 2013 May;24(3):245-52. doi: 10.1097/MCA.0b013e32835d6688.


Distinct mobilization of circulating CD271+ mesenchymal progenitors from hematopoietic progenitors during aging and after myocardial infarction.

Iso Y, Yamaya S, Sato T, Poole CN, Isoyama K, Mimura M, Koba S, Kobayashi Y, Takeyama Y, Spees JL, Suzuki H.

Stem Cells Transl Med. 2012 Jun;1(6):462-8. doi: 10.5966/sctm.2011-0051. Epub 2012 Jun 5.


Self-renewal and differentiation of reactive astrocyte-derived neural stem/progenitor cells isolated from the cortical peri-infarct area after stroke.

Shimada IS, LeComte MD, Granger JC, Quinlan NJ, Spees JL.

J Neurosci. 2012 Jun 6;32(23):7926-40. doi: 10.1523/JNEUROSCI.4303-11.2012.


Multipotent stromal cell therapy for cavernous nerve injury-induced erectile dysfunction.

Albersen M, Kendirci M, Van der Aa F, Hellstrom WJ, Lue TF, Spees JL.

J Sex Med. 2012 Feb;9(2):385-403. doi: 10.1111/j.1743-6109.2011.02556.x. Epub 2011 Dec 6. Review.


Proliferating reactive astrocytes are regulated by Notch-1 in the peri-infarct area after stroke.

Shimada IS, Borders A, Aronshtam A, Spees JL.

Stroke. 2011 Nov;42(11):3231-7. doi: 10.1161/STROKEAHA.111.623280. Epub 2011 Aug 11.


Vascular rhexis in mice subjected to non-sustained myocardial ischemia and its therapeutic implications.

Zaman AK, French CJ, Spees JL, Binbrek AS, Sobel BE.

Exp Biol Med (Maywood). 2011 May 1;236(5):598-603. doi: 10.1258/ebm.2011.011026. Epub 2011 Apr 26.


SDF-1α secreted by human CD133-derived multipotent stromal cells promotes neural progenitor cell survival through CXCR7.

Bakondi B, Shimada IS, Peterson BM, Spees JL.

Stem Cells Dev. 2011 Jun;20(6):1021-9. doi: 10.1089/scd.2010.0198. Epub 2010 Nov 9.


Transplantation of nonhematopoietic adult bone marrow stem/progenitor cells isolated by p75 nerve growth factor receptor into the penis rescues erectile function in a rat model of cavernous nerve injury.

Kendirci M, Trost L, Bakondi B, Whitney MJ, Hellstrom WJ, Spees JL.

J Urol. 2010 Oct;184(4):1560-6. doi: 10.1016/j.juro.2010.05.088. Epub 2010 Aug 21.


Incomplete reprogramming after fusion of human multipotent stromal cells and bronchial epithelial cells.

Curril IM, Koide M, Yang CH, Segal A, Wellman GC, Spees JL.

FASEB J. 2010 Dec;24(12):4856-64. doi: 10.1096/fj.09-152991. Epub 2010 Aug 19.


Human CD133-derived bone marrow stromal cells establish ectopic hematopoietic microenvironments in immunodeficient mice.

Bakondi B, Spees JL.

Biochem Biophys Res Commun. 2010 Sep 17;400(2):212-8. doi: 10.1016/j.bbrc.2010.08.040. Epub 2010 Aug 16.


Isolation of locally derived stem/progenitor cells from the peri-infarct area that do not migrate from the lateral ventricle after cortical stroke.

Shimada IS, Peterson BM, Spees JL.

Stroke. 2010 Sep;41(9):e552-60. doi: 10.1161/STROKEAHA.110.589010. Epub 2010 Jul 29.


Vascular rhexis: loss of integrity of coronary vasculature in mice subjected to myocardial infarction.

French CJ, Zaman AK, Kelm RJ Jr, Spees JL, Sobel BE.

Exp Biol Med (Maywood). 2010 Aug;235(8):966-73. doi: 10.1258/ebm.2010.010108.


Targeted gene addition to human mesenchymal stromal cells as a cell-based plasma-soluble protein delivery platform.

Benabdallah BF, Allard E, Yao S, Friedman G, Gregory PD, Eliopoulos N, Fradette J, Spees JL, Haddad E, Holmes MC, Beauséjour CM.

Cytotherapy. 2010 May;12(3):394-9. doi: 10.3109/14653240903583803.


CD133 identifies a human bone marrow stem/progenitor cell sub-population with a repertoire of secreted factors that protect against stroke.

Bakondi B, Shimada IS, Perry A, Munoz JR, Ylostalo J, Howard AB, Gregory CA, Spees JL.

Mol Ther. 2009 Nov;17(11):1938-47. doi: 10.1038/mt.2009.185. Epub 2009 Aug 18.


The magnitude and temporal dependence of apoptosis early after myocardial ischemia with or without reperfusion.

French CJ, Spees JL, Zaman AK, Taatjes DJ, Sobel BE.

FASEB J. 2009 Apr;23(4):1177-85. doi: 10.1096/fj.08-116509. Epub 2008 Dec 18.


Derivation of lung epithelium from human cord blood-derived mesenchymal stem cells.

Sueblinvong V, Loi R, Eisenhauer PL, Bernstein IM, Suratt BT, Spees JL, Weiss DJ.

Am J Respir Crit Care Med. 2008 Apr 1;177(7):701-11. Epub 2007 Dec 6.


Bone marrow progenitor cells contribute to repair and remodeling of the lung and heart in a rat model of progressive pulmonary hypertension.

Spees JL, Whitney MJ, Sullivan DE, Lasky JA, Laboy M, Ylostalo J, Prockop DJ.

FASEB J. 2008 Apr;22(4):1226-36. Epub 2007 Nov 21.


Engraftment of bone marrow progenitor cells in a rat model of asbestos-induced pulmonary fibrosis.

Spees JL, Pociask DA, Sullivan DE, Whitney MJ, Lasky JA, Prockop DJ, Brody AR.

Am J Respir Crit Care Med. 2007 Aug 15;176(4):385-94. Epub 2007 May 11.


Multipotent human stromal cells improve cardiac function after myocardial infarction in mice without long-term engraftment.

Iso Y, Spees JL, Serrano C, Bakondi B, Pochampally R, Song YH, Sobel BE, Delafontaine P, Prockop DJ.

Biochem Biophys Res Commun. 2007 Mar 16;354(3):700-6. Epub 2007 Jan 17.


Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/scid mice.

Lee RH, Seo MJ, Reger RL, Spees JL, Pulin AA, Olson SD, Prockop DJ.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17438-43. Epub 2006 Nov 6.


Mitochondrial transfer between cells can rescue aerobic respiration.

Spees JL, Olson SD, Whitney MJ, Prockop DJ.

Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1283-8. Epub 2006 Jan 23.


Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice.

Munoz JR, Stoutenger BR, Robinson AP, Spees JL, Prockop DJ.

Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18171-6. Epub 2005 Dec 5. Erratum in: Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):2000-2.


How Wnt signaling affects bone repair by mesenchymal stem cells from the bone marrow.

Gregory CA, Gunn WG, Reyes E, Smolarz AJ, Munoz J, Spees JL, Prockop DJ.

Ann N Y Acad Sci. 2005 May;1049:97-106. Review.


Non-hematopoietic bone marrow stem cells: molecular control of expansion and differentiation.

Gregory CA, Prockop DJ, Spees JL.

Exp Cell Res. 2005 Jun 10;306(2):330-5. Epub 2005 Apr 15. Review.


Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis.

Wang G, Bunnell BA, Painter RG, Quiniones BC, Tom S, Lanson NA Jr, Spees JL, Bertucci D, Peister A, Weiss DJ, Valentine VG, Prockop DJ, Kolls JK.

Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):186-91. Epub 2004 Dec 22.


Internalized antigens must be removed to prepare hypoimmunogenic mesenchymal stem cells for cell and gene therapy.

Spees JL, Gregory CA, Singh H, Tucker HA, Peister A, Lynch PJ, Hsu SC, Smith J, Prockop DJ.

Mol Ther. 2004 May;9(5):747-56.


Molt cycle-dependent molecular chaperone and polyubiquitin gene expression in lobster.

Spees JL, Chang SA, Mykles DL, Snyder MJ, Chang ES.

Cell Stress Chaperones. 2003 Fall;8(3):258-64.


One strategy for cell and gene therapy: harnessing the power of adult stem cells to repair tissues.

Prockop DJ, Gregory CA, Spees JL.

Proc Natl Acad Sci U S A. 2003 Sep 30;100 Suppl 1:11917-23. Epub 2003 Sep 17. Review.


Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma.

Spees JL, Olson SD, Ylostalo J, Lynch PJ, Smith J, Perry A, Peister A, Wang MY, Prockop DJ.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2397-402. Epub 2003 Feb 26.


Osmotic induction of stress-responsive gene expression in the lobster Homarus americanus.

Spees JL, Chang SA, Snyder MJ, Chang ES.

Biol Bull. 2002 Dec;203(3):331-7.


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