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Items: 1 to 50 of 126

1.
2.

Human Cytomegalovirus Replication Is Inhibited by the Autophagy-Inducing Compounds Trehalose and SMER28 through Distinctively Different Mechanisms.

Clark AE, Sabalza M, Gordts PLSM, Spector DH.

J Virol. 2018 Feb 26;92(6). pii: e02015-17. doi: 10.1128/JVI.02015-17. Print 2018 Mar 15.

3.

RNA-binding protein CPEB1 remodels host and viral RNA landscapes.

Batra R, Stark TJ, Clark E, Belzile JP, Wheeler EC, Yee BA, Huang H, Gelboin-Burkhart C, Huelga SC, Aigner S, Roberts BT, Bos TJ, Sathe S, Donohue JP, Rigo F, Ares M Jr, Spector DH, Yeo GW.

Nat Struct Mol Biol. 2016 Dec;23(12):1101-1110. doi: 10.1038/nsmb.3310. Epub 2016 Oct 24.

4.

Trehalose, an mTOR-Independent Inducer of Autophagy, Inhibits Human Cytomegalovirus Infection in Multiple Cell Types.

Belzile JP, Sabalza M, Craig M, Clark E, Morello CS, Spector DH.

J Virol. 2015 Nov 11;90(3):1259-77. doi: 10.1128/JVI.02651-15. Print 2016 Feb 1.

6.

Human cytomegalovirus riding the cell cycle.

Spector DH.

Med Microbiol Immunol. 2015 Jun;204(3):409-19. doi: 10.1007/s00430-015-0396-z. Epub 2015 Mar 17. Review.

PMID:
25776080
7.

IUGR and congenital cytomegalovirus infection.

Spector DH.

J Infect Dis. 2014 May 15;209(10):1497-9. doi: 10.1093/infdis/jiu092. Epub 2014 Feb 12. No abstract available.

PMID:
24526739
8.
9.

25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages.

Shibata N, Carlin AF, Spann NJ, Saijo K, Morello CS, McDonald JG, Romanoski CE, Maurya MR, Kaikkonen MU, Lam MT, Crotti A, Reichart D, Fox JN, Quehenberger O, Raetz CR, Sullards MC, Murphy RC, Merrill AH Jr, Brown HA, Dennis EA, Fahy E, Subramaniam S, Cavener DR, Spector DH, Russell DW, Glass CK.

J Biol Chem. 2013 Dec 13;288(50):35812-23. doi: 10.1074/jbc.M113.519637. Epub 2013 Nov 4.

11.

Inactivated HSV-2 in MPL/alum adjuvant provides nearly complete protection against genital infection and shedding following long term challenge and rechallenge.

Morello CS, Kraynyak KA, Levinson MS, Chen Z, Lee KF, Spector DH.

Vaccine. 2012 Oct 12;30(46):6541-6550. doi: 10.1016/j.vaccine.2012.08.049. Epub 2012 Sep 1.

12.

A mutation deleting sequences encoding the amino terminus of human cytomegalovirus UL84 impairs interaction with UL44 and capsid localization.

Strang BL, Bender BJ, Sharma M, Pesola JM, Sanders RL, Spector DH, Coen DM.

J Virol. 2012 Oct;86(20):11066-77. Epub 2012 Aug 1.

13.

High-resolution profiling and analysis of viral and host small RNAs during human cytomegalovirus infection.

Stark TJ, Arnold JD, Spector DH, Yeo GW.

J Virol. 2012 Jan;86(1):226-35. doi: 10.1128/JVI.05903-11. Epub 2011 Oct 19.

14.
15.

Early viral gene expression and function.

White EA, Spector DH.

In: Arvin A, Campadelli-Fiume G, Mocarski E, Moore PS, Roizman B, Whitley R, Yamanishi K, editors. Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Cambridge: Cambridge University Press; 2007. Chapter 18.

16.

Immunization with herpes simplex virus 2 (HSV-2) genes plus inactivated HSV-2 is highly protective against acute and recurrent HSV-2 disease.

Morello CS, Levinson MS, Kraynyak KA, Spector DH.

J Virol. 2011 Apr;85(7):3461-72. doi: 10.1128/JVI.02521-10. Epub 2011 Jan 26.

18.
19.

Proteasome subunits relocalize during human cytomegalovirus infection, and proteasome activity is necessary for efficient viral gene transcription.

Tran K, Mahr JA, Spector DH.

J Virol. 2010 Mar;84(6):3079-93. doi: 10.1128/JVI.02236-09. Epub 2009 Dec 30.

20.
22.

Subversion of cell cycle regulatory pathways.

Sanchez V, Spector DH.

Curr Top Microbiol Immunol. 2008;325:243-62. Review.

PMID:
18637510
24.

A human cytomegalovirus-encoded microRNA regulates expression of multiple viral genes involved in replication.

Grey F, Meyers H, White EA, Spector DH, Nelson J.

PLoS Pathog. 2007 Nov;3(11):e163.

27.

Nuclear export of the human cytomegalovirus tegument protein pp65 requires cyclin-dependent kinase activity and the Crm1 exporter.

Sanchez V, Mahr JA, Orazio NI, Spector DH.

J Virol. 2007 Nov;81(21):11730-6. Epub 2007 Aug 22.

32.

Genome-wide analysis reveals a highly diverse CD8 T cell response to murine cytomegalovirus.

Munks MW, Gold MC, Zajac AL, Doom CM, Morello CS, Spector DH, Hill AB.

J Immunol. 2006 Mar 15;176(6):3760-6.

39.
41.

Viral induction of site-specific chromosome damage.

Fortunato EA, Spector DH.

Rev Med Virol. 2003 Jan-Feb;13(1):21-37. Review.

PMID:
12516060
42.

Virology. CMV makes a timely exit.

Sanchez V, Spector DH.

Science. 2002 Aug 2;297(5582):778-9. No abstract available.

PMID:
12161637
45.
47.
50.

Exploitation of cellular signaling and regulatory pathways by human cytomegalovirus.

Fortunato EA, McElroy AK, Sanchez I, Spector DH.

Trends Microbiol. 2000 Mar;8(3):111-9. Review.

PMID:
10707064

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