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Items: 1 to 50 of 171

1.

Bronchoalveolar lavage cytokines are of minor value to diagnose complications following lung transplantation.

Speck NE, Probst-Müller E, Haile SR, Benden C, Kohler M, Huber LC, Robinson CA.

Cytokine. 2019 Aug 7;125:154794. doi: 10.1016/j.cyto.2019.154794. [Epub ahead of print]

PMID:
31400641
2.

Macrophages Fertilize the Soil to Promote Hematopoietic Cell Growth.

Bennett L, Mumau M, Speck NA.

Immunity. 2019 Jun 18;50(6):1342-1344. doi: 10.1016/j.immuni.2019.05.017.

PMID:
31216456
3.

Case Report: Treatment for Rectovaginal Fistula in Crohn's Disease Using Fractionate CO2 Vaginal Laser with Anti-TNF Therapy.

Drumond DG, Chebli JMF, Speck NMG, Chebli LA, Pannain GD, Esperança SD, Condé CMS.

Photobiomodul Photomed Laser Surg. 2019 Jul;37(7):451-454. doi: 10.1089/photob.2019.4643. Epub 2019 Jun 17.

PMID:
31210577
4.

RUNX1 and the endothelial origin of blood.

Gao L, Tober J, Gao P, Chen C, Tan K, Speck NA.

Exp Hematol. 2018 Dec;68:2-9. doi: 10.1016/j.exphem.2018.10.009. Epub 2018 Oct 31. Review.

5.

A Western Blotting Protocol for Small Numbers of Hematopoietic Stem Cells.

Cai X, Zheng Y, Speck NA.

J Vis Exp. 2018 Aug 22;(138). doi: 10.3791/56855.

6.

Runx1 is sufficient for blood cell formation from non-hemogenic endothelial cells in vivo only during early embryogenesis.

Yzaguirre AD, Howell ED, Li Y, Liu Z, Speck NA.

Development. 2018 Jan 29;145(2). pii: dev158162. doi: 10.1242/dev.158162.

7.

Therapeutic Assessment of Vulvar Squamous Intraepithelial Lesions with CO2 Laser Vaporization in Immunosuppressed Patients.

Ribalta JCL, Mateussi MV, Speck NMG.

Rev Bras Ginecol Obstet. 2018 Jan;40(1):26-31. doi: 10.1055/s-0037-1618573. Epub 2018 Jan 16.

8.

RUNX1 Mutations in Inherited and Sporadic Leukemia.

Bellissimo DC, Speck NA.

Front Cell Dev Biol. 2017 Dec 20;5:111. doi: 10.3389/fcell.2017.00111. eCollection 2017. Review.

9.

Twist1 regulates embryonic hematopoietic differentiation through binding to Myb and Gata2 promoter regions.

Kulkeaw K, Inoue T, Iino T, Tani K, Akashi K, Speck NA, Nakanishi Y, Sugiyama D.

Blood Adv. 2017 Aug 31;1(20):1672-1681. doi: 10.1182/bloodadvances.2017006056. eCollection 2017 Sep 12.

10.

Maturation of hematopoietic stem cells from prehematopoietic stem cells is accompanied by up-regulation of PD-L1.

Tober J, Maijenburg MMW, Li Y, Gao L, Hadland BK, Gao P, Minoura K, Bernstein ID, Tan K, Speck NA.

J Exp Med. 2018 Feb 5;215(2):645-659. doi: 10.1084/jem.20161594. Epub 2017 Dec 27.

11.

A tool compound targeting the core binding factor Runt domain to disrupt binding to CBFβ in leukemic cells.

Oo ZM, Illendula A, Grembecka J, Schmidt C, Zhou Y, Esain V, Kwan W, Frost I, North TE, Rajewski RA, Speck NA, Bushweller JH.

Leuk Lymphoma. 2018 Sep;59(9):2188-2200. doi: 10.1080/10428194.2017.1410882. Epub 2017 Dec 18.

12.

Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11.

Zhen T, Kwon EM, Zhao L, Hsu J, Hyde RK, Lu Y, Alemu L, Speck NA, Liu PP.

Blood. 2017 Nov 30;130(22):2431-2442. doi: 10.1182/blood-2017-04-780106. Epub 2017 Oct 10.

13.

Plasma and bronchoalveolar lavage samples in acute lung allograft rejection: the potential role of cytokines as diagnostic markers.

Speck NE, Schuurmans MM, Benden C, Robinson CA, Huber LC.

Respir Res. 2017 Aug 7;18(1):151. doi: 10.1186/s12931-017-0634-6. Review.

14.

CD27 marks murine embryonic hematopoietic stem cells and type II prehematopoietic stem cells.

Li Y, Gao L, Hadland B, Tan K, Speck NA.

Blood. 2017 Jul 20;130(3):372-376. doi: 10.1182/blood-2017-03-776849. Epub 2017 Jun 6. No abstract available.

15.

Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression.

Kim E, Cheng Y, Bolton-Gillespie E, Cai X, Ma C, Tarangelo A, Le L, Jambhekar M, Raman P, Hayer KE, Wertheim G, Speck NA, Tong W, Viatour P.

J Exp Med. 2017 Jul 3;214(7):1901-1912. doi: 10.1084/jem.20160719. Epub 2017 May 26.

16.

Conversion of adult endothelium to immunocompetent haematopoietic stem cells.

Lis R, Karrasch CC, Poulos MG, Kunar B, Redmond D, Duran JGB, Badwe CR, Schachterle W, Ginsberg M, Xiang J, Tabrizi AR, Shido K, Rosenwaks Z, Elemento O, Speck NA, Butler JM, Scandura JM, Rafii S.

Nature. 2017 May 25;545(7655):439-445. doi: 10.1038/nature22326. Epub 2017 May 17.

17.

Association between the p53 arginine/arginine homozygous genotype at codon 72 and human papillomavirus E6/E7 mRNA expression.

Chuery ACS, Silva IDCGD, Ribalta JCL, Speck NMG.

Braz J Infect Dis. 2017 May - Jun;21(3):248-254. doi: 10.1016/j.bjid.2017.03.002. Epub 2017 Mar 25.

18.

The Role of Runx1 in Embryonic Blood Cell Formation.

Yzaguirre AD, de Bruijn MF, Speck NA.

Adv Exp Med Biol. 2017;962:47-64. doi: 10.1007/978-981-10-3233-2_4. Review.

19.

HPV genotyping and p16 expression in Xingu Indigenous Park, Brazil.

Freitas VG, Focchi GR, Pereira ER, Levi JE, Speck NM, Ribalta JC.

Genet Mol Res. 2016 Sep 16;15(3). doi: 10.4238/gmr.15036840.

PMID:
27706717
20.

Stress Can Be a Good Thing for Blood Formation.

Speck NA.

Cell Stem Cell. 2016 Sep 1;19(3):279-80. doi: 10.1016/j.stem.2016.08.011.

21.

Insights into blood cell formation from hemogenic endothelium in lesser-known anatomic sites.

Yzaguirre AD, Speck NA.

Dev Dyn. 2016 Oct;245(10):1011-28. doi: 10.1002/dvdy.24430. Epub 2016 Aug 17.

22.

Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology.

Speck NE, Schuurmans MM, Murer C, Benden C, Huber LC.

Respir Res. 2016 Jun 21;17(1):74. doi: 10.1186/s12931-016-0391-y. Review.

23.

Taking the Leap: Runx1 in the Formation of Blood from Endothelium.

Tober J, Maijenburg MW, Speck NA.

Curr Top Dev Biol. 2016;118:113-62. doi: 10.1016/bs.ctdb.2016.01.008. Epub 2016 Feb 18. Review.

PMID:
27137656
24.

Extravascular endothelial and hematopoietic islands form through multiple pathways in midgestation mouse embryos.

Yzaguirre AD, Speck NA.

Dev Biol. 2016 Jul 1;415(1):111-121. doi: 10.1016/j.ydbio.2016.04.004. Epub 2016 Apr 20.

25.

Treatment of Bartholin gland cyst with CO2laser.

Speck NM, Boechat KP, Santos GM, Ribalta JC.

Einstein (Sao Paulo). 2016 Jan-Mar;14(1):25-9. doi: 10.1590/S1679-45082016AO3568. English, Portuguese.

26.

Expression of human papillomavirus E6 and E7 oncoprotein mRNA in women with low-grade squamous intraepithelial lesions or less.

Casagrande DC, Ribalta JC, Leite KD, Schimidt M, Speck NM.

Genet Mol Res. 2016 Mar 31;15(1). doi: 10.4238/gmr.15017916.

27.

Immunoexpression of HPV 16/18 E6 and E7 oncoproteins in high-grade cervical squamous intraepithelial lesions in HIV-positive women.

Rodrigues LC, Speck NM, Focchi GR, Schimidt MA, Marques RM, Ribalta JC.

Genet Mol Res. 2016 Feb 19;15(1). doi: 10.4238/gmr.15017220.

28.

HPV infection-associated anogenital cyto-colpo-histological findings and molecular typing in HIV-positive women.

Tso FK, Rodrigues CL, Levi JE, Mattosinho de Castro Ferraz MG, Speck NM, Ribalta JC.

Genet Mol Res. 2015 Dec 21;14(4):17630-40. doi: 10.4238/2015.December.21.36.

29.

A Medical Student-Driven "Vaccine Blitz" at a School-Based Health Center as an Effective Way to Improve Adolescent Vaccination Rates.

Eldred SV, Hamid HS, Snider JC, Weinberg SH, Speck N, Reed BD, Riley M.

Fam Med. 2015 Jul-Aug;47(7):546-8.

PMID:
26562643
30.

An interesting finding in the uterine cervix: Schistosoma hematobium calcified eggs.

Toller A, Scopin AC, Apfel V, Prigenzi KC, Tso FK, Focchi GR, Speck N, Ribalta J.

Autops Case Rep. 2015 Jun 30;5(2):41-4. doi: 10.4322/acr.2015.003. eCollection 2015 Apr-Jun.

31.

Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos.

Yzaguirre AD, Padmanabhan A, de Groh ED, Engleka KA, Li J, Speck NA, Epstein JA.

Elife. 2015 Oct 13;4:e07780. doi: 10.7554/eLife.07780.

32.

Prevention, diagnosis and treatment of cervical cancer precursor lesions at the Xingu Indigenous Park, Brazil.

Pereira ER, Speck NM, Rodrigues DA, De Freitas VG, Ribalta JC.

Eur J Gynaecol Oncol. 2015;36(4):376-82.

PMID:
26390686
33.

[Prevalence of cytological atypia and high-risk human papillomavirus infection in Panará indigenous women in Central Brazil].

Rodrigues DA, Pereira ÉR, Oliveira LS, Speck NM, Gimeno SG.

Cad Saude Publica. 2014 Dec;30(12):2587-93. doi: 10.1590/0102-31l'1X00152713. Portuguese.

34.

Runx1 Deficiency Decreases Ribosome Biogenesis and Confers Stress Resistance to Hematopoietic Stem and Progenitor Cells.

Cai X, Gao L, Teng L, Ge J, Oo ZM, Kumar AR, Gilliland DG, Mason PJ, Tan K, Speck NA.

Cell Stem Cell. 2015 Aug 6;17(2):165-77. doi: 10.1016/j.stem.2015.06.002. Epub 2015 Jul 9.

35.

Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.

Ohta Y, Okabe T, Larmour C, Di Rocco A, Maijenburg MW, Phillips A, Speck NA, Wakitani S, Nakamura T, Yamada Y, Enomoto-Iwamoto M, Pacifici M, Iwamoto M.

Arthritis Rheumatol. 2015 Oct;67(10):2679-90. doi: 10.1002/art.39243.

36.

Cervical cancer screening in young and elderly women of the Xingu Indigenous Park: evaluation of the recommended screening age group in Brazil.

Speck NM, Pinheiro Jda S, Pereira ER, Rodrigues D, Focchi GR, Ribalta JC.

Einstein (Sao Paulo). 2015 Jan-Mar;13(1):52-7. doi: 10.1590/S1679-45082015AO3222. English, Portuguese.

37.

The Antiatherogenic Effect of Fish Oil in Male Mice Is Associated with a Diminished Release of Endothelial ADAM17 and ADAM10 Substrates.

Speck N, Brandsch C, Schmidt N, Yazdekhasti N, Hirche F, Lucius R, Rimbach G, Stangl GI, Reiss K.

J Nutr. 2015 Jun;145(6):1218-26. doi: 10.3945/jn.115.211375. Epub 2015 Apr 29.

PMID:
25926412
38.

Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages.

Ditadi A, Sturgeon CM, Tober J, Awong G, Kennedy M, Yzaguirre AD, Azzola L, Ng ES, Stanley EG, French DL, Cheng X, Gadue P, Speck NA, Elefanty AG, Keller G.

Nat Cell Biol. 2015 May;17(5):580-91. doi: 10.1038/ncb3161. Epub 2015 Apr 27.

39.

The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding.

Maretzky T, Evers A, Le Gall S, Alabi RO, Speck N, Reiss K, Blobel CP.

J Biol Chem. 2015 Mar 20;290(12):7416-25. doi: 10.1074/jbc.M114.603753. Epub 2015 Jan 20.

40.

Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche.

Tamplin OJ, Durand EM, Carr LA, Childs SJ, Hagedorn EJ, Li P, Yzaguirre AD, Speck NA, Zon LI.

Cell. 2015 Jan 15;160(1-2):241-52. doi: 10.1016/j.cell.2014.12.032.

41.

Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production.

Li Y, Esain V, Teng L, Xu J, Kwan W, Frost IM, Yzaguirre AD, Cai X, Cortes M, Maijenburg MW, Tober J, Dzierzak E, Orkin SH, Tan K, North TE, Speck NA.

Genes Dev. 2014 Dec 1;28(23):2597-612. doi: 10.1101/gad.253302.114. Epub 2014 Nov 13.

42.

Runx1 and Cbfβ regulate the development of Flt3+ dendritic cell progenitors and restrict myeloproliferative disorder.

Satpathy AT, Briseño CG, Cai X, Michael DG, Chou C, Hsiung S, Bhattacharya D, Speck NA, Egawa T.

Blood. 2014 May 8;123(19):2968-77. doi: 10.1182/blood-2013-11-539643. Epub 2014 Mar 27.

43.

The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells.

Gerhardt DM, Pajcini KV, D'altri T, Tu L, Jain R, Xu L, Chen MJ, Rentschler S, Shestova O, Wertheim GB, Tobias JW, Kluk M, Wood AW, Aster JC, Gimotty PA, Epstein JA, Speck N, Bigas A, Pear WS.

Genes Dev. 2014 Mar 15;28(6):576-93. doi: 10.1101/gad.227496.113.

44.

Biochanin A and prunetin improve epithelial barrier function in intestinal CaCo-2 cells via downregulation of ERK, NF-κB, and tyrosine phosphorylation.

Piegholdt S, Pallauf K, Esatbeyoglu T, Speck N, Reiss K, Ruddigkeit L, Stocker A, Huebbe P, Rimbach G.

Free Radic Biol Med. 2014 May;70:255-64. doi: 10.1016/j.freeradbiomed.2014.02.025. Epub 2014 Mar 12.

PMID:
24631489
45.

Gata2 is required for HSC generation and survival.

de Pater E, Kaimakis P, Vink CS, Yokomizo T, Yamada-Inagawa T, van der Linden R, Kartalaei PS, Camper SA, Speck N, Dzierzak E.

J Exp Med. 2013 Dec 16;210(13):2843-50. doi: 10.1084/jem.20130751. Epub 2013 Dec 2.

46.

HIF1α is a regulator of hematopoietic progenitor and stem cell development in hypoxic sites of the mouse embryo.

Imanirad P, Solaimani Kartalaei P, Crisan M, Vink C, Yamada-Inagawa T, de Pater E, Kurek D, Kaimakis P, van der Linden R, Speck N, Dzierzak E.

Stem Cell Res. 2014 Jan;12(1):24-35. doi: 10.1016/j.scr.2013.09.006. Epub 2013 Oct 2.

47.

Accuracy of the cytopathology, bacterioscopy, and vaginal flora culture.

Almeida PQ, Pereira MA, Palomo FS, Okazaki C, Schimidt MA, Speck NM, Ribalta JC.

Clin Exp Obstet Gynecol. 2013;40(2):243-5.

PMID:
23971250
48.

Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells.

Tober J, Yzaguirre AD, Piwarzyk E, Speck NA.

Development. 2013 Sep;140(18):3765-76. doi: 10.1242/dev.094961. Epub 2013 Aug 7.

49.

The expression of Sox17 identifies and regulates haemogenic endothelium.

Clarke RL, Yzaguirre AD, Yashiro-Ohtani Y, Bondue A, Blanpain C, Pear WS, Speck NA, Keller G.

Nat Cell Biol. 2013 May;15(5):502-10. doi: 10.1038/ncb2724. Epub 2013 Apr 21.

50.

Depth of glandular crypts and its involvement in squamous intraepithelial cervical neoplasia submitted to large loop excision of transformation zone (LLETZ).

Okazaki C, Focchi GR, Taha NS, Almeida PQ, Schimidt MA, Speck NM, Ribalta JC.

Eur J Gynaecol Oncol. 2013;34(1):48-50.

PMID:
23590000

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