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Items: 8


SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function.

Matt L, Kirk LM, Chenaux G, Speca DJ, Puhger KR, Pride MC, Qneibi M, Haham T, Plambeck KE, Stern-Bach Y, Silverman JL, Crawley JN, Hell JW, Díaz E.

Cell Rep. 2018 Feb 27;22(9):2246-2253. doi: 10.1016/j.celrep.2018.02.026.


Whole exome sequencing reveals a functional mutation in the GAIN domain of the Bai2 receptor underlying a forward mutagenesis hyperactivity QTL.

Speca DJ, Trimmer JS, Peterson AS, Díaz E.

Mamm Genome. 2017 Dec;28(11-12):465-475. doi: 10.1007/s00335-017-9716-5. Epub 2017 Sep 12.


Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo.

Chenaux G, Matt L, Hill TC, Kaur I, Liu XB, Kirk LM, Speca DJ, McMahon SA, Zito K, Hell JW, Díaz E.

eNeuro. 2016 Oct 21;3(5). pii: ENEURO.0130-16.2016. eCollection 2016 Sep-Oct.


A novel epileptic encephalopathy mutation in KCNB1 disrupts Kv2.1 ion selectivity, expression, and localization.

Thiffault I, Speca DJ, Austin DC, Cobb MM, Eum KS, Safina NP, Grote L, Farrow EG, Miller N, Soden S, Kingsmore SF, Trimmer JS, Saunders CJ, Sack JT.

J Gen Physiol. 2015 Nov;146(5):399-410. doi: 10.1085/jgp.201511444.


Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability.

Speca DJ, Ogata G, Mandikian D, Bishop HI, Wiler SW, Eum K, Wenzel HJ, Doisy ET, Matt L, Campi KL, Golub MS, Nerbonne JM, Hell JW, Trainor BC, Sack JT, Schwartzkroin PA, Trimmer JS.

Genes Brain Behav. 2014 Apr;13(4):394-408. doi: 10.1111/gbb.12120. Epub 2014 Mar 7.


Conserved role of unc-79 in ethanol responses in lightweight mutant mice.

Speca DJ, Chihara D, Ashique AM, Bowers MS, Pierce-Shimomura JT, Lee J, Rabbee N, Speed TP, Gularte RJ, Chitwood J, Medrano JF, Liao M, Sonner JM, Eger EI 2nd, Peterson AS, McIntire SL.

PLoS Genet. 2010 Aug 12;6(8). pii: e1001057. doi: 10.1371/journal.pgen.1001057.


A genetic screen for behavioral mutations that perturb dopaminergic homeostasis in mice.

Speca DJ, Rabbee N, Chihara D, Speed TP, Peterson AS.

Genes Brain Behav. 2006 Feb;5(1):19-28.


Functional identification of a goldfish odorant receptor.

Speca DJ, Lin DM, Sorensen PW, Isacoff EY, Ngai J, Dittman AH.

Neuron. 1999 Jul;23(3):487-98.

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