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Items: 44

1.

Genome-Wide CRISPRi/a Screening in an In Vitro Coculture Assay of Human Immune Cells with Tumor Cells.

Zhang J, Späth SS, Katz SG.

Methods Mol Biol. 2020;2097:231-252. doi: 10.1007/978-1-0716-0203-4_15.

PMID:
31776930
2.

An Overview of Advances in Cell-Based Cancer Immunotherapies Based on the Multiple Immune-Cancer Cell Interactions.

Zhang J, Späth SS, Weissman SM, Katz SG.

Methods Mol Biol. 2020;2097:139-171. doi: 10.1007/978-1-0716-0203-4_10.

PMID:
31776925
3.

Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β.

Komuczki J, Tuzlak S, Friebel E, Hartwig T, Spath S, Rosenstiel P, Waisman A, Opitz L, Oukka M, Schreiner B, Pelczar P, Becher B.

Immunity. 2019 May 21;50(5):1289-1304.e6. doi: 10.1016/j.immuni.2019.04.006. Epub 2019 May 9.

PMID:
31079916
4.

Characterization of cancer genomic heterogeneity by next-generation sequencing advances precision medicine in cancer treatment.

Zhang J, Späth SS, Marjani SL, Zhang W, Pan X.

Precis Clin Med. 2018 Jun;1(1):29-48. doi: 10.1093/pcmedi/pby007. Epub 2018 Jun 14. Review.

5.

Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF-licensed myeloid cells.

Tugues S, Amorim A, Spath S, Martin-Blondel G, Schreiner B, De Feo D, Lutz M, Guscetti F, Apostolova P, Haftmann C, Hasselblatt P, Núñez NG, Hottiger MO, van den Broek M, Manz MG, Zeiser R, Becher B.

Sci Transl Med. 2018 Nov 28;10(469). pii: eaat8410. doi: 10.1126/scitranslmed.aat8410.

PMID:
30487251
6.

Evidence That Rat Chondrocytes Can Differentiate Into Perichondrial Cells.

Späth SS, Andrade AC, Chau M, Baroncelli M, Nilsson O.

JBMR Plus. 2018 Jun 7;2(6):351-361. doi: 10.1002/jbm4.10056. eCollection 2018 Nov.

7.

Attenuated TRAF3 Fosters Activation of Alternative NF-κB and Reduced Expression of Antiviral Interferon, TP53, and RB to Promote HPV-Positive Head and Neck Cancers.

Zhang J, Chen T, Yang X, Cheng H, Späth SS, Clavijo PE, Chen J, Silvin C, Issaeva N, Su X, Yarbrough WG, Annunziata CM, Chen Z, Van Waes C.

Cancer Res. 2018 Aug 15;78(16):4613-4626. doi: 10.1158/0008-5472.CAN-17-0642. Epub 2018 Jun 19.

8.

Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Mathew NR, Baumgartner F, Braun L, O'Sullivan D, Thomas S, Waterhouse M, Müller TA, Hanke K, Taromi S, Apostolova P, Illert AL, Melchinger W, Duquesne S, Schmitt-Graeff A, Osswald L, Yan KL, Weber A, Tugues S, Spath S, Pfeifer D, Follo M, Claus R, Lübbert M, Rummelt C, Bertz H, Wäsch R, Haag J, Schmidts A, Schultheiss M, Bettinger D, Thimme R, Ullrich E, Tanriver Y, Vuong GL, Arnold R, Hemmati P, Wolf D, Ditschkowski M, Jilg C, Wilhelm K, Leiber C, Gerull S, Halter J, Lengerke C, Pabst T, Schroeder T, Kobbe G, Rösler W, Doostkam S, Meckel S, Stabla K, Metzelder SK, Halbach S, Brummer T, Hu Z, Dengjel J, Hackanson B, Schmid C, Holtick U, Scheid C, Spyridonidis A, Stölzel F, Ordemann R, Müller LP, Sicre-de-Fontbrune F, Ihorst G, Kuball J, Ehlert JE, Feger D, Wagner EM, Cahn JY, Schnell J, Kuchenbauer F, Bunjes D, Chakraverty R, Richardson S, Gill S, Kröger N, Ayuk F, Vago L, Ciceri F, Müller AM, Kondo T, Teshima T, Klaeger S, Kuster B, Kim DDH, Weisdorf D, van der Velden W, Dörfel D, Bethge W, Hilgendorf I, Hochhaus A, Andrieux G, Börries M, Busch H, Magenau J, Reddy P, Labopin M, Antin JH, Henden AS, Hill GR, Kennedy GA, Bar M, Sarma A, McLornan D, Mufti G, Oran B, Rezvani K, Shah O, Negrin RS, Nagler A, Prinz M, Burchert A, Neubauer A, Beelen D, Mackensen A, von Bubnoff N, Herr W, Becher B, Socié G, Caligiuri MA, Ruggiero E, Bonini C, Häcker G, Duyster J, Finke J, Pearce E, Blazar BR, Zeiser R.

Nat Med. 2018 Apr 10;24(4):526. doi: 10.1038/nm0418-526c.

PMID:
29634689
9.

Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

Mathew NR, Baumgartner F, Braun L, O'Sullivan D, Thomas S, Waterhouse M, Müller TA, Hanke K, Taromi S, Apostolova P, Illert AL, Melchinger W, Duquesne S, Schmitt-Graeff A, Osswald L, Yan KL, Weber A, Tugues S, Spath S, Pfeifer D, Follo M, Claus R, Lübbert M, Rummelt C, Bertz H, Wäsch R, Haag J, Schmidts A, Schultheiss M, Bettinger D, Thimme R, Ullrich E, Tanriver Y, Vuong GL, Arnold R, Hemmati P, Wolf D, Ditschkowski M, Jilg C, Wilhelm K, Leiber C, Gerull S, Halter J, Lengerke C, Pabst T, Schroeder T, Kobbe G, Rösler W, Doostkam S, Meckel S, Stabla K, Metzelder SK, Halbach S, Brummer T, Hu Z, Dengjel J, Hackanson B, Schmid C, Holtick U, Scheid C, Spyridonidis A, Stölzel F, Ordemann R, Müller LP, Sicre-de-Fontbrune F, Ihorst G, Kuball J, Ehlert JE, Feger D, Wagner EM, Cahn JY, Schnell J, Kuchenbauer F, Bunjes D, Chakraverty R, Richardson S, Gill S, Kröger N, Ayuk F, Vago L, Ciceri F, Müller AM, Kondo T, Teshima T, Klaeger S, Kuster B, Kim DDH, Weisdorf D, van der Velden W, Dörfel D, Bethge W, Hilgendorf I, Hochhaus A, Andrieux G, Börries M, Busch H, Magenau J, Reddy P, Labopin M, Antin JH, Henden AS, Hill GR, Kennedy GA, Bar M, Sarma A, McLornan D, Mufti G, Oran B, Rezvani K, Shah O, Negrin RS, Nagler A, Prinz M, Burchert A, Neubauer A, Beelen D, Mackensen A, von Bubnoff N, Herr W, Becher B, Socié G, Caligiuri MA, Ruggiero E, Bonini C, Häcker G, Duyster J, Finke J, Pearce E, Blazar BR, Zeiser R.

Nat Med. 2018 Mar;24(3):282-291. doi: 10.1038/nm.4484. Epub 2018 Feb 12. Erratum in: Nat Med. 2018 Apr 10;24(4):526.

10.

Nanostructured micro-raspberries from superparamagnetic iron oxide nanoparticles: Studying agglomeration degree and redispersibility of nanoparticulate powders via magnetisation measurements.

Stauch C, Späth S, Ballweg T, Luxenhofer R, Mandel K.

J Colloid Interface Sci. 2017 Nov 1;505:605-614. doi: 10.1016/j.jcis.2017.06.047. Epub 2017 Jun 16.

PMID:
28651200
11.

Dysregulation of the Cytokine GM-CSF Induces Spontaneous Phagocyte Invasion and Immunopathology in the Central Nervous System.

Spath S, Komuczki J, Hermann M, Pelczar P, Mair F, Schreiner B, Becher B.

Immunity. 2017 Feb 21;46(2):245-260. doi: 10.1016/j.immuni.2017.01.007.

12.

Cytokine networks in neuroinflammation.

Becher B, Spath S, Goverman J.

Nat Rev Immunol. 2017 Jan;17(1):49-59. doi: 10.1038/nri.2016.123. Epub 2016 Dec 5. Review.

PMID:
27916979
13.

Chondroprotective effect of high-molecular-weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation inflammation model with M1 macrophages.

Bauer C, Niculescu-Morzsa E, Jeyakumar V, Kern D, Späth SS, Nehrer S.

J Inflamm (Lond). 2016 Sep 13;13(1):31. doi: 10.1186/s12950-016-0139-y. eCollection 2016.

14.

Distribution of prostate nodes: a PET/CT-derived anatomic atlas of prostate cancer patients before and after surgical treatment.

Hegemann NS, Wenter V, Spath S, Kusumo N, Li M, Bartenstein P, Fendler WP, Stief C, Belka C, Ganswindt U.

Radiat Oncol. 2016 Mar 11;11:37. doi: 10.1186/s13014-016-0615-9.

15.

Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases.

Ruggeri RB, Buckbinder L, Bagley SW, Carpino PA, Conn EL, Dowling MS, Fernando DP, Jiao W, Kung DW, Orr ST, Qi Y, Rocke BN, Smith A, Warmus JS, Zhang Y, Bowles D, Widlicka DW, Eng H, Ryder T, Sharma R, Wolford A, Okerberg C, Walters K, Maurer TS, Zhang Y, Bonin PD, Spath SN, Xing G, Hepworth D, Ahn K, Kalgutkar AS.

J Med Chem. 2015 Nov 12;58(21):8513-28. doi: 10.1021/acs.jmedchem.5b00963. Epub 2015 Oct 28.

PMID:
26509551
16.

GM-CSF in Neuroinflammation: Licensing Myeloid Cells for Tissue Damage.

Croxford AL, Spath S, Becher B.

Trends Immunol. 2015 Oct;36(10):651-662. doi: 10.1016/j.it.2015.08.004. Review.

PMID:
26431942
17.

Integrated transcriptional profiling and genomic analyses reveal RPN2 and HMGB1 as promising biomarkers in colorectal cancer.

Zhang J, Yan B, Späth SS, Qun H, Cornelius S, Guan D, Shao J, Hagiwara K, Van Waes C, Chen Z, Su X, Bi Y.

Cell Biosci. 2015 Sep 17;5:53. doi: 10.1186/s13578-015-0043-9. eCollection 2015.

18.

Impact of Particle Size of Ceramic Granule Blends on Mechanical Strength and Porosity of 3D Printed Scaffolds.

Spath S, Drescher P, Seitz H.

Materials (Basel). 2015 Jul 24;8(8):4720-4732. doi: 10.3390/ma8084720.

19.

Helicobacter pylori-specific protection against inflammatory bowel disease requires the NLRP3 inflammasome and IL-18.

Engler DB, Leonardi I, Hartung ML, Kyburz A, Spath S, Becher B, Rogler G, Müller A.

Inflamm Bowel Dis. 2015 Apr;21(4):854-61. doi: 10.1097/MIB.0000000000000318.

20.
21.

Gene expression profiling reveals similarities between the spatial architectures of postnatal articular and growth plate cartilage.

Chau M, Lui JC, Landman EB, Späth SS, Vortkamp A, Baron J, Nilsson O.

PLoS One. 2014 Jul 28;9(7):e103061. doi: 10.1371/journal.pone.0103061. eCollection 2014.

22.

Mechanistic characterization of a 2-thioxanthine myeloperoxidase inhibitor and selectivity assessment utilizing click chemistry--activity-based protein profiling.

Ward J, Spath SN, Pabst B, Carpino PA, Ruggeri RB, Xing G, Speers AE, Cravatt BF, Ahn K.

Biochemistry. 2013 Dec 23;52(51):9187-201. doi: 10.1021/bi401354d. Epub 2013 Dec 9.

PMID:
24320749
23.

T-bet or not T-bet: taking the last bow on the autoimmunity stage.

Spath S, Becher B.

Eur J Immunol. 2013 Nov;43(11):2810-3. doi: 10.1002/eji.201344109. Epub 2013 Oct 21.

24.

Deconstruction of activity-dependent covalent modification of heme in human neutrophil myeloperoxidase by multistage mass spectrometry (MS(4)).

Geoghegan KF, Varghese AH, Feng X, Bessire AJ, Conboy JJ, Ruggeri RB, Ahn K, Spath SN, Filippov SV, Conrad SJ, Carpino PA, Guimarães CR, Vajdos FF.

Biochemistry. 2012 Mar 13;51(10):2065-77. doi: 10.1021/bi201872j. Epub 2012 Mar 1.

PMID:
22352991
25.

Independent roles of apical membrane antigen 1 and rhoptry neck proteins during host cell invasion by apicomplexa.

Giovannini D, Späth S, Lacroix C, Perazzi A, Bargieri D, Lagal V, Lebugle C, Combe A, Thiberge S, Baldacci P, Tardieux I, Ménard R.

Cell Host Microbe. 2011 Dec 15;10(6):591-602. doi: 10.1016/j.chom.2011.10.012.

26.

FLP/FRT-mediated conditional mutagenesis in pre-erythrocytic stages of Plasmodium berghei.

Lacroix C, Giovannini D, Combe A, Bargieri DY, Späth S, Panchal D, Tawk L, Thiberge S, Carvalho TG, Barale JC, Bhanot P, Ménard R.

Nat Protoc. 2011 Aug 25;6(9):1412-28. doi: 10.1038/nprot.2011.363.

PMID:
21886105
27.

Local regulation of growth plate cartilage.

Späth SS, Andrade AC, Chau M, Nilsson O.

Endocr Dev. 2011;21:12-22. doi: 10.1159/000328084. Epub 2011 Aug 22. Review.

PMID:
21865750
28.

Highlights from the Second European Workshop on Growth Plate Research 2010.

Späth SS, Sävendahl L, Camacho-Hübner C, Nilsson O.

Pediatr Endocrinol Rev. 2010 Dec;8(2):123-5. No abstract available.

PMID:
21174900
29.

Direct measurement of myocardial oxygen tension and high energy phosphate content under varying ventilatory conditions in rabbits.

Vogt S, Troitzsch D, Spath S, Portig I, Moosdorf R.

Biomed Tech (Berl). 2009 Aug;54(4):179-86. doi: 10.1515/BMT.2009.025.

PMID:
19807283
30.

Clonal conditional mutagenesis in malaria parasites.

Combe A, Giovannini D, Carvalho TG, Spath S, Boisson B, Loussert C, Thiberge S, Lacroix C, Gueirard P, Ménard R.

Cell Host Microbe. 2009 Apr 23;5(4):386-96. doi: 10.1016/j.chom.2009.03.008.

31.

The spectrum of Trp- mutants isolated as 5-fluoroanthranilate-resistant clones in Saccharomyces bayanus, S. mikatae and S. paradoxus.

Jones EW, Berget PB, Burnette JM 3rd, Anderson C, Asafu-Adjei D, Avetisian S, Barrie F, Chen R, Chu B, Conroy S, Conroy S, Dill A, Eimer W, Garrity D, Greenwood A, Hamilton T, Hucko S, Jackson C, Livesey K, Monaco T, Onorato C, Otsuka M, Pai S, Schaeffer G, Shung S, Spath S, Stahlman J, Sweeney B, Wiltrout E, Yurovsky D, Zonneveld A.

Yeast. 2008 Jan;25(1):41-6.

32.

Efficacy of ion-selective probes in early epicardial in vivo detection of myocardial ischemia.

Vogt S, Troitzsch D, Späth S, Moosdorf R.

Physiol Meas. 2004 Dec;25(6):N21-6.

PMID:
15712731
33.

[Detection of myocardial ischemia by epicardial detection of potassium ion activity].

Vogt S, Troitzsch D, Späth S, Moosdorf R.

Biomed Tech (Berl). 2002 Nov;47(11):294-301. German.

PMID:
12494551
34.

Hone your project management skills.

Spath S.

Hosp Peer Rev. 2001 Jul;26(7):101-3. No abstract available.

PMID:
11431975
35.

[Measuring stroke volume of the ascending aorta with an extravascular Doppler ultrasound probe in comparison with aortic thermodilution].

Vogt S, Troitzsch D, Abdul-Khaliq H, Späth S, Wolff MH, Lange PE, Moosdorf R.

Biomed Tech (Berl). 2000 Apr;45(4):78-81. German.

PMID:
10829540
36.

[Animal experiment study of the design of microelectrodes for selective detection of epicardial potassium ion activities].

Vogt S, Troitzsch D, Späth S, Moosdorf R.

Biomed Tech (Berl). 1998 Oct;43(10):293-8. German.

PMID:
9846446
37.
38.
39.

23Na and 31P NMR studies of the effects of salt stress on the freshwater cyanobacterium Synechococcus 6311.

Packer L, Spath S, Martin JB, Roby C, Bligny R.

Arch Biochem Biophys. 1987 Jul;256(1):354-61.

PMID:
3038026
40.
41.

[Intraoperative electroneurography during decompression of the median nerve in the carpal tunnel].

Späth S, Holzhauser P, Wessinghage D.

Handchir Mikrochir Plast Chir. 1985 Sep;17(5):273-6. German.

PMID:
4065714
42.

The role of Na2S in anoxygenic photosynthesis and H2 production in the cyanobacterium Nostoc muscorum.

Fry I, Robinson AE, Spath S, Packer L.

Biochem Biophys Res Commun. 1984 Sep 28;123(3):1138-43.

PMID:
6091649
43.

[Meralgia paresthesia should also be considered in coxarthrosis].

Schrott E, Späth S, Holzhauser P.

Z Orthop Ihre Grenzgeb. 1983 Nov-Dec;121(6):703-5. German.

PMID:
6666248
44.

Membrane-membrane and membrane-ligand interactions in Chlamydomonas mating.

Goodenough UW, Adair WS, Caligor E, Forest CL, Hoffman JL, Mesland DA, Spath S.

Soc Gen Physiol Ser. 1980;34:131-52.

PMID:
7384832

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