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Items: 50

1.

Establishment of a novel extracorporeal bowel model to study luminal approaches to treat inflammatory bowel disease.

Breitrück A, Sparmann G, Mitzner S, Kerkhoff C.

Dis Model Mech. 2013 Nov;6(6):1487-93. doi: 10.1242/dmm.011734. Epub 2013 Aug 14.

2.

First human application of a novel adsorptive-type cytapheresis module in patients with active ulcerative colitis: a pilot study.

Ramlow W, Waitz G, Sparmann G, Prophet H, Bodammer P, Emmrich J.

Ther Apher Dial. 2013 Jun;17(3):339-47. doi: 10.1111/1744-9987.12007. Epub 2013 Mar 1.

PMID:
23735151
3.

Calpain mediates caspase-dependent apoptosis initiated by hydrogen peroxide in pancreatic acinar AR42J cells.

Weber H, Müller L, Jonas L, Schult C, Sparmann G, Schuff-Werner P.

Free Radic Res. 2013 May;47(5):432-46. doi: 10.3109/10715762.2013.785633. Epub 2013 Apr 8.

PMID:
23495712
4.

Differentiation potential of pancreatic fibroblastoid cells/stellate cells: effects of peroxisome proliferator-activated receptor gamma ligands.

Kruse ML, Hopf-Jensen S, Timke C, Agricola B, Sparmann G, Schmid A, Sipos B, Arlt A, Schäfer H.

Int J Cell Biol. 2011;2011:816791. doi: 10.1155/2011/816791. Epub 2011 Oct 4.

5.

Prof. Dr. Jörg Emmrich, MD.

Jaster R, Sparmann G, Liebe S.

Pancreatology. 2011;11(2):III-IV. doi: 10.1159/000330572. Epub 2011 Jul 19. No abstract available.

6.

Bone marrow-derived pancreatic stellate cells in rats.

Sparmann G, Kruse ML, Hofmeister-Mielke N, Koczan D, Jaster R, Liebe S, Wolff D, Emmrich J.

Cell Res. 2010 Mar;20(3):288-98. doi: 10.1038/cr.2010.10. Epub 2010 Jan 26.

PMID:
20101265
7.

Molecular insights into connective tissue growth factor action in rat pancreatic stellate cells.

Karger A, Fitzner B, Brock P, Sparmann G, Emmrich J, Liebe S, Jaster R.

Cell Signal. 2008 Oct;20(10):1865-72. doi: 10.1016/j.cellsig.2008.06.016. Epub 2008 Jul 2.

PMID:
18639630
8.

Synergistic growth inhibitory effects of the dual endothelin-1 receptor antagonist bosentan on pancreatic stellate and cancer cells.

Fitzner B, Brock P, Holzhüter SA, Nizze H, Sparmann G, Emmrich J, Liebe S, Jaster R.

Dig Dis Sci. 2009 Feb;54(2):309-20. doi: 10.1007/s10620-008-0366-z. Epub 2008 Jul 10.

PMID:
18612819
9.

Granzyme K: a novel mediator in acute airway inflammation.

Bratke K, Klug A, Julius P, Kuepper M, Lommatzsch M, Sparmann G, Luttmann W, Virchow JC.

Thorax. 2008 Nov;63(11):1006-11. doi: 10.1136/thx.2007.091215. Epub 2008 Jun 17.

PMID:
18559365
10.

Antifibrogenic effects of histone deacetylase inhibitors on pancreatic stellate cells.

Bülow R, Fitzner B, Sparmann G, Emmrich J, Liebe S, Jaster R.

Biochem Pharmacol. 2007 Dec 15;74(12):1747-57. Epub 2007 Aug 21.

PMID:
17889833
11.

Hydrogen peroxide-induced activation of defense mechanisms against oxidative stress in rat pancreatic acinar AR42J cells.

Weber H, Hühns S, Jonas L, Sparmann G, Bastian M, Schuff-Werner P.

Free Radic Biol Med. 2007 Mar 15;42(6):830-41. Epub 2006 Dec 22.

PMID:
17320765
12.

Adenovirus-mediated gene transfer of interleukin-4 into pancreatic stellate cells promotes interleukin-10 expression.

Brock P, Sparmann G, Ritter T, Jaster R, Liebe S, Emmrich J.

J Cell Mol Med. 2006 Oct-Dec;10(4):884-95.

13.

Inhibitory effects of interferon-gamma on activation of rat pancreatic stellate cells are mediated by STAT1 and involve down-regulation of CTGF expression.

Fitzner B, Brock P, Nechutova H, Glass A, Karopka T, Koczan D, Thiesen HJ, Sparmann G, Emmrich J, Liebe S, Jaster R.

Cell Signal. 2007 Apr;19(4):782-90. Epub 2006 Nov 20.

PMID:
17116388
14.

Delayed response toward activation stimuli in pancreatic stellate cells.

Glass A, Kundt G, Brock P, Jaster R, Liebe S, Emmrich J, Sparmann G.

Pancreas. 2006 Oct;33(3):293-300.

PMID:
17003652
15.

Cis-hydroxyproline-induced inhibition of pancreatic cancer cell growth is mediated by endoplasmic reticulum stress.

Mueller C, Emmrich J, Jaster R, Braun D, Liebe S, Sparmann G.

World J Gastroenterol. 2006 Mar 14;12(10):1569-76.

16.

Inhibitory effects of interferons on pancreatic stellate cell activation.

Baumert JT, Sparmann G, Emmrich J, Liebe S, Jaster R.

World J Gastroenterol. 2006 Feb 14;12(6):896-901.

17.

Peroxisome proliferator-activated receptor gamma overexpression inhibits pro-fibrogenic activities of immortalised rat pancreatic stellate cells.

Jaster R, Lichte P, Fitzner B, Brock P, Glass A, Karopka T, Gierl L, Koczan D, Thiesen HJ, Sparmann G, Emmrich J, Liebe S.

J Cell Mol Med. 2005 Jul-Sep;9(3):670-82.

18.

Interleukin-4 gene transfer into rat pancreas by recombinant adenovirus.

Brock P, Sparmann G, Ritter T, Jaster R, Liebe S, Emmrich J.

Scand J Gastroenterol. 2005 Sep;40(9):1109-17.

PMID:
16165721
19.

Galectin-1 is an inductor of pancreatic stellate cell activation.

Fitzner B, Walzel H, Sparmann G, Emmrich J, Liebe S, Jaster R.

Cell Signal. 2005 Oct;17(10):1240-7. Epub 2005 Jan 21.

PMID:
16038798
20.

Inhibition of lymphocyte apoptosis by pancreatic stellate cells: impact of interleukin-15.

Sparmann G, Glass A, Brock P, Jaster R, Koczan D, Thiesen HJ, Liebe S, Emmrich J.

Am J Physiol Gastrointest Liver Physiol. 2005 Nov;289(5):G842-51. Epub 2005 Jul 7.

21.

In vitro and in vivo evaluation of Adacolumn cytapheresis in healthy subjects.

Ramlow W, Emmrich J, Ahrenholz P, Sparmann G, Kashiwagi N, Franz M, Yokoyama T, Yoshikawa T.

J Clin Apher. 2005 Jul;20(2):72-80.

PMID:
15892085
22.

In vivo characterization of developing chronic pancreatitis in rats.

Glawe C, Emmrich J, Sparmann G, Vollmar B.

Lab Invest. 2005 Feb;85(2):193-204.

23.

Generation and characterization of immortalized rat pancreatic stellate cells.

Sparmann G, Hohenadl C, Tornøe J, Jaster R, Fitzner B, Koczan D, Thiesen HJ, Glass A, Winder D, Liebe S, Emmrich J.

Am J Physiol Gastrointest Liver Physiol. 2004 Jul;287(1):G211-9. Epub 2004 Feb 19.

24.

Involvement of AP-1 proteins in pancreatic stellate cell activation in vitro.

Fitzner B, Sparmann G, Emmrich J, Liebe S, Jaster R.

Int J Colorectal Dis. 2004 Sep;19(5):414-20. Epub 2004 Jan 15.

PMID:
14727130
25.

Regulation of pancreatic stellate cell function in vitro: biological and molecular effects of all-trans retinoic acid.

Jaster R, Hilgendorf I, Fitzner B, Brock P, Sparmann G, Emmrich J, Liebe S.

Biochem Pharmacol. 2003 Aug 15;66(4):633-41.

PMID:
12906928
26.

Immunologic characterization of acute pancreatitis in rats induced by dibutyltin dichloride (DBTC).

Hense S, Sparmann G, Weber H, Liebe S, Emmrich J.

Pancreas. 2003 Jul;27(1):e6-12.

PMID:
12826912
27.

Inhibition of pancreatic stellate cell activation by the hydroxymethylglutaryl coenzyme A reductase inhibitor lovastatin.

Jaster R, Brock P, Sparmann G, Emmrich J, Liebe S.

Biochem Pharmacol. 2003 Apr 15;65(8):1295-303.

PMID:
12694870
28.

The fate of effector T cells in vivo is determined during activation and differs for CD4+ and CD8+ cells.

Bode U, Sahle A, Sparmann G, Weidner F, Westermann J.

J Immunol. 2002 Dec 1;169(11):6085-91.

29.
30.

Persistence of memory type lymphocytes in an experimental model of chronic pancreatitis in rats.

Sparmann G, Sass S, Böhme HJ, Liebe S, Emmrich J.

Cell Mol Biol (Noisy-le-grand). 2002 May;48(3):309-15.

PMID:
12030436
31.

Expression of hepatocyte growth factor, keratinocyte growth factor and their receptors in experimental chronic pancreatitis.

Otte JM, Schwenger M, Brunke G, Sparmann G, Emmrich J, Schmitz F, Fölsch UR, Herzig KH.

Eur J Clin Invest. 2001 Oct;31(10):865-75.

PMID:
11737224
32.

Cytokine mRNA levels and lymphocyte infiltration in pancreatic tissue during experimental chronic pancreatitis induced by dibutyltin dichloride.

Sparmann G, Behrend S, Merkord J, Kleine HD, Graser E, Ritter T, Liebe S, Emmrich J.

Dig Dis Sci. 2001 Aug;46(8):1647-56.

PMID:
11508663
34.

The course of pancreatic fibrosis induced by dibutyltin dichloride (DBTC).

Merkord J, Weber H, Sparmann G, Jonas L, Hennighausen G.

Ann N Y Acad Sci. 1999 Jun 30;880:231-7.

PMID:
10415868
35.

Typing of leukocytes in pancreatic tissue surrounding human pancreatic carcinoma.

Emmrich J, Sparmann G, Hopt U, Löhr M, Liebe S.

Ann N Y Acad Sci. 1999 Jun 30;880:171-4. No abstract available.

PMID:
10415861
36.

Immunohistochemical characterization of the pancreatic cellular infiltrate in normal pancreas, chronic pancreatitis and pancreatic carcinoma.

Emmrich J, Weber I, Nausch M, Sparmann G, Koch K, Seyfarth M, Löhr M, Liebe S.

Digestion. 1998;59(3):192-8.

PMID:
9643678
37.

Secretory immunoglobulin A in pancreatic juice and pancreatic tissue of patients with chronic pancreatitis.

Emmrich J, Seyfarth M, Conradi P, Plath F, Sparmann G, Löhr M, Liebe S.

Gut. 1998 Mar;42(3):436-41.

38.

Caerulein pancreatitis increases mRNA but reduces protein levels of rat pancreatic heat shock proteins.

Strowski MZ, Sparmann G, Weber H, Fiedler F, Printz H, Jonas L, Göke B, Wagner AC.

Am J Physiol. 1997 Oct;273(4):G937-45. doi: 10.1152/ajpgi.1997.273.4.G937.

PMID:
9357838
39.

Regulated gene expression after retroviral vector-mediated delivery of cancer-relevant therapeutic genes.

Günzburg WH, Karle P, Mrochen S, Sparmann G, Saller R, Klein D, Uckert W, Salmons B.

Recent Results Cancer Res. 1998;144:116-26. Review. No abstract available.

PMID:
9304713
40.

Pancreatic fibrosis in experimental pancreatitis induced by dibutyltin dichloride.

Sparmann G, Merkord J, Jäschke A, Nizze H, Jonas L, Löhr M, Liebe S, Emmrich J.

Gastroenterology. 1997 May;112(5):1664-72.

PMID:
9136846
41.

Tissue homogenization as a key step in extracting RNA from human and rat pancreatic tissue.

Sparmann G, Jäschke A, Loehr M, Liebe S, Emmrich J.

Biotechniques. 1997 Mar;22(3):408-10, 412. No abstract available.

42.

Conditional expression of human TNF-alpha: a system for inducible cytotoxicity.

Sparmann G, Walther W, Günzburg WH, Uckert W, Salmons B.

Int J Cancer. 1994 Oct 1;59(1):103-7.

PMID:
7927889
43.

Interaction of adrenal and pancreatic hormones in the control of hepatic enzymes during development.

Böhme HJ, Belay D, Dettmer D, Goltzsch W, Hofmann E, Lange R, Schubert C, Schulze E, Sparmann G, Weiss E.

Adv Enzyme Regul. 1987;26:31-61.

PMID:
2890281
44.

[Trials on bulla induction by antibodies from bullous pemphigoid patients in vivo and in vitro].

Lohrisch I, Noack H, Haustein UF, Sparmann G, Koch J.

Dermatol Monatsschr. 1985;171(2):106-12. German. No abstract available.

PMID:
3884399
45.

Biochemistry of liver development in the perinatal period.

Böhme HJ, Sparmann G, Hofmann E.

Experientia. 1983 May 15;39(5):473-83. Review.

PMID:
6133774
46.

[Determination of the gestational age of Wistar rats].

Goltzsch W, Bittner R, Didt L, Sparmann G, Böhme HJ, Hofmann E.

Z Versuchstierkd. 1980;22(1):1-7. German. No abstract available.

PMID:
7405421
47.

Developmental changes in the levels of hepatic enzymes and their relation to metabolic functions.

Bittner R, Böhme HJ, Didt L, Goltzsch W, Hofmann E, Levin MJ, Sparmann G.

Adv Enzyme Regul. 1978;17:37-57. No abstract available.

PMID:
757313
48.

Alanine-mediated reversible inactivation of tumour pyruvate kinase caused by a tetramer-dimer transition.

Schulz J, Sparmann G, Hofmann E.

FEBS Lett. 1975 Feb 15;50(3):346-50. No abstract available.

49.

Association-dissociation behavior of erythrocyte phosphofructokinase and tumor pyruvate kinase.

Hofmann E, Kurganov BI, Schellenberger W, Schulz J, Sparmann G, Wenzel KW, Zimmermann G.

Adv Enzyme Regul. 1975;13:247-77. No abstract available.

PMID:
128996
50.

Effects of L-alanine and fructose (1,6-diphosphate) on pyruvate kinase from ehrlich ascites tumour cells.

Sparmann G, Schulz J, Hofmann E.

FEBS Lett. 1973 Nov 1;36(3):305-8. No abstract available.

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