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Items: 1 to 50 of 154

1.

A doctor's dilemma: choices amidst change.

Sparling PF.

J Clin Invest. 2015 Sep;125(9):3330-4. doi: 10.1172/JCI83584. Epub 2015 Aug 4. No abstract available.

2.

Lipid A's structure mediates Neisseria gonorrhoeae fitness during experimental infection of mice and men.

Hobbs MM, Anderson JE, Balthazar JT, Kandler JL, Carlson RW, Ganguly J, Begum AA, Duncan JA, Lin JT, Sparling PF, Jerse AE, Shafer WM.

MBio. 2013 Nov 19;4(6):e00892-13. doi: 10.1128/mBio.00892-13.

3.

The emerging threat of untreatable gonococcal infection.

Bolan GA, Sparling PF, Wasserheit JN.

N Engl J Med. 2012 Feb 9;366(6):485-7. doi: 10.1056/NEJMp1112456. No abstract available.

PMID:
22316442
4.

Experimental Gonococcal Infection in Male Volunteers: Cumulative Experience with Neisseria gonorrhoeae Strains FA1090 and MS11mkC.

Hobbs MM, Sparling PF, Cohen MS, Shafer WM, Deal CD, Jerse AE.

Front Microbiol. 2011 May 31;2:123. doi: 10.3389/fmicb.2011.00123. eCollection 2011.

5.

Vaccines for gonorrhea: can we rise to the challenge?

Zhu W, Chen CJ, Thomas CE, Anderson JE, Jerse AE, Sparling PF.

Front Microbiol. 2011 Jun 3;2:124. doi: 10.3389/fmicb.2011.00124. eCollection 2011.

6.

Novel Treponema pallidum serologic tests: a paradigm shift in syphilis screening for the 21st century.

Seña AC, White BL, Sparling PF.

Clin Infect Dis. 2010 Sep 15;51(6):700-8. doi: 10.1086/655832. Review.

PMID:
20687840
7.

Diagnosis of neurosyphilis: New tools.

Sparling PF.

Sex Transm Dis. 2010 May;37(5):288-9. No abstract available.

PMID:
20429086
8.

Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome.

Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP.

J Immunol. 2009 May 15;182(10):6460-9. doi: 10.4049/jimmunol.0802696.

9.

Species status of Neisseria gonorrhoeae: evolutionary and epidemiological inferences from multilocus sequence typing.

Bennett JS, Jolley KA, Sparling PF, Saunders NJ, Hart CA, Feavers IM, Maiden MC.

BMC Biol. 2007 Sep 7;5:35.

10.

A vaccine for genital HPV: a time to rejoice!

Sparling PF.

N C Med J. 2006 Sep-Oct;67(5):384-5. No abstract available.

PMID:
17203643
11.

Syphilis management in St. Petersburg, Russia: 1995-2001.

Yakubovsky A, Sokolovsky E, Miller WC, Sparling PF, Ryder RW, Hoffman IF.

Sex Transm Dis. 2006 Apr;33(4):244-9.

PMID:
16565645
12.

Vaccination of mice with gonococcal TbpB expressed in vivo from Venezuelan equine encephalitis viral replicon particles.

Thomas CE, Zhu W, Van Dam CN, Davis NL, Johnston RE, Sparling PF.

Infect Immun. 2006 Mar;74(3):1612-20.

13.
15.

A mutant form of the Neisseria gonorrhoeae pilus secretin protein PilQ allows increased entry of heme and antimicrobial compounds.

Chen CJ, Tobiason DM, Thomas CE, Shafer WM, Seifert HS, Sparling PF.

J Bacteriol. 2004 Feb;186(3):730-9.

16.

Opposing selective forces for expression of the gonococcal lactoferrin receptor.

Anderson JE, Hobbs MM, Biswas GD, Sparling PF.

Mol Microbiol. 2003 Jun;48(5):1325-37.

17.

A plethora of host factors that determine the outcome of meningococcal infection.

Sparling PF.

Am J Med. 2002 Jan;112(1):72-4. No abstract available.

PMID:
11812411
18.

Point mutations in HpuB enable gonococcal HpuA deletion mutants to grow on hemoglobin.

Chen CJ, Mclean D, Thomas CE, Anderson JE, Sparling PF.

J Bacteriol. 2002 Jan;184(2):420-6.

19.

Selection for expression of the gonococcal hemoglobin receptor during menses.

Anderson JE, Leone PA, Miller WC, Chen C, Hobbs MM, Sparling PF.

J Infect Dis. 2001 Dec 15;184(12):1621-3. Epub 2001 Nov 6.

PMID:
11740741
20.

Shortages of antibiotics, antivirals, and vaccines threaten the public health.

Sparling PF.

Clin Infect Dis. 2001 Nov 1;33(9):1502-3. Epub 2001 Oct 4. No abstract available.

PMID:
11588696
21.

Neisserial TonB-dependent outer-membrane proteins: detection, regulation and distribution of three putative candidates identified from the genome sequences.

Turner PC, Thomas CE, Stojiljkovic I, Elkins C, Kizel G, Ala'Aldeen DA, Sparling PF.

Microbiology. 2001 May;147(Pt 5):1277-90.

PMID:
11320131
22.

Antigenic and sequence diversity in gonococcal transferrin-binding protein A.

Cornelissen CN, Anderson JE, Boulton IC, Sparling PF.

Infect Immun. 2000 Aug;68(8):4725-35.

23.

Phase variation of the gonococcal siderophore receptor FetA.

Carson SD, Stone B, Beucher M, Fu J, Sparling PF.

Mol Microbiol. 2000 May;36(3):585-93.

24.

Proposed changes for NIH's Center for Scientific Review. Panel on Scientific Boundaries for Review. Center for Scientific Review Advisory Committee, National Institutes of Health.

Alberts BM, Ayala FJ, Botstein D, Frank E, Holmes EW, Lee RD, Macagno ER, Marrack P, Oparil S, Orkin SH, Rubenstein AH, Slayman CW, Sparling PF, Squire LR, von Hippel PH, Yamamoto KR.

Science. 1999 Jul 30;285(5428):666-7. No abstract available.

25.

An epidemiological evaluation of the use of microbiological tools for identifying gonorrhoea infection networks.

Pierce RL, Thomas JC, Sparling PF, Fisher W, Davis RH, Alcorn T, Cohen M.

Int J STD AIDS. 1999 May;10(5):316-23.

PMID:
10361921
26.

Ferric enterobactin binding and utilization by Neisseria gonorrhoeae.

Carson SD, Klebba PE, Newton SM, Sparling PF.

J Bacteriol. 1999 May;181(9):2895-901.

27.

Longitudinal evaluation of serovar-specific immunity to Neisseria gonorrhoeae.

Fox KK, Thomas JC, Weiner DH, Davis RH, Sparling PF, Cohen MS.

Am J Epidemiol. 1999 Feb 15;149(4):353-8.

PMID:
10025478
28.

Molecular typing of Neisseria gonorrhoeae causing repeated infections: evolution of porin during passage within a community.

Hobbs MM, Alcorn TM, Davis RH, Fischer W, Thomas JC, Martin I, Ison C, Sparling PF, Cohen MS.

J Infect Dis. 1999 Feb;179(2):371-81.

PMID:
9878021
29.

The Impact of Molecular Technology on STD Control : A Historical Perspective.

Sparling PF.

Methods Mol Med. 1999;20:3-11. doi: 10.1385/0-89603-535-2:3.

PMID:
21390725
30.

Iron and infection.

Sparling PF.

Clin Infect Dis. 1998 Dec;27(6):1367-8. No abstract available.

PMID:
9868643
31.

Identification and functional characterization of the Neisseria gonorrhoeae lbpB gene product.

Biswas GD, Anderson JE, Chen CJ, Cornelissen CN, Sparling PF.

Infect Immun. 1999 Jan;67(1):455-9.

32.
33.

The transferrin receptor expressed by gonococcal strain FA1090 is required for the experimental infection of human male volunteers.

Cornelissen CN, Kelley M, Hobbs MM, Anderson JE, Cannon JG, Cohen MS, Sparling PF.

Mol Microbiol. 1998 Feb;27(3):611-6.

34.

Phase variation of hemoglobin utilization in Neisseria gonorrhoeae.

Chen CJ, Elkins C, Sparling PF.

Infect Immun. 1998 Mar;66(3):987-93.

35.

Energy-dependent changes in the gonococcal transferrin receptor.

Cornelissen CN, Anderson JE, Sparling PF.

Mol Microbiol. 1997 Oct;26(1):25-35.

36.

Cloning and functional characterization of Neisseria gonorrhoeae tonB, exbB and exbD genes.

Biswas GD, Anderson JE, Sparling PF.

Mol Microbiol. 1997 Apr;24(1):169-79.

37.
38.

Pseudo-transposition of a Tn5 derivative in Neisseria gonorrhoeae.

Thomas CE, Carbonetti NH, Sparling PF.

FEMS Microbiol Lett. 1996 Dec 15;145(3):371-6.

PMID:
8978091
39.

Identification and purification of a hemoglobin-binding outer membrane protein from Neisseria gonorrhoeae.

Chen CJ, Sparling PF, Lewis LA, Dyer DW, Elkins C.

Infect Immun. 1996 Dec;64(12):5008-14.

40.
41.

Isolation and analysis of a fur mutant of Neisseria gonorrhoeae.

Thomas CE, Sparling PF.

J Bacteriol. 1996 Jul;178(14):4224-32.

42.

Expression of the CopB outer membrane protein by Moraxella catarrhalis is regulated by iron and affects iron acquisition from transferrin and lactoferrin.

Aebi C, Stone B, Beucher M, Cope LD, Maciver I, Thomas SE, McCracken GH Jr, Sparling PF, Hansen EJ.

Infect Immun. 1996 Jun;64(6):2024-30.

44.

Transferrin increases adherence of iron-deprived Neisseria gonorrhoeae to human endometrial cells.

Heine RP, Elkins C, Wyrick PB, Sparling PF.

Am J Obstet Gynecol. 1996 Feb;174(2):659-66.

PMID:
8623803
45.

A 74-year-old man with swelling and erythema of the right hand--or, the case of the painless nodular growth.

Silverman J, Wilson PA, Sparling PF.

J Am Geriatr Soc. 1995 Sep;43(9):1043-6. No abstract available.

PMID:
7657922
46.
49.

Vaccines for classic sexually transmitted diseases.

Adimora AA, Sparling PF, Cohen MS.

Infect Dis Clin North Am. 1994 Dec;8(4):859-76. Review.

PMID:
7890936
50.

Iron piracy: acquisition of transferrin-bound iron by bacterial pathogens.

Cornelissen CN, Sparling PF.

Mol Microbiol. 1994 Dec;14(5):843-50. Review.

PMID:
7715446

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