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Items: 1 to 50 of 125

1.

A new human calpastatin skipped of the inhibitory region protects calpain-1 from inactivation and degradation.

Sparatore B, Pedrazzi M, Garuti A, Franchi A, Averna M, Ballestrero A, De Tullio R.

Biochim Biophys Acta Mol Cell Res. 2019 Aug;1866(8):1260-1271. doi: 10.1016/j.bbamcr.2019.04.005. Epub 2019 Apr 5.

PMID:
30959065
2.

Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain.

De Tullio R, Franchi A, Martines A, Averna M, Pedrazzi M, Melloni E, Sparatore B.

Biosci Rep. 2018 Apr 20;38(2). pii: BSR20180147. doi: 10.1042/BSR20180147. Print 2018 Apr 26.

3.

Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients.

Averna M, Bavestrello M, Cresta F, Pedrazzi M, De Tullio R, Minicucci L, Sparatore B, Salamino F, Pontremoli S, Melloni E.

Arch Biochem Biophys. 2016 Aug 15;604:103-12. doi: 10.1016/j.abb.2016.06.015. Epub 2016 Jun 25.

PMID:
27349634
4.

NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?

Cantoni C, Huergo-Zapico L, Parodi M, Pedrazzi M, Mingari MC, Moretta A, Sparatore B, Gonzalez S, Olive D, Bottino C, Castriconi R, Vitale M.

J Immunol Res. 2016;2016:4684268. doi: 10.1155/2016/4684268. Epub 2016 May 12. Review.

5.

Natural Killer (NK)/melanoma cell interaction induces NK-mediated release of chemotactic High Mobility Group Box-1 (HMGB1) capable of amplifying NK cell recruitment.

Parodi M, Pedrazzi M, Cantoni C, Averna M, Patrone M, Cavaletto M, Spertino S, Pende D, Balsamo M, Pietra G, Sivori S, Carlomagno S, Mingari MC, Moretta L, Sparatore B, Vitale M.

Oncoimmunology. 2015 May 29;4(12):e1052353. eCollection 2015 Dec.

6.

Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin.

De Tullio R, Averna M, Pedrazzi M, Sparatore B, Salamino F, Pontremoli S, Melloni E.

Biochim Biophys Acta. 2014 Nov;1843(11):2583-91. doi: 10.1016/j.bbamcr.2014.07.002. Epub 2014 Jul 12.

7.

Potentiation of NMDA receptor-dependent cell responses by extracellular high mobility group box 1 protein.

Pedrazzi M, Averna M, Sparatore B, Patrone M, Salamino F, Marcoli M, Maura G, Cervetto C, Frattaroli D, Pontremoli S, Melloni E.

PLoS One. 2012;7(8):e44518. doi: 10.1371/journal.pone.0044518. Epub 2012 Aug 31.

8.

18β-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis.

Cavone L, Muzzi M, Mencucci R, Sparatore B, Pedrazzi M, Moroni F, Chiarugi A.

Ocul Immunol Inflamm. 2011 Jun;19(3):180-5. doi: 10.3109/09273948.2010.538121. Epub 2011 Mar 22.

PMID:
21426233
9.

Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR.

Averna M, Stifanese R, Grosso R, Pedrazzi M, De Tullio R, Salamino F, Sparatore B, Pontremoli S, Melloni E.

Biochim Biophys Acta. 2011 Jan;1813(1):50-9. doi: 10.1016/j.bbamcr.2010.11.008. Epub 2010 Nov 24.

10.

Analysis of NK cell/DC interaction in NK-type lymphoproliferative disease of granular lymphocytes (LDGL): role of DNAM-1 and NKp30.

Balsamo M, Zambello R, Teramo A, Pedrazzi M, Sparatore B, Scordamaglia F, Pende D, Mingari MC, Moretta L, Moretta A, Semenzato G, Vitale M.

Exp Hematol. 2009 Oct;37(10):1167-75. doi: 10.1016/j.exphem.2009.06.010. Epub 2009 Jul 4.

PMID:
19580844
11.

Functional role of the charge at the T538 residue in the control of protein kinase Ctheta.

Passalacqua M, Pedrazzi M, Sparatore B, Patrone M, Pontremoli S, Melloni E.

Arch Biochem Biophys. 2009 Jan 15;481(2):202-9. doi: 10.1016/j.abb.2008.11.013. Epub 2008 Nov 21.

PMID:
19056334
12.

Selective proinflammatory activation of astrocytes by high-mobility group box 1 protein signaling.

Pedrazzi M, Patrone M, Passalacqua M, Ranzato E, Colamassaro D, Sparatore B, Pontremoli S, Melloni E.

J Immunol. 2007 Dec 15;179(12):8525-32.

13.

HMGB1 as an autocrine stimulus in human T98G glioblastoma cells: role in cell growth and migration.

Bassi R, Giussani P, Anelli V, Colleoni T, Pedrazzi M, Patrone M, Viani P, Sparatore B, Melloni E, Riboni L.

J Neurooncol. 2008 Mar;87(1):23-33. Epub 2007 Nov 2.

PMID:
17975708
14.

The high-mobility group box 1 cytokine induces transporter-mediated release of glutamate from glial subcellular particles (gliosomes) prepared from in situ-matured astrocytes.

Bonanno G, Raiteri L, Milanese M, Zappettini S, Melloni E, Pedrazzi M, Passalacqua M, Tacchetti C, Usai C, Sparatore B.

Int Rev Neurobiol. 2007;82:73-93. Review.

PMID:
17678956
15.

High mobility group box 1 protein is released by neural cells upon different stresses and worsens ischemic neurodegeneration in vitro and in vivo.

Faraco G, Fossati S, Bianchi ME, Patrone M, Pedrazzi M, Sparatore B, Moroni F, Chiarugi A.

J Neurochem. 2007 Oct;103(2):590-603. Epub 2007 Jul 31.

16.

The breakpoint identified in a balanced de novo translocation t(7;9)(p14.1;q31.3) disrupts the A-kinase (PRKA) anchor protein 2 gene (AKAP2) on chromosome 9 in a patient with Kallmann syndrome and bone anomalies.

Panza E, Gimelli G, Passalacqua M, Cohen A, Gimelli S, Giglio S, Ghezzi C, Sparatore B, Heye B, Zuffardi O, Rugarli E, Meitinger T, Romeo G, Ravazzolo R, Seri M.

Int J Mol Med. 2007 Mar;19(3):429-35.

PMID:
17273791
17.

Stimulation of excitatory amino acid release from adult mouse brain glia subcellular particles by high mobility group box 1 protein.

Pedrazzi M, Raiteri L, Bonanno G, Patrone M, Ledda S, Passalacqua M, Milanese M, Melloni E, Raiteri M, Pontremoli S, Sparatore B.

J Neurochem. 2006 Nov;99(3):827-38. Epub 2006 Aug 14.

18.

Cutting edge: extracellular high mobility group box-1 protein is a proangiogenic cytokine.

Mitola S, Belleri M, Urbinati C, Coltrini D, Sparatore B, Pedrazzi M, Melloni E, Presta M.

J Immunol. 2006 Jan 1;176(1):12-5.

19.

Activation of A431 human carcinoma cell motility by extracellular high-mobility group box 1 protein and epidermal growth factor stimuli.

Sparatore B, Patrone M, Passalacqua M, Pedrazzi M, Ledda S, Pontremoli S, Melloni E.

Biochem J. 2005 Jul 1;389(Pt 1):215-21.

20.

Role of the kinase activation loop on protein kinase C theta activity and intracellular localisation.

Sparatore B, Passalacqua M, Pedrazzi M, Ledda S, Patrone M, Gaggero D, Pontremoli S, Melloni E.

FEBS Lett. 2003 Nov 6;554(1-2):35-40.

21.

Stimulation of erythroleukaemia cell differentiation by extracellular high-mobility group-box protein 1 is independent of the receptor for advanced glycation end-products.

Sparatore B, Pedrazzi M, Passalacqua M, Gaggero D, Patrone M, Pontremoli S, Melloni E.

Biochem J. 2002 May 1;363(Pt 3):529-35.

22.

Extracellular processing of amphoterin generates a peptide active on erythroleukaemia cell differentiation.

Sparatore B, Patrone M, Passalacqua M, Pedrazzi M, Gaggero D, Pontremoli S, Melloni E.

Biochem J. 2001 Jul 15;357(Pt 2):569-74.

23.

Human neuroblastoma cell differentiation requires protein kinase C-theta.

Sparatore B, Patrone M, Passalacqua M, Pedrazzi M, Pontremoli S, Melloni E.

Biochem Biophys Res Commun. 2000 Dec 20;279(2):589-94.

PMID:
11118330
24.

Neuronal differentiation of PC12 cells involves changes in protein kinase C-theta distribution and molecular properties.

Sparatore B, Patrone M, Passalacqua M, Pedrazzi M, Pontremoli S, Melloni E.

Biochem Biophys Res Commun. 2000 Aug 18;275(1):149-53.

PMID:
10944456
25.

Isolation and characterization of calpain activator protein from bovine brain.

Melloni E, Michetti M, Salamino F, Minafra R, Sparatore B, Pontremoli S.

Methods Mol Biol. 2000;144:99-105. No abstract available.

PMID:
10818753
26.

Acyl-CoA-binding protein is a potent m-calpain activator.

Melloni E, Averna M, Salamino F, Sparatore B, Minafra R, Pontremoli S.

J Biol Chem. 2000 Jan 7;275(1):82-6.

27.

Protein kinase C-theta is specifically activated in murine erythroleukaemia cells during mitosis.

Passalacqua M, Patrone M, Sparatore B, Pedrazzi M, Melloni E, Pontremoli S.

FEBS Lett. 1999 Jun 25;453(3):249-53.

28.

Protein kinase C-theta is specifically localized on centrosomes and kinetochores in mitotic cells.

Passalacqua M, Patrone M, Sparatore B, Melloni E, Pontremoli S.

Biochem J. 1999 Jan 1;337 ( Pt 1):113-8.

29.

Mechanism of action of a new component of the Ca(2+)-dependent proteolytic system in rat brain: the calpain activator.

Melloni E, Michetti M, Salamino F, Sparatore B, Pontremoli S.

Biochem Biophys Res Commun. 1998 Aug 28;249(3):583-8.

PMID:
9731179
30.

Properties of calpastatin forms in rat brain.

Melloni E, De Tullio R, Averna M, Tedesco I, Salamino F, Sparatore B, Pontremoli S.

FEBS Lett. 1998 Jul 10;431(1):55-8.

31.

Rat brain contains multiple mRNAs for calpastatin.

De Tullio R, Sparatore B, Salamino F, Melloni E, Pontremoli S.

FEBS Lett. 1998 Jan 23;422(1):113-7.

32.

Stimulated astrocytes release high-mobility group 1 protein, an inducer of LAN-5 neuroblastoma cell differentiation.

Passalacqua M, Patrone M, Picotti GB, Del Rio M, Sparatore B, Melloni E, Pontremoli S.

Neuroscience. 1998 Feb;82(4):1021-8.

PMID:
9466426
33.

Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation.

Passalacqua M, Zicca A, Sparatore B, Patrone M, Melloni E, Pontremoli S.

FEBS Lett. 1997 Jan 6;400(3):275-9.

34.

Extracellular high-mobility group 1 protein is essential for murine erythroleukaemia cell differentiation.

Sparatore B, Passalacqua M, Patrone M, Melloni E, Pontremoli S.

Biochem J. 1996 Nov 15;320 ( Pt 1):253-6.

35.

A 6 kDa protein homologous to the N-terminus of the HMG1 protein promoting stimulation of murine erythroleukemia cell differentiation.

Sparatore B, Melloni E, Patrone M, Passalacqua M, Pontremoli S.

FEBS Lett. 1996 May 20;386(2-3):95-8.

36.

Correlation between levels of delta protein kinase C and resistance to differentiation in murine erythroleukemia cells.

Patrone M, Pessino A, Passalacqua M, Sparatore B, Melloni E, Pontremoli S.

Biochem Biophys Res Commun. 1996 Mar 7;220(1):26-30.

PMID:
8602851
37.

Antisense oligodeoxynucleotide inhibition of delta protein kinase C expression accelerates induced differentiation of murine erythroleukaemia cells.

Pessino A, Passalacqua M, Sparatore B, Patrone M, Melloni E, Pontremoli S.

Biochem J. 1995 Dec 1;312 ( Pt 2):549-54.

38.

Stratifin, a keratinocyte specific 14-3-3 protein, harbors a pleckstrin homology (PH) domain and enhances protein kinase C activity.

Dellambra E, Patrone M, Sparatore B, Negri A, Ceciliani F, Bondanza S, Molina F, Cancedda FD, De Luca M.

J Cell Sci. 1995 Nov;108 ( Pt 11):3569-79.

39.

Extracellular release of the 'differentiation enhancing factor', a HMG1 protein type, is an early step in murine erythroleukemia cell differentiation.

Melloni E, Sparatore B, Patrone M, Pessino A, Passalacqua M, Pontremoli S.

FEBS Lett. 1995 Jul 24;368(3):466-70.

40.

Identity in molecular structure between "differentiation enhancing factor" of murine erythroleukemia cells and the 30 kD heparin-binding protein of developing rat brain.

Melloni E, Sparatore B, Patrone M, Pessino A, Passalacqua M, Pontremoli S.

Biochem Biophys Res Commun. 1995 May 5;210(1):82-9.

PMID:
7741753
41.

Changes in calcium influx affect the differentiation of murine erythroleukaemia cells.

Sparatore B, Pessino A, Patrone M, Passalacqua M, Melloni E, Pontremoli S.

Biochem J. 1995 Jan 1;305 ( Pt 1):285-90.

42.

Differential expression of protein kinase C isoform genes in three murine erythroleukemia cell variants: implication for chemical induced differentiation.

Pessino A, Sparatore B, Patrone M, Passalacqua M, Melloni E, Pontremoli S.

Biochem Biophys Res Commun. 1994 Oct 28;204(2):461-7.

PMID:
7980501
43.

Modulation of the intracellular Ca(2+)-dependent proteolytic system is critically correlated with the kinetics of differentiation of murine erythroleukemia cells.

Sparatore B, Passalacqua M, Pessino A, Melloni E, Patrone M, Pontremoli S.

Eur J Biochem. 1994 Oct 1;225(1):173-8.

44.

Protein kinase C isoforms in murine erythroleukemia cells and their involvement in the differentiation process.

Patrone M, Pessino A, Passalacqua M, Sparatore B, Melloni E, Pontremoli S.

FEBS Lett. 1994 May 9;344(1):91-5.

45.

The plasma membrane calcium pump is the preferred calpain substrate within the erythrocyte.

Salamino F, Sparatore B, Melloni E, Michetti M, Viotti PL, Pontremoli S, Carafoli E.

Cell Calcium. 1994 Jan;15(1):28-35.

PMID:
8149403
46.

Differentiation of HL60 promyelocytic cells is promoted by a 'differentiation enhancing factor' produced by erythroleukemia cells.

Sparatore B, Passalacqua M, Patrone M, Pessino A, Melloni E, Pontremoli S.

FEBS Lett. 1993 Nov 15;334(2):198-202.

47.

Characterization of the biological role of murine erythroleukemia cells "differentiation enhancing factor" using antisense oligodeoxynucleotides.

Sparatore B, Patrone M, Passalacqua M, Pessino A, Falchetto R, Melloni E, Pontremoli S.

Biochem Biophys Res Commun. 1993 Jun 30;193(3):941-7.

PMID:
8323566
48.

Role of delta-PKC on the differentiation process of murine erythroleukemia cells.

Sparatore B, Pessino A, Patrone M, Passalacqua M, Melloni E, Pontremoli S.

Biochem Biophys Res Commun. 1993 May 28;193(1):220-7.

PMID:
8503911
49.

Modulation of inhibitory efficiency of rat skeletal muscle calpastatin by phosphorylation.

Pontremoli S, Viotti PL, Michetti M, Salamino F, Sparatore B, Melloni E.

Biochem Biophys Res Commun. 1992 Sep 16;187(2):751-9.

PMID:
1530632
50.

Protein kinase C mRNA levels and activity in reconstituted normal human epidermis: relationships to cell differentiation.

Gherzi R, Sparatore B, Patrone M, Sciutto A, Briata P.

Biochem Biophys Res Commun. 1992 Apr 15;184(1):283-91.

PMID:
1373611

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