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Items: 16

1.

Analgesic effects of a novel pH-dependent μ-opioid receptor agonist in models of neuropathic and abdominal pain.

Rodriguez-Gaztelumendi A, Spahn V, Labuz D, Machelska H, Stein C.

Pain. 2018 Nov;159(11):2277-2284. doi: 10.1097/j.pain.0000000000001328.

2.

Opioid receptor signaling, analgesic and side effects induced by a computationally designed pH-dependent agonist.

Spahn V, Del Vecchio G, Rodriguez-Gaztelumendi A, Temp J, Labuz D, Kloner M, Reidelbach M, Machelska H, Weber M, Stein C.

Sci Rep. 2018 Jun 12;8(1):8965. doi: 10.1038/s41598-018-27313-4.

3.

Polyglycerol-opioid conjugate produces analgesia devoid of side effects.

González-Rodríguez S, Quadir MA, Gupta S, Walker KA, Zhang X, Spahn V, Labuz D, Rodriguez-Gaztelumendi A, Schmelz M, Joseph J, Parr MK, Machelska H, Haag R, Stein C.

Elife. 2017 Jul 4;6. pii: e27081. doi: 10.7554/eLife.27081.

4.

Novel Opioid Analgesics and Side Effects.

Del Vecchio G, Spahn V, Stein C.

ACS Chem Neurosci. 2017 Aug 16;8(8):1638-1640. doi: 10.1021/acschemneuro.7b00195. Epub 2017 Jun 12.

PMID:
28603962
5.

Production of G protein-coupled receptors in an insect-based cell-free system.

Sonnabend A, Spahn V, Stech M, Zemella A, Stein C, Kubick S.

Biotechnol Bioeng. 2017 Oct;114(10):2328-2338. doi: 10.1002/bit.26346. Epub 2017 Jul 3.

6.

A nontoxic pain killer designed by modeling of pathological receptor conformations.

Spahn V, Del Vecchio G, Labuz D, Rodriguez-Gaztelumendi A, Massaly N, Temp J, Durmaz V, Sabri P, Reidelbach M, Machelska H, Weber M, Stein C.

Science. 2017 Mar 3;355(6328):966-969. doi: 10.1126/science.aai8636. Erratum in: Science. 2017 Jun 9;356(6342):.

PMID:
28254944
7.

Ankyrin-rich membrane spanning protein as a novel modulator of transient receptor potential vanilloid 1-function in nociceptive neurons.

Peter J, Kasper C, Kaufholz M, Buschow R, Isensee J, Hucho T, Herberg FW, Schwede F, Stein C, Jordt SE, Brackmann M, Spahn V.

Eur J Pain. 2017 Jul;21(6):1072-1086. doi: 10.1002/ejp.1008. Epub 2017 Feb 9.

8.

Targeting delta opioid receptors for pain treatment: drugs in phase I and II clinical development.

Spahn V, Stein C.

Expert Opin Investig Drugs. 2017 Feb;26(2):155-160. doi: 10.1080/13543784.2017.1275562. Epub 2017 Jan 2. Review.

PMID:
28001096
9.

Opioids and TRPV1 in the peripheral control of neuropathic pain--Defining a target site in the injured nerve.

Labuz D, Spahn V, Celik MÖ, Machelska H.

Neuropharmacology. 2016 Feb;101:330-40. doi: 10.1016/j.neuropharm.2015.10.003. Epub 2015 Oct 8.

PMID:
26453963
10.

Electrophysiological patch clamp assay to monitor the action of opioid receptors.

Spahn V, Nockemann D, Machelska H.

Methods Mol Biol. 2015;1230:197-211. doi: 10.1007/978-1-4939-1708-2_16.

PMID:
25293327
11.

Analysis of potassium and calcium imaging to assay the function of opioid receptors.

Spahn V, Nockemann D, Machelska H.

Methods Mol Biol. 2015;1230:187-96. doi: 10.1007/978-1-4939-1708-2_15.

PMID:
25293326
12.

Modulation of transient receptor vanilloid 1 activity by transient receptor potential ankyrin 1.

Spahn V, Stein C, Zöllner C.

Mol Pharmacol. 2014 Feb;85(2):335-44. doi: 10.1124/mol.113.088997. Epub 2013 Nov 25.

13.

Opioid withdrawal increases transient receptor potential vanilloid 1 activity in a protein kinase A-dependent manner.

Spahn V, Fischer O, Endres-Becker J, Schäfer M, Stein C, Zöllner C.

Pain. 2013 Apr;154(4):598-608. doi: 10.1016/j.pain.2012.12.026. Epub 2013 Jan 11.

PMID:
23398938
14.

Exploiting Fluorescence Lifetime Plasticity in FLIM: Target Molecule Localization in Cells and Tissues.

Boreham A, Kim TY, Spahn V, Stein C, Mundhenk L, Gruber AD, Haag R, Welker P, Licha K, Alexiev U.

ACS Med Chem Lett. 2011 Aug 9;2(10):724-8. doi: 10.1021/ml200092m. eCollection 2011 Oct 13.

15.

Salivary gland carcinosarcoma: immunohistochemical, molecular genetic and electron microscopic findings.

Götte K, Riedel F, Coy JF, Spahn V, Hörmann K.

Oral Oncol. 2000 Jul;36(4):360-4.

PMID:
10899675
16.

Functional work habits.

Spahn V, Kilpatrick HC.

J Am Dent Hyg Assoc. 1969;43(2):82-5. No abstract available.

PMID:
5252982

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