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Items: 30

1.

Amphiphilic nanoparticle delivery enhances the anticancer efficacy of a TLR7 ligand via local immune activation.

Mottas I, Bekdemir A, Cereghetti A, Spagnuolo L, Yang YS, Müller M, Irvine DJ, Stellacci F, Bourquin C.

Biomaterials. 2019 Jan;190-191:111-120. doi: 10.1016/j.biomaterials.2018.10.031. Epub 2018 Oct 25.

PMID:
30415018
2.

Immune regulation of metastasis: mechanistic insights and therapeutic opportunities.

Blomberg OS, Spagnuolo L, de Visser KE.

Dis Model Mech. 2018 Oct 24;11(10). pii: dmm036236. doi: 10.1242/dmm.036236. Review.

3.

NAB2 is a novel immune stimulator of MDA-5 that promotes a strong type I interferon response.

Oberson A, Spagnuolo L, Puddinu V, Barchet W, Rittner K, Bourquin C.

Oncotarget. 2017 Dec 15;9(5):5641-5651. doi: 10.18632/oncotarget.23725. eCollection 2018 Jan 19.

4.

Synthesized Heparan Sulfate Competitors Attenuate Pseudomonas aeruginosa Lung Infection.

Lorè NI, Veraldi N, Riva C, Sipione B, Spagnuolo L, De Fino I, Melessike M, Calzi E, Bragonzi A, Naggi A, Cigana C.

Int J Mol Sci. 2018 Jan 9;19(1). pii: E207. doi: 10.3390/ijms19010207.

5.

Arginase inhibition suppresses lung metastasis in the 4T1 breast cancer model independently of the immunomodulatory and anti-metastatic effects of VEGFR-2 blockade.

Secondini C, Coquoz O, Spagnuolo L, Spinetti T, Peyvandi S, Ciarloni L, Botta F, Bourquin C, Rüegg C.

Oncoimmunology. 2017 Apr 20;6(6):e1316437. doi: 10.1080/2162402X.2017.1316437. eCollection 2017.

6.

Rationalizing the Binding Kinetics for the Inhibition of the Burkholderia pseudomallei FabI1 Enoyl-ACP Reductase.

Neckles C, Eltschkner S, Cummings JE, Hirschbeck M, Daryaee F, Bommineni GR, Zhang Z, Spagnuolo L, Yu W, Davoodi S, Slayden RA, Kisker C, Tonge PJ.

Biochemistry. 2017 Apr 4;56(13):1865-1878. doi: 10.1021/acs.biochem.6b01048. Epub 2017 Mar 21.

7.

Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors.

Spagnuolo LA, Eltschkner S, Yu W, Daryaee F, Davoodi S, Knudson SE, Allen EK, Merino J, Pschibul A, Moree B, Thivalapill N, Truglio JJ, Salafsky J, Slayden RA, Kisker C, Tonge PJ.

J Am Chem Soc. 2017 Mar 8;139(9):3417-3429. doi: 10.1021/jacs.6b11148. Epub 2017 Feb 22.

8.

Reprogramming of TLR7 signaling enhances antitumor NK and cytotoxic T cell responses.

Hotz C, Treinies M, Mottas I, Rötzer LC, Oberson A, Spagnuolo L, Perdicchio M, Spinetti T, Herbst T, Bourquin C.

Oncoimmunology. 2016 Sep 9;5(11):e1232219. doi: 10.1080/2162402X.2016.1232219. eCollection 2016.

9.

TLR7-based cancer immunotherapy decreases intratumoral myeloid-derived suppressor cells and blocks their immunosuppressive function.

Spinetti T, Spagnuolo L, Mottas I, Secondini C, Treinies M, Rüegg C, Hotz C, Bourquin C.

Oncoimmunology. 2016 Sep 9;5(11):e1230578. doi: 10.1080/2162402X.2016.1230578. eCollection 2016.

10.

The host genetic background defines diverse immune-reactivity and susceptibility to chronic Pseudomonas aeruginosa respiratory infection.

Spagnuolo L, De Simone M, Lorè NI, De Fino I, Basso V, Mondino A, Cigana C, Bragonzi A.

Sci Rep. 2016 Nov 16;6:36924. doi: 10.1038/srep36924.

11.

IL-17A impairs host tolerance during airway chronic infection by Pseudomonas aeruginosa.

Lorè NI, Cigana C, Riva C, De Fino I, Nonis A, Spagnuolo L, Sipione B, Cariani L, Girelli D, Rossi G, Basso V, Colombo C, Mondino A, Bragonzi A.

Sci Rep. 2016 May 18;6:25937. doi: 10.1038/srep25937.

12.

Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice.

De Simone M, Spagnuolo L, Lorè NI, Cigana C, De Fino I, Broman KW, Iraqi FA, Bragonzi A.

BMC Genomics. 2016 May 11;17:351. doi: 10.1186/s12864-016-2676-4.

13.

Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections.

Cigana C, Lorè NI, Riva C, De Fino I, Spagnuolo L, Sipione B, Rossi G, Nonis A, Cabrini G, Bragonzi A.

Sci Rep. 2016 Feb 17;6:21465. doi: 10.1038/srep21465.

14.

An ordered water channel in Staphylococcus aureus FabI: unraveling the mechanism of substrate recognition and reduction.

Schiebel J, Chang A, Merget B, Bommineni GR, Yu W, Spagnuolo LA, Baxter MV, Tareilus M, Tonge PJ, Kisker C, Sotriffer CA.

Biochemistry. 2015 Mar 17;54(10):1943-55. doi: 10.1021/bi5014358. Epub 2015 Mar 3.

15.

A [(32)P]NAD(+)-based method to identify and quantitate long residence time enoyl-acyl carrier protein reductase inhibitors.

Yu W, Neckles C, Chang A, Bommineni GR, Spagnuolo L, Zhang Z, Liu N, Lai C, Truglio J, Tonge PJ.

Anal Biochem. 2015 Apr 1;474:40-9. doi: 10.1016/j.ab.2014.12.022. Epub 2015 Feb 14.

16.

Host genetic background influences the response to the opportunistic Pseudomonas aeruginosa infection altering cell-mediated immunity and bacterial replication.

De Simone M, Spagnuolo L, Lorè NI, Rossi G, Cigana C, De Fino I, Iraqi FA, Bragonzi A.

PLoS One. 2014 Sep 30;9(9):e106873. doi: 10.1371/journal.pone.0106873. eCollection 2014.

17.

Genome-wide identification of genes essential for the survival of Streptococcus pneumoniae in human saliva.

Verhagen LM, de Jonge MI, Burghout P, Schraa K, Spagnuolo L, Mennens S, Eleveld MJ, van der Gaast-de Jongh CE, Zomer A, Hermans PW, Bootsma HJ.

PLoS One. 2014 Feb 25;9(2):e89541. doi: 10.1371/journal.pone.0089541. eCollection 2014.

18.

A reappraisal of the diagnostic and therapeutic management of uncommon histologies of primary ocular adnexal lymphoma.

Ponzoni M, Govi S, Licata G, Mappa S, Giordano Resti A, Politi LS, Spagnuolo L, Di Cairano E, Doglioni C, Ferreri AJ.

Oncologist. 2013;18(7):876-84. doi: 10.1634/theoncologist.2012-0425. Epub 2013 Jun 28. Review.

19.

CDC25A protein stability represents a previously unrecognized target of HER2 signaling in human breast cancer: implication for a potential clinical relevance in trastuzumab treatment.

Brunetto E, Ferrara AM, Rampoldi F, Talarico A, Cin ED, Grassini G, Spagnuolo L, Sassi I, Ferro A, Cuorvo LV, Barbareschi M, Piccinin S, Maestro R, Pecciarini L, Doglioni C, Cangi MG.

Neoplasia. 2013 Jun;15(6):579-90.

20.

Gains of CCND3 gene in ocular adnexal MALT lymphomas: an integrated analysis.

Li ZM, Spagnuolo L, Mensah AA, Rinaldi A, Bhagat G, Zucca E, Doglioni C, Ferreri AJ, Ponzoni M, Bertoni F.

Br J Haematol. 2013 Mar;160(5):719-22. doi: 10.1111/bjh.12161. Epub 2012 Dec 13. No abstract available.

PMID:
23240690
21.

Convergent synthesis of dendrimers via the Passerini three-component reaction.

Jee JA, Spagnuolo LA, Rudick JG.

Org Lett. 2012 Jul 6;14(13):3292-5. doi: 10.1021/ol301263v. Epub 2012 Jun 15.

PMID:
22702475
22.

[Beekeeping: study of organization, general hazards assessment, pre-assessment of risk for mechanical overload using a new tool for easy application].

Ruschioni A, Montesi S, Spagnuolo LM, Rinaldi L, Fantozzi L, Fanti M.

Med Lav. 2011 Jan-Feb;102(1):70-88. Italian.

PMID:
21485487
23.

Biodegradation of semi- and non-volatile petroleum hydrocarbons in aged, contaminated soils from a sub-Arctic site: laboratory pilot-scale experiments at site temperatures.

Chang W, Dyen M, Spagnuolo L, Simon P, Whyte L, Ghoshal S.

Chemosphere. 2010 Jun;80(3):319-26. doi: 10.1016/j.chemosphere.2010.03.055. Epub 2010 May 14.

PMID:
20471057
24.
25.

Risk factors for type 2 diabetes in women attending menopause clinics in Italy: a cross-sectional study.

Di Donato P, Giulini NA, Bacchi Modena A, Cicchetti G, Comitini G, Gentile G, Cristiani P, Careccia A, Esposito E, Gualdi F, Golinelli S, Bergamini E, Masellis G, Rastelli S, Gigli C, Elia A, Marchesoni D, Sticotti F, Del Frate G, Zompicchiatti C, Marino L, Costa MR, Pinto P, Dodero D, Storace A, Spinelli G, Quaranta S, Bossi CM, Ollago A, Omodei U, Vaccari M, Luerti M, Repetti F, Zandonini G, Raspagliesi F, Dolci F, Gambarino G, De Pasquale B, Polizzotti G, Borsellino G, Alpinelli P, Natale N, Colombo D, Belloni C, Viani A, Cecchini G, Vinci GW, Samaja BA, Pasinetti E, Penotti M, Ognissanti F, Pesando P, Malanetto C, Gallo M, Dolfin G, Tartaglino P, Mossotto D, Pistoni A, Tarani A, Rattazzi PD, Rossaro D, Campanella M, Arisi E, Gamper M, Salvatores D, Bocchin E, Stellin G, Meli G, Azzini V, Tirozzi F, Buoso G, Fraioli R, Marsoni V, Cetera C, Sposetti R, Candiotto E, Pignalosa R, Del Pup L, Bellati U, Angeloni C, Buonerba M, Garzarelli S, Santilli C, Mucci M, Di Nisio Q, Cappa F, Pierangeli I, Cordone A, Falasca L, Ferrante D, Serra GB, Cirese E, Todaro PA, Romanini C, Spagnuolo L, Lanzone A, Donadio C, Fabiani M, Baldaccini E, Votano S, Bellardini P, Favale W, Monti V, Bonomo A, Boninfante CE, Pietrobattista P, Massacesi L, Donini G, Del Savio F, Palombi L, Procaccioli P, Romani A, Romagnoli G, Genazzani AR, Gambacciani M, Scarselli G, Curiel P, De Leo V, Melani A, Levi D'Ancona V, Giarrè G, Di Gioia E, Ceccarelli P, Massi GB, Cosci S, Gacci G, Cascianini A, Donati Sarti C, Bircolotti S, Pupita P, Mincigrucci M, Spadafora A, Santeufemia G, Marongiu G, Lai GR, Lai R, Dessole S, D'Andrea SA, Coppola, Chiantera A, De Placido, Arienzo R, Pastore AR, Tamburrino A, Cardone A, Colacurci N, Izzo S, Tesauro R, Pascarella A, De Silvio MG, Di Prisco L, Lauda N, Sirimarco F, Agrimi C, Casarella G, Senatore G, Ronzini S, Ruccia G, De Carlo G, Pisaturo G, Carlomagno F, Fasolino A, Fiorillo F, Sorrentino R, Ercolano VB, Panariello S, Brun A, Tropea P, Stigliano CM, Amoroso A, Vadalà P, Coco A, Galati G, Barese G, Masciari G, Pirillo P, Gioffrè T, Mastrantonio P, Cardamone A, D'Angelo N, Valentino G, Barretta R, Ferraro G, Ferruccio C, Agostinelli D, Corrado G, Scopelliti A, Schonauer S, Trojano V, Bongiovanni F, Tinelli F, Poddi ER, Scarpello F, Colonna L, Fischetti G, Doria R, Trombetta G, Cocca EB, D'Amore A, Di Masi M, Liguori R, Dimaggio A, Laneve MR, Maolo MC, Gravina G, Nacci G, Nocera F, Lupo A, Giannola C, Graziano R, Mezzatesta M, Vegna G, Giannone G, Palumbo G, Cancellieri F, Mondo A, Cordopatri A, Carrubba M, Mazzola V, Cincotta L, D'Asta S, Bono A, Li Calsi L, Cavallaro Nigro S, Schilirò S, Repici A, Gullo D, Orlando A, Specchiale F, Papotto A, Abruzzo, Basilicata, Calabria, Campania, Emilia, Romagna, Giulia FV, Lazio, Liguria, Lombardia, Marche, Molise, Piemonte, Puglia, Sardegna, Sicilia, Toscana, Adige TA, Umbria, D'Aosta V, Veneto, Massacesi A, Chiantera A, Donati Sarti C, De Aloysio P, Omodei U, Ognissanti F, Campagnoli C, Penotti M, Gambacciani A, Graziottin A, Baldi C, Colacurci N, Corrado Tonti G, Parazzini F, Chatenoud L; Gruppo di Studio Progetto Menopausa Italia.

Climacteric. 2005 Sep;8(3):287-93.

PMID:
16397927
26.

Factors associated with climacteric symptoms in women around menopause attending menopause clinics in Italy.

Di Donato P, Giulini NA, Bacchi Modena A, Cicchetti G, Comitini G, Gentile G, Cristiani P, Careccia A, Esposito E, Gualdi F, Golinelli S, Bergamini E, Masellis G, Rastelli S, Gigli C, Elia A, Marchesoni D, Sticotti F, Del Frate G, Zompicchiatti C, Marino L, Costa MR, Pinto P, Dodero D, Storace A, Spinelli G, Quaranta S, Bossi CM, Ollago A, Omodei U, Vaccari M, Luerti M, Repetti F, Zandonini G, Raspagliesi F, Dolci F, Gambarino G, De Pasquale B, Polizzotti G, Borsellino G, Alpinelli P, Natale N, Colombo D, Belloni C, Viani A, Cecchini G, Vinci GW, Samaja BA, Pasinetti E, Penotti M, Ognissanti F, Pesando P, Malanetto C, Gallo M, Dolfin G, Tartaglino P, Mossotto D, Pistoni A, Tarani A, Rattazzi PD, Rossaro D, Campanella M, Arisi E, Gamper M, Salvatores D, Bocchin E, Stellin G, Meli G, Azzini V, Tirozzi F, Buoso G, Fraioli R, Marsoni V, Cetera C, Sposetti R, Candiotto E, Sposetti R, Candiotto E, Pignalosa R, Del Pup L, Bellati U, Angeloni C, Buonerba M, Garzarelli S, Santilli C, Mucci M, Di Nisio Q, Cappa F, Pierangeli I, Cordone A, Falasca L, Ferrante D, Cirese E, Todaro PA, Spagnuolo L, Lanzone A, Donadio C, Fabiani M, Baldaccini E, Votano S, Bellardini P, Favale W, Pietrobattista V, Massacesi L, Donini G, Del Savio F, Palombi L, Procaccioli P, Romani A, Romagnoli G, Genazzani AR, Gambacciani M, Scarselli G, Curiel P, De Leo V, Melani A, Levi D'Ancona V, Giarrè G, Di Gioia E, Ceccarelli P, Massi GB, Cosci S, Gacci G, Cascianini A, Donati Sarti C, Bircolotti S, Pupita P, Mincigrucci M, Spadafora A, Santeufemia G, Marongiu G, Lai GR, Lai R, Dessole S, D'Andrea SA, Coppola, Chiantera A, De Placido, Arienzo R, Pastore AR, Tamburrino A, Cardone A, Colacurci N, Izzo S, Tesauro R, Pascarella A, De Silvio MG, Di Prisco L, Lauda N, Sirimarco F, Agrimi C, Casarella G, Senatore G, Ronzini S, Ruccia G, De Carlo G, Pisaturo G, Carlomagno F, Fasolino A, Fiorillo F, Sorrentino R, Ercolano VB, Panariello S, Brun A, Tropea P, Stigliano CM, Amoroso A, Vadalà P, Coco A, Galati G, Barese G, Masciari G, Pirillo P, Gioffrè T, Mastrantonio P, Cardamone A, D'Angelo N, Valentino G, Barretta R, Ferraro G, Ferruccio C, Agostinelli D, Corrado G, Scopelliti A, Schonauer S, Trojano V, Bongiovanni F, Tinelli F, Poddi ER, Scarpello F, Colonna L, Fischetti G, Doria R, Trombetta G, Cocca EB, D'Amore A, Di Masi M, Liguori R, Dimaggio A, Laneve MR, Maolo MC, Gravina G, Nacci G, Nocera F, Lupo A, Giannola C, Graziano R, Mezzatesta M, Vegna G, Giannone G, Palumbo G, Cancellieri F, Mondo A, Cordopatri A, Carrubba M, Mazzola V, Cincotta L, D'Asta S, Bono A, Li Calsi L, Cavallaro Nigro S, Schilirò S, Repici A, Gullo D, Orlando A, Specchiale F, Papotto A, Angeloni, D'Andrea, Stigliano, Arienzo, Di Donato, Giulini, Gigli, Todaro, Marino, Luerti, Donini, Ferrante, Dolfin, Poddi, Santeufemia, Nocera, Melani, Arisi, Mincigrucci, Salvatores, Bocchin, Massacesi A, Chiantera A, De Aloysio P, Omodei U, Ognissanti F, Campagnoli C, Penotti M, Gambacciani A, Graziottin A, Baldi C, Colacurci N, Tonti GC, Parazzini F, Chatenoud L, Donati Sarti C; Progetto Menopausa Italia Study Group.

Maturitas. 2005 Nov-Dec;52(3-4):181-9.

PMID:
16257609
27.

Total and lipid-bound serum sialic acid as markers for carcinoma of the uterine cervix.

Vivas I, Spagnuolo L, Palacios P.

Gynecol Oncol. 1992 Aug;46(2):157-62.

PMID:
1500016
28.

[A case of simultaneous intra- and extra-uterine pregnancy. Diagnostic and therapeutic considerations].

Spagnuolo L, Fiore M, Patronelli CG.

Minerva Ginecol. 1989 Jun;41(6):301-5. Italian.

PMID:
2671809
29.

[Prenatal evaluation of fetal health by integrated biophysical methods].

Spagnuolo L, Fiore M, Patronelli CG.

Minerva Ginecol. 1988 Oct;40(10):571-6. Italian. No abstract available.

PMID:
3221998
30.

The evolution and application of mechanical end-to-end anastomoses in gastrointestinal surgery.

Boorstein RI, Spagnuolo LJ.

J Am Osteopath Assoc. 1982 Feb;81(6):389-95. No abstract available.

PMID:
7068461

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