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Items: 19

1.

The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function.

Spaeth JM, Liu JH, Peters D, Guo M, Osipovich AB, Mohammadi F, Roy N, Bhushan A, Magnuson MA, Hebrok M, Wright CVE, Stein R.

Diabetes. 2019 Sep;68(9):1806-1818. doi: 10.2337/db19-0349. Epub 2019 Jun 14.

PMID:
31201281
2.

B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib.

Wilson CS, Spaeth JM, Karp J, Stocks BT, Hoopes EM, Stein RW, Moore DJ.

JCI Insight. 2019 Apr 9;5. pii: 125317. doi: 10.1172/jci.insight.125317.

3.

HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes.

Russell MA, Redick SD, Blodgett DM, Richardson SJ, Leete P, Krogvold L, Dahl-Jørgensen K, Bottino R, Brissova M, Spaeth JM, Babon JAB, Haliyur R, Powers AC, Yang C, Kent SC, Derr AG, Kucukural A, Garber MG, Morgan NG, Harlan DM.

Diabetes. 2019 May;68(5):988-1001. doi: 10.2337/db18-0686. Epub 2019 Mar 4.

4.

Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.

Park MJ, Shen H, Spaeth JM, Tolvanen JH, Failor C, Knudtson JF, McLaughlin J, Halder SK, Yang Q, Bulun SE, Al-Hendy A, Schenken RS, Aaltonen LA, Boyer TG.

J Biol Chem. 2018 Mar 30;293(13):4870-4882. doi: 10.1074/jbc.RA118.001725. Epub 2018 Feb 13.

5.

Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning.

Spaeth JM, Gupte M, Perelis M, Yang YP, Cyphert H, Guo S, Liu JH, Guo M, Bass J, Magnuson MA, Wright C, Stein R.

Diabetes. 2017 Nov;66(11):2830-2839. doi: 10.2337/db16-1516. Epub 2017 Jul 13.

6.

Impact of Pdx1-associated chromatin modifiers on islet β-cells.

Spaeth JM, Walker EM, Stein R.

Diabetes Obes Metab. 2016 Sep;18 Suppl 1:123-7. doi: 10.1111/dom.12730. Review.

7.

The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice.

Spaeth JM, Hunter CS, Bonatakis L, Guo M, French CA, Slack I, Hara M, Fisher SE, Ferrer J, Morrisey EE, Stanger BZ, Stein R.

Diabetologia. 2015 Aug;58(8):1836-44. doi: 10.1007/s00125-015-3635-3. Epub 2015 May 29.

8.

Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.

Turunen M, Spaeth JM, Keskitalo S, Park MJ, Kivioja T, Clark AD, Mäkinen N, Gao F, Palin K, Nurkkala H, Vähärautio A, Aavikko M, Kämpjärvi K, Vahteristo P, Kim CA, Aaltonen LA, Varjosalo M, Taipale J, Boyer TG.

Cell Rep. 2014 May 8;7(3):654-60. doi: 10.1016/j.celrep.2014.03.047. Epub 2014 Apr 18.

9.

MED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signaling.

Zhou H, Spaeth JM, Kim NH, Xu X, Friez MJ, Schwartz CE, Boyer TG.

Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19763-8. doi: 10.1073/pnas.1121120109. Epub 2012 Oct 22.

10.

Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet.

Krebs P, Fan W, Chen YH, Tobita K, Downes MR, Wood MR, Sun L, Li X, Xia Y, Ding N, Spaeth JM, Moresco EM, Boyer TG, Lo CW, Yen J, Evans RM, Beutler B.

Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19678-82. doi: 10.1073/pnas.1117835108. Epub 2011 Nov 21.

11.

Mediator and human disease.

Spaeth JM, Kim NH, Boyer TG.

Semin Cell Dev Biol. 2011 Sep;22(7):776-87. doi: 10.1016/j.semcdb.2011.07.024. Epub 2011 Aug 4. Review.

12.

Measurement of Cu(II) copper defect dipoles in ferroelectric PbTiO3 using electron-nuclear double resonance.

Garipov RR, Spaeth JM, Keeble DJ.

Phys Rev Lett. 2008 Dec 12;101(24):247604. Epub 2008 Dec 12.

PMID:
19113666
13.

High-field optically detected EPR and ENDOR of semiconductor defects using W-band microwave Fabry-Pérot resonators.

Spaeth JM, Tkach I, Greulich-Weber S, Overhof H.

Magn Reson Chem. 2005 Nov;43 Spec no.:S153-65.

PMID:
16235193
14.

Ni2+ ions in RbCdF3: An EPR study in the cubic and tetragonal phases.

Alonso PJ, Alcalá R, Spaeth JM.

Phys Rev B Condens Matter. 1990 Jun 1;41(16):10902-10905. No abstract available.

PMID:
9993508
15.

Arsenic antisite defects in AlxGa1-xAs observed by luminescence-detected electron-spin resonance.

Fockele M, Meyer BK, Spaeth JM, Heuken M, Heime K.

Phys Rev B Condens Matter. 1989 Jul 15;40(3):2001-2004. No abstract available.

PMID:
9992072
16.

Unification of the properties of the EL2 defect in GaAs.

Hoinkis M, Weber ER, Walukiewicz W, Lagowski J, Matsui M, Gatos HC, Meyer BK, Spaeth JM.

Phys Rev B Condens Matter. 1989 Mar 15;39(8):5538-5541. No abstract available.

PMID:
9948957
17.

Structure of a (RhCl6)4- defect in AgCl.

Olm MT, Niklas JR, Spaeth JM, Symons MC.

Phys Rev B Condens Matter. 1988 Sep 1;38(7):4343-4351. No abstract available.

PMID:
9946820
18.

Theory of indirect hyperfine interactions of oxygen-aluminum defects in ionic crystals.

Adrian FJ, Jette AN, Spaeth JM.

Phys Rev B Condens Matter. 1985 Mar 15;31(6):3923-3931. No abstract available.

PMID:
9936292
19.

Sensitivity enhancement in ESR/ENDOR spectrometers by use of microwave amplifiers.

Hoentzsch C, Niklas JR, Spaeth JM.

Rev Sci Instrum. 1978 Aug;49(8):1100.

PMID:
18699261

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