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Items: 1 to 50 of 61

1.

Large-cage assessment of a transgenic sex-ratio distortion strain on populations of an African malaria vector.

Facchinelli L, North AR, Collins CM, Menichelli M, Persampieri T, Bucci A, Spaccapelo R, Crisanti A, Benedict MQ.

Parasit Vectors. 2019 Feb 6;12(1):70. doi: 10.1186/s13071-019-3289-y.

2.

Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents.

Brindisi M, Ulivieri C, Alfano G, Gemma S, de Asís Balaguer F, Khan T, Grillo A, Chemi G, Menchon G, Prota AE, Olieric N, Lucena-Agell D, Barasoain I, Diaz JF, Nebbioso A, Conte M, Lopresti L, Magnano S, Amet R, Kinsella P, Zisterer DM, Ibrahim O, O'Sullivan J, Morbidelli L, Spaccapelo R, Baldari C, Butini S, Novellino E, Campiani G, Altucci L, Steinmetz MO, Brogi S.

Eur J Med Chem. 2019 Jan 15;162:290-320. doi: 10.1016/j.ejmech.2018.11.004. Epub 2018 Nov 3.

PMID:
30448418
3.

Estimating bacteria diversity in different organs of nine species of mosquito by next generation sequencing.

Mancini MV, Damiani C, Accoti A, Tallarita M, Nunzi E, Cappelli A, Bozic J, Catanzani R, Rossi P, Valzano M, Serrao A, Ricci I, Spaccapelo R, Favia G.

BMC Microbiol. 2018 Oct 4;18(1):126. doi: 10.1186/s12866-018-1266-9.

4.

Anticarcinogenic activities of sulforaphane are influenced by Nerve Growth Factor in human melanoma A375 cells.

Arcidiacono P, Stabile AM, Ragonese F, Pistilli A, Calvieri S, Bottoni U, Crisanti A, Spaccapelo R, Rende M.

Food Chem Toxicol. 2018 Mar;113:154-161. doi: 10.1016/j.fct.2018.01.051. Epub 2018 Jan 31.

PMID:
29407470
5.

Antitumor activity and expression profiles of genes induced by sulforaphane in human melanoma cells.

Arcidiacono P, Ragonese F, Stabile A, Pistilli A, Kuligina E, Rende M, Bottoni U, Calvieri S, Crisanti A, Spaccapelo R.

Eur J Nutr. 2018 Oct;57(7):2547-2569. doi: 10.1007/s00394-017-1527-7. Epub 2017 Sep 1.

6.

Correction: Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole.

Fougère A, Jackson AP, Bechtsi DP, Braks JA, Annoura T, Fonager J, Spaccapelo R, Ramesar J, Chevalley-Maurel S, Klop O, van der Laan AM, Tanke HJ, Kocken CH, Pasini EM, Khan SM, Böhme U, van Ooij C, Otto TD, Janse CJ, Franke-Fayard B.

PLoS Pathog. 2017 Jan 17;13(1):e1006128. doi: 10.1371/journal.ppat.1006128. eCollection 2017 Jan.

7.

Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria.

Capuccini B, Lin J, Talavera-López C, Khan SM, Sodenkamp J, Spaccapelo R, Langhorne J.

Sci Rep. 2016 Dec 19;6:39258. doi: 10.1038/srep39258.

8.

Release of Plasmodium sporozoites requires proteins with histone-fold dimerization domains.

Currà C, Gessmann R, Pace T, Picci L, Peruzzi G, Varamogianni-Mamatsi V, Spanos L, Garcia CR, Spaccapelo R, Ponzi M, Siden-Kiamos I.

Nat Commun. 2016 Dec 16;7:13846. doi: 10.1038/ncomms13846.

9.

Correction: Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole.

Fougère A, Jackson AP, Paraskevi Bechtsi D, Braks JA, Annoura T, Fonager J, Spaccapelo R, Ramesar J, Chevalley-Maurel S, Klop O, van der Laan AM, Tanke HJ, Kocken CH, Pasini EM, Khan SM, Böhme U, van Ooij C, Otto TD, Janse CJ, Franke-Fayard B.

PLoS Pathog. 2016 Dec 14;12(12):e1006107. doi: 10.1371/journal.ppat.1006107. eCollection 2016 Dec.

10.

Variant Exported Blood-Stage Proteins Encoded by Plasmodium Multigene Families Are Expressed in Liver Stages Where They Are Exported into the Parasitophorous Vacuole.

Fougère A, Jackson AP, Bechtsi DP, Braks JA, Annoura T, Fonager J, Spaccapelo R, Ramesar J, Chevalley-Maurel S, Klop O, van der Laan AM, Tanke HJ, Kocken CH, Pasini EM, Khan SM, Böhme U, van Ooij C, Otto TD, Janse CJ, Franke-Fayard B.

PLoS Pathog. 2016 Nov 16;12(11):e1005917. doi: 10.1371/journal.ppat.1005917. eCollection 2016 Nov. Erratum in: PLoS Pathog. 2016 Dec 14;12 (12 ):e1006107. PLoS Pathog. 2017 Jan 17;13(1):e1006128.

11.

Comparison of Model Predictions and Laboratory Observations of Transgene Frequencies in Continuously-Breeding Mosquito Populations.

Valerio L, North A, Collins CM, Mumford JD, Facchinelli L, Spaccapelo R, Benedict MQ.

Insects. 2016 Sep 22;7(4). pii: E47. doi: 10.3390/insects7040047.

12.

Human CD8+ T cells mediate protective immunity induced by a human malaria vaccine in human immune system mice.

Li X, Huang J, Zhang M, Funakoshi R, Sheetij D, Spaccapelo R, Crisanti A, Nussenzweig V, Nussenzweig RS, Tsuji M.

Vaccine. 2016 Aug 31;34(38):4501-4506. doi: 10.1016/j.vaccine.2016.08.006. Epub 2016 Aug 5.

13.

Development of novel cyclic peptides as pro-apoptotic agents.

Brindisi M, Maramai S, Brogi S, Fanigliulo E, Butini S, Guarino E, Casagni A, Lamponi S, Bonechi C, Nathwani SM, Finetti F, Ragonese F, Arcidiacono P, Campiglia P, Valenti S, Novellino E, Spaccapelo R, Morbidelli L, Zisterer DM, Williams CD, Donati A, Baldari C, Campiani G, Ulivieri C, Gemma S.

Eur J Med Chem. 2016 Jul 19;117:301-20. doi: 10.1016/j.ejmech.2016.04.001. Epub 2016 Apr 5.

PMID:
27150036
14.

Paratransgenesis to control malaria vectors: a semi-field pilot study.

Mancini MV, Spaccapelo R, Damiani C, Accoti A, Tallarita M, Petraglia E, Rossi P, Cappelli A, Capone A, Peruzzi G, Valzano M, Picciolini M, Diabaté A, Facchinelli L, Ricci I, Favia G.

Parasit Vectors. 2016 Mar 10;9:140. doi: 10.1186/s13071-016-1427-3.

15.

A draft genome sequence of an invasive mosquito: an Italian Aedes albopictus.

Dritsou V, Topalis P, Windbichler N, Simoni A, Hall A, Lawson D, Hinsley M, Hughes D, Napolioni V, Crucianelli F, Deligianni E, Gasperi G, Gomulski LM, Savini G, Manni M, Scolari F, Malacrida AR, Arcà B, Ribeiro JM, Lombardo F, Saccone G, Salvemini M, Moretti R, Aprea G, Calvitti M, Picciolini M, Papathanos PA, Spaccapelo R, Favia G, Crisanti A, Louis C.

Pathog Glob Health. 2015 Jul;109(5):207-20. doi: 10.1179/2047773215Y.0000000031. Epub 2015 Sep 14.

16.

Stimulating Anopheles gambiae swarms in the laboratory: application for behavioural and fitness studies.

Facchinelli L, Valerio L, Lees RS, Oliva CF, Persampieri T, Collins CM, Crisanti A, Spaccapelo R, Benedict MQ.

Malar J. 2015 Jul 15;14:271. doi: 10.1186/s12936-015-0792-2.

17.

Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance.

Lin JW, Spaccapelo R, Schwarzer E, Sajid M, Annoura T, Deroost K, Ravelli RB, Aime E, Capuccini B, Mommaas-Kienhuis AM, O'Toole T, Prins F, Franke-Fayard BM, Ramesar J, Chevalley-Maurel S, Kroeze H, Koster AJ, Tanke HJ, Crisanti A, Langhorne J, Arese P, Van den Steen PE, Janse CJ, Khan SM.

J Exp Med. 2015 Jun 1;212(6):893-903. doi: 10.1084/jem.20141731. Epub 2015 May 4.

18.

IgG2 antibodies against a clinical grade Plasmodium falciparum CSP vaccine antigen associate with protection against transgenic sporozoite challenge in mice.

Schwenk R, DeBot M, Porter M, Nikki J, Rein L, Spaccapelo R, Crisanti A, Wightman PD, Ockenhouse CF, Dutta S.

PLoS One. 2014 Oct 24;9(10):e111020. doi: 10.1371/journal.pone.0111020. eCollection 2014.

19.

Protective or pathogenic effects of vascular endothelial growth factor (VEGF) as potential biomarker in cerebral malaria.

Canavese M, Spaccapelo R.

Pathog Glob Health. 2014 Mar;108(2):67-75. doi: 10.1179/2047773214Y.0000000130. Epub 2014 Mar 7. Review.

20.

CluGene: A Bioinformatics Framework for the Identification of Co-Localized, Co-Expressed and Co-Regulated Genes Aimed at the Investigation of Transcriptional Regulatory Networks from High-Throughput Expression Data.

Dottorini T, Palladino P, Senin N, Persampieri T, Spaccapelo R, Crisanti A.

PLoS One. 2013 Jun 18;8(6):e66196. doi: 10.1371/journal.pone.0066196. Print 2013.

21.

Evidence of tRNA cleavage in apicomplexan parasites: Half-tRNAs as new potential regulatory molecules of Toxoplasma gondii and Plasmodium berghei.

Galizi R, Spano F, Giubilei MA, Capuccini B, Magini A, Urbanelli L, Ogawa T, Dubey JP, Spaccapelo R, Emiliani C, Di Cristina M.

Mol Biochem Parasitol. 2013 Apr;188(2):99-108. doi: 10.1016/j.molbiopara.2013.03.003. Epub 2013 Apr 1.

PMID:
23557708
22.

Transgenic parasites stably expressing full-length Plasmodium falciparum circumsporozoite protein as a model for vaccine down-selection in mice using sterile protection as an endpoint.

Porter MD, Nicki J, Pool CD, DeBot M, Illam RM, Brando C, Bozick B, De La Vega P, Angra D, Spaccapelo R, Crisanti A, Murphy JR, Bennett JW, Schwenk RJ, Ockenhouse CF, Dutta S.

Clin Vaccine Immunol. 2013 Jun;20(6):803-10. doi: 10.1128/CVI.00066-13. Epub 2013 Mar 27.

23.

Silencing of the Hsf gene, the transcriptional regulator of A. gambiae male accessory glands, inhibits the formation of the mating plug in mated females and disrupts their monogamous behaviour.

Dottorini T, Persampieri T, Palladino P, Spaccapelo R, Crisanti A.

Pathog Glob Health. 2012 Nov;106(7):405-12. doi: 10.1179/2047773212Y.0000000058.

24.

Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins.

Pasini EM, Braks JA, Fonager J, Klop O, Aime E, Spaccapelo R, Otto TD, Berriman M, Hiss JA, Thomas AW, Mann M, Janse CJ, Kocken CH, Franke-Fayard B.

Mol Cell Proteomics. 2013 Feb;12(2):426-48. doi: 10.1074/mcp.M112.021238. Epub 2012 Nov 28.

25.

Protective antibody and CD8+ T-cell responses to the Plasmodium falciparum circumsporozoite protein induced by a nanoparticle vaccine.

Kaba SA, McCoy ME, Doll TA, Brando C, Guo Q, Dasgupta D, Yang Y, Mittelholzer C, Spaccapelo R, Crisanti A, Burkhard P, Lanar DE.

PLoS One. 2012;7(10):e48304. doi: 10.1371/journal.pone.0048304. Epub 2012 Oct 29.

26.

Regulation of Anopheles gambiae male accessory gland genes influences postmating response in female.

Dottorini T, Persampieri T, Palladino P, Baker DA, Spaccapelo R, Senin N, Crisanti A.

FASEB J. 2013 Jan;27(1):86-97. doi: 10.1096/fj.12-219444. Epub 2012 Sep 20.

PMID:
22997226
27.

Bioluminescence imaging of P. berghei Schizont sequestration in rodents.

Braks J, Aime E, Spaccapelo R, Klop O, Janse CJ, Franke-Fayard B.

Methods Mol Biol. 2013;923:353-68.

PMID:
22990791
28.

Roles of the amino terminal region and repeat region of the Plasmodium berghei circumsporozoite protein in parasite infectivity.

Aldrich C, Magini A, Emiliani C, Dottorini T, Bistoni F, Crisanti A, Spaccapelo R.

PLoS One. 2012;7(2):e32524. doi: 10.1371/journal.pone.0032524. Epub 2012 Feb 29.

29.

Disruption of plasmepsin-4 and merozoites surface protein-7 genes in Plasmodium berghei induces combined virulence-attenuated phenotype.

Spaccapelo R, Aime E, Caterbi S, Arcidiacono P, Capuccini B, Di Cristina M, Dottorini T, Rende M, Bistoni F, Crisanti A.

Sci Rep. 2011;1:39. doi: 10.1038/srep00039. Epub 2011 Jul 18.

30.

An antigen microarray immunoassay for multiplex screening of mouse monoclonal antibodies.

Di Cristina M, Nunziangeli L, Giubilei MA, Capuccini B, d'Episcopo L, Mazzoleni G, Baldracchini F, Spaccapelo R, Crisanti A.

Nat Protoc. 2010 Dec;5(12):1932-44. doi: 10.1038/nprot.2010.161. Epub 2010 Nov 10.

PMID:
21127487
31.

Plasmepsin 4-deficient Plasmodium berghei are virulence attenuated and induce protective immunity against experimental malaria.

Spaccapelo R, Janse CJ, Caterbi S, Franke-Fayard B, Bonilla JA, Syphard LM, Di Cristina M, Dottorini T, Savarino A, Cassone A, Bistoni F, Waters AP, Dame JB, Crisanti A.

Am J Pathol. 2010 Jan;176(1):205-17. doi: 10.2353/ajpath.2010.090504. Epub 2009 Dec 17.

32.

A multifunctional, synthetic Gaussia princeps luciferase reporter for live imaging of Candida albicans infections.

Enjalbert B, Rachini A, Vediyappan G, Pietrella D, Spaccapelo R, Vecchiarelli A, Brown AJ, d'Enfert C.

Infect Immun. 2009 Nov;77(11):4847-58. doi: 10.1128/IAI.00223-09. Epub 2009 Aug 17.

33.

Mobilizing agents enhance fungal degradation of polycyclic aromatic hydrocarbons and affect diversity of indigenous bacteria in soil.

Leonardi V, Giubilei MA, Federici E, Spaccapelo R, Sasek V, Novotny C, Petruccioli M, D'Annibale A.

Biotechnol Bioeng. 2008 Oct 1;101(2):273-85. doi: 10.1002/bit.21909.

PMID:
18727031
34.

Temporal and spatial distribution of Toxoplasma gondii differentiation into Bradyzoites and tissue cyst formation in vivo.

Di Cristina M, Marocco D, Galizi R, Proietti C, Spaccapelo R, Crisanti A.

Infect Immun. 2008 Aug;76(8):3491-501. doi: 10.1128/IAI.00254-08. Epub 2008 May 27.

35.

Addition of allochthonous fungi to a historically contaminated soil affects both remediation efficiency and bacterial diversity.

Federici E, Leonardi V, Giubilei MA, Quaratino D, Spaccapelo R, D'Annibale A, Petruccioli M.

Appl Microbiol Biotechnol. 2007 Nov;77(1):203-11. Epub 2007 Sep 6.

PMID:
17823794
36.

Function of region I and II adhesive motifs of Plasmodium falciparum circumsporozoite protein in sporozoite motility and infectivity.

Tewari R, Spaccapelo R, Bistoni F, Holder AA, Crisanti A.

J Biol Chem. 2002 Dec 6;277(49):47613-8. Epub 2002 Sep 18.

37.

Myosin A expressions in sporogonic stages of Plasmodium.

Margos G, Sidén-Kiamos I, Fowler RE, Gillman TR, Spaccapelo R, Lycett G, Vlachou D, Papagiannakis G, Eling WM, Mitchell GH, Louis C.

Mol Biochem Parasitol. 2000 Dec;111(2):465-9. No abstract available.

PMID:
11163454
38.

Two conserved amino acid motifs mediate protein targeting to the micronemes of the apicomplexan parasite Toxoplasma gondii.

Di Cristina M, Spaccapelo R, Soldati D, Bistoni F, Crisanti A.

Mol Cell Biol. 2000 Oct;20(19):7332-41.

39.

Structure-function analysis of malaria proteins by gene targeting--a response.

Wengelnik K, Spaccapelo R, Naitza S, Crisanti A.

Parasitol Today. 2000 Jun;16(6):224-5. No abstract available.

PMID:
10827425
40.

The A-domain and the thrombospondin-related motif of Plasmodium falciparum TRAP are implicated in the invasion process of mosquito salivary glands.

Wengelnik K, Spaccapelo R, Naitza S, Robson KJ, Janse CJ, Bistoni F, Waters AP, Crisanti A.

EMBO J. 1999 Oct 1;18(19):5195-204.

41.

Thrombospondin-related adhesive protein (TRAP) of Plasmodium berghei and parasite motility.

Spaccapelo R, Naitza S, Robson KJ, Crisanti A.

Lancet. 1997 Aug 2;350(9074):335. No abstract available.

PMID:
9251640
42.

Neutrophil production of IL-12 and IL-10 in candidiasis and efficacy of IL-12 therapy in neutropenic mice.

Romani L, Mencacci A, Cenci E, Spaccapelo R, Del Sero G, Nicoletti I, Trinchieri G, Bistoni F, Puccetti P.

J Immunol. 1997 Jun 1;158(11):5349-56.

PMID:
9164955
43.

Early T cell unresponsiveness in mice with candidiasis and reversal by IL-2: effect on T helper cell development.

Spaccapelo R, Del Sero G, Mosci P, Bistoni F, Romani L.

J Immunol. 1997 Mar 1;158(5):2294-302.

PMID:
9036977
44.

CD4+ T-helper-cell responses in mice with low-level Candida albicans infection.

Mencacci A, Spaccapelo R, Del Sero G, Enssle KH, Cassone A, Bistoni F, Romani L.

Infect Immun. 1996 Dec;64(12):4907-14.

45.

Neutrophils producing interleukin-10 antagonize the effect of interleukin-12 in mice with candidiasis.

Mencacci A, Cenci E, Spaccapelo R, Tonnetti L, del Sero G, d'Ostiani CF, Bistoni F, Romani L.

Ann N Y Acad Sci. 1996 Oct 31;795:394-6. No abstract available.

PMID:
8958965
46.

Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans.

Romani L, Mencacci A, Cenci E, Spaccapelo R, Toniatti C, Puccetti P, Bistoni F, Poli V.

J Exp Med. 1996 Apr 1;183(4):1345-55.

47.

IL12 in Candida albicans infections.

Romani L, Bistoni F, Mencacci A, Cenci E, Spaccapelo R, Puccetti P.

Res Immunol. 1995 Sep-Oct;146(7-8):532-8. Review. No abstract available.

PMID:
8839158
48.

TGF-beta is important in determining the in vivo patterns of susceptibility or resistance in mice infected with Candida albicans.

Spaccapelo R, Romani L, Tonnetti L, Cenci E, Mencacci A, Del Sero G, Tognellini R, Reed SG, Puccetti P, Bistoni F.

J Immunol. 1995 Aug 1;155(3):1349-60.

PMID:
7636200
49.

Interleukin-4 and -10 exacerbate candidiasis in mice.

Tonnetti L, Spaccapelo R, Cenci E, Mencacci A, Puccetti P, Coffman RL, Bistoni F, Romani L.

Eur J Immunol. 1995 Jun;25(6):1559-65.

PMID:
7614983
50.

T helper cell type 1 (Th1)- and Th2-like responses are present in mice with gastric candidiasis but protective immunity is associated with Th1 development.

Cenci E, Mencacci A, Spaccapelo R, Tonnetti L, Mosci P, Enssle KH, Puccetti P, Romani L, Bistoni F.

J Infect Dis. 1995 May;171(5):1279-88.

PMID:
7751704

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