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Items: 1 to 50 of 62

1.

Reproducibility of nasal allergen challenge responses in adults with allergic rhinitis.

Pantin CT, Southworth T, Wetzel K, Singh D.

Clin Pharmacol. 2019 May 13;11:67-76. doi: 10.2147/CPAA.S184404. eCollection 2019.

2.

High frequency of infection of lung cancer patients with the parasite Toxoplasma gondii.

Bajnok J, Tarabulsi M, Carlin H, Bown K, Southworth T, Dungwa J, Singh D, Lun ZR, Smyth L, Hide G.

ERJ Open Res. 2019 May 28;5(2). pii: 00143-2018. doi: 10.1183/23120541.00143-2018. eCollection 2019 Apr.

3.

Distal Femoral Osteotomy and Lateral Meniscus Allograft Transplant.

Leong NL, Southworth TM, Cole BJ.

Clin Sports Med. 2019 Jul;38(3):387-399. doi: 10.1016/j.csm.2019.02.007. Review.

PMID:
31079770
4.

Prêt-à-porter nanoYESα and nanoYESβ bioluminescent cell biosensors for ultrarapid and sensitive screening of endocrine-disrupting chemicals.

Lopreside A, Calabretta MM, Montali L, Ferri M, Tassoni A, Branchini BR, Southworth T, D'Elia M, Roda A, Michelini E.

Anal Bioanal Chem. 2019 Apr 10. doi: 10.1007/s00216-019-01805-2. [Epub ahead of print]

PMID:
30972468
5.

Editorial Commentary: Fresh-Frozen Meniscal Allografts-Cold Does Not Always Cause Shrinkage.

Cole BJ, Naveen NB, Southworth TM, Liu JN.

Arthroscopy. 2018 Dec;34(12):3224-3225. doi: 10.1016/j.arthro.2018.08.008.

PMID:
30509432
6.

Orthobiologics for Focal Articular Cartilage Defects.

Southworth TM, Naveen NB, Nwachukwu BU, Cole BJ, Frank RM.

Clin Sports Med. 2019 Jan;38(1):109-122. doi: 10.1016/j.csm.2018.09.001. Review.

PMID:
30466717
7.

The Use of Platelet-Rich Plasma in Symptomatic Knee Osteoarthritis.

Southworth TM, Naveen NB, Tauro TM, Leong NL, Cole BJ.

J Knee Surg. 2019 Jan;32(1):37-45. doi: 10.1055/s-0038-1675170. Epub 2018 Nov 13. Review.

PMID:
30423591
8.

Preservation of Knee Articular Cartilage.

Redondo ML, Naveen NB, Liu JN, Tauro TM, Southworth TM, Cole BJ.

Sports Med Arthrosc Rev. 2018 Dec;26(4):e23-e30. doi: 10.1097/JSA.0000000000000226. Review.

PMID:
30395060
9.

Smartphone-based multicolor bioluminescent 3D spheroid biosensors for monitoring inflammatory activity.

Michelini E, Calabretta MM, Cevenini L, Lopreside A, Southworth T, Fontaine DM, Simoni P, Branchini BR, Roda A.

Biosens Bioelectron. 2019 Jan 1;123:269-277. doi: 10.1016/j.bios.2018.09.012. Epub 2018 Sep 4.

PMID:
30227987
10.

Anti-inflammatory effects of the phosphodiesterase type 4 inhibitor CHF6001 on bronchoalveolar lavage lymphocytes from asthma patients.

Southworth T, Kaur M, Hodgson L, Facchinetti F, Villetti G, Civelli M, Singh D.

Cytokine. 2019 Jan;113:68-73. doi: 10.1016/j.cyto.2018.06.007. Epub 2018 Jun 19.

PMID:
29934047
11.

The reproducibility of COPD blood eosinophil counts.

Southworth T, Beech G, Foden P, Kolsum U, Singh D.

Eur Respir J. 2018 Jul 27;52(1). pii: 1800427. doi: 10.1183/13993003.00427-2018. Print 2018 Jul. No abstract available.

PMID:
29724922
12.

A Firefly Luciferase Dual Color Bioluminescence Reporter Assay Using Two Substrates To Simultaneously Monitor Two Gene Expression Events.

Branchini BR, Southworth TL, Fontaine DM, Kohrt D, Florentine CM, Grossel MJ.

Sci Rep. 2018 Apr 16;8(1):5990. doi: 10.1038/s41598-018-24278-2.

13.

PI3K, p38 and JAK/STAT signalling in bronchial tissue from patients with asthma following allergen challenge.

Southworth T, Mason S, Bell A, Ramis I, Calbet M, Domenech A, Prats N, Miralpeix M, Singh D.

Biomark Res. 2018 Apr 11;6:14. doi: 10.1186/s40364-018-0128-9. eCollection 2018.

14.

CRTH2 antagonists in asthma: current perspectives.

Singh D, Ravi A, Southworth T.

Clin Pharmacol. 2017 Dec 15;9:165-173. doi: 10.2147/CPAA.S119295. eCollection 2017. Review.

15.

Red-emitting chimeric firefly luciferase for in vivo imaging in low ATP cellular environments.

Branchini BR, Southworth TL, Fontaine DM, Kohrt D, Welcome FS, Florentine CM, Henricks ER, DeBartolo DB, Michelini E, Cevenini L, Roda A, Grossel MJ.

Anal Biochem. 2017 Oct 1;534:36-39. doi: 10.1016/j.ab.2017.07.001. Epub 2017 Jul 4.

16.

An investigation of the anti-inflammatory effects and a potential biomarker of PI3Kδ inhibition in COPD T cells.

Khan A, Southworth T, Worsley S, Sriskantharajah S, Amour A, Hessel EM, Singh D.

Clin Exp Pharmacol Physiol. 2017 Sep;44(9):932-940. doi: 10.1111/1440-1681.12784.

PMID:
28508433
17.

Pulmonary inflammation in patients with chronic obstructive pulmonary disease with higher blood eosinophil counts.

Kolsum U, Damera G, Pham TH, Southworth T, Mason S, Karur P, Newbold P, Singh D.

J Allergy Clin Immunol. 2017 Oct;140(4):1181-1184.e7. doi: 10.1016/j.jaci.2017.04.027. Epub 2017 May 12. No abstract available.

PMID:
28506852
18.

Clinical characteristics of eosinophilic COPD versus COPD patients with a history of asthma.

Kolsum U, Ravi A, Hitchen P, Maddi S, Southworth T, Singh D.

Respir Res. 2017 Apr 26;18(1):73. doi: 10.1186/s12931-017-0559-0.

19.

A Highly Sensitive Biosensor for ATP Using a Chimeric Firefly Luciferase.

Branchini BR, Southworth TL.

Methods Enzymol. 2017;589:351-364. doi: 10.1016/bs.mie.2017.01.004. Epub 2017 Feb 20.

PMID:
28336069
20.

Bioluminescence Imaging of Spheroids for High-throughput Longitudinal Studies on 3D Cell Culture Models.

Cevenini L, Calabretta MM, Lopreside A, Branchini BR, Southworth TL, Michelini E, Roda A.

Photochem Photobiol. 2017 Mar;93(2):531-535. doi: 10.1111/php.12718. Epub 2017 Feb 28.

PMID:
28084029
21.

Leukotriene B4 levels in sputum from asthma patients.

Higham A, Cadden P, Southworth T, Rossall M, Kolsum U, Lea S, Knowles R, Singh D.

ERJ Open Res. 2016 Oct 26;2(4). pii: 00088-2015. doi: 10.1183/23120541.00088-2015. eCollection 2016 Oct.

22.

Cloning of the Orange Light-Producing Luciferase from Photinus scintillans-A New Proposal on how Bioluminescence Color is Determined.

Branchini BR, Southworth TL, Fontaine DM, Murtiashaw MH, McGurk A, Talukder MH, Qureshi R, Yetil D, Sundlov JA, Gulick AM.

Photochem Photobiol. 2017 Mar;93(2):479-485. doi: 10.1111/php.12671. Epub 2017 Jan 18.

PMID:
27861940
23.

Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients.

Southworth T, Plumb J, Gupta V, Pearson J, Ramis I, Lehner MD, Miralpeix M, Singh D.

Respir Res. 2016 Oct 4;17(1):124.

24.

Cloning of the Blue Ghost (Phausis reticulata) Luciferase Reveals a Glowing Source of Green Light.

Branchini BR, Southworth TL, Salituro LJ, Fontaine DM, Oba Y.

Photochem Photobiol. 2017 Mar;93(2):473-478. doi: 10.1111/php.12649. Epub 2016 Nov 10.

PMID:
27696431
25.

The effect of phosphatidylinositol-3 kinase inhibition on matrix metalloproteinase-9 and reactive oxygen species release from chronic obstructive pulmonary disease neutrophils.

Gupta V, Khan A, Higham A, Lemon J, Sriskantharajah S, Amour A, Hessel EM, Southworth T, Singh D.

Int Immunopharmacol. 2016 Jun;35:155-162. doi: 10.1016/j.intimp.2016.03.027. Epub 2016 Apr 16.

PMID:
27049289
26.

The effects of corticosteroids on COPD lung macrophages: a pooled analysis.

Higham A, Booth G, Lea S, Southworth T, Plumb J, Singh D.

Respir Res. 2015 Aug 20;16:98. doi: 10.1186/s12931-015-0260-0.

27.

Different inhaled allergen challenge models give reproducible results.

Lee WY, Southworth T, Singh D.

Pulm Pharmacol Ther. 2015 Aug;33:57-8. doi: 10.1016/j.pupt.2015.06.005. Epub 2015 Jun 30. No abstract available.

PMID:
26141015
28.

Experimental Support for a Single Electron-Transfer Oxidation Mechanism in Firefly Bioluminescence.

Branchini BR, Behney CE, Southworth TL, Fontaine DM, Gulick AM, Vinyard DJ, Brudvig GW.

J Am Chem Soc. 2015 Jun 24;137(24):7592-5. doi: 10.1021/jacs.5b03820. Epub 2015 Jun 12.

PMID:
26057379
29.

An enhanced chimeric firefly luciferase-inspired enzyme for ATP detection and bioluminescence reporter and imaging applications.

Branchini BR, Southworth TL, Fontaine DM, Kohrt D, Talukder M, Michelini E, Cevenini L, Roda A, Grossel MJ.

Anal Biochem. 2015 Sep 1;484:148-53. doi: 10.1016/j.ab.2015.05.020. Epub 2015 Jun 4.

30.

Characterization of the inflammatory response to inhaled lipopolysaccharide in mild to moderate chronic obstructive pulmonary disease.

Gupta V, Banyard A, Mullan A, Sriskantharajah S, Southworth T, Singh D.

Br J Clin Pharmacol. 2015 May;79(5):767-76. doi: 10.1111/bcp.12546.

31.

A Photinus pyralis and Luciola italica chimeric firefly luciferase produces enhanced bioluminescence.

Branchini BR, Southworth TL, Fontaine DM, Davis AL, Behney CE, Murtiashaw MH.

Biochemistry. 2014 Oct 14;53(40):6287-9. doi: 10.1021/bi501202u. Epub 2014 Oct 1.

PMID:
25264115
32.

High- and low-dose allergen challenges in asthmatic patients using inhaled corticosteroids.

Lee WY, Southworth T, Booth S, Singh D.

Br J Clin Pharmacol. 2015 Mar;79(3):523-32. doi: 10.1111/bcp.12508.

33.

Microwave-specific acceleration of a Friedel-Crafts reaction: evidence for selective heating in homogeneous solution.

Rosana MR, Hunt J, Ferrari A, Southworth TA, Tao Y, Stiegman AE, Dudley GB.

J Org Chem. 2014 Aug 15;79(16):7437-50. doi: 10.1021/jo501153r. Epub 2014 Aug 1.

PMID:
25050855
34.

Chemical Analysis of the Luminous Slime Secreted by the Marine Worm Chaetopterus (Annelida, Polychaeta).

Branchini BR, Behney CE, Southworth TL, Rawat R, Deheyn DD.

Photochem Photobiol. 2014 Jan;90(1):247-51. doi: 10.1111/php.12169. Epub 2013 Oct 17.

PMID:
24004150
35.

Novel heterocyclic analogues of firefly luciferin.

Woodroofe CC, Meisenheimer PL, Klaubert DH, Kovic Y, Rosenberg JC, Behney CE, Southworth TL, Branchini BR.

Biochemistry. 2012 Dec 11;51(49):9807-13. doi: 10.1021/bi301411d. Epub 2012 Nov 29.

PMID:
23164087
36.

Crystal structure of firefly luciferase in a second catalytic conformation supports a domain alternation mechanism.

Sundlov JA, Fontaine DM, Southworth TL, Branchini BR, Gulick AM.

Biochemistry. 2012 Aug 21;51(33):6493-5. doi: 10.1021/bi300934s. Epub 2012 Aug 6.

37.

IFN-γ synergistically enhances LPS signalling in alveolar macrophages from COPD patients and controls by corticosteroid-resistant STAT1 activation.

Southworth T, Metryka A, Lea S, Farrow S, Plumb J, Singh D.

Br J Pharmacol. 2012 Aug;166(7):2070-83. doi: 10.1111/j.1476-5381.2012.01907.x.

38.

Bioluminescence is produced from a trapped firefly luciferase conformation predicted by the domain alternation mechanism.

Branchini BR, Rosenberg JC, Fontaine DM, Southworth TL, Behney CE, Uzasci L.

J Am Chem Soc. 2011 Jul 27;133(29):11088-91. doi: 10.1021/ja2041496. Epub 2011 Jul 1.

PMID:
21707059
39.

Sequential bioluminescence resonance energy transfer-fluorescence resonance energy transfer-based ratiometric protease assays with fusion proteins of firefly luciferase and red fluorescent protein.

Branchini BR, Rosenberg JC, Ablamsky DM, Taylor KP, Southworth TL, Linder SJ.

Anal Biochem. 2011 Jul 15;414(2):239-45. doi: 10.1016/j.ab.2011.03.031. Epub 2011 Mar 29.

PMID:
21453669
40.

Red-emitting luciferases for bioluminescence reporter and imaging applications.

Branchini BR, Ablamsky DM, Davis AL, Southworth TL, Butler B, Fan F, Jathoul AP, Pule MA.

Anal Biochem. 2010 Jan 15;396(2):290-7. doi: 10.1016/j.ab.2009.09.009. Epub 2009 Sep 11.

PMID:
19748472
41.

Seretide withdrawal increases airway inflammation in moderate COPD patients.

Borrill Z, Roy K, Kolsum U, Southworth T, Vestbo J, Singh D.

Eur J Clin Pharmacol. 2009 Nov;65(11):1165-6. doi: 10.1007/s00228-009-0697-5. Epub 2009 Jul 15. No abstract available.

PMID:
19603154
42.

Reduced exhaled breath condensate pH in asthmatic smokers using inhaled corticosteroids.

Kane B, Borrill Z, Southworth T, Woodcock A, Singh D.

Respirology. 2009 Apr;14(3):419-23.

PMID:
19353777
43.

alpha,beta-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases.

Moretto N, Facchinetti F, Southworth T, Civelli M, Singh D, Patacchini R.

Am J Physiol Lung Cell Mol Physiol. 2009 May;296(5):L839-48. doi: 10.1152/ajplung.90570.2008. Epub 2009 Mar 13.

44.

The effects of smoking on the lipopolysaccharide response and glucocorticoid sensitivity of alveolar macrophages of patients with asthma.

Kane B, Kolsum U, Southworth T, Armstrong J, Woodcock A, Singh D.

Chest. 2009 Jul;136(1):163-170. doi: 10.1378/chest.08-2633. Epub 2009 Feb 18.

PMID:
19225056
45.

Combining intracellular and secreted bioluminescent reporter proteins for multicolor cell-based assays.

Michelini E, Cevenini L, Mezzanotte L, Ablamsky D, Southworth T, Branchini BR, Roda A.

Photochem Photobiol Sci. 2008 Feb;7(2):212-7. doi: 10.1039/b714251j. Epub 2008 Jan 14.

PMID:
18264589
46.

Spectral-resolved gene technology for multiplexed bioluminescence and high-content screening.

Michelini E, Cevenini L, Mezzanotte L, Ablamsky D, Southworth T, Branchini B, Roda A.

Anal Chem. 2008 Jan 1;80(1):260-7. Epub 2007 Nov 22.

PMID:
18031021
47.

Synergistic mutations produce blue-shifted bioluminescence in firefly luciferase.

Branchini BR, Ablamsky DM, Rosenman JM, Uzasci L, Southworth TL, Zimmer M.

Biochemistry. 2007 Dec 4;46(48):13847-55. Epub 2007 Nov 10.

PMID:
17994766
48.

Thermostable red and green light-producing firefly luciferase mutants for bioluminescent reporter applications.

Branchini BR, Ablamsky DM, Murtiashaw MH, Uzasci L, Fraga H, Southworth TL.

Anal Biochem. 2007 Feb 15;361(2):253-62. Epub 2006 Nov 21.

PMID:
17181991
49.

Luciferase from the Italian firefly Luciola italica: molecular cloning and expression.

Branchini BR, Southworth TL, DeAngelis JP, Roda A, Michelini E.

Comp Biochem Physiol B Biochem Mol Biol. 2006 Oct;145(2):159-67. Epub 2006 Jun 8.

PMID:
16916615
50.

Effect of orthotics and footwear on static rearfoot kinematics.

Winkelmeyer M, Nelson B, Southworth T, Carlson K.

J Sports Sci Med. 2006 Sep 1;5(3):466-72. eCollection 2006.

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