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Items: 24

1.

Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2.

Hartford SA, Chittela R, Ding X, Vyas A, Martin B, Burkett S, Haines DC, Southon E, Tessarollo L, Sharan SK.

PLoS Genet. 2016 Aug 4;12(8):e1006236. doi: 10.1371/journal.pgen.1006236. eCollection 2016 Aug.

2.

Selenophosphate synthetase 1 is an essential protein with roles in regulation of redox homoeostasis in mammals.

Tobe R, Carlson BA, Huh JH, Castro NP, Xu XM, Tsuji PA, Lee SG, Bang J, Na JW, Kong YY, Beaglehole D, Southon E, Seifried H, Tessarollo L, Salomon DS, Schweizer U, Gladyshev VN, Hatfield DL, Lee BJ.

Biochem J. 2016 Jul 15;473(14):2141-54. doi: 10.1042/BCJ20160393. Epub 2016 May 16.

3.

BRCA2 minor transcript lacking exons 4-7 supports viability in mice and may account for survival of humans with a pathogenic biallelic mutation.

Thirthagiri E, Klarmann KD, Shukla AK, Southon E, Biswas K, Martin BK, North SL, Magidson V, Burkett S, Haines DC, Noer K, Matthai R, Tessarollo L, Loncarek J, Keller JR, Sharan SK.

Hum Mol Genet. 2016 May 15;25(10):1934-1945. Epub 2016 Feb 26.

4.

Fgf3-Fgf4-cis: A new mouse line for studying Fgf functions during mouse development.

Anderson MJ, Southon E, Tessarollo L, Lewandoski M.

Genesis. 2016 Feb;54(2):91-8. doi: 10.1002/dvg.22913. Epub 2016 Jan 14.

PMID:
26666435
5.

Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap).

Mahdi Y, Xu XM, Carlson BA, Fradejas N, Günter P, Braun D, Southon E, Tessarollo L, Hatfield DL, Schweizer U.

PLoS One. 2015 Jun 4;10(6):e0127349. doi: 10.1371/journal.pone.0127349. eCollection 2015.

6.

Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.

Hasumi H, Baba M, Hasumi Y, Lang M, Huang Y, Oh HF, Matsuo M, Merino MJ, Yao M, Ito Y, Furuya M, Iribe Y, Kodama T, Southon E, Tessarollo L, Nagashima K, Haines DC, Linehan WM, Schmidt LS.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1624-31. doi: 10.1073/pnas.1419502112. Epub 2015 Mar 16.

7.

Essential role of the zinc finger transcription factor Casz1 for mammalian cardiac morphogenesis and development.

Liu Z, Li W, Ma X, Ding N, Spallotta F, Southon E, Tessarollo L, Gaetano C, Mukouyama YS, Thiele CJ.

J Biol Chem. 2014 Oct 24;289(43):29801-16. doi: 10.1074/jbc.M114.570416. Epub 2014 Sep 4.

8.

The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development.

Baba M, Keller JR, Sun HW, Resch W, Kuchen S, Suh HC, Hasumi H, Hasumi Y, Kieffer-Kwon KR, Gonzalez CG, Hughes RM, Klein ME, Oh HF, Bible P, Southon E, Tessarollo L, Schmidt LS, Linehan WM, Casellas R.

Blood. 2012 Aug 9;120(6):1254-61. doi: 10.1182/blood-2012-02-410407. Epub 2012 Jun 18.

9.

Functional evaluation of BRCA2 variants mapping to the PALB2-binding and C-terminal DNA-binding domains using a mouse ES cell-based assay.

Biswas K, Das R, Eggington JM, Qiao H, North SL, Stauffer S, Burkett SS, Martin BK, Southon E, Sizemore SC, Pruss D, Bowles KR, Roa BB, Hunter N, Tessarollo L, Wenstrup RJ, Byrd RA, Sharan SK.

Hum Mol Genet. 2012 Sep 15;21(18):3993-4006. doi: 10.1093/hmg/dds222. Epub 2012 Jun 7.

10.

Regulation of trafficking of activated TrkA is critical for NGF-mediated functions.

Yu T, Calvo L, Anta B, López-Benito S, Southon E, Chao MV, Tessarollo L, Arévalo JC.

Traffic. 2011 Apr;12(4):521-34. doi: 10.1111/j.1600-0854.2010.01156.x. Epub 2011 Feb 1.

11.

Manipulating mouse embryonic stem cells.

Southon E, Tessarollo L.

Methods Mol Biol. 2009;530:165-85. doi: 10.1007/978-1-59745-471-1_9.

PMID:
19266324
12.

Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice.

Wang X, Rao RP, Kosakowska-Cholody T, Masood MA, Southon E, Zhang H, Berthet C, Nagashim K, Veenstra TK, Tessarollo L, Acharya U, Acharya JK.

J Cell Biol. 2009 Jan 12;184(1):143-58. doi: 10.1083/jcb.200807176.

13.

Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells.

Landry J, Sharov AA, Piao Y, Sharova LV, Xiao H, Southon E, Matta J, Tessarollo L, Zhang YE, Ko MS, Kuehn MR, Yamaguchi TP, Wu C.

PLoS Genet. 2008 Oct;4(10):e1000241. doi: 10.1371/journal.pgen.1000241. Epub 2008 Oct 31.

14.

An inducible and reversible mouse genetic rescue system.

Zeng H, Horie K, Madisen L, Pavlova MN, Gragerova G, Rohde AD, Schimpf BA, Liang Y, Ojala E, Kramer F, Roth P, Slobodskaya O, Dolka I, Southon EA, Tessarollo L, Bornfeldt KE, Gragerov A, Pavlakis GN, Gaitanaris GA.

PLoS Genet. 2008 May 9;4(5):e1000069. doi: 10.1371/journal.pgen.1000069.

15.

Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.

Baba M, Furihata M, Hong SB, Tessarollo L, Haines DC, Southon E, Patel V, Igarashi P, Alvord WG, Leighty R, Yao M, Bernardo M, Ileva L, Choyke P, Warren MB, Zbar B, Linehan WM, Schmidt LS.

J Natl Cancer Inst. 2008 Jan 16;100(2):140-54. doi: 10.1093/jnci/djm288. Epub 2008 Jan 8.

16.

RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females.

Kuznetsov S, Pellegrini M, Shuda K, Fernandez-Capetillo O, Liu Y, Martin BK, Burkett S, Southon E, Pati D, Tessarollo L, West SC, Donovan PJ, Nussenzweig A, Sharan SK.

J Cell Biol. 2007 Feb 26;176(5):581-92. Epub 2007 Feb 20.

17.

Novel tumor necrosis factor-knockout mice that lack Peyer's patches.

Kuprash DV, Tumanov AV, Liepinsh DJ, Koroleva EP, Drutskaya MS, Kruglov AA, Shakhov AN, Southon E, Murphy WJ, Tessarollo L, Grivennikov SI, Nedospasov SA.

Eur J Immunol. 2005 May;35(5):1592-600.

18.

Ablation of TrkA function in the immune system causes B cell abnormalities.

Coppola V, Barrick CA, Southon EA, Celeste A, Wang K, Chen B, Haddad el-B, Yin J, Nussenzweig A, Subramaniam A, Tessarollo L.

Development. 2004 Oct;131(20):5185-95.

19.

Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene.

Ma W, Tessarollo L, Hong SB, Baba M, Southon E, Back TC, Spence S, Lobe CG, Sharma N, Maher GW, Pack S, Vortmeyer AO, Guo C, Zbar B, Schmidt LS.

Cancer Res. 2003 Sep 1;63(17):5320-8.

20.

Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium.

Kumaraswamy E, Carlson BA, Morgan F, Miyoshi K, Robinson GW, Su D, Wang S, Southon E, Tessarollo L, Lee BJ, Gladyshev VN, Hennighausen L, Hatfield DL.

Mol Cell Biol. 2003 Mar;23(5):1477-88.

21.

Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP.

Taylor GA, Collazo CM, Yap GS, Nguyen K, Gregorio TA, Taylor LS, Eagleson B, Secrest L, Southon EA, Reid SW, Tessarollo L, Bray M, McVicar DW, Komschlies KL, Young HA, Biron CA, Sher A, Vande Woude GF.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):751-5.

22.

Oxidant inhibition of alphaLbeta2 integrin adhesion: evidence for coordinate effects on conformation and cytoskeleton linkage.

Edwards BS, Southon EA, Curry MS, Salazar F, Gale JM, Robinson MK, Graf LH Jr, Born JL.

J Leukoc Biol. 1998 Feb;63(2):190-202.

PMID:
9468277
24.

Activation of 72-kDa type IV collagenase/gelatinase by normal fibroblasts in collagen lattices is mediated by integrin receptors but is not related to lattice contraction.

Seltzer JL, Lee AY, Akers KT, Sudbeck B, Southon EA, Wayner EA, Eisen AZ.

Exp Cell Res. 1994 Aug;213(2):365-74.

PMID:
7519563

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