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Items: 1 to 50 of 151

1.

Blind deconvolution estimation of an arterial input function for small animal DCE-MRI.

Jiřík R, Taxt T, Macíček O, Bartoš M, Kratochvíla J, Souček K, Dražanová E, Krátká L, Hampl A, Starčuk Z Jr.

Magn Reson Imaging. 2019 Oct;62:46-56. doi: 10.1016/j.mri.2019.05.024. Epub 2019 May 28.

PMID:
31150814
2.

Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells.

Boudny M, Zemanova J, Khirsariya P, Borsky M, Verner J, Cerna J, Oltova A, Seda V, Mraz M, Jaros J, Jaskova Z, Spunarova M, Brychtova Y, Soucek K, Drapela S, Kasparkova M, Mayer J, Paruch K, Trbusek M.

Haematologica. 2019 Apr 11. pii: haematol.2018.203430. doi: 10.3324/haematol.2018.203430. [Epub ahead of print]

3.

High Skp2 expression is associated with a mesenchymal phenotype and increased tumorigenic potential of prostate cancer cells.

Šimečková Š, Kahounová Z, Fedr R, Remšík J, Slabáková E, Suchánková T, Procházková J, Bouchal J, Kharaishvili G, Král M, Beneš P, Souček K.

Sci Rep. 2019 Apr 5;9(1):5695. doi: 10.1038/s41598-019-42131-y.

4.

Generation of human iPSCs from fetal prostate fibroblasts HPrF.

Kahounová Z, Slabáková E, Binó L, Remšík J, Fedr R, Bouchal J, Vrtěl R, Jurečková L, Porokh V, Páralová D, Hampl A, Souček K.

Stem Cell Res. 2019 Mar;35:101405. doi: 10.1016/j.scr.2019.101405. Epub 2019 Feb 7.

5.

LC-MS/MS study of in vivo fate of hyaluronan polymeric micelles carrying doxorubicin.

Šimek M, Hermannová M, Šmejkalová D, Foglová T, Souček K, Binó L, Velebný V.

Carbohydr Polym. 2019 Apr 1;209:181-189. doi: 10.1016/j.carbpol.2018.12.104. Epub 2019 Jan 3.

PMID:
30732797
6.

Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.

Němec V, Hylsová M, Maier L, Flegel J, Sievers S, Ziegler S, Schröder M, Berger BT, Chaikuad A, Valčíková B, Uldrijan S, Drápela S, Souček K, Waldmann H, Knapp S, Paruch K.

Angew Chem Int Ed Engl. 2019 Jan 21;58(4):1062-1066. doi: 10.1002/anie.201810312. Epub 2018 Dec 20.

PMID:
30569600
7.

Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A.

Kahounová Z, Slabáková E, Binó L, Remšík J, Fedr R, Bouchal J, Kurfűrstová D, Vrtěl R, Študent V, Jurečková L, Porokh V, Hampl A, Souček K.

Stem Cell Res. 2018 Dec;33:255-259. doi: 10.1016/j.scr.2018.11.006. Epub 2018 Nov 16.

8.

In vivo monitoring of tumor distribution of hyaluronan polymeric micelles labeled or loaded with near-infrared fluorescence dye.

Achbergerová E, Šmejkalová D, Huerta-Angeles G, Souček K, Hermannová M, Vágnerová H, Vícha R, Velebný V.

Carbohydr Polym. 2018 Oct 15;198:339-347. doi: 10.1016/j.carbpol.2018.06.082. Epub 2018 Jun 22.

PMID:
30093008
9.

Correction Alternative mechanisms of miR-34a regulation in cancer.

Slabáková E, Culig Z, Remšík J, Souček K.

Cell Death Dis. 2018 Jul 16;9(8):783. doi: 10.1038/s41419-018-0833-1.

10.

Trop-2 plasticity is controlled by epithelial-to-mesenchymal transition.

Remšík J, Binó L, Kahounová Z, Kharaishvili G, Šimecková Š, Fedr R, Kucírková T, Lenárt S, Muresan XM, Slabáková E, Knopfová L, Bouchal J, Král M, Beneš P, Soucek K.

Carcinogenesis. 2018 Dec 13;39(11):1411-1418. doi: 10.1093/carcin/bgy095.

PMID:
30010814
11.

Presence of growth/differentiation factor-15 cytokine in human follicular fluid, granulosa cells, and oocytes.

Souček K, Malenovská A, Kahounová Z, Remšík J, Holubcová Z, Soukup T, Kurfürstová D, Bouchal J, Suchánková T, Slabáková E, Hampl A.

J Assist Reprod Genet. 2018 Aug;35(8):1407-1417. doi: 10.1007/s10815-018-1230-5. Epub 2018 Jun 13.

12.

Soluble Cripto-1 Induces Accumulation of Supernumerary Centrosomes and Formation of Aberrant Mitoses in Human Embryonic Stem Cells.

Porokh V, Vaňhara P, Bárta T, Jurečková L, Bohačiaková D, Pospíšilová V, Mináriková D, Holubcová Z, Pelková V, Souček K, Hampl A.

Stem Cells Dev. 2018 Aug 15;27(16):1077-1084. doi: 10.1089/scd.2018.0017. Epub 2018 Jul 17.

PMID:
29882484
13.

Flow Cytometric Analysis of Nucleoside Transporters Activity in Chemoresistant Prostate Cancer Model.

Drápela S, Fedr R, Khirsariya P, Paruch K, Svoboda M, Souček K.

Klin Onkol. Spring 2018;31(Supplementum1):140-144.

PMID:
29808688
14.

Hematological findings in non-treated and gamma-irradiated mice deficient for MIC-1/GDF15.

Hofer M, Hoferová Z, Remšík J, Nováková M, Procházková J, Fedr R, Kohoutek J, Dušek L, Hampl A, Souček K.

Physiol Res. 2018 Aug 16;67(4):623-636. Epub 2018 May 10.

15.

Hypericin affects cancer side populations via competitive inhibition of BCRP.

Vargová J, Mikeš J, Jendželovský R, Mikešová L, Kuchárová B, Čulka Ľ, Fedr R, Remšík J, Souček K, Kozubík A, Fedoročko P.

Biomed Pharmacother. 2018 Mar;99:511-522. doi: 10.1016/j.biopha.2018.01.074. Epub 2018 Feb 20.

PMID:
29665654
16.

Plasticity and intratumoural heterogeneity of cell surface antigen expression in breast cancer.

Remšík J, Fedr R, Navrátil J, Binó L, Slabáková E, Fabian P, Svoboda M, Souček K.

Br J Cancer. 2018 Mar 20;118(6):813-819. doi: 10.1038/bjc.2017.497. Epub 2018 Feb 20.

17.

Metabolic stress regulates ERK activity by controlling KSR-RAF heterodimerization.

Verlande A, Krafčíková M, Potěšil D, Trantírek L, Zdráhal Z, Elkalaf M, Trnka J, Souček K, Rauch N, Rauch J, Kolch W, Uldrijan S.

EMBO Rep. 2018 Feb;19(2):320-336. doi: 10.15252/embr.201744524. Epub 2017 Dec 20.

18.

Comparative cell cycle transcriptomics reveals synchronization of developmental transcription factor networks in cancer cells.

Boström J, Sramkova Z, Salašová A, Johard H, Mahdessian D, Fedr R, Marks C, Medalová J, Souček K, Lundberg E, Linnarsson S, Bryja V, Sekyrova P, Altun M, Andäng M.

PLoS One. 2017 Dec 11;12(12):e0188772. doi: 10.1371/journal.pone.0188772. eCollection 2017.

19.

Multiparameter cytometric analysis of complex cellular response.

Šimečková Š, Fedr R, Remšík J, Kahounová Z, Slabáková E, Souček K.

Cytometry A. 2018 Feb;93(2):239-248. doi: 10.1002/cyto.a.23295. Epub 2017 Dec 8.

20.

Transcription factor c-Myb inhibits breast cancer lung metastasis by suppression of tumor cell seeding.

Knopfová L, Biglieri E, Volodko N, Masařík M, Hermanová M, Glaus Garzón JF, Dúcka M, Kučírková T, Souček K, Šmarda J, Beneš P, Borsig L.

Oncogene. 2018 Feb 22;37(8):1020-1030. doi: 10.1038/onc.2017.392. Epub 2017 Oct 30.

21.

BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors.

Paculová H, Kramara J, Šimečková Š, Fedr R, Souček K, Hylse O, Paruch K, Svoboda M, Mistrík M, Kohoutek J.

Tumour Biol. 2017 Oct;39(10):1010428317727479. doi: 10.1177/1010428317727479.

PMID:
29025359
22.

Alternative mechanisms of miR-34a regulation in cancer.

Slabáková E, Culig Z, Remšík J, Souček K.

Cell Death Dis. 2017 Oct 12;8(10):e3100. doi: 10.1038/cddis.2017.495. Review. Erratum in: Cell Death Dis. 2018 Jul 16;9(8):783.

23.

Chk1 Inhibitor SCH900776 Effectively Potentiates the Cytotoxic Effects of Platinum-Based Chemotherapeutic Drugs in Human Colon Cancer Cells.

Herůdková J, Paruch K, Khirsariya P, Souček K, Krkoška M, Vondálová Blanářová O, Sova P, Kozubík A, Hyršlová Vaculová A.

Neoplasia. 2017 Oct;19(10):830-841. doi: 10.1016/j.neo.2017.08.002. Epub 2017 Sep 6.

24.

Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation.

Samadder P, Suchánková T, Hylse O, Khirsariya P, Nikulenkov F, Drápela S, Straková N, Vaňhara P, Vašíčková K, Kolářová H, Binó L, Bittová M, Ovesná P, Kollár P, Fedr R, Ešner M, Jaroš J, Hampl A, Krejčí L, Paruch K, Souček K.

Mol Cancer Ther. 2017 Sep;16(9):1831-1842. doi: 10.1158/1535-7163.MCT-17-0018. Epub 2017 Jun 15.

25.

Hematological profile of untreated or ionizing radiation-exposed cyclooxygenase-2-deficient mice.

Hofer M, Hoferová Z, Dušek L, Souček K, Gruzdev A.

Physiol Res. 2017 Sep 22;66(4):673-676. Epub 2017 Apr 12.

26.

The fibroblast surface markers FAP, anti-fibroblast, and FSP are expressed by cells of epithelial origin and may be altered during epithelial-to-mesenchymal transition.

Kahounová Z, Kurfürstová D, Bouchal J, Kharaishvili G, Navrátil J, Remšík J, Šimečková Š, Študent V, Kozubík A, Souček K.

Cytometry A. 2018 Jul;93(9):941-951. doi: 10.1002/cyto.a.23101. Epub 2017 Apr 6.

27.

Diastereoselective Flexible Synthesis of Carbocyclic C-Nucleosides.

Maier L, Khirsariya P, Hylse O, Adla SK, Černová L, Poljak M, Krajčovičová S, Weis E, Drápela S, Souček K, Paruch K.

J Org Chem. 2017 Apr 7;82(7):3382-3402. doi: 10.1021/acs.joc.6b02594. Epub 2017 Mar 20.

PMID:
28267331
28.

The dual role of asporin in breast cancer progression.

Simkova D, Kharaishvili G, Korinkova G, Ozdian T, Suchánková-Kleplová T, Soukup T, Krupka M, Galandakova A, Dzubak P, Janikova M, Navratil J, Kahounova Z, Soucek K, Bouchal J.

Oncotarget. 2016 Aug 9;7(32):52045-52060. doi: 10.18632/oncotarget.10471.

29.

Lung Neutrophilia in Myeloperoxidase Deficient Mice during the Course of Acute Pulmonary Inflammation.

Kremserova S, Perecko T, Soucek K, Klinke A, Baldus S, Eiserich JP, Kubala L.

Oxid Med Cell Longev. 2016;2016:5219056. doi: 10.1155/2016/5219056. Epub 2016 Feb 21.

30.

Exacerbation of substrate toxicity by IPTG in Escherichia coli BL21(DE3) carrying a synthetic metabolic pathway.

Dvorak P, Chrast L, Nikel PI, Fedr R, Soucek K, Sedlackova M, Chaloupkova R, de Lorenzo V, Prokop Z, Damborsky J.

Microb Cell Fact. 2015 Dec 21;14:201. doi: 10.1186/s12934-015-0393-3.

31.

Opposite regulation of MDM2 and MDMX expression in acquisition of mesenchymal phenotype in benign and cancer cells.

Slabáková E, Kharaishvili G, Smějová M, Pernicová Z, Suchánková T, Remšík J, Lerch S, Straková N, Bouchal J, Král M, Culig Z, Kozubík A, Souček K.

Oncotarget. 2015 Nov 3;6(34):36156-71. doi: 10.18632/oncotarget.5392.

32.

Flavonoid 4'-O-Methylkuwanon E from Morus alba Induces the Differentiation of THP-1 Human Leukemia Cells.

Kollar P, Bárta T, Keltošová S, Trnová P, Müller Závalová V, Šmejkal K, Hošek J, Fedr R, Souček K, Hampl A.

Evid Based Complement Alternat Med. 2015;2015:251895. doi: 10.1155/2015/251895. Epub 2015 Feb 9.

33.

Tumor suppressor candidate 3 (TUSC3) prevents the epithelial-to-mesenchymal transition and inhibits tumor growth by modulating the endoplasmic reticulum stress response in ovarian cancer cells.

Kratochvílová K, Horak P, Ešner M, Souček K, Pils D, Anees M, Tomasich E, Dráfi F, Jurtíková V, Hampl A, Krainer M, Vaňhara P.

Int J Cancer. 2015 Sep 15;137(6):1330-40. doi: 10.1002/ijc.29502. Epub 2015 Mar 21.

34.

Risk factors for development of spontaneous bacterial peritonitis and subsequent mortality in cirrhotic patients with ascites.

Schwabl P, Bucsics T, Soucek K, Mandorfer M, Bota S, Blacky A, Hirschl AM, Ferlitsch A, Trauner M, Peck-Radosavljevic M, Reiberger T.

Liver Int. 2015 Sep;35(9):2121-8. doi: 10.1111/liv.12795. Epub 2015 Feb 18.

PMID:
25644943
35.

Blind deconvolution in dynamic contrast-enhanced MRI and ultrasound.

Jiřík R, Souček K, Mézl M, Bartoš M, Dražanová E, Dráfi F, Grossová L, Kratochvíla J, Macíček O, Nylund K, Hampl A, Gilja OH, Taxt T, Starčuk Z Jr.

Conf Proc IEEE Eng Med Biol Soc. 2014;2014:4276-9. doi: 10.1109/EMBC.2014.6944569.

PMID:
25570937
36.

The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid.

Steinmetz B, Hackl H, Slabáková E, Schwarzinger I, Smějová M, Spittler A, Arbesu I, Shehata M, Souček K, Wieser R.

Cell Cycle. 2014;13(18):2931-43. doi: 10.4161/15384101.2014.946869. Erratum in: Cell Cycle. 2015;14(11):1759.

37.

Phthalates deregulate cell proliferation, but not neuroendocrine transdifferentiation, in human LNCaP prostate cancer cell model.

Hrubá E, Pernicová Z, Pálková L, Souček K, Vondráček J, Machala M.

Folia Biol (Praha). 2014;60 Suppl 1:56-61.

PMID:
25369342
38.

Utilization of an automated pipetting system in the cell line-based screening of the activity of a DNA-damaging anti-tumour drug.

Suchánková T, Ovesná P, Samadder P, Souček K.

Folia Biol (Praha). 2014;60 Suppl 1:50-5.

PMID:
25369341
39.

Properties of neural crest-like cells differentiated from human embryonic stem cells.

Křivánek J, Švandová E, Králik J, Hajda Š, Fedr R, Vinarský V, Jaroš J, Souček K, Buchtová M, Matalová E, Hampl A.

Folia Biol (Praha). 2014;60 Suppl 1:30-8.

PMID:
25369338
40.

The role of high cell density in the promotion of neuroendocrine transdifferentiation of prostate cancer cells.

Pernicová Z, Slabáková E, Fedr R, Šimečková Š, Jaroš J, Suchánková T, Bouchal J, Kharaishvili G, Král M, Kozubík A, Souček K.

Mol Cancer. 2014 May 20;13:113. doi: 10.1186/1476-4598-13-113.

41.

Pharmacokinetics, pharmacodynamics, and immunogenicity of belatacept in adult kidney transplant recipients.

Shen J, Townsend R, You X, Shen Y, Zhan P, Zhou Z, Geng D, Wu D, McGirr N, Soucek K, Proszynski E, Pursley J, Masson E.

Clin Drug Investig. 2014 Feb;34(2):117-26. doi: 10.1007/s40261-013-0153-2.

42.
43.

Prenylated Flavonoids from Morus alba L. Cause Inhibition of G1/S Transition in THP-1 Human Leukemia Cells and Prevent the Lipopolysaccharide-Induced Inflammatory Response.

Kollar P, Bárta T, Hošek J, Souček K, Závalová VM, Artinian S, Talhouk R, Smejkal K, Suchý P Jr, Hampl A.

Evid Based Complement Alternat Med. 2013;2013:350519. doi: 10.1155/2013/350519. Epub 2013 May 20.

44.

Automatic cell cloning assay for determining the clonogenic capacity of cancer and cancer stem-like cells.

Fedr R, Pernicová Z, Slabáková E, Straková N, Bouchal J, Grepl M, Kozubík A, Souček K.

Cytometry A. 2013 May;83(5):472-82. doi: 10.1002/cyto.a.22273. Epub 2013 Feb 28.

45.

Alternative Pathways of Cancer Cell Death by Rottlerin: Apoptosis versus Autophagy.

Torricelli C, Salvadori S, Valacchi G, Souček K, Slabáková E, Muscettola M, Volpi N, Maioli E.

Evid Based Complement Alternat Med. 2012;2012:980658. doi: 10.1155/2012/980658. Epub 2012 Dec 20.

46.

TGF-β1 signaling plays a dominant role in the crosstalk between TGF-β1 and the aryl hydrocarbon receptor ligand in prostate epithelial cells.

Staršíchová A, Hrubá E, Slabáková E, Pernicová Z, Procházková J, Pěnčíková K, Seda V, Kabátková M, Vondráček J, Kozubík A, Machala M, Souček K.

Cell Signal. 2012 Aug;24(8):1665-76. doi: 10.1016/j.cellsig.2012.04.008. Epub 2012 Apr 25.

PMID:
22560882
47.

c-Myb regulates matrix metalloproteinases 1/9, and cathepsin D: implications for matrix-dependent breast cancer cell invasion and metastasis.

Knopfová L, Beneš P, Pekarčíková L, Hermanová M, Masařík M, Pernicová Z, Souček K, Smarda J.

Mol Cancer. 2012 Mar 23;11:15. doi: 10.1186/1476-4598-11-15.

48.

Growth/differentiation factor-15: prostate cancer suppressor or promoter?

Vaňhara P, Hampl A, Kozubík A, Souček K.

Prostate Cancer Prostatic Dis. 2012 Dec;15(4):320-8. doi: 10.1038/pcan.2012.6. Epub 2012 Feb 28. Review.

PMID:
22370725
49.

Gene expression changes in human prostate carcinoma cells exposed to genotoxic and nongenotoxic aryl hydrocarbon receptor ligands.

Hrubá E, Vondráček J, Líbalová H, Topinka J, Bryja V, Souček K, Machala M.

Toxicol Lett. 2011 Oct 10;206(2):178-88. doi: 10.1016/j.toxlet.2011.07.011. Epub 2011 Jul 23.

PMID:
21802500
50.

Androgen depletion induces senescence in prostate cancer cells through down-regulation of Skp2.

Pernicová Z, Slabáková E, Kharaishvili G, Bouchal J, Král M, Kunická Z, Machala M, Kozubík A, Souček K.

Neoplasia. 2011 Jun;13(6):526-36.

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