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Items: 1 to 50 of 56

1.

Kdm6a Deficiency Activates Inflammatory Pathways, Promotes M2 Macrophage Polarization, and Causes Bladder Cancer in Cooperation with p53 Dysfunction.

Kobatake K, Ikeda KI, Nakata Y, Yamasaki N, Ueda T, Kanai A, Sentani K, Sera Y, Hayashi T, Koizumi M, Miyakawa Y, Inaba T, Sotomaru Y, Kaminuma O, Ichinohe T, Honda ZI, Yasui W, Horie S, Black PC, Matsubara A, Honda H.

Clin Cancer Res. 2020 Feb 11. doi: 10.1158/1078-0432.CCR-19-2230. [Epub ahead of print]

PMID:
32047002
2.

The matrix vesicle cargo miR-125b accumulates in the bone matrix, inhibiting bone resorption in mice.

Minamizaki T, Nakao Y, Irie Y, Ahmed F, Itoh S, Sarmin N, Yoshioka H, Nobukiyo A, Fujimoto C, Niida S, Sotomaru Y, Tanimoto K, Kozai K, Sugiyama T, Bonnelye E, Takei Y, Yoshiko Y.

Commun Biol. 2020 Jan 16;3(1):30. doi: 10.1038/s42003-020-0754-2.

3.

The serum amyloid A3 promoter-driven luciferase reporter mice is a valuable tool to image early renal fibrosis development and shows the therapeutic effect of glucosyl-hesperidin treatment.

Kumrungsee T, Kariya T, Hashimoto K, Koyano T, Yazawa N, Hashimoto T, Sanada Y, Matsuyama M, Sotomaru Y, Sakurai H, van de Loo FAJ, Yanaka N.

Sci Rep. 2019 Oct 1;9(1):14101. doi: 10.1038/s41598-019-50685-0.

4.

Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure.

Sano T, Sanada T, Sotomaru Y, Shinjo T, Iwashita M, Yamashita A, Fukuda T, Sanui T, Asano T, Kanematsu T, Nishimura F.

Nutr Metab (Lond). 2019 Jul 4;16:43. doi: 10.1186/s12986-019-0372-5. eCollection 2019.

5.

Synbiotics suppress colitis-induced tumorigenesis in a colon-specific cancer mouse model.

Saito Y, Hinoi T, Adachi T, Miguchi M, Niitsu H, Kochi M, Sada H, Sotomaru Y, Sakamoto N, Sentani K, Oue N, Yasui W, Tashiro H, Ohdan H.

PLoS One. 2019 Jun 26;14(6):e0216393. doi: 10.1371/journal.pone.0216393. eCollection 2019.

6.

XY oocytes of sex-reversed females with a Sry mutation deviate from the normal developmental process beyond the mitotic stage†.

Sakashita A, Wakai T, Kawabata Y, Nishimura C, Sotomaru Y, Alavattam KG, Namekawa SH, Kono T.

Biol Reprod. 2019 Mar 1;100(3):697-710. doi: 10.1093/biolre/ioy214.

7.

Transgenic mice specifically expressing amphiregulin in white adipose tissue showed less adipose tissue mass.

Yang B, Kumoto T, Arima T, Nakamura M, Sanada Y, Kumrungsee T, Sotomaru Y, Shimada M, Yanaka N.

Genes Cells. 2018 Mar;23(3):136-145. doi: 10.1111/gtc.12558. Epub 2018 Jan 17.

8.

The Role of Cysteine String Protein α Phosphorylation at Serine 10 and 34 by Protein Kinase Cγ for Presynaptic Maintenance.

Shirafuji T, Ueyama T, Adachi N, Yoshino KI, Sotomaru Y, Uwada J, Kaneoka A, Ueda T, Tanaka S, Hide I, Saito N, Sakai N.

J Neurosci. 2018 Jan 10;38(2):278-290. doi: 10.1523/JNEUROSCI.1649-17.2017. Epub 2017 Nov 22.

9.

Quality of common marmoset (Callithrix jacchus) oocytes collected after ovarian stimulation.

Kanda A, Nobukiyo A, Yoshioka M, Hatakeyama T, Sotomaru Y.

Theriogenology. 2018 Jan 15;106:221-226. doi: 10.1016/j.theriogenology.2017.10.023. Epub 2017 Oct 22.

PMID:
29096269
10.

Overexpression of microRNAs from the Gtl2-Rian locus contributes to postnatal death in mice.

Kumamoto S, Takahashi N, Nomura K, Fujiwara M, Kijioka M, Uno Y, Matsuda Y, Sotomaru Y, Kono T.

Hum Mol Genet. 2017 Oct 1;26(19):3653-3662. doi: 10.1093/hmg/ddx223.

11.

Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation.

Miguchi M, Hinoi T, Shimomura M, Adachi T, Saito Y, Niitsu H, Kochi M, Sada H, Sotomaru Y, Ikenoue T, Shigeyasu K, Tanakaya K, Kitadai Y, Sentani K, Oue N, Yasui W, Ohdan H.

PLoS One. 2016 Nov 11;11(11):e0166422. doi: 10.1371/journal.pone.0166422. eCollection 2016.

12.

KRAS mutation leads to decreased expression of regulator of calcineurin 2, resulting in tumor proliferation in colorectal cancer.

Niitsu H, Hinoi T, Kawaguchi Y, Sentani K, Yuge R, Kitadai Y, Sotomaru Y, Adachi T, Saito Y, Miguchi M, Kochi M, Sada H, Shimomura M, Oue N, Yasui W, Ohdan H.

Oncogenesis. 2016 Aug 15;5(8):e253. doi: 10.1038/oncsis.2016.47.

13.

Transcriptional regulator Bhlhe40 works as a cofactor of T-bet in the regulation of IFN-γ production in iNKT cells.

Kanda M, Yamanaka H, Kojo S, Usui Y, Honda H, Sotomaru Y, Harada M, Taniguchi M, Suzuki N, Atsumi T, Wada H, Baghdadi M, Seino K.

Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):E3394-402. doi: 10.1073/pnas.1604178113. Epub 2016 May 25.

14.

Chlorinated Water Modulates the Development of Colorectal Tumors with Chromosomal Instability and Gut Microbiota in Apc-Deficient Mice.

Sasada T, Hinoi T, Saito Y, Adachi T, Takakura Y, Kawaguchi Y, Sotomaru Y, Sentani K, Oue N, Yasui W, Ohdan H.

PLoS One. 2015 Jul 17;10(7):e0132435. doi: 10.1371/journal.pone.0132435. eCollection 2015.

15.

Dynamics of genomic 5-hydroxymethylcytosine during mouse oocyte growth.

Sakashita A, Kobayashi H, Wakai T, Sotomaru Y, Hata K, Kono T.

Genes Cells. 2014 Aug;19(8):629-36. doi: 10.1111/gtc.12164. Epub 2014 Jul 4.

16.

Developmental expression of GPR3 in rodent cerebellar granule neurons is associated with cell survival and protects neurons from various apoptotic stimuli.

Tanaka S, Miyagi T, Dohi E, Seki T, Hide I, Sotomaru Y, Saeki Y, Antonio Chiocca E, Matsumoto M, Sakai N.

Neurobiol Dis. 2014 Aug;68:215-27. doi: 10.1016/j.nbd.2014.04.007. Epub 2014 Apr 24.

PMID:
24769160
17.

Characterization of common marmoset (Callithrix jacchus) bone marrow-derived mesenchymal stem cells.

Kanda A, Sotomaru Y, Nobukiyo A, Yamaoka E, Hiyama E.

Folia Histochem Cytobiol. 2013;51(4):292-9. doi: 10.5603/FHC.2013.0040.

18.

A study on cryoprotectant solution suitable for vitrification of rat two-cell stage embryos.

Eto T, Takahashi R, Kamisako T, Hioki K, Sotomaru Y.

Cryobiology. 2014 Feb;68(1):147-51. doi: 10.1016/j.cryobiol.2014.01.011. Epub 2014 Jan 21.

19.

Long-term serial cultivation of mouse induced pluripotent stem cells in serum-free and feeder-free defined medium.

Yamasaki S, Nabeshima K, Sotomaru Y, Taguchi Y, Mukasa H, Furue MK, Sato JD, Okamoto T.

Int J Dev Biol. 2013;57(9-10):715-24. doi: 10.1387/ijdb.130173to.

20.

Development of lymphoproliferative diseases by hypoxia inducible factor-1alpha is associated with prolonged lymphocyte survival.

Sueoka E, Sueoka-Aragane N, Sato A, Ide M, Nakamura H, Sotomaru Y, Taya C, Yonekawa H, Kitagawa T, Kubota Y, Kimura S, Nakachi K, Tanimoto K.

PLoS One. 2013 Apr 12;8(4):e57833. doi: 10.1371/journal.pone.0057833. Print 2013.

21.

Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks.

Kobayashi H, Sakurai T, Imai M, Takahashi N, Fukuda A, Yayoi O, Sato S, Nakabayashi K, Hata K, Sotomaru Y, Suzuki Y, Kono T.

PLoS Genet. 2012 Jan;8(1):e1002440. doi: 10.1371/journal.pgen.1002440. Epub 2012 Jan 5.

22.

Establishment of ES cells from inbred strain mice by dual inhibition (2i).

Kanda A, Sotomaru Y, Shiozawa S, Hiyama E.

J Reprod Dev. 2012;58(1):77-83. Epub 2011 Nov 4.

23.

Incisor enamel formation is impaired in transgenic rats overexpressing the type III NaPi transporter Slc20a1.

Yoshioka H, Yoshiko Y, Minamizaki T, Suzuki S, Koma Y, Nobukiyo A, Sotomaru Y, Suzuki A, Itoh M, Maeda N.

Calcif Tissue Int. 2011 Sep;89(3):192-202. doi: 10.1007/s00223-011-9506-0. Epub 2011 Jun 4.

PMID:
21643723
24.

Neoplastic transformation by TERT in FGF-2-expanded human mesenchymal stem cells.

Yamaoka E, Hiyama E, Sotomaru Y, Onitake Y, Fukuba I, Sudo T, Sueda T, Hiyama K.

Int J Oncol. 2011 Jul;39(1):5-11. doi: 10.3892/ijo.2011.1029. Epub 2011 May 3.

PMID:
21573488
25.

Gene targeting and subsequent site-specific transgenesis at the β-actin (ACTB) locus in common marmoset embryonic stem cells.

Shiozawa S, Kawai K, Okada Y, Tomioka I, Maeda T, Kanda A, Shinohara H, Suemizu H, James Okano H, Sotomaru Y, Sasaki E, Okano H.

Stem Cells Dev. 2011 Sep;20(9):1587-99. doi: 10.1089/scd.2010.0351. Epub 2011 Jan 16.

PMID:
21126169
26.

Identification of inappropriately reprogrammed genes by large-scale transcriptome analysis of individual cloned mouse blastocysts.

Fukuda A, Cao F, Morita S, Yamada K, Jincho Y, Tane S, Sotomaru Y, Kono T.

PLoS One. 2010 Jun 30;5(6):e11274. doi: 10.1371/journal.pone.0011274.

27.

Over-expression of Runx1 transcription factor impairs the development of thymocytes from the double-negative to double-positive stages.

Wong WF, Nakazato M, Watanabe T, Kohu K, Ogata T, Yoshida N, Sotomaru Y, Ito M, Araki K, Telfer J, Fukumoto M, Suzuki D, Sato T, Hozumi K, Habu S, Satake M.

Immunology. 2010 Jun;130(2):243-53. doi: 10.1111/j.1365-2567.2009.03230.x. Epub 2010 Jan 19.

28.

Preimplantation development of somatic cell cloned embryos in the common marmoset (Callithrix jacchus).

Sotomaru Y, Hirakawa R, Shimada A, Shiozawa S, Sugawara A, Oiwa R, Nobukiyo A, Okano H, Tamaoki N, Nomura T, Hiyama E, Sasaki E.

Cloning Stem Cells. 2009 Dec;11(4):575-83. doi: 10.1089/clo.2009.0005.

PMID:
20025525
29.

Generation of transgenic non-human primates with germline transmission.

Sasaki E, Suemizu H, Shimada A, Hanazawa K, Oiwa R, Kamioka M, Tomioka I, Sotomaru Y, Hirakawa R, Eto T, Shiozawa S, Maeda T, Ito M, Ito R, Kito C, Yagihashi C, Kawai K, Miyoshi H, Tanioka Y, Tamaoki N, Habu S, Okano H, Nomura T.

Nature. 2009 May 28;459(7246):523-7. doi: 10.1038/nature08090.

PMID:
19478777
30.

Developmental ability of trophoblast stem cells in uniparental mouse embryos.

Ogawa H, Shindo N, Kumagai T, Usami Y, Shikanai M, Jonwn K, Fukuda A, Kawahara M, Sotomaru Y, Tanaka S, Arima T, Kono T.

Placenta. 2009 May;30(5):448-56. doi: 10.1016/j.placenta.2009.02.006. Epub 2009 Apr 3.

PMID:
19345411
31.

Deletion of Gtl2, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice.

Takahashi N, Okamoto A, Kobayashi R, Shirai M, Obata Y, Ogawa H, Sotomaru Y, Kono T.

Hum Mol Genet. 2009 May 15;18(10):1879-88. doi: 10.1093/hmg/ddp108. Epub 2009 Mar 4.

PMID:
19264764
32.

Identification of the mouse paternally expressed imprinted gene Zdbf2 on chromosome 1 and its imprinted human homolog ZDBF2 on chromosome 2.

Kobayashi H, Yamada K, Morita S, Hiura H, Fukuda A, Kagami M, Ogata T, Hata K, Sotomaru Y, Kono T.

Genomics. 2009 May;93(5):461-72. doi: 10.1016/j.ygeno.2008.12.012. Epub 2009 Feb 4.

33.

Exploration of the genes responsible for unlimited proliferation of immortalized lung fibroblasts.

Hiyama K, Tanimoto K, Nishimura Y, Tsugane M, Fukuba I, Sotomaru Y, Hiyama E, Nishiyama M.

Exp Lung Res. 2008 Sep;34(7):373-90. doi: 10.1080/01902140802221912.

PMID:
18716925
34.

Protocol for the production of viable bimaternal mouse embryos.

Kawahara M, Obata Y, Sotomaru Y, Shimozawa N, Bao S, Tsukadaira T, Fukuda A, Kono T.

Nat Protoc. 2008;3(2):197-209. doi: 10.1038/nprot.2007.531.

PMID:
18274521
35.

Identification of genes aberrantly expressed in mouse embryonic stem cell-cloned blastocysts.

Jincho Y, Sotomaru Y, Kawahara M, Ono Y, Ogawa H, Obata Y, Kono T.

Biol Reprod. 2008 Apr;78(4):568-76. Epub 2007 Oct 31.

PMID:
17978277
36.

Phenotypic abnormalities observed in aged cloned mice from embryonic stem cells after long-term maintenance.

Shimozawa N, Sotomaru Y, Eguchi N, Suzuki S, Hioki K, Usui T, Kono T, Ito M.

Reproduction. 2006 Sep;132(3):435-41.

PMID:
16940284
37.

Comprehensive analysis of myeloid lineage conversion using mice expressing an inducible form of C/EBP alpha.

Fukuchi Y, Shibata F, Ito M, Goto-Koshino Y, Sotomaru Y, Ito M, Kitamura T, Nakajima H.

EMBO J. 2006 Jul 26;25(14):3398-410. Epub 2006 Jul 6.

38.
39.

Current status of chromosomal abnormalities in mouse embryonic stem cell lines used in Japan.

Sugawara A, Goto K, Sotomaru Y, Sofuni T, Ito T.

Comp Med. 2006 Feb;56(1):31-4.

PMID:
16521857
40.

The role of leptin in the development of the cerebral cortex in mouse embryos.

Udagawa J, Hashimoto R, Suzuki H, Hatta T, Sotomaru Y, Hioki K, Kagohashi Y, Nomura T, Minami Y, Otani H.

Endocrinology. 2006 Feb;147(2):647-58. Epub 2005 Nov 10.

PMID:
16282354
41.

Estrous stage- and animal age-independent superovulation in the BrlHan:WIST@Jcl(GALAS) rat.

Sotomaru Y, Kamisako T, Hioki K.

Exp Anim. 2005 Apr;54(2):137-41.

42.

PCR method for genotyping and zygosity-testing of RasH2 transgenic mice.

Suemizu H, Kito-Maruyama C, Sotomaru Y, Ogura T, Hioki K, Ohnishi Y, Tamaoki N.

Exp Anim. 2004 Oct;53(5):463-6.

43.

Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo.

Hozumi K, Negishi N, Suzuki D, Abe N, Sotomaru Y, Tamaoki N, Mailhos C, Ish-Horowicz D, Habu S, Owen MJ.

Nat Immunol. 2004 Jun;5(6):638-44. Epub 2004 May 16.

PMID:
15146182
44.

Disruption of imprinting in cloned mouse fetuses from embryonic stem cells.

Ogawa H, Ono Y, Shimozawa N, Sotomaru Y, Katsuzawa Y, Hiura H, Ito M, Kono T.

Reproduction. 2003 Oct;126(4):549-57.

PMID:
14525537
45.

Imprinting of a small nucleolar RNA gene on mouse chromosome 12.

Shimoda M, Morita S, Obata Y, Sotomaru Y, Kono T, Hatada I.

Genomics. 2002 Apr;79(4):483-6.

PMID:
11944978
46.

Mouse parthenogenetic embryos with monoallelic H19 expression can develop to day 17.5 of gestation.

Kono T, Sotomaru Y, Katsuzawa Y, Dandolo L.

Dev Biol. 2002 Mar 15;243(2):294-300.

47.

Asb4, Ata3, and Dcn are novel imprinted genes identified by high-throughput screening using RIKEN cDNA microarray.

Mizuno Y, Sotomaru Y, Katsuzawa Y, Kono T, Meguro M, Oshimura M, Kawai J, Tomaru Y, Kiyosawa H, Nikaido I, Amanuma H, Hayashizaki Y, Okazaki Y.

Biochem Biophys Res Commun. 2002 Feb 8;290(5):1499-505.

PMID:
11820791
48.

Unregulated expression of the imprinted genes H19 and Igf2r in mouse uniparental fetuses.

Sotomaru Y, Katsuzawa Y, Hatada I, Obata Y, Sasaki H, Kono T.

J Biol Chem. 2002 Apr 5;277(14):12474-8. Epub 2002 Jan 22.

49.

Identification of a new imprinted gene, Rian, on mouse chromosome 12 by fluorescent differential display screening.

Hatada I, Morita S, Obata Y, Sotomaru Y, Shimoda M, Kono T.

J Biochem. 2001 Aug;130(2):187-90.

50.

Disruption of imprinted expression of U2afbp-rs/U2af1-rs1 gene in mouse parthenogenetic fetuses.

Sotomaru Y, Kawase Y, Ueda T, Obata Y, Suzuki H, Domeki I, Hatada I, Kono T.

J Biol Chem. 2001 Jul 13;276(28):26694-8. Epub 2001 Apr 16.

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